nordihydroguaiaretic acid-1648 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the nordihydroguaiaretic acid-1648 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAGAB alpha- and gamma-adaptin binding protein
ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9
AHNAK2 AHNAK nucleoprotein 2
AP3B1 adaptor-related protein complex 3, beta 1 subunit
AR androgen receptor
ARHGAP35 Rho GTPase activating protein 35
ARTN artemin
BAZ1B bromodomain adjacent to zinc finger domain, 1B
C14ORF93 chromosome 14 open reading frame 93
CA12 carbonic anhydrase XII
CCPG1 cell cycle progression 1
CFLAR CASP8 and FADD-like apoptosis regulator
CLIP2 CAP-GLY domain containing linker protein 2
CXCR4 chemokine (C-X-C motif) receptor 4
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
DHRS12 dehydrogenase/reductase (SDR family) member 12
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
DOC2A double C2-like domains, alpha
FARP2 FERM, RhoGEF and pleckstrin domain protein 2
FGF2 fibroblast growth factor 2 (basic)
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
HBEGF heparin-binding EGF-like growth factor
HIST1H2BC histone cluster 1, H2bc
HMOX1 heme oxygenase 1
HOMER3 homer scaffolding protein 3
HP1BP3 heterochromatin protein 1, binding protein 3
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11
IDS iduronate 2-sulfatase
IL1RAPL2 interleukin 1 receptor accessory protein-like 2
IPO8 importin 8
IQCK IQ motif containing K
KLF3 Kruppel-like factor 3 (basic)
LIN7A lin-7 homolog A (C. elegans)
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2
MAP4K5 mitogen-activated protein kinase kinase kinase kinase 5
MARK4 MAP/microtubule affinity-regulating kinase 4
MBNL2 muscleblind-like splicing regulator 2
MED14 mediator complex subunit 14
MMP25 matrix metallopeptidase 25
MOBP myelin-associated oligodendrocyte basic protein
MOCS1 molybdenum cofactor synthesis 1
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2)
NF2 neurofibromin 2 (merlin)
OLFML2A olfactomedin-like 2A
OLFML3 olfactomedin-like 3
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PIP4K2B phosphatidylinositol-5-phosphate 4-kinase, type II, beta
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PITX1 paired-like homeodomain 1
PLA2G3 phospholipase A2, group III
PLAC1 placenta-specific 1
PPP2R3A protein phosphatase 2, regulatory subunit B'', alpha
PPP2R5B protein phosphatase 2, regulatory subunit B', beta
PRKAR2A protein kinase, cAMP-dependent, regulatory, type II, alpha
PRLR prolactin receptor
PTCH1 patched 1
PTK6 protein tyrosine kinase 6
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PTPRA protein tyrosine phosphatase, receptor type, A
PYHIN1 pyrin and HIN domain family, member 1
RAB35 RAB35, member RAS oncogene family
RASA2 RAS p21 protein activator 2
RASA3 RAS p21 protein activator 3
RECQL5 RecQ protein-like 5
REPS1 RALBP1 associated Eps domain containing 1
ROCK2 Rho-associated, coiled-coil containing protein kinase 2
SCN1B sodium channel, voltage gated, type I beta subunit
SIX1 SIX homeobox 1
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SLC25A16 solute carrier family 25 (mitochondrial carrier), member 16
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2
SLCO1C1 solute carrier organic anion transporter family, member 1C1
SMAD4 SMAD family member 4
SNCG synuclein, gamma (breast cancer-specific protein 1)
SNX11 sorting nexin 11
STAG3 stromal antigen 3
STAG3L4 stromal antigen 3-like 4 (pseudogene)
STMN1 stathmin 1
STRA6 stimulated by retinoic acid 6
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
TCF3 transcription factor 3
TCP11L1 t-complex 11, testis-specific-like 1
TGFB1I1 transforming growth factor beta 1 induced transcript 1
TLN2 talin 2
TNFAIP2 tumor necrosis factor, alpha-induced protein 2
TRPV6 transient receptor potential cation channel, subfamily V, member 6
TSPAN9 tetraspanin 9
TTC9 tetratricopeptide repeat domain 9
TUBA3C tubulin, alpha 3c
UNC5B unc-5 homolog B (C. elegans)
VWA5A von Willebrand factor A domain containing 5A
ZFP36L2 ZFP36 ring finger protein-like 2
ZNF574 zinc finger protein 574
ZNF589 zinc finger protein 589

decreased expression

Symbol Name
