nodular malignant melanoma Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description A melanoma that is characterized as highly aggressive and manifests as a uniform blue-black, blue-red, or amelanotic nodule. (Human Disease Ontology, DOID_10047)
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Genes

69 genes co-occuring with the disease nodular malignant melanoma in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
NMS neuromedin S 1.99549
SEC23IP SEC23 interacting protein 1.27868
G3BP2 GTPase activating protein (SH3 domain) binding protein 2 1.16392
ABCB5 ATP-binding cassette, sub-family B (MDR/TAP), member 5 1.11099
IFNA8 interferon, alpha 8 1.02397
FGFR1OP FGFR1 oncogene partner 0.946186
DIS3 DIS3 exosome endoribonuclease and 3'-5' exoribonuclease 0.93497
EFNA1 ephrin-A1 0.870825
MTAP methylthioadenosine phosphorylase 0.806488
USO1 USO1 vesicle transport factor 0.800744
ALDH7A1 aldehyde dehydrogenase 7 family, member A1 0.793361
MCM4 minichromosome maintenance complex component 4 0.767576
XPR1 xenotropic and polytropic retrovirus receptor 1 0.689893
MIR191 microRNA 191 0.670333
TPD52 tumor protein D52 0.66199
HRAS Harvey rat sarcoma viral oncogene homolog 0.636315
MMP16 matrix metallopeptidase 16 (membrane-inserted) 0.621008
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) 0.60342
CENPF centromere protein F, 350/400kDa 0.59913
NES nestin 0.592506
NLRP1 NLR family, pyrin domain containing 1 0.577716
BRAF B-Raf proto-oncogene, serine/threonine kinase 0.549359
TYR tyrosinase 0.532701
KRT15 keratin 15, type I 0.491215
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog 0.488169
MIB1 mindbomb E3 ubiquitin protein ligase 1 0.47753
CDKN2A cyclin-dependent kinase inhibitor 2A 0.475255
PROM1 prominin 1 0.473361
DMBT1 deleted in malignant brain tumors 1 0.470711
KIR2DL3 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3 0.465794
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) 0.457487
CDH3 cadherin 3, type 1, P-cadherin (placental) 0.443923
KRAS Kirsten rat sarcoma viral oncogene homolog 0.441666
PTTG1 pituitary tumor-transforming 1 0.438282
CASP6 caspase 6, apoptosis-related cysteine peptidase 0.419892
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent) 0.410909
IFNB1 interferon, beta 1, fibroblast 0.402692
TP53 tumor protein p53 0.396725
KIR2DL1 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1 0.396353
GNAQ guanine nucleotide binding protein (G protein), q polypeptide 0.387794
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) 0.384822
MCOLN1 mucolipin 1 0.372587
JUP junction plakoglobin 0.368149
ITGA6 integrin, alpha 6 0.360764
ZNF135 zinc finger protein 135 0.357077
FGFR4 fibroblast growth factor receptor 4 0.344574
PDPN podoplanin 0.342739
MITF microphthalmia-associated transcription factor 0.307033
DSG3 desmoglein 3 0.297651
DSG1 desmoglein 1 0.296931
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) 0.295851
ICAM1 intercellular adhesion molecule 1 0.287593
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein 0.282582
C1QBP complement component 1, q subcomponent binding protein 0.27794
LYVE1 lymphatic vessel endothelial hyaluronan receptor 1 0.270464
EPHA2 EPH receptor A2 0.261952
DES desmin 0.260538
IRF4 interferon regulatory factor 4 0.260184
APAF1 apoptotic peptidase activating factor 1 0.25983
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) 0.248203
MCAM melanoma cell adhesion molecule 0.230409
CCND3 cyclin D3 0.204923
MLANA melan-A 0.202946
NLRP3 NLR family, pyrin domain containing 3 0.180937
CCND1 cyclin D1 0.176215
KITLG KIT ligand 0.173314
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog 0.163729
CDC42 cell division cycle 42 0.160948
FGF2 fibroblast growth factor 2 (basic) 0.158605