non-hodgkin lymphoma cell Gene Set

Dataset TISSUES Text-mining Tissue Protein Expression Evidence Scores
Category structural or functional annotations
Type tissue
Description A heterogeneous group of malignant lymphomas, the only common feature being an absence of the giant Reed-Sternberg cells characteristic of Hodgkin's disease. They arise from the lymphoid components of the immune system, and present a clinical picture broadly similar to that of Hodgkin's disease except the disease is initially more widespread, with the most common manifestation being painless enlargement of one or more peripheral lymph nodes. (BRENDA Tissue and Enzyme Source Ontology, BTO_0002846)
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Genes

317 proteins co-occuring with the tissue non-hodgkin lymphoma cell in abstracts of biomedical publications from the TISSUES Text-mining Tissue Protein Expression Evidence Scores dataset.

Symbol Name Standardized Value
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated) 1.21223
RASGRP3 RAS guanyl releasing protein 3 (calcium and DAG-regulated) 1.15407
AGPAT2 1-acylglycerol-3-phosphate O-acyltransferase 2 0.983688
METAP2 methionyl aminopeptidase 2 0.924623
BCL2L11 BCL2-like 11 (apoptosis facilitator) 0.902424
TNFSF8 tumor necrosis factor (ligand) superfamily, member 8 0.819412
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2 0.70968
ENDOG endonuclease G 0.703127
HDAC6 histone deacetylase 6 0.701489
TP53 tumor protein p53 0.701489
BCL6 B-cell CLL/lymphoma 6 0.666809
CTNND1 catenin (cadherin-associated protein), delta 1 0.60893
CD8B CD8b molecule 0.600479
ZHX2 zinc fingers and homeoboxes 2 0.58282
BIRC2 baculoviral IAP repeat containing 2 0.519253
BIRC3 baculoviral IAP repeat containing 3 0.466885
APAF1 apoptotic peptidase activating factor 1 0.463013
BCL2L1 BCL2-like 1 0.458759
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase 0.413532
BAX BCL2-associated X protein 0.405935
CASP3 caspase 3, apoptosis-related cysteine peptidase 0.393819
CASP8 caspase 8, apoptosis-related cysteine peptidase 0.38665
FOXO1 forkhead box O1 0.384766
CADM1 cell adhesion molecule 1 0.378372
AIFM1 apoptosis-inducing factor, mitochondrion-associated, 1 0.362273
CCND1 cyclin D1 0.316134
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 0.314046
SYK spleen tyrosine kinase 0.301039
ZNF280A zinc finger protein 280A 0.291677
PDPN podoplanin 0.287092
MYC v-myc avian myelocytomatosis viral oncogene homolog 0.259254
CASP9 caspase 9, apoptosis-related cysteine peptidase 0.242983
BTK Bruton agammaglobulinemia tyrosine kinase 0.241861
NANOG Nanog homeobox 0.233731
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) 0.218186
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.21356
SOX11 SRY (sex determining region Y)-box 11 0.208326
JADE3 jade family PHD finger 3 0.207756
HOXC12 homeobox C12 0.20724
GPR61 G protein-coupled receptor 61 0.203847
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 0.202055
PIK3IP1 phosphoinositide-3-kinase interacting protein 1 0.20063
SOX12 SRY (sex determining region Y)-box 12 0.200585
SREK1 splicing regulatory glutamine/lysine-rich protein 1 0.200547
RGS13 regulator of G-protein signaling 13 0.200334
MTOR mechanistic target of rapamycin (serine/threonine kinase) 0.200126
MOB3B MOB kinase activator 3B 0.19985
TBC1D9 TBC1 domain family, member 9 (with GRAM domain) 0.199653
SFMBT2 Scm-like with four mbt domains 2 0.199376
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 0.199155
CD5 CD5 molecule 0.19831
SETMAR SET domain and mariner transposase fusion gene 0.198266
HDGFRP3 hepatoma-derived growth factor, related protein 3 0.197727
KLRK1 killer cell lectin-like receptor subfamily K, member 1 0.1977
CD40LG CD40 ligand 0.197603
PHLPP2 PH domain and leucine rich repeat protein phosphatase 2 0.197514
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.197415
SUZ12 SUZ12 polycomb repressive complex 2 subunit 0.197182
ATM ATM serine/threonine kinase 0.196968
LYN LYN proto-oncogene, Src family tyrosine kinase 0.19675
HAVCR2 hepatitis A virus cellular receptor 2 0.196742
