nitrofural-6721 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the nitrofural-6721 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A1CF APOBEC1 complementation factor
AAGAB alpha- and gamma-adaptin binding protein
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6
AGFG1 ArfGAP with FG repeats 1
AIF1 allograft inflammatory factor 1
ALK anaplastic lymphoma receptor tyrosine kinase
AMPH amphiphysin
ANKLE2 ankyrin repeat and LEM domain containing 2
ANKRD12 ankyrin repeat domain 12
APOA1 apolipoprotein A-I
ATF6B activating transcription factor 6 beta
ATXN7L1 ataxin 7-like 1
BBC3 BCL2 binding component 3
BEX1 brain expressed, X-linked 1
BRF1 BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit
CD58 CD58 molecule
CDC14B cell division cycle 14B
CEP290 centrosomal protein 290kDa
CHMP6 charged multivesicular body protein 6
CLEC4E C-type lectin domain family 4, member E
CTNS cystinosin, lysosomal cystine transporter
CYTH3 cytohesin 3
DDO D-aspartate oxidase
DNAJC24 DnaJ (Hsp40) homolog, subfamily C, member 24
EEF1D eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)
EGR1 early growth response 1
ESRRG estrogen-related receptor gamma
EZR ezrin
F5 coagulation factor V (proaccelerin, labile factor)
FAM134B family with sequence similarity 134, member B
FLT1 fms-related tyrosine kinase 1
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2
GPR19 G protein-coupled receptor 19
GPR22 G protein-coupled receptor 22
GUK1 guanylate kinase 1
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HOXC4 homeobox C4
IER3IP1 immediate early response 3 interacting protein 1
IL2RG interleukin 2 receptor, gamma
KATNB1 katanin p80 (WD repeat containing) subunit B 1
KDELR3 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
KIDINS220 kinase D-interacting substrate, 220kDa
L3MBTL1 l(3)mbt-like 1 (Drosophila)
LGALS8 lectin, galactoside-binding, soluble, 8
LMOD1 leiomodin 1 (smooth muscle)
MAGEA5 melanoma antigen family A5
MRPL41 mitochondrial ribosomal protein L41
MRPL52 mitochondrial ribosomal protein L52
MS4A6A membrane-spanning 4-domains, subfamily A, member 6A
MSRB2 methionine sulfoxide reductase B2
MST1 macrophage stimulating 1
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1
OAZ3 ornithine decarboxylase antizyme 3
OCLM oculomedin
PDCD2 programmed cell death 2
PDE2A phosphodiesterase 2A, cGMP-stimulated
PHF14 PHD finger protein 14
PLCL2 phospholipase C-like 2
PMCH pro-melanin-concentrating hormone
PMCHL1 pro-melanin-concentrating hormone-like 1, pseudogene
PMS2P3 postmeiotic segregation increased 2 pseudogene 3
PRRC2C proline-rich coiled-coil 2C
REC8 REC8 meiotic recombination protein
REPS1 RALBP1 associated Eps domain containing 1
RMND5B required for meiotic nuclear division 5 homolog B (S. cerevisiae)
RPL10 ribosomal protein L10
RPL10L ribosomal protein L10-like
RPL14 ribosomal protein L14
RPL27A ribosomal protein L27a
RPLP2 ribosomal protein, large, P2
RPS11 ribosomal protein S11
RQCD1 RCD1 required for cell differentiation1 homolog (S. pombe)
SAFB scaffold attachment factor B
SLC24A1 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
SLC25A30 solute carrier family 25, member 30
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5
SNAP25 synaptosomal-associated protein, 25kDa
SNTB1 syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)
SNX13 sorting nexin 13
SPTBN5 spectrin, beta, non-erythrocytic 5
STOM stomatin
SUSD5 sushi domain containing 5
TGFB2 transforming growth factor, beta 2
TP53 tumor protein p53
TRD T cell receptor delta locus
UBE2I ubiquitin-conjugating enzyme E2I
URB1 URB1 ribosome biogenesis 1 homolog (S. cerevisiae)
VWA5A von Willebrand factor A domain containing 5A
WAPAL wings apart-like homolog (Drosophila)
ZBTB20 zinc finger and BTB domain containing 20
ZC3H13 zinc finger CCCH-type containing 13
ZNF268 zinc finger protein 268
ZNF500 zinc finger protein 500
ZNF573 zinc finger protein 573

decreased expression

Symbol Name
ANKZF1 ankyrin repeat and zinc finger domain containing 1
APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C
ARRB2 arrestin, beta 2
ATAD5 ATPase family, AAA domain containing 5
ATP13A2 ATPase type 13A2
BGLAP bone gamma-carboxyglutamate (gla) protein
BSCL2 Berardinelli-Seip congenital lipodystrophy 2 (seipin)
C11ORF68 chromosome 11 open reading frame 68
CARHSP1 calcium regulated heat stable protein 1, 24kDa
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCNJL cyclin J-like
CEP85 centrosomal protein 85kDa
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHM choroideremia (Rab escort protein 1)
CLDN4 claudin 4
CORO1A coronin, actin binding protein, 1A
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
DDA1 DET1 and DDB1 associated 1
DHRS11 dehydrogenase/reductase (SDR family) member 11
EEF1A2 eukaryotic translation elongation factor 1 alpha 2
EFNB1 ephrin-B1
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
ERCC3 excision repair cross-complementation group 3
ERF Ets2 repressor factor
EXOC5 exocyst complex component 5
FAM53B family with sequence similarity 53, member B
GALK1 galactokinase 1
GINS4 GINS complex subunit 4 (Sld5 homolog)
GNL1 guanine nucleotide binding protein-like 1
GTF2I general transcription factor IIi
GYS1 glycogen synthase 1 (muscle)
HDHD3 haloacid dehalogenase-like hydrolase domain containing 3
HOMER2 homer scaffolding protein 2
HOXA4 homeobox A4
HP1BP3 heterochromatin protein 1, binding protein 3
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IFI30 interferon, gamma-inducible protein 30
IGFBP4 insulin-like growth factor binding protein 4
IPO8 importin 8
IRAK4 interleukin-1 receptor-associated kinase 4
KCTD7 potassium channel tetramerization domain containing 7
KPNA5 karyopherin alpha 5 (importin alpha 6)
KRT8P12 keratin 8 pseudogene 12
LIME1 Lck interacting transmembrane adaptor 1
LSM7 LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae)
LY6E lymphocyte antigen 6 complex, locus E
MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2
MED15 mediator complex subunit 15
METTL16 methyltransferase like 16
MPDU1 mannose-P-dolichol utilization defect 1
MXD3 MAX dimerization protein 3
NABP2 nucleic acid binding protein 2
NBEAL2 neurobeachin-like 2
NPFFR1 neuropeptide FF receptor 1
OSMR oncostatin M receptor
PCOLCE procollagen C-endopeptidase enhancer
PDE8B phosphodiesterase 8B
PFN1 profilin 1
PHC1 polyhomeotic homolog 1 (Drosophila)
PKM pyruvate kinase, muscle
POLA1 polymerase (DNA directed), alpha 1, catalytic subunit
POLM polymerase (DNA directed), mu
POLR2F polymerase (RNA) II (DNA directed) polypeptide F
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha
PTGES2 prostaglandin E synthase 2
QTRT1 queuine tRNA-ribosyltransferase 1
RAB5B RAB5B, member RAS oncogene family
RAD54L2 RAD54-like 2 (S. cerevisiae)
RPL11 ribosomal protein L11
SETD8 SET domain containing (lysine methyltransferase) 8
SH3GLB2 SH3-domain GRB2-like endophilin B2
SLC25A10 solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
SLC25A40 solute carrier family 25, member 40
SLC37A1 solute carrier family 37 (glucose-6-phosphate transporter), member 1
SLC50A1 solute carrier family 50 (sugar efflux transporter), member 1
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
SND1-IT1 SND1 intronic transcript 1
SPTBN2 spectrin, beta, non-erythrocytic 2
STK16 serine/threonine kinase 16
STRN striatin, calmodulin binding protein
STX5 syntaxin 5
TAF12 TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TEAD3 TEA domain family member 3
TLN1 talin 1
TPRA1 transmembrane protein, adipocyte asscociated 1
TSPAN1 tetraspanin 1
UBA1 ubiquitin-like modifier activating enzyme 1
UBQLN4 ubiquilin 4
UQCR10 ubiquinol-cytochrome c reductase, complex III subunit X
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
ZNF227 zinc finger protein 227
ZNF286A zinc finger protein 286A
ZNF358 zinc finger protein 358
ZNF654 zinc finger protein 654
ZNF667 zinc finger protein 667
ZNF711 zinc finger protein 711