nitrofural-2459 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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198 genes differentially expressed following the nitrofural-2459 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACE angiotensin I converting enzyme
AFF1 AF4/FMR2 family, member 1
APBB1IP amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
APLP2 amyloid beta (A4) precursor-like protein 2
ATP10B ATPase, class V, type 10B
ATP2A3 ATPase, Ca++ transporting, ubiquitous
BMP7 bone morphogenetic protein 7
CACNA1I calcium channel, voltage-dependent, T type, alpha 1I subunit
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like)
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CLSTN2 calsyntenin 2
CLTA clathrin, light chain A
COL18A1 collagen, type XVIII, alpha 1
COL5A2 collagen, type V, alpha 2
COL8A2 collagen, type VIII, alpha 2
COX11 COX11 cytochrome c oxidase copper chaperone
CREM cAMP responsive element modulator
CTBP2 C-terminal binding protein 2
CTDSPL CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like
CTRL chymotrypsin-like
DMXL2 Dmx-like 2
DNAJC4 DnaJ (Hsp40) homolog, subfamily C, member 4
DST dystonin
DUSP4 dual specificity phosphatase 4
ELK1 ELK1, member of ETS oncogene family
EML2 echinoderm microtubule associated protein like 2
EPS8L1 EPS8-like 1
EWSR1 EWS RNA-binding protein 1
FAM118A family with sequence similarity 118, member A
FCMR Fc fragment of IgