nonmotile primary cilium Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A primary cilium which contains a variable array of axonemal microtubules but does not contain molecular motors. Nonmotile primary cilia are found on many different cell types and function as sensory organelles that concentrate and organize sensory signaling molecules. (Gene Ontology, GO_0031513)
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Genes

308 proteins co-occuring with the nonmotile primary cilium cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
RHO rhodopsin 2.11585
ABCA4 ATP-binding cassette, sub-family A (ABC1), member 4 1.89385
GUCY2D guanylate cyclase 2D, membrane (retina-specific) 1.72995
ROM1 retinal outer segment membrane protein 1 1.72369
RPGR retinitis pigmentosa GTPase regulator 1.71746
MERTK MER proto-oncogene, tyrosine kinase 1.69891
RPE65 retinal pigment epithelium-specific protein 65kDa 1.54178
RPGRIP1 retinitis pigmentosa GTPase regulator interacting protein 1 1.50566
GUCA1B guanylate cyclase activator 1B (retina) 1.47514
PRPH2 peripherin 2 (retinal degeneration, slow) 1.43951
PRCD progressive rod-cone degeneration 1.42317
PCDH15 protocadherin-related 15 1.37409
BEST1 bestrophin 1 1.27027
RCVRN recoverin 1.25548
RBP3 retinol binding protein 3, interstitial 1.22724
KIF17 kinesin family member 17 1.22464
MYO7A myosin VIIA 1.21273
GRK1 G protein-coupled receptor kinase 1 1.15825
RLBP1 retinaldehyde binding protein 1 1.15569
APOPT1 apoptogenic 1, mitochondrial 1.1342
CDH23 cadherin-related 23 1.12092
IFT57 intraflagellar transport 57 1.11786
GUCY2C guanylate cyclase 2C 1.09594
CFAP52 cilia and flagella associated protein 52 1.06903
NPR1 natriuretic peptide receptor 1 1.06044
LCA5 Leber congenital amaurosis 5 1.05488
CEP290 centrosomal protein 290kDa 1.03729
NPHP4 nephronophthisis 4 1.02829
IFT20 intraflagellar transport 20 1.01189
NRL neural retina leucine zipper 0.992204
PKD1L1 polycystic kidney disease 1 like 1 0.98927
IFT88 intraflagellar transport 88 0.985367
MAK male germ cell-associated kinase 0.978559
CRX cone-rod homeobox 0.978074
TMEM237 transmembrane protein 237 0.977104
B9D2 B9 protein domain 2 0.976619
RDH8 retinol dehydrogenase 8 (all-trans) 0.975166
B9D1 B9 protein domain 1 0.941162
KIF3A kinesin family member 3A 0.918579
PDE6G phosphodiesterase 6G, cGMP-specific, rod, gamma 0.916709
FRMD6 FERM domain containing 6 0.911579
IMPG2 interphotoreceptor matrix proteoglycan 2 0.890245
NPHP1 nephronophthisis 1 (juvenile) 0.886551
MKS1 Meckel syndrome, type 1 0.881477
DHDDS dehydrodolichyl diphosphate synthase 0.876869
PDE6H phosphodiesterase 6H, cGMP-specific, cone, gamma 0.863068
AIPL1 aryl hydrocarbon receptor interacting protein-like 1 0.852961
GALNT11 polypeptide N-acetylgalactosaminyltransferase 11 0.851124
GALNT16 polypeptide N-acetylgalactosaminyltransferase 16 0.851124
CNGB1 cyclic nucleotide gated channel beta 1 0.843778
CC2D2A coiled-coil and C2 domain containing 2A 0.841482
PDE6A phosphodiesterase 6A, cGMP-specific, rod, alpha 0.835974
SDR9C7 short chain dehydrogenase/reductase family 9C, member 7 0.818993
POC1B POC1 centriolar protein B 0.817616
