nitrofurantoin-4697 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

193 genes differentially expressed following the nitrofurantoin-4697 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACRV1 acrosomal vesicle protein 1
AJAP1 adherens junctions associated protein 1
AK1 adenylate kinase 1
ARL2BP ADP-ribosylation factor-like 2 binding protein
BCL2A1 BCL2-related protein A1
BLZF1 basic leucine zipper nuclear factor 1
BRINP2 bone morphogenetic protein/retinoic acid inducible neural-specific 2
BTF3P11 basic transcription factor 3 pseudogene 11
BTG2 BTG family, member 2
C14ORF79 chromosome 14 open reading frame 79
C1ORF105 chromosome 1 open reading frame 105
C7ORF26 chromosome 7 open reading frame 26
CAMK1D calcium/calmodulin-dependent protein kinase ID
CCDC121 coiled-coil domain containing 121
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2)
CD248 CD248 molecule, endosialin
CD34 CD34 molecule
CD58 CD58 molecule
CDC25C cell division cycle 25C
COBLL1 cordon-bleu WH2 repeat protein-like 1
CREM cAMP responsive element modulator
CYHR1 cysteine/histidine-rich 1
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
EMC1 ER membrane protein complex subunit 1
ETAA1 Ewing tumor-associated antigen 1
ETV6 ets variant 6
EVA1B eva-1 homolog B (C. elegans)
EXPH5 exophilin 5
FANCA Fanconi anemia, complementation group A
FBLN1 fibulin 1
FCGBP Fc fragment of IgG binding protein
FGD1 FYVE, RhoGEF and PH domain containing 1
FMOD fibromodulin
FRZB frizzled-related protein
FSCN1 fascin actin-bundling protein 1
GALC galactosylceramidase
GFI1 growth factor independent 1 transcription repressor
GHRHR growth hormone releasing hormone receptor
GID4 GID complex subunit 4
GNPTAB N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits
GNRHR gonadotropin-releasing hormone receptor
HCN2 hyperpolarization activated cyclic nucleotide gated potassium channel 2
HFE hemochromatosis
HIST1H2BC histone cluster 1, H2bc
HIST1H3E histone cluster 1, H3e
HOXA1 homeobox A1
HSPG2 heparan sulfate proteoglycan 2
IFI6 interferon, alpha-inducible protein 6
IL23A interleukin 23, alpha subunit p19
IL5RA interleukin 5 receptor, alpha
ING4 inhibitor of growth family, member 4
JMJD4 jumonji domain containing 4
KCNJ3 potassium channel, inwardly rectifying subfamily J, member 3
KLF2 Kruppel-like factor 2
KRT17 keratin 17, type I
LIG4 ligase IV, DNA, ATP-dependent
LPIN1 lipin 1
LRP12 low density lipoprotein receptor-related protein 12
LTBP4 latent transforming growth factor beta binding protein 4
LZTS3 leucine zipper, putative tumor suppressor family member 3
MCTP2 multiple C2 domains, transmembrane 2
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1
MMP17 matrix metallopeptidase 17 (membrane-inserted)
MMP3 matrix metallopeptidase 3
MNDA myeloid cell nuclear differentiation antigen
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
NCOA2 nuclear receptor coactivator 2
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NME5 NME/NM23 family member 5
OSGIN2 oxidative stress induced growth inhibitor family member 2
PARD6B par-6 family cell polarity regulator beta
PATZ1 POZ (BTB) and AT hook containing zinc finger 1
PAWR PRKC, apoptosis, WT1, regulator
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PCDHGB5 protocadherin gamma subfamily B, 5
PHLPP2 PH domain and leucine rich repeat protein phosphatase 2
PLAC1 placenta-specific 1
PLVAP plasmalemma vesicle associated protein
PSCA prostate stem cell antigen
QKI QKI, KH domain containing, RNA binding
QSER1 glutamine and serine rich 1
RAB6B RAB6B, member RAS oncogene family
RBBP9 retinoblastoma binding protein 9
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RIN3 Ras and Rab interactor 3
RS1 retinoschisin 1
SCAND2P SCAN domain containing 2 pseudogene
SCRN3 secernin 3
SFI1 Sfi1 homolog, spindle assembly associated (yeast)
SH3BP1 SH3-domain binding protein 1
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
TAPBP TAP binding protein (tapasin)
TFF2 trefoil factor 2
TMEM19 transmembrane protein 19
VWA5A von Willebrand factor A domain containing 5A
YIF1B Yip1 interacting factor homolog B (S. cerevisiae)
ZFP64 ZFP64 zinc finger protein

