nomifensine-2062 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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198 genes differentially expressed following the nomifensine-2062 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ABI3BP ABI family, member 3 (NESH) binding protein
AK1 adenylate kinase 1
ANXA10 annexin A10
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12
AURKA aurora kinase A
BMP4 bone morphogenetic protein 4
BMP6 bone morphogenetic protein 6
BTG2 BTG family, member 2
C11ORF30 chromosome 11 open reading frame 30
C11ORF63 chromosome 11 open reading frame 63
C1R complement component 1, r subcomponent
C2CD2L C2CD2-like
C9ORF116 chromosome 9 open reading frame 116
CCL20 chemokine (C-C motif) ligand 20
CDH7 cadherin 7, type 2
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1
CENPJ centromere protein J
CHCHD7 coiled-coil-helix-coiled-coil-helix domain containing 7
CNTNAP2 contactin associated protein-like 2
CPED1 cadherin-like and PC-esterase domain containing 1
CREM cAMP responsive element modulator
CST1 cystatin SN
CTIF CBP80/20-dependent translation initiation factor
DMBT1 deleted in malignant brain tumors 1
DOHH deoxyhypusine hydroxylase/monooxygenase
EPHB2 EPH receptor B2
EPHX2 epoxide hydrolase 2, cytoplasmic
EPS8L1 EPS8-like 1
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
ETV5 ets variant 5
EXOC6B exocyst complex component 6B
FBXO2 F-box protein 2
FCMR Fc fragment of IgM receptor
FGF1 fibroblast growth factor 1 (acidic)
FOXA2 forkhead box A2
FPGS folylpolyglutamate synthase
FSD1 fibronectin type III and SPRY domain containing 1
GAL3ST4 galactose-3-O-sulfotransferase 4
GAPDHS glyceraldehyde-3-phosphate dehydrogenase, spermatogenic
GDPD3 glycerophosphodiester phosphodiesterase domain containing 3
GGA2 golgi-associated, gamma adaptin ear containing, ARF binding protein 2
GLS2 glutaminase 2 (liver, mitochondrial)
GPR137 G protein-coupled receptor 137
HOOK1 hook microtubule-tethering protein 1
IFT122 intraflagellar transport 122
IRF5 interferon regulatory factor 5
KIAA0930 KIAA0930
KPNA1 karyopherin alpha 1 (importin alpha 5)
LOC730101 uncharacterized LOC730101
LRRC15 leucine rich repeat containing 15
LRRC61 leucine rich repeat containing 61
MBNL2 muscleblind-like splicing regulator 2
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MED28 mediator complex subunit 28
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
MTSS1L metastasis suppressor 1-like
MUC1 mucin 1, cell surface associated
MYCL v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog
NADK NAD kinase
NEBL nebulette
NMT2 N-myristoyltransferase 2
NPRL2 nitrogen permease regulator-like 2 (S. cerevisiae)
NR4A2 nuclear receptor subfamily 4, group A, member 2
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa
PACS1 phosphofurin acidic cluster sorting protein 1
PECAM1 platelet/endothelial cell adhesion molecule 1
PER3 period circadian clock 3
PHF20L1 PHD finger protein 20-like 1
PI4K2A phosphatidylinositol 4-kinase type 2 alpha
PLAG1 pleiomorphic adenoma gene 1
PLXNA2 plexin A2
PRDM2 PR domain containing 2, with ZNF domain
PRKRIP1 PRKR interacting protein 1 (IL11 inducible)
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5
RIN1 Ras and Rab interactor 1
RPL14 ribosomal protein L14
RPS11 ribosomal protein S11
SAA3P serum amyloid A3 pseudogene
SENP6 SUMO1/sentrin specific peptidase 6
SLC39A9 solute carrier family 39, member 9
SLC6A20 solute carrier family 6 (proline IMINO transporter), member 20
SOD3 superoxide dismutase 3, extracellular
SP100 SP100 nuclear antigen
SUGP1 SURP and G patch domain containing 1
TAF9B TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa
TIMM17A translocase of inner mitochondrial membrane 17 homolog A (yeast)
TMEM159 transmembrane protein 159
TMEM231 transmembrane protein 231
TROVE2 TROVE domain family, member 2
TSPAN8 tetraspanin 8
TSPAN9 tetraspanin 9
UBQLN4 ubiquilin 4
WDR1 WD repeat domain 1
WIPF1 WAS/WASL interacting protein family, member 1