IFT140 intraflagellar transport 140 0.81257
ANKMY2 ankyrin repeat and MYND domain containing 2 0.810735
CTSD cathepsin D 0.792854
ATP8A2 ATPase, aminophospholipid transporter, class I, type 8A, member 2 0.775928
RDH12 retinol dehydrogenase 12 (all-trans/9-cis/11-cis) 0.75453
FAM161A family with sequence similarity 161, member A 0.752716
GAS6 growth arrest-specific 6 0.746381
RGS9BP regulator of G protein signaling 9 binding protein 0.743671
MFGE8 milk fat globule-EGF factor 8 protein 0.740515
USH1C Usher syndrome 1C (autosomal recessive, severe) 0.727941
LRAT lecithin retinol acyltransferase (phosphatidylcholine--retinol O-acyltransferase) 0.713238
KIF3B kinesin family member 3B 0.705714
SDCCAG8 serologically defined colon cancer antigen 8 0.700863
INVS inversin 0.699103
IFT52 intraflagellar transport 52 0.698223
TCTN3 tectonic family member 3 0.696026
ELOVL4 ELOVL fatty acid elongase 4 0.692516
RP1 retinitis pigmentosa 1 (autosomal dominant) 0.69164
RP2 retinitis pigmentosa 2 (X-linked recessive) 0.683335
CERKL ceramide kinase-like 0.662072
KNCN kinocilin 0.66164
RFX1 regulatory factor X, 1 (influences HLA class II expression) 0.660776
SAG S-antigen; retina and pineal gland (arrestin) 0.650439
RP1L1 retinitis pigmentosa 1-like 1 0.636295
KIF3C kinesin family member 3C 0.633305
OPN1SW opsin 1 (cone pigments), short-wave-sensitive 0.626057
SUSD4 sushi domain containing 4 0.624355
TMEM231 transmembrane protein 231 0.62393
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta 0.619255
IFT80 intraflagellar transport 80 0.615861
TCTN1 tectonic family member 1 0.615861
ASMT acetylserotonin O-methyltransferase 0.615013
NCALD neurocalcin delta 0.613318
PKD1L2 polycystic kidney disease 1-like 2 (gene/pseudogene) 0.609932
SCARB1 scavenger receptor class B, member 1 0.608663
PDZD7 PDZ domain containing 7 0.59896
DYNC2LI1 dynein, cytoplasmic 2, light intermediate chain 1 0.595173
CEP162 centrosomal protein 162kDa 0.590133
UFSP2 UFM1-specific peptidase 2 0.585523
CNGB3 cyclic nucleotide gated channel beta 3 0.578833
CETN1 centrin, EF-hand protein, 1 0.576329
SPZ1 spermatogenic leucine zipper 1 0.575912
WDR19 WD repeat domain 19 0.575912
TTC26 tetratricopeptide repeat domain 26 0.571745
PTCHD3 patched domain containing 3 0.560528
ATP6V0D1 ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1 0.554732
AHI1 Abelson helper integration site 1 0.552664
OPN1LW opsin 1 (cone pigments), long-wave-sensitive 0.546885
DPCD deleted in primary ciliary dyskinesia homolog (mouse) 0.537827
SCARB2 scavenger receptor class B, member 2 0.531668
TCTN2 tectonic family member 2 0.523885
RPGRIP1L RPGRIP1-like 0.523067
PKD2L2 polycystic kidney disease 2-like 2 0.515716
ATP6V1F ATPase, H+ transporting, lysosomal 14kDa, V1 subunit F 0.515308
CDHR1 cadherin-related family member 1 0.512862
IFT22 intraflagellar transport 22 0.509604
CD36 CD36 molecule (thrombospondin receptor) 0.509197
RRH retinal pigment epithelium-derived rhodopsin homolog 0.503912
RD3 retinal degeneration 3 0.50107
ATP6V1E1 ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1 0.496205
PKD2L1 polycystic kidney disease 2-like 1 0.4865
ARL3 ADP-ribosylation factor-like 3 0.485693
