nocodazole-7145 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the nocodazole-7145 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
ABI2 abl-interactor 2
ACACA acetyl-CoA carboxylase alpha
ADM adrenomedullin
AMOTL2 angiomotin like 2
APC adenomatous polyposis coli
ARAP2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
ARMC8 armadillo repeat containing 8
ARTN artemin
BHLHB9 basic helix-loop-helix domain containing, class B, 9
BRF1 BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit
C1ORF116 chromosome 1 open reading frame 116
C7ORF43 chromosome 7 open reading frame 43
CALML4 calmodulin-like 4
CDKL3 cyclin-dependent kinase-like 3
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CENPJ centromere protein J
CEP295 centrosomal protein 295kDa
CEP72 centrosomal protein 72kDa
CLN8 ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation)
CNNM3 cyclin and CBS domain divalent metal cation transport mediator 3
CTGF connective tissue growth factor
CYR61 cysteine-rich, angiogenic inducer, 61
DIEXF digestive organ expansion factor homolog (zebrafish)
DUSP1 dual specificity phosphatase 1
EIF2S2 eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
FAM110B family with sequence similarity 110, member B
FGFR4 fibroblast growth factor receptor 4
FLT3LG fms-related tyrosine kinase 3 ligand
FST follistatin
FURIN furin (paired basic amino acid cleaving enzyme)
GADD45B growth arrest and DNA-damage-inducible, beta
GPRC5A G protein-coupled receptor, class C, group 5, member A
GPX2 glutathione peroxidase 2
HBEGF heparin-binding EGF-like growth factor
IGHD immunoglobulin heavy constant delta
IL24 interleukin 24
IL7 interleukin 7
INO80B INO80 complex subunit B
INS insulin
KLF2 Kruppel-like factor 2
KRT33A keratin 33A, type I
KRT34 keratin 34, type I
LGR5 leucine-rich repeat containing G protein-coupled receptor 5
LMO7 LIM domain 7
LSM4 LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae)
MAPK7 mitogen-activated protein kinase 7
MAPT microtubule-associated protein tau
MPPE1 metallophosphoesterase 1
MSL3 male-specific lethal 3 homolog (Drosophila)
NDE1 nudE neurodevelopment protein 1
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
NGF nerve growth factor (beta polypeptide)
NOTCH1 notch 1
NPFFR1 neuropeptide FF receptor 1
NRXN3 neurexin 3
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
OSBPL2 oxysterol binding protein-like 2
OSBPL3 oxysterol binding protein-like 3
PAX2 paired box 2
PDGFA platelet-derived growth factor alpha polypeptide
PDLIM5 PDZ and LIM domain 5
PHKG2 phosphorylase kinase, gamma 2 (testis)
PLAG1 pleiomorphic adenoma gene 1
PLK4 polo-like kinase 4
PPP1R13L protein phosphatase 1, regulatory subunit 13 like
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
PRND prion protein 2 (dublet)
PRR7 proline rich 7 (synaptic)
PSMD9 proteasome (prosome, macropain) 26S subunit, non-ATPase, 9
RAD54L RAD54-like (S. cerevisiae)
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RCE1 Ras converting CAAX endopeptidase 1
RSPH14 radial spoke head 14 homolog (Chlamydomonas)
RUNX3 runt-related transcription factor 3
RUSC2 RUN and SH3 domain containing 2
SAP18 Sin3A-associated protein, 18kDa
SLC22A17 solute carrier family 22, member 17
SLC29A2 solute carrier family 29 (equilibrative nucleoside transporter), member 2
SMC4 structural maintenance of chromosomes 4
SMG7 SMG7 nonsense mediated mRNA decay factor
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SNAPC1 small nuclear RNA activating complex, polypeptide 1, 43kDa
SNORA21 small nucleolar RNA, H/ACA box 21
SNRPN small nuclear ribonucleoprotein polypeptide N
SPN sialophorin
SUGP1 SURP and G patch domain containing 1
TGFB2 transforming growth factor, beta 2
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TOP3A topoisomerase (DNA) III alpha
TPRA1 transmembrane protein, adipocyte asscociated 1
TRMT61A tRNA methyltransferase 61A
VPS13D vacuolar protein sorting 13 homolog D (S. cerevisiae)
WDR1 WD repeat domain 1
WDR59 WD repeat domain 59