ZC2HC1C zinc finger, C2HC-type containing 1C
ZNF230 zinc finger protein 230

decreased expression

Symbol Name
ADPRM ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent
AMT aminomethyltransferase
ANAPC2 anaphase promoting complex subunit 2
ANKRD36B ankyrin repeat domain 36B
ANOS1 anosmin 1
APOL6 apolipoprotein L, 6
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
ATP10D ATPase, class V, type 10D
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
B4GALT2 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
BCAS4 breast carcinoma amplified sequence 4
BDH1 3-hydroxybutyrate dehydrogenase, type 1
C16ORF59 chromosome 16 open reading frame 59
C19ORF40 chromosome 19 open reading frame 40
CAMK1 calcium/calmodulin-dependent protein kinase I
CBX7 chromobox homolog 7
CCDC176 coiled-coil domain containing 176
CDK5 cyclin-dependent kinase 5
CENPQ centromere protein Q
CHMP6 charged multivesicular body protein 6
CHPF chondroitin polymerizing factor
CLASP1 cytoplasmic linker associated protein 1
CLDN1 claudin 1
CLDN15 claudin 15
DBR1 debranching RNA lariats 1
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta
EHF ets homologous factor
EMD emerin
EVPL envoplakin
FRAT1 frequently rearranged in advanced T-cell lymphomas 1
HCG4 HLA complex group 4 (non-protein coding)
HDAC7 histone deacetylase 7
HDHD3 haloacid dehalogenase-like hydrolase domain containing 3
HMGB3P1 high mobility group box 3 pseudogene 1
HOXB13 homeobox B13
HSPA4L heat shock 70kDa protein 4-like
IFT22 intraflagellar transport 22
IL15RA interleukin 15 receptor, alpha
IRF1 interferon regulatory factor 1
KCNMB3 potassium channel subfamily M regulatory beta subunit 3
KDM5C lysine (K)-specific demethylase 5C
KIAA1549L KIAA1549-like
KLC2 kinesin light chain 2
KRT4 keratin 4, type II
KRT8P12 keratin 8 pseudogene 12
LIG4 ligase IV, DNA, ATP-dependent
LOC100127972 uncharacterized LOC100127972
MAFG v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G
ME3 malic enzyme 3, NADP(+)-dependent, mitochondrial
MGMT O-6-methylguanine-DNA methyltransferase
MIS18BP1 MIS18 binding protein 1
MITF microphthalmia-associated transcription factor
MPDU1 mannose-P-dolichol utilization defect 1
MXD3 MAX dimerization protein 3
NME6 NME/NM23 nucleoside diphosphate kinase 6
OCEL1 occludin/ELL domain containing 1
ODF2 outer dense fiber of sperm tails 2
PARP3 poly (ADP-ribose) polymerase family, member 3
PGGT1B protein geranylgeranyltransferase type I, beta subunit
PGS1 phosphatidylglycerophosphate synthase 1
PLCD1 phospholipase C, delta 1
PLEKHA1 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
PLEKHA6 pleckstrin homology domain containing, family A member 6
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
RUNX1-IT1 RUNX1 intronic transcript 1
SCML2 sex comb on midleg-like 2 (Drosophila)
SCYL2 SCY1-like 2 (S. cerevisiae)
SEC14L2 SEC14-like 2 (S. cerevisiae)
SETD6 SET domain containing 6
SHPK sedoheptulokinase
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1
SNPH syntaphilin
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1
SREK1IP1 SREK1-interacting protein 1
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
SYNJ2BP synaptojanin 2 binding protein
SYTL2 synaptotagmin-like 2
TBX19 T-box 19
TM7SF2 transmembrane 7 superfamily member 2
TMOD3 tropomodulin 3 (ubiquitous)
TOE1 target of EGR1, member 1 (nuclear)
TRAPPC6A trafficking protein particle complex 6A
TTBK2 tau tubulin kinase 2
TTC17 tetratricopeptide repeat domain 17
UNC119 unc-119 homolog (C. elegans)
UNKL unkempt family zinc finger-like
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
USP6NL USP6 N-terminal like
WDR76 WD repeat domain 76
ZKSCAN3 zinc finger with KRAB and SCAN domains 3
ZNF124 zinc finger protein 124
ZNF175 zinc finger protein 175
ZNF273 zinc finger protein 273
ZNF324 zinc finger protein 324
ZNF354A zinc finger protein 354A
ZNF551 zinc finger protein 551
ZNF562 zinc finger protein 562
ZNF665 zinc finger protein 665
ZNF862 zinc finger protein 862