FZD6 frizzled class receptor 6 0.478843
CNGA3 cyclic nucleotide gated channel alpha 3 0.476831
GUCA2A guanylate cyclase activator 2A (guanylin) 0.474822
TTC21B tetratricopeptide repeat domain 21B 0.47442
CFH complement factor H 0.474018
ANO2 anoctamin 2, calcium activated chloride channel 0.472011
FAM161B family with sequence similarity 161, member B 0.4672
CETN2 centrin, EF-hand protein, 2 0.466399
DFNB31 deafness, autosomal recessive 31 0.465998
RSPH9 radial spoke head 9 homolog (Chlamydomonas) 0.457606
PDC phosducin 0.456012
RAB8A RAB8A, member RAS oncogene family 0.442896
ARTN artemin 0.441708
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime 0.440124
IQCB1 IQ motif containing B1 0.428284
CHM choroideremia (Rab escort protein 1) 0.428284
TMEM67 transmembrane protein 67 0.421212
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1 0.42082
BBS2 Bardet-Biedl syndrome 2 0.414164
GNB5 guanine nucleotide binding protein (G protein), beta 5 0.411039
RGS9 regulator of G-protein signaling 9 0.407919
MATN3 matrilin 3 0.40714
MCHR2 melanin-concentrating hormone receptor 2 0.40714
NUBP1 nucleotide binding protein 1 0.40675
GUCA1A guanylate cyclase activator 1A (retina) 0.400139
THEMIS thymocyte selection associated 0.398975
FOXD2 forkhead box D2 0.392775
NUBP2 nucleotide binding protein 2 0.388137
CRB1 crumbs family member 1, photoreceptor morphogenesis associated 0.385051
USH2A Usher syndrome 2A (autosomal recessive, mild) 0.383895
STRCP1 stereocilin pseudogene 1 0.381969
STRC stereocilin 0.381969
ADGRV1 adhesion G protein-coupled receptor V1 0.378891
DNAAF1 dynein, axonemal, assembly factor 1 0.364713
ADAM9 ADAM metallopeptidase domain 9 0.361277
TMEM216 transmembrane protein 216 0.357467
OXR1 oxidation resistance 1 0.351762
TTLL6 tubulin tyrosine ligase-like family member 6 0.347587
KIZ kizuna centrosomal protein 0.345692
BBS4 Bardet-Biedl syndrome 4 0.345314
MREG melanoregulin 0.338884
NME7 NME/NM23 family member 7 0.337373
GLUL glutamate-ammonia ligase 0.330966
PKD2 polycystic kidney disease 2 (autosomal dominant) 0.329837
CSNK1E casein kinase 1, epsilon 0.328708
VANGL2 VANGL planar cell polarity protein 2 0.327956
CEP170 centrosomal protein 170kDa 0.327205
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A 0.326829
BEST2 bestrophin 2 0.323075
PRICKLE2 prickle homolog 2 (Drosophila) 0.3227
EVC2 Ellis van Creveld syndrome 2 0.318205
GNAT2 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2 0.313344
IFT27 intraflagellar transport 27 0.311478
ATP6V1H ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H 0.309613
S100B S100 calcium binding protein B 0.307377
PPP1R12A protein phosphatase 1, regulatory subunit 12A 0.307004
PARD6B par-6 family cell polarity regulator beta 0.30626
CEP131 centrosomal protein 131kDa 0.305515
FGF13 fibroblast growth factor 13 0.303283
TTL tubulin tyrosine ligase 0.303283
NCAN neurocan 0.301425
DVL2 dishevelled segment polarity protein 2 0.300311
IFT122 intraflagellar transport 122 0.300311
RTN2 reticulon 2 0.29623
AANAT aralkylamine N-acetyltransferase 0.295119
DCX doublecortin 0.292527
FGFRL1 fibroblast growth factor receptor-like 1 0.291787