decreased expression

Symbol Name
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase
ARC activity-regulated cytoskeleton-associated protein
BCAS1 breast carcinoma amplified sequence 1
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
C2ORF27A chromosome 2 open reading frame 27A
C2ORF54 chromosome 2 open reading frame 54
C7ORF69 chromosome 7 open reading frame 69
CAPN5 calpain 5
CCDC132 coiled-coil domain containing 132
CD3EAP CD3e molecule, epsilon associated protein
CD79B CD79b molecule, immunoglobulin-associated beta
CDHR2 cadherin-related family member 2
CLCN6 chloride channel, voltage-sensitive 6
CORT cortistatin
CYP4F11 cytochrome P450, family 4, subfamily F, polypeptide 11
DCAF13 DDB1 and CUL4 associated factor 13
DSCAM Down syndrome cell adhesion molecule
DTX2 deltex 2, E3 ubiquitin ligase
DUSP8 dual specificity phosphatase 8
DYSF dysferlin
ERCC4 excision repair cross-complementation group 4
FANCC Fanconi anemia, complementation group C
FGF23 fibroblast growth factor 23
FLCN folliculin
FLJ21369 uncharacterized protein FLJ21369
GAMT guanidinoacetate N-methyltransferase
GEMIN8 gem (nuclear organelle) associated protein 8
HPN hepsin
IMPDH1 IMP (inosine 5'-monophosphate) dehydrogenase 1
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
KDM8 lysine (K)-specific demethylase 8
KRT31 keratin 31, type I
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MFAP2 microfibrillar-associated protein 2
MUC3B mucin 3B, cell surface associated
MYLK myosin light chain kinase
MYO1F myosin IF
N4BP3 NEDD4 binding protein 3
NAG18 NAG18 mRNA
NAT6 N-acetyltransferase 6 (GCN5-related)
NCAM2 neural cell adhesion molecule 2
NDST2 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2
NEUROD1 neuronal differentiation 1
PDE12 phosphodiesterase 12
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PGP phosphoglycolate phosphatase
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PITX2 paired-like homeodomain 2
PLAT plasminogen activator, tissue
POM121 POM121 transmembrane nucleoporin
POMT2 protein-O-mannosyltransferase 2
PPP2R5B protein phosphatase 2, regulatory subunit B', beta
PTPRCAP protein tyrosine phosphatase, receptor type, C-associated protein
QPCT glutaminyl-peptide cyclotransferase
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RNF208 ring finger protein 208
RPAP1 RNA polymerase II associated protein 1
RPAP2 RNA polymerase II associated protein 2
SAA3P serum amyloid A3 pseudogene
SCAMP4 secretory carrier membrane protein 4
SLC12A8 solute carrier family 12, member 8
SLC26A6 solute carrier family 26 (anion exchanger), member 6
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
SLIT2 slit homolog 2 (Drosophila)
SP1 Sp1 transcription factor
SPINK5 serine peptidase inhibitor, Kazal type 5
SPRYD7 SPRY domain containing 7
SREK1IP1 SREK1-interacting protein 1
STAG3L4 stromal antigen 3-like 4 (pseudogene)
STEAP4 STEAP family member 4
TEP1 telomerase-associated protein 1
TET3 tet methylcytosine dioxygenase 3
TH tyrosine hydroxylase
THBS3 thrombospondin 3
TICAM1 toll-like receptor adaptor molecule 1
TIGD6 tigger transposable element derived 6
TMEM120B transmembrane protein 120B
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TNS2 tensin 2
TPRA1 transmembrane protein, adipocyte asscociated 1
TTC26 tetratricopeptide repeat domain 26
TUBA3D tubulin, alpha 3d
TUBB2B tubulin, beta 2B class IIb
UBQLN4 ubiquilin 4
UNC93B1 unc-93 homolog B1 (C. elegans)
USP20 ubiquitin specific peptidase 20
VIPR1 vasoactive intestinal peptide receptor 1
WDR76 WD repeat domain 76
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
ZNF675 zinc finger protein 675
ZNF696 zinc finger protein 696
ZNF747 zinc finger protein 747
ZNF862 zinc finger protein 862