nomifensine-7217 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

194 genes differentially expressed following the nomifensine-7217 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAMDC adipogenesis associated, Mth938 domain containing
ACRV1 acrosomal vesicle protein 1
ADAM12 ADAM metallopeptidase domain 12
ADAMDEC1 ADAM-like, decysin 1
ADRB1 adrenoceptor beta 1
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
ATF7IP activating transcription factor 7 interacting protein
BAIAP2 BAI1-associated protein 2
BCL2L10 BCL2-like 10 (apoptosis facilitator)
BGN biglycan
BTF3P11 basic transcription factor 3 pseudogene 11
CA5BP1 carbonic anhydrase VB pseudogene 1
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CACNB4 calcium channel, voltage-dependent, beta 4 subunit
CALB2 calbindin 2
CCHCR1 coiled-coil alpha-helical rod protein 1
CD52 CD52 molecule
CDH15 cadherin 15, type 1, M-cadherin (myotubule)
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2
COL5A2 collagen, type V, alpha 2
COPZ2 coatomer protein complex, subunit zeta 2
CR1 complement component (3b/4b) receptor 1 (Knops blood group)
CRIP1 cysteine-rich protein 1 (intestinal)
CYP3A43 cytochrome P450, family 3, subfamily A, polypeptide 43
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
DHX34 DEAH (Asp-Glu-Ala-His) box polypeptide 34
DIMT1 DIM1 dimethyladenosine transferase 1 homolog (S. cerevisiae)
DLC1 DLC1 Rho GTPase activating protein
DNASE1L3 deoxyribonuclease I-like 3
DOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1)
DOK4 docking protein 4
DUSP26 dual specificity phosphatase 26 (putative)
DYSF dysferlin
EXOG endo/exonuclease (5'-3'), endonuclease G-like
FAM182B family with sequence similarity 182, member B
GNAS GNAS complex locus
GSTA3 glutathione S-transferase alpha 3
GSTCD glutathione S-transferase, C-terminal domain containing
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HR hair growth associated
IFI6 interferon, alpha-inducible protein 6
IFITM1 interferon induced transmembrane protein 1
IFT122 intraflagellar transport 122
IQCK IQ motif containing K
KDM4B lysine (K)-specific demethylase 4B
KDM5C lysine (K)-specific demethylase 5C
KIAA1109 KIAA1109
KIDINS220 kinase D-interacting substrate, 220kDa
KLRAP1 killer cell lectin-like receptor subfamily A pseudogene 1
L3MBTL1 l(3)mbt-like 1 (Drosophila)
LIME1 Lck interacting transmembrane adaptor 1
LLGL1 lethal giant larvae homolog 1 (Drosophila)
LLPH LLP homolog, long-term synaptic facilitation (Aplysia)
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
LTC4S leukotriene C4 synthase
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1
MAOA monoamine oxidase A
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MTSS1L metastasis suppressor 1-like
MYRIP myosin VIIA and Rab interacting protein
NOX5 NADPH oxidase, EF-hand calcium binding domain 5
NPAS3 neuronal PAS domain protein 3
NPHS2 nephrosis 2, idiopathic, steroid-resistant (podocin)
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
OPCML opioid binding protein/cell adhesion molecule-like
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
PAPOLA poly(A) polymerase alpha
PAX5 paired box 5
PLK4 polo-like kinase 4
PPP1R14D protein phosphatase 1, regulatory (inhibitor) subunit 14D
PRAME preferentially expressed antigen in melanoma
PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta
PRX periaxin
R3HDM1 R3H domain containing 1
RANBP3 RAN binding protein 3
RIC3 RIC3 acetylcholine receptor chaperone
RPS14 ribosomal protein S14
RPS3A ribosomal protein S3A
SCGB2A2 secretoglobin, family 2A, member 2
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SFRP1 secreted frizzled-related protein 1
SIGLEC6 sialic acid binding Ig-like lectin 6
SLA Src-like-adaptor
SLC19A1 solute carrier family 19 (folate transporter), member 1
SLC22A14 solute carrier family 22, member 14
SPAG8 sperm associated antigen 8
SPHK2 sphingosine kinase 2
SVEP1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
SYBU syntabulin (syntaxin-interacting)
TAT tyrosine aminotransferase
TPD52 tumor protein D52
UBOX5 U-box domain containing 5
VWA5A von Willebrand factor A domain containing 5A
XYLB xylulokinase homolog (H. influenzae)
YOD1 YOD1 deubiquitinase

decreased expression

Symbol Name
AARSD1 alanyl-tRNA synthetase domain containing 1
ABHD14A abhydrolase domain containing 14A
AHR aryl hydrocarbon receptor
ALKBH4 alkB, alkylation repair homolog 4 (E. coli)
ANKS1A ankyrin repeat and sterile alpha motif domain containing 1A
ARFGAP1 ADP-ribosylation factor GTPase activating protein 1
ASPHD1 aspartate beta-hydroxylase domain containing 1
ATP7B ATPase, Cu++ transporting, beta polypeptide
AXIN1 axin 1
AZI2 5-azacytidine induced 2
BAK1 BCL2-antagonist/killer 1
BRAF B-Raf proto-oncogene, serine/threonine kinase
C10ORF88 chromosome 10 open reading frame 88
C17ORF75 chromosome 17 open reading frame 75
C22ORF29 chromosome 22 open reading frame 29
C9ORF40 chromosome 9 open reading frame 40
CAPG capping protein (actin filament), gelsolin-like
CEP72 centrosomal protein 72kDa
CLDN15 claudin 15
CLSPN claspin
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4
COBL cordon-bleu WH2 repeat protein
CTNNBL1 catenin, beta like 1
DEAF1 DEAF1 transcription factor
DUSP8 dual specificity phosphatase 8
EPPK1 epiplakin 1
FAM188A family with sequence similarity 188, member A
FANCF Fanconi anemia, complementation group F
FOXRED2 FAD-dependent oxidoreductase domain containing 2
GATA6 GATA binding protein 6
GLS2 glutaminase 2 (liver, mitochondrial)
GNE glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
GUSBP3 glucuronidase, beta pseudogene 3
KAT2A K(lysine) acetyltransferase 2A
KREMEN2 kringle containing transmembrane protein 2
LOC642236 FSHD region gene 1 pseudogene
LRFN3 leucine rich repeat and fibronectin type III domain containing 3
LRFN4 leucine rich repeat and fibronectin type III domain containing 4
LRRC20 leucine rich repeat containing 20
LRRC8E leucine rich repeat containing 8 family, member E
MANBA mannosidase, beta A, lysosomal
MANEA mannosidase, endo-alpha
MAP7D1 MAP7 domain containing 1
MKLN1 muskelin 1, intracellular mediator containing kelch motifs
MMP15 matrix metallopeptidase 15 (membrane-inserted)
MOSPD3 motile sperm domain containing 3
MXD3 MAX dimerization protein 3
MYO1D myosin ID
MYO1E myosin IE
NDE1 nudE neurodevelopment protein 1
NDUFAF7 NADH dehydrogenase (ubiquinone) complex I, assembly factor 7
NKAIN1 Na+/K+ transporting ATPase interacting 1
PELI1 pellino E3 ubiquitin protein ligase 1
PLA2G15 phospholipase A2, group XV
PLD2 phospholipase D2
POLH polymerase (DNA directed), eta
PTBP2 polypyrimidine tract binding protein 2
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)
PTPN9 protein tyrosine phosphatase, non-receptor type 9
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
ROM1 retinal outer segment membrane protein 1
RP2 retinitis pigmentosa 2 (X-linked recessive)
RPAP2 RNA polymerase II associated protein 2
RPL13P5 ribosomal protein L13 pseudogene 5
RRP9 ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast)
SHARPIN SHANK-associated RH domain interactor
SIK1 salt-inducible kinase 1
SLC25A28 solute carrier family 25 (mitochondrial iron transporter), member 28
SLC26A6 solute carrier family 26 (anion exchanger), member 6
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SNHG3 small nucleolar RNA host gene 3
SPAG1 sperm associated antigen 1
STBD1 starch binding domain 1
SYNGR3 synaptogyrin 3
SYNJ2BP synaptojanin 2 binding protein
SYT17 synaptotagmin XVII
THNSL1 threonine synthase-like 1 (S. cerevisiae)
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TMOD3 tropomodulin 3 (ubiquitous)
TRAPPC2 trafficking protein particle complex 2
TSPAN1 tetraspanin 1
TTC23 tetratricopeptide repeat domain 23
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
VPS37B vacuolar protein sorting 37 homolog B (S. cerevisiae)
VWA1 von Willebrand factor A domain containing 1
WDR19 WD repeat domain 19
XYLT2 xylosyltransferase II
YBX2 Y box binding protein 2
ZBTB6 zinc finger and BTB domain containing 6
ZDHHC13 zinc finger, DHHC-type containing 13
ZKSCAN3 zinc finger with KRAB and SCAN domains 3
ZMAT5 zinc finger, matrin-type 5
ZNF322P1 zinc finger protein 322 pseudogene 1
ZNF573 zinc finger protein 573
ZNHIT2 zinc finger, HIT-type containing 2