nonspecific interstitial pneumonia Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description An idiopathic interstitial pneumonia that occurs mainly in women, people who do not smoke, and people younger than 50 years with no known cause or risk factors. Lung biopsies may show predominantly interstitial inflammation or fibrosis or a combination of inflammation and fibrosis. A dry cough and shortness of breath develop over 6 to 18 months. Low-grade fever and a feeling of illness (malaise) may occur. (Human Disease Ontology, DOID_2801)
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Genes

74 genes co-occuring with the disease nonspecific interstitial pneumonia in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
MUC1 mucin 1, cell surface associated 1.42937
SFTPC surfactant protein C 1.40132
PROS2P protein S (beta) pseudogene 1.19014
SLC7A2 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 1.05934
SRXN1 sulfiredoxin 1 1.03704
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) 0.946186
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 0.935385
SLC7A6 solute carrier family 7 (amino acid transporter light chain, y+L system), member 6 0.917611
FHOD1 formin homology 2 domain containing 1 0.904442
CCL22 chemokine (C-C motif) ligand 22 0.889668
HSPG2 heparan sulfate proteoglycan 2 0.874919
CD4 CD4 molecule 0.827409
HARS histidyl-tRNA synthetase 0.80936
JCHAIN joining chain of multimeric IgA and IgM 0.789262
FOSL2 FOS-like antigen 2 0.787623
SFTPD surfactant protein D 0.786803
MMP7 matrix metallopeptidase 7 0.785165
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 0.76921
IFI44 interferon-induced protein 44 0.721673
TARS2 threonyl-tRNA synthetase 2, mitochondrial (putative) 0.714005
LRRC38 leucine rich repeat containing 38 0.704742
CXCR3 chemokine (C-X-C motif) receptor 3 0.675909
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) 0.664372
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha 0.654463
CXCL12 chemokine (C-X-C motif) ligand 12 0.629242
LTBP1 latent transforming growth factor beta binding protein 1 0.614747
CCL19 chemokine (C-C motif) ligand 19 0.614356
CCR7 chemokine (C-C motif) receptor 7 0.587444
FOXF1 forkhead box F1 0.585887
CXCL9 chemokine (C-X-C motif) ligand 9 0.553239
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa 0.548195
TMEM51 transmembrane protein 51 0.547807
TNC tenascin C 0.535796
CXCL10 chemokine (C-X-C motif) ligand 10 0.513033
TGFB1 transforming growth factor, beta 1 0.46466
EEA1 early endosome antigen 1 0.451454
CYCS cytochrome c, somatic 0.433021
PSMA7 proteasome (prosome, macropain) subunit, alpha type, 7 0.431894
CCL17 chemokine (C-C motif) ligand 17 0.412779
LGALS9 lectin, galactoside-binding, soluble, 9 0.40904
DEFB1 defensin, beta 1 0.406425
MMP2 matrix metallopeptidase 2 0.405678
KRT18 keratin 18, type I 0.404557
MPO myeloperoxidase 0.400826
TARS threonyl-tRNA synthetase 0.393746
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene) 0.391141
IL13 interleukin 13 0.384079
KLK15 kallikrein-related peptidase 15 0.384079
HPS1 Hermansky-Pudlak syndrome 1 0.38111
CCL13 chemokine (C-C motif) ligand 13 0.378514
CD151 CD151 molecule (Raph blood group) 0.377031
CD68 CD68 molecule 0.374809
CD34 CD34 molecule 0.370737
HBZ hemoglobin, zeta 0.358551
NT5C 5', 3'-nucleotidase, cytosolic 0.350084
CCL7 chemokine (C-C motif) ligand 7 0.333949
AQP5 aquaporin 5 0.328834
ASCL1 achaete-scute family bHLH transcription factor 1 0.301976
FBN2 fibrillin 2 0.289027
PGM1 phosphoglucomutase 1 0.28151
IL4 interleukin 4 0.270819
SHH sonic hedgehog 0.254183
CTGF connective tissue growth factor 0.246448
CXCL5 chemokine (C-X-C motif) ligand 5 0.240148
MMP9 matrix metallopeptidase 9 0.227642
CXCL11 chemokine (C-X-C motif) ligand 11 0.221793
IL4R interleukin 4 receptor 0.220424
IARS isoleucyl-tRNA synthetase 0.21974
WNT3A wingless-type MMTV integration site family, member 3A 0.207912
KEAP1 kelch-like ECH-associated protein 1 0.19582
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin) 0.192971
CCL21 chemokine (C-C motif) ligand 21 0.189551
STX2 syntaxin 2 0.189244
HBA2 hemoglobin, alpha 2 0.181222