CD40 CD40 molecule, TNF receptor superfamily member 5 0.19669
CDK4 cyclin-dependent kinase 4 0.196587
TNFRSF13C tumor necrosis factor receptor superfamily, member 13C 0.196164
CD19 CD19 molecule 0.196082
GLIS2 GLIS family zinc finger 2 0.195973
KIR3DL3 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 3 0.194969
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) 0.194715
XPO1 exportin 1 0.194709
SGPL1 sphingosine-1-phosphate lyase 1 0.194706
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain 0.194623
ABCA6 ATP-binding cassette, sub-family A (ABC1), member 6 0.194393
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 0.194303
MAP3K14 mitogen-activated protein kinase kinase kinase 14 0.194216
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 0.194058
ROR1 receptor tyrosine kinase-like orphan receptor 1 0.193991
DLEU2L deleted in lymphocytic leukemia 2-like 0.193551
GLRA1 glycine receptor, alpha 1 0.193462
NCR1 natural cytotoxicity triggering receptor 1 0.193405
RALB v-ral simian leukemia viral oncogene homolog B 0.193401
MICA MHC class I polypeptide-related sequence A 0.193358
FASLG Fas ligand (TNF superfamily, member 6) 0.193106
CDK9 cyclin-dependent kinase 9 0.19308
BIK BCL2-interacting killer (apoptosis-inducing) 0.192952
LHX9 LIM homeobox 9 0.192907
CKS1B CDC28 protein kinase regulatory subunit 1B 0.1929
ABCE1 ATP-binding cassette, sub-family E (OABP), member 1 0.192685
CYFIP2 cytoplasmic FMR1 interacting protein 2 0.19265
HOXD10 homeobox D10 0.192611
NT5C2 5'-nucleotidase, cytosolic II 0.192001
PARP1 poly (ADP-ribose) polymerase 1 0.191901
IGKV1D-42 immunoglobulin kappa variable 1D-42 (non-functional) 0.19185
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.191846
GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) 0.19161
ERAP2 endoplasmic reticulum aminopeptidase 2 0.191523
EIF4E eukaryotic translation initiation factor 4E 0.191356
HOXA11 homeobox A11 0.191298
PRF1 perforin 1 (pore forming protein) 0.191008
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 0.190948
SEMG1 semenogelin I 0.190762
CERS6 ceramide synthase 6 0.190677
CCND2 cyclin D2 0.190677
MIR96 microRNA 96 0.190572
LOXL3 lysyl oxidase-like 3 0.190418
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9 0.190403
SOX4 SRY (sex determining region Y)-box 4 0.190345
IRF4 interferon regulatory factor 4 0.190325
NCAM1 neural cell adhesion molecule 1 0.190212
NGDN neuroguidin, EIF4E binding protein 0.190062
SMC1A structural maintenance of chromosomes 1A 0.189921
HOXD8 homeobox D8 0.18988
HLA-G major histocompatibility complex, class I, G 0.189834
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific) 0.189813
ANXA5 annexin A5 0.189813
GZMK granzyme K (granzyme 3; tryptase II) 0.189736
LOXL4 lysyl oxidase-like 4 0.18959
GDF1 growth differentiation factor 1 0.18958
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b 0.189569
CDK7 cyclin-dependent kinase 7 0.189485
PRMT5 protein arginine methyltransferase 5 0.189119
MLF1 myeloid leukemia factor 1 0.189047
CCND3 cyclin D3 0.189008
HDAC9 histone deacetylase 9 0.18892
CDK6 cyclin-dependent kinase 6 0.188903
RCC1 regulator of chromosome condensation 1 0.188881
GPX7 glutathione peroxidase 7 0.188864
SKP1 S-phase kinase-associated protein 1 0.18883
CDKN2A cyclin-dependent kinase inhibitor 2A 0.188717
NUGGC nuclear GTPase, germinal center associated 0.1887
STAT4 signal transducer and activator of transcription 4 0.188517
FAF1 Fas (TNFRSF6) associated factor 1 0.188032
HRK harakiri, BCL2 interacting protein 0.187776
ZNF804A zinc finger protein 804A 0.187658
HLA-C major histocompatibility complex, class I, C 0.187658
ATG3 autophagy related 3 0.187329
MAP6 microtubule-associated protein 6 0.187069
NEBL nebulette 0.186977
CD70 CD70 molecule 0.186877
HIST1H1D histone cluster 1, H1d 0.186682
RXRG retinoid X receptor, gamma 0.186462
IL2 interleukin 2 0.186372
HNRNPL heterogeneous nuclear ribonucleoprotein L 0.186266
AK5 adenylate kinase 5 0.18588
IL21 interleukin 21 0.18588
PRKDC protein kinase, DNA-activated, catalytic polypeptide 0.185836
MIR17 microRNA 17 0.185734
PTEN phosphatase and tensin homolog 0.185592