ABCA11P ATP-binding cassette, sub-family A (ABC1), member 11, pseudogene
ALG12 ALG12, alpha-1,6-mannosyltransferase
ARHGAP10 Rho GTPase activating protein 10
ARRB2 arrestin, beta 2
ATP7B ATPase, Cu++ transporting, beta polypeptide
AXIN1 axin 1
BATF basic leucine zipper transcription factor, ATF-like
BEX4 brain expressed, X-linked 4
C19ORF40 chromosome 19 open reading frame 40
C1ORF56 chromosome 1 open reading frame 56
C4ORF29 chromosome 4 open reading frame 29
C9ORF40 chromosome 9 open reading frame 40
CCBL1 cysteine conjugate-beta lyase, cytoplasmic
CCDC186 coiled-coil domain containing 186
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CEP170B centrosomal protein 170B
CGA glycoprotein hormones, alpha polypeptide
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
CRY2 cryptochrome circadian clock 2
CTC1 CTS telomere maintenance complex component 1
CTSK cathepsin K
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DSCAM Down syndrome cell adhesion molecule
DZANK1 double zinc ribbon and ankyrin repeat domains 1
EFNA3 ephrin-A3
ELOVL4 ELOVL fatty acid elongase 4
EPPK1 epiplakin 1
ERN2 endoplasmic reticulum to nucleus signaling 2
FAAH fatty acid amide hydrolase
FBRS fibrosin
FBXO22 F-box protein 22
GLS2 glutaminase 2 (liver, mitochondrial)
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like
GUSBP3 glucuronidase, beta pseudogene 3
HIST1H2AJ histone cluster 1, H2aj
HSD17B1 hydroxysteroid (17-beta) dehydrogenase 1
IGFBP6 insulin-like growth factor binding protein 6
IL15RA interleukin 15 receptor, alpha
IRF2 interferon regulatory factor 2
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
ITPKB inositol-trisphosphate 3-kinase B
JADE3 jade family PHD finger 3
KAT2A K(lysine) acetyltransferase 2A
KCNMB3 potassium channel subfamily M regulatory beta subunit 3
LINC00339 long intergenic non-protein coding RNA 339
MAGOHB mago-nashi homolog B (Drosophila)
MAP7D1 MAP7 domain containing 1
MID1IP1 MID1 interacting protein 1
MYL5 myosin, light chain 5, regulatory
NDE1 nudE neurodevelopment protein 1
NUDT2 nudix (nucleoside diphosphate linked moiety X)-type motif 2
NUP62CL nucleoporin 62kDa C-terminal like
NUPL2 nucleoporin like 2
PARP16 poly (ADP-ribose) polymerase family, member 16
PCOLCE2 procollagen C-endopeptidase enhancer 2
PEX26 peroxisomal biogenesis factor 26
PIGH phosphatidylinositol glycan anchor biosynthesis, class H
PILRB paired immunoglobin-like type 2 receptor beta
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma
PLEKHG6 pleckstrin homology domain containing, family G (with RhoGef domain) member 6
PPP1R13L protein phosphatase 1, regulatory subunit 13 like
PTPN9 protein tyrosine phosphatase, non-receptor type 9
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RNF121 ring finger protein 121
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1
RPGR retinitis pigmentosa GTPase regulator
RPH3AL rabphilin 3A-like (without C2 domains)
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4
RWDD3 RWD domain containing 3
SETD8 SET domain containing (lysine methyltransferase) 8
SH2D4A SH2 domain containing 4A
SH3BGR SH3 domain binding glutamate-rich protein
SKA1 spindle and kinetochore associated complex subunit 1
SLC26A6 solute carrier family 26 (anion exchanger), member 6
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SPIN1 spindlin 1
TEAD3 TEA domain family member 3
THNSL1 threonine synthase-like 1 (S. cerevisiae)
THRAP3 thyroid hormone receptor associated protein 3
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13
TSPYL2 TSPY-like 2
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
UBXN6 UBX domain protein 6
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
VEGFC vascular endothelial growth factor C
VPS11 vacuolar protein sorting 11 homolog (S. cerevisiae)
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
WDR91 WD repeat domain 91
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
ZAK sterile alpha motif and leucine zipper containing kinase AZK
ZDHHC18 zinc finger, DHHC-type containing 18
ZNF280D zinc finger protein 280D
ZNF573 zinc finger protein 573
ZNF768 zinc finger protein 768
ZNF813 zinc finger protein 813
ZW10 zw10 kinetochore protein