UFM1 ubiquitin-fold modifier 1 0.289569
CRYBA1 crystallin, beta A1 0.282558
VEGFA vascular endothelial growth factor A 0.282189
S100A1 S100 calcium binding protein A1 0.280349
TRAF3IP1 TNF receptor-associated factor 3 interacting protein 1 0.27998
ITGA8 integrin, alpha 8 0.277406
MFRP membrane frizzled-related protein 0.277038
PRPF31 pre-mRNA processing factor 31 0.272633
USH1G Usher syndrome 1G (autosomal recessive) 0.272633
GFAP glial fibrillary acidic protein 0.271533
BBS7 Bardet-Biedl syndrome 7 0.271167
VIPR2 vasoactive intestinal peptide receptor 2 0.270434
TOPORS topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase 0.264946
PACRG PARK2 co-regulated 0.264946
RHOD ras homolog family member D 0.26239
CALM2 calmodulin 2 (phosphorylase kinase, delta) 0.259837
CALM3 calmodulin 3 (phosphorylase kinase, delta) 0.259837
CALM1 calmodulin 1 (phosphorylase kinase, delta) 0.259473
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1 0.258016
FGFR4 fibroblast growth factor receptor 4 0.256561
NINL ninein-like 0.254743
UNC119 unc-119 homolog (C. elegans) 0.251839
RDH5 retinol dehydrogenase 5 (11-cis/9-cis) 0.250026
CAD carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase 0.246769
FGF2 fibroblast growth factor 2 (basic) 0.245323
PKD1 polycystic kidney disease 1 (autosomal dominant) 0.242437
CYP26B1 cytochrome P450, family 26, subfamily B, polypeptide 1 0.241716
SHH sonic hedgehog 0.240276
GRB14 growth factor receptor-bound protein 14 0.238837
SSX2IP synovial sarcoma, X breakpoint 2 interacting protein 0.233817
GLI3 GLI family zinc finger 3 0.230245
SLC51A solute carrier family 51, alpha subunit 0.225622
EFHC1 EF-hand domain (C-terminal) containing 1 0.225267
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta 0.221378
C3 complement component 3 0.217861
MYO6 myosin VI 0.21716
SLC24A1 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1 0.21646
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) 0.21646
RBP1 retinol binding protein 1, cellular 0.21646
SLC16A8 solute carrier family 16 (monocarboxylate transporter), member 8 0.215412
PDE6D phosphodiesterase 6D, cGMP-specific, rod, delta 0.213669
COBL cordon-bleu WH2 repeat protein 0.213322
NUB1 negative regulator of ubiquitin-like proteins 1 0.21228
MAP1LC3A microtubule-associated protein 1 light chain 3 alpha 0.210549
RGS11 regulator of G-protein signaling 11 0.209858
TUBGCP4 tubulin, gamma complex associated protein 4 0.203361
MYO3A myosin IIIA 0.203361
GLI2 GLI family zinc finger 2 0.200328
TTC8 tetratricopeptide repeat domain 8 0.194045
RGS6 regulator of G-protein signaling 6 0.191777
MKKS McKusick-Kaufman syndrome 0.190814
FGFR2 fibroblast growth factor receptor 2 0.189222
PARD3 par-3 family cell polarity regulator 0.185469
ARR3 arrestin 3, retinal (X-arrestin) 0.182422
TADA3 transcriptional adaptor 3 0.180634
IFT172 intraflagellar transport 172 0.179752
RAB23 RAB23, member RAS oncogene family 0.179459
PKD1P6 polycystic kidney disease 1 (autosomal dominant) pseudogene 6 0.177439
FZD3 frizzled class receptor 3 0.176587
FTCD formimidoyltransferase cyclodeaminase 0.176587
MARCH7 membrane-associated ring finger (C3HC4) 7, E3 ubiquitin protein ligase 0.176305