GDF7 growth differentiation factor 7 0.18557
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 0.18557
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like 0.185082
WHSC1 Wolf-Hirschhorn syndrome candidate 1 0.184539
ARHGAP32 Rho GTPase activating protein 32 0.184341
ATP5B ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide 0.184325
CD37 CD37 molecule 0.184183
BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2 0.184175
CIITA class II, major histocompatibility complex, transactivator 0.183807
YY1 YY1 transcription factor 0.183773
TEAD2 TEA domain family member 2 0.183764
SRC SRC proto-oncogene, non-receptor tyrosine kinase 0.183562
DUSP5 dual specificity phosphatase 5 0.183554
IMPDH2 IMP (inosine 5'-monophosphate) dehydrogenase 2 0.183518
ALOX5 arachidonate 5-lipoxygenase 0.183465
MDM4 MDM4, p53 regulator 0.183322
IL22RA1 interleukin 22 receptor, alpha 1 0.182656
AICDA activation-induced cytidine deaminase 0.182359
CDC37 cell division cycle 37 0.182232
BRCA2 breast cancer 2, early onset 0.181904
ING1 inhibitor of growth family, member 1 0.181874
CENPF centromere protein F, 350/400kDa 0.181629
KMT2B lysine (K)-specific methyltransferase 2B 0.181546
CCNH cyclin H 0.181442
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 0.181421
MAP4 microtubule-associated protein 4 0.18138
NR2F1 nuclear receptor subfamily 2, group F, member 1 0.180844
CXCR5 chemokine (C-X-C motif) receptor 5 0.180535
CD38 CD38 molecule 0.18049
ADSS adenylosuccinate synthase 0.180435
PTF1A pancreas specific transcription factor, 1a 0.180138
HOXB7 homeobox B7 0.180104
RB1 retinoblastoma 1 0.18008
FZD2 frizzled class receptor 2 0.179823
DVL2 dishevelled segment polarity protein 2 0.179657
ALDOC aldolase C, fructose-bisphosphate 0.179537
HIC1 hypermethylated in cancer 1 0.17922
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) 0.178896
BMI1 BMI1 proto-oncogene, polycomb ring finger 0.178858
UHRF1 ubiquitin-like with PHD and ring finger domains 1 0.178846
SDC2 syndecan 2 0.178564
CNR1 cannabinoid receptor 1 (brain) 0.178538
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit 0.1785
HRAS Harvey rat sarcoma viral oncogene homolog 0.178383
EN2 engrailed homeobox 2 0.178291
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1 0.177985
RING1 ring finger protein 1 0.177686
WNT3 wingless-type MMTV integration site family, member 3 0.177575
PIM2 Pim-2 proto-oncogene, serine/threonine kinase 0.177547
ATOH1 atonal homolog 1 (Drosophila) 0.177408
PIGF phosphatidylinositol glycan anchor biosynthesis, class F 0.177268
CD27 CD27 molecule 0.176896
MTAP methylthioadenosine phosphorylase 0.176749
SORL1 sortilin-related receptor, L(DLR class) A repeats containing 0.176182
CXCL13 chemokine (C-X-C motif) ligand 13 0.176031
WNT2 wingless-type MMTV integration site family member 2 0.175953
LOXL2 lysyl oxidase-like 2 0.175751
CD58 CD58 molecule 0.17572
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) 0.174751
TNF tumor necrosis factor 0.174634
CHEK2 checkpoint kinase 2 0.1746
SLC29A2 solute carrier family 29 (equilibrative nucleoside transporter), member 2 0.174481
PRAME preferentially expressed antigen in melanoma 0.174209
MCM8 minichromosome maintenance complex component 8 0.173895
SP100 SP100 nuclear antigen 0.173825
BCR breakpoint cluster region 0.173737
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 0.173665
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1 0.173629
HCN4 hyperpolarization activated cyclic nucleotide gated potassium channel 4 0.17345
RRM2 ribonucleotide reductase M2 0.173324
PCDH8 protocadherin 8 0.173141
SDC4 syndecan 4 0.173141
PEBP1 phosphatidylethanolamine binding protein 1 0.173011
RPS6 ribosomal protein S6 0.172993
EGR1 early growth response 1 0.172956
FOXC1 forkhead box C1 0.172845
HMGB2 high mobility group box 2 0.172485
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) 0.172447
HCN1 hyperpolarization activated cyclic nucleotide gated potassium channel 1 0.172179
RASA1 RAS p21 protein activator (GTPase activating protein) 1 0.172159
GJD2 gap junction protein, delta 2, 36kDa 0.171545
GRIA2 glutamate receptor, ionotropic, AMPA 2 0.170701
