nordihydroguaiaretic acid-1164 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the nordihydroguaiaretic acid-1164 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACACB acetyl-CoA carboxylase beta
ACOX1 acyl-CoA oxidase 1, palmitoyl
ADGRE1 adhesion G protein-coupled receptor E1
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AKAP10 A kinase (PRKA) anchor protein 10
ALDH1L1 aldehyde dehydrogenase 1 family, member L1
ALDH3B1 aldehyde dehydrogenase 3 family, member B1
ALOX12 arachidonate 12-lipoxygenase
ALPPL2 alkaline phosphatase, placental-like 2
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
ATF6B activating transcription factor 6 beta
ATP6V0A2 ATPase, H+ transporting, lysosomal V0 subunit a2
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
BACE1 beta-site APP-cleaving enzyme 1
BLZF1 basic leucine zipper nuclear factor 1
BTG2 BTG family, member 2
C19ORF66 chromosome 19 open reading frame 66
C5ORF45 chromosome 5 open reading frame 45
CACNA1I calcium channel, voltage-dependent, T type, alpha 1I subunit
CALM1 calmodulin 1 (phosphorylase kinase, delta)
CAMSAP2 calmodulin regulated spectrin-associated protein family, member 2
CCT8 chaperonin containing TCP1, subunit 8 (theta)
CDS2 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2
COMMD4 COMM domain containing 4
CPVL carboxypeptidase, vitellogenic-like
CTSZ cathepsin Z
DCAKD dephospho-CoA kinase domain containing
DHRS11 dehydrogenase/reductase (SDR family) member 11
DIAPH2-AS1 DIAPH2 antisense RNA 1
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DNASE2 deoxyribonuclease II, lysosomal
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
FBXO2 F-box protein 2
FCAR Fc fragment of IgA receptor
FKBP8 FK506 binding protein 8, 38kDa
FOXC1 forkhead box C1
GK glycerol kinase
H2AFX H2A histone family, member X
HEMK1 HemK methyltransferase family member 1
HOXC8 homeobox C8
IGHMBP2 immunoglobulin mu binding protein 2
IGL immunoglobulin lambda locus
ISG20 interferon stimulated exonuclease gene 20kDa
JUND jun D proto-oncogene
KIAA0087 KIAA0087
KIAA0319L KIAA0319-like
KLF6 Kruppel-like factor 6
KSR1 kinase suppressor of ras 1
LMF2 lipase maturation factor 2
LPPR2 lipid phosphate phosphatase-related protein type 2
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MINOS1P1 mitochondrial inner membrane organizing system 1 pseudogene 1
MMP25 matrix metallopeptidase 25
NAGPA N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
NF2 neurofibromin 2 (merlin)
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NPR2 natriuretic peptide receptor 2
NRP1 neuropilin 1
OR10J1 olfactory receptor, family 10, subfamily J, member 1
PAFAH2 platelet-activating factor acetylhydrolase 2, 40kDa
PAOX polyamine oxidase (exo-N4-amino)
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PLCD1 phospholipase C, delta 1
PLK3 polo-like kinase 3
PLK4 polo-like kinase 4
PNPLA4 patatin-like phospholipase domain containing 4
POLG polymerase (DNA directed), gamma
PVR poliovirus receptor
PYGB phosphorylase, glycogen; brain
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated)
RBCK1 RanBP-type and C3HC4-type zinc finger containing 1
RCAN3 RCAN family member 3
RPL10 ribosomal protein L10
SENP5 SUMO1/sentrin specific peptidase 5
SHB Src homology 2 domain containing adaptor protein B
SHOX2 short stature homeobox 2
SLC12A9 solute carrier family 12, member 9
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SMA4 glucuronidase, beta pseudogene
SMCO4 single-pass membrane protein with coiled-coil domains 4
SMEK1 SMEK homolog 1, suppressor of mek1 (Dictyostelium)
SOS2 son of sevenless homolog 2 (Drosophila)
SPAG1 sperm associated antigen 1
SPTB spectrin, beta, erythrocytic
SSBP3 single stranded DNA binding protein 3
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
STRN striatin, calmodulin binding protein
SULT1A2 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
TAX1BP3 Tax1 (human T-cell leukemia virus type I) binding protein 3
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TMEM231 transmembrane protein 231
TNS1 tensin 1
TRAF1 TNF receptor-associated factor 1
UTP14A UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast)
UTRN utrophin
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6
ZNF254 zinc finger protein 254
ZNF688 zinc finger protein 688

decreased expression

Symbol Name