WT1 Wilms tumor 1
ZFHX3 zinc finger homeobox 3
ZNF202 zinc finger protein 202
ZNF688 zinc finger protein 688

decreased expression

Symbol Name
ABHD17B abhydrolase domain containing 17B
ABLIM3 actin binding LIM protein family, member 3
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
AP1G2 adaptor-related protein complex 1, gamma 2 subunit
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
BAK1 BCL2-antagonist/killer 1
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
BCL2L2 BCL2-like 2
CAND2 cullin-associated and neddylation-dissociated 2 (putative)
CDC37L1 cell division cycle 37-like 1
CEP131 centrosomal protein 131kDa
CEP290 centrosomal protein 290kDa
CEP70 centrosomal protein 70kDa
CIR1 corepressor interacting with RBPJ, 1
DAAM1 dishevelled associated activator of morphogenesis 1
DENND1B DENN/MADD domain containing 1B
DYSF dysferlin
ERCC5 excision repair cross-complementation group 5
FBXO3 F-box protein 3
FGD1 FYVE, RhoGEF and PH domain containing 1
FLRT3 fibronectin leucine rich transmembrane protein 3
FZD8 frizzled class receptor 8
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
GLCE glucuronic acid epimerase
HAS2 hyaluronan synthase 2
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
HIST2H2BE histone cluster 2, H2be
HOXA10 homeobox A10
IFT46 intraflagellar transport 46
ITPKB inositol-trisphosphate 3-kinase B
KIAA0513 KIAA0513
KIAA0753 KIAA0753
KIAA1462 KIAA1462
KIAA1549L KIAA1549-like
KLHL12 kelch-like family member 12
KLHL3 kelch-like family member 3
KRT15 keratin 15, type I
LHFPL2 lipoma HMGIC fusion partner-like 2
MAP9 microtubule-associated protein 9
MBTD1 mbt domain containing 1
MMP1 matrix metallopeptidase 1
MUL1 mitochondrial E3 ubiquitin protein ligase 1
NBEA neurobeachin
NECAP2 NECAP endocytosis associated 2
NOV nephroblastoma overexpressed
NPDC1 neural proliferation, differentiation and control, 1
PALB2 partner and localizer of BRCA2
PCSK7 proprotein convertase subtilisin/kexin type 7
PEX26 peroxisomal biogenesis factor 26
PI4KA phosphatidylinositol 4-kinase, catalytic, alpha
PID1 phosphotyrosine interaction domain containing 1
POLR3D polymerase (RNA) III (DNA directed) polypeptide D, 44kDa
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa
RAB20 RAB20, member RAS oncogene family
RAB3A RAB3A, member RAS oncogene family
RBM4B RNA binding motif protein 4B
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
REPS2 RALBP1 associated Eps domain containing 2
RFXANK regulatory factor X-associated ankyrin-containing protein
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RHOBTB1 Rho-related BTB domain containing 1
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SETD8 SET domain containing (lysine methyltransferase) 8
SIPA1 signal-induced proliferation-associated 1
SIX1 SIX homeobox 1
SPATA7 spermatogenesis associated 7
SSBP2 single-stranded DNA binding protein 2
SYTL2 synaptotagmin-like 2
TAF13 TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa
TAGLN3 transgelin 3
TBL3 transducin (beta)-like 3
TDRD7 tudor domain containing 7
TENM4 teneurin transmembrane protein 4
TGFBRAP1 transforming growth factor, beta receptor associated protein 1
THAP10 THAP domain containing 10
TM7SF2 transmembrane 7 superfamily member 2
TMEM242 transmembrane protein 242
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TRAPPC6A trafficking protein particle complex 6A
TRIM9 tripartite motif containing 9
TTBK2 tau tubulin kinase 2
TUBA1A tubulin, alpha 1a
TUBA3D tubulin, alpha 3d
TUBA4A tubulin, alpha 4a
TUBB tubulin, beta class I
TUBB2A tubulin, beta 2A class IIa
TUBB3 tubulin, beta 3 class III
TUBB4B tubulin, beta 4B class IVb
UBTD1 ubiquitin domain containing 1
USP6 ubiquitin specific peptidase 6
USP6NL USP6 N-terminal like
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
ZDHHC11 zinc finger, DHHC-type containing 11
ZKSCAN3 zinc finger with KRAB and SCAN domains 3
ZNF33B zinc finger protein 33B
ZNF552 zinc finger protein 552
ZNF654 zinc finger protein 654