PAX7 paired box 7 0.169329
RALA v-ral simian leukemia viral oncogene homolog A (ras related) 0.168663
AQP5 aquaporin 5 0.168639
CD2AP CD2-associated protein 0.168615
GRIA4 glutamate receptor, ionotropic, AMPA 4 0.168188
HAVCR1 hepatitis A virus cellular receptor 1 0.168093
LYZ lysozyme 0.167361
RAG1 recombination activating gene 1 0.166907
CASQ1 calsequestrin 1 (fast-twitch, skeletal muscle) 0.165736
TCF3 transcription factor 3 0.165736
CD226 CD226 molecule 0.165574
CASQ2 calsequestrin 2 (cardiac muscle) 0.16552
EVPL envoplakin 0.163988
RAG2 recombination activating gene 2 0.163959
KIR2DL3 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3 0.163902
GNLY granulysin 0.163318
NOD1 nucleotide-binding oligomerization domain containing 1 0.162417
CASP7 caspase 7, apoptosis-related cysteine peptidase 0.161988
NCF2 neutrophil cytosolic factor 2 0.161863
HLA-E major histocompatibility complex, class I, E 0.159552
DIABLO diablo, IAP-binding mitochondrial protein 0.159552
CTRL chymotrypsin-like 0.159418
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 0.159384
NCOR2 nuclear receptor corepressor 2 0.158694
IRF6 interferon regulatory factor 6 0.157847
ICAM2 intercellular adhesion molecule 2 0.157811
IL13 interleukin 13 0.157089
BCL2 B-cell CLL/lymphoma 2 0.157052
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) 0.156792
CD80 CD80 molecule 0.156792
HPRT1 hypoxanthine phosphoribosyltransferase 1 0.156533
PAX6 paired box 6 0.156459
HLA-DRB4 major histocompatibility complex, class II, DR beta 4 0.156311
NLRP3 NLR family, pyrin domain containing 3 0.154106
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 0.151631
MGAT5 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase 0.151502
NCF1C neutrophil cytosolic factor 1C pseudogene 0.151459
CD24 CD24 molecule 0.150333
ICAM1 intercellular adhesion molecule 1 0.148492
CD86 CD86 molecule 0.148446
NCF1 neutrophil cytosolic factor 1 0.148173
KLRC1 killer cell lectin-like receptor subfamily C, member 1 0.147847
MIR183 microRNA 183 0.147378
CALM2 calmodulin 2 (phosphorylase kinase, delta) 0.147143
CALM3 calmodulin 3 (phosphorylase kinase, delta) 0.147143
TLR1 toll-like receptor 1 0.147143
TPX2 TPX2, microtubule-associated 0.14705
CALM1 calmodulin 1 (phosphorylase kinase, delta) 0.147003
CD22 CD22 molecule 0.146624
HDAC8 histone deacetylase 8 0.145269
ICAM3 intercellular adhesion molecule 3 0.144972
IL15 interleukin 15 0.143623
CD59 CD59 molecule, complement regulatory protein 0.143318
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase 0.143115
RBL2 retinoblastoma-like 2 0.140768
NOD2 nucleotide-binding oligomerization domain containing 2 0.139965
ACPP acid phosphatase, prostate 0.138984
MMP2 matrix metallopeptidase 2 0.138819
NCF4 neutrophil cytosolic factor 4, 40kDa 0.138655
PRDM1 PR domain containing 1, with ZNF domain 0.1367
LOXL1 lysyl oxidase-like 1 0.1367
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1 0.136183
ACVR1 activin A receptor, type I 0.135551
NOTCH1 notch 1 0.135436
LTB lymphotoxin beta (TNF superfamily, member 3) 0.135148
BIRC5 baculoviral IAP repeat containing 5 0.134268
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2 0.133974
HSPA4 heat shock 70kDa protein 4 0.133386
SMAD2 SMAD family member 2 0.132724
DBN1 drebrin 1 0.132303
NT5E 5'-nucleotidase, ecto (CD73) 0.132303
LONP1 lon peptidase 1, mitochondrial 0.131943
MKI67 marker of proliferation Ki-67 0.131333
MAP2 microtubule-associated protein 2 0.131272
FLOT1 flotillin 1 0.130596
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.130596
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 0.130228
TBX21 T-box 21 0.128602
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 0.128602
HOXA5 homeobox A5 0.128352
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila) 0.127842
UBR5 ubiquitin protein ligase E3 component n-recognin 5 0.127075
CAV1 caveolin 1, caveolae protein, 22kDa 0.126369
PYGB phosphorylase, glycogen; brain 0.126043
IGH immunoglobulin heavy locus 0.125848
PYGL phosphorylase, glycogen, liver 0.125848
PYGM phosphorylase, glycogen, muscle 0.125002
SEBOX SEBOX homeobox 0.124277