ADAP2 ArfGAP with dual PH domains 2
ADPRM ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent
ARHGAP10 Rho GTPase activating protein 10
ARHGAP4 Rho GTPase activating protein 4
ASB7 ankyrin repeat and SOCS box containing 7
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1
B3GNT1
BAHCC1 BAH domain and coiled-coil containing 1
BAMBI BMP and activin membrane-bound inhibitor
BBS10 Bardet-Biedl syndrome 10
CALCOCO1 calcium binding and coiled-coil domain 1
CAPN15 calpain 15
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CGRRF1 cell growth regulator with ring finger domain 1
CHML choroideremia-like (Rab escort protein 2)
CHST10 carbohydrate sulfotransferase 10
CLEC4E C-type lectin domain family 4, member E
CPSF7 cleavage and polyadenylation specific factor 7, 59kDa
CXCL2 chemokine (C-X-C motif) ligand 2
DBF4B DBF4 zinc finger B
DDB2 damage-specific DNA binding protein 2, 48kDa
DENND1C DENN/MADD domain containing 1C
DGAT1 diacylglycerol O-acyltransferase 1
DOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1)
DVL1 dishevelled segment polarity protein 1
ELP6 elongator acetyltransferase complex subunit 6
ERN2 endoplasmic reticulum to nucleus signaling 2
ETV4 ets variant 4
FAM114A2 family with sequence similarity 114, member A2
FAM50B family with sequence similarity 50, member B
FANCF Fanconi anemia, complementation group F
FBXL7 F-box and leucine-rich repeat protein 7
FGGY FGGY carbohydrate kinase domain containing
GBF1 golgi brefeldin A resistant guanine nucleotide exchange factor 1
GLTSCR1 glioma tumor suppressor candidate region gene 1
GPALPP1 GPALPP motifs containing 1
GPR27 G protein-coupled receptor 27
GRINA glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)
KIF13B kinesin family member 13B
KLHDC4 kelch domain containing 4
LILRB4 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4
LMBR1L limb development membrane protein 1-like
MACROD1 MACRO domain containing 1
MAP7D3 MAP7 domain containing 3
MBTD1 mbt domain containing 1
MICALL1 MICAL-like 1
MPDU1 mannose-P-dolichol utilization defect 1
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MUL1 mitochondrial E3 ubiquitin protein ligase 1
MX2 MX dynamin-like GTPase 2
MYBBP1A MYB binding protein (P160) 1a
MYL5 myosin, light chain 5, regulatory
NFRKB nuclear factor related to kappaB binding protein
NME6 NME/NM23 nucleoside diphosphate kinase 6
NOC4L nucleolar complex associated 4 homolog (S. cerevisiae)
NPIPB15 nuclear pore complex interacting protein family, member B15
NR1D2 nuclear receptor subfamily 1, group D, member 2
PAQR4 progestin and adipoQ receptor family member IV
PHKG2 phosphorylase kinase, gamma 2 (testis)
PIEZO1 piezo-type mechanosensitive ion channel component 1
POLA2 polymerase (DNA directed), alpha 2, accessory subunit
PRAF2 PRA1 domain family, member 2
PTGES2 prostaglandin E synthase 2
RBM38 RNA binding motif protein 38
REEP4 receptor accessory protein 4
RNF121 ring finger protein 121
S100A12 S100 calcium binding protein A12
SASH3 SAM and SH3 domain containing 3
SCRIB scribbled planar cell polarity protein
SIPA1 signal-induced proliferation-associated 1
SLC25A10 solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
SLC25A22 solute carrier family 25 (mitochondrial carrier: glutamate), member 22
SLC38A6 solute carrier family 38, member 6
SNHG20 small nucleolar RNA host gene 20
SNHG3 small nucleolar RNA host gene 3
SRD5A3 steroid 5 alpha-reductase 3
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
TAF1A TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa
TERT telomerase reverse transcriptase
TMA16 translation machinery associated 16 homolog (S. cerevisiae)
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TSPYL2 TSPY-like 2
TSR2 TSR2, 20S rRNA accumulation, homolog (S. cerevisiae)
TTC26 tetratricopeptide repeat domain 26
TTF2 transcription termination factor, RNA polymerase II
UBP1 upstream binding protein 1 (LBP-1a)
URGCP upregulator of cell proliferation
XPNPEP3 X-prolyl aminopeptidase 3, mitochondrial
XYLT2 xylosyltransferase II
ZBTB44 zinc finger and BTB domain containing 44
ZMAT5 zinc finger, matrin-type 5
ZNF14 zinc finger protein 14
ZNF282 zinc finger protein 282
ZNF37BP zinc finger protein 37B, pseudogene
ZNF528 zinc finger protein 528
ZNF529 zinc finger protein 529
ZNF665 zinc finger protein 665
ZNF747 zinc finger protein 747