IRF6 interferon regulatory factor 6 0.175745
PLA2G5 phospholipase A2, group V 0.173273
CLN3 ceroid-lipofuscinosis, neuronal 3 0.172468
FHL1 four and a half LIM domains 1 0.171937
FGFR1 fibroblast growth factor receptor 1 0.17141
INSR insulin receptor 0.159462
SPAG6 sperm associated antigen 6 0.158882
GORASP2 golgi reassembly stacking protein 2, 55kDa 0.158502
PPT1 palmitoyl-protein thioesterase 1 0.158315
BTNL2 butyrophilin-like 2 0.137401
PACSIN1 protein kinase C and casein kinase substrate in neurons 1 0.137311
MYO15A myosin XVA 0.137136
OFD1 oral-facial-digital syndrome 1 0.135757
EXOC5 exocyst complex component 5 0.135575
PROK2 prokineticin 2 0.135406
MACF1 microtubule-actin crosslinking factor 1 0.135166
GFI1 growth factor independent 1 transcription repressor 0.134946
MPP5 membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5) 0.134946
KCNJ3 potassium channel, inwardly rectifying subfamily J, member 3 0.134703
STX8 syntaxin 8 0.134694
SOX17 SRY (sex determining region Y)-box 17 0.134482
HES5 hes family bHLH transcription factor 5 0.133976
SIL1 SIL1 nucleotide exchange factor 0.133173
ATP2B2 ATPase, Ca++ transporting, plasma membrane 2 0.13272
DLG3 discs, large homolog 3 (Drosophila) 0.132223
DCTN2 dynactin 2 (p50) 0.132223
CA2 carbonic anhydrase II 0.132037
TRPA1 transient receptor potential cation channel, subfamily A, member 1 0.131654
AMD1 adenosylmethionine decarboxylase 1 0.130497
NUMB numb homolog (Drosophila) 0.129742
LIG3 ligase III, DNA, ATP-dependent 0.128855
EZR ezrin 0.128571
SMC3 structural maintenance of chromosomes 3 0.127723
EEF1A1P6 eukaryotic translation elongation factor 1 alpha 1 pseudogene 6 0.127462
OCLN occludin 0.127049
PVRL1 poliovirus receptor-related 1 (herpesvirus entry mediator C) 0.126734
GPR162 G protein-coupled receptor 162 0.126469
CETN3 centrin, EF-hand protein, 3 0.125366
ELANE elastase, neutrophil expressed 0.124981
AMPH amphiphysin 0.124872
ALB albumin 0.124806
SLC27A4 solute carrier family 27 (fatty acid transporter), member 4 0.124674
FGFR3 fibroblast growth factor receptor 3 0.124517
RAB18 RAB18, member RAS oncogene family 0.124358
ATP6V0C ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c 0.124244
PRPF3 pre-mRNA processing factor 3 0.124244
SPTBN2 spectrin, beta, non-erythrocytic 2 0.124244
CLIC4 chloride intracellular channel 4 0.124011
MMP8 matrix metallopeptidase 8 0.12387
BDNF brain-derived neurotrophic factor 0.123751
CERK ceramide kinase 0.123533
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 0.123533
RAB11B RAB11B, member RAS oncogene family 0.123509
HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) 0.12346
PRPF8 pre-mRNA processing factor 8 0.123312
FABP5 fatty acid binding protein 5 (psoriasis-associated) 0.122884
TEK TEK tyrosine kinase, endothelial 0.122859
DAND5 DAN domain family member 5, BMP antagonist 0.122729
ALS2 amyotrophic lateral sclerosis 2 (juvenile) 0.122677
HNRNPM heterogeneous nuclear ribonucleoprotein M 0.122388
NOTCH1 notch 1 0.122255
PROS1 protein S (alpha) 0.121678
SLC30A3 solute carrier family 30 (zinc transporter), member 3 0.12148
RGS7 regulator of G-protein signaling 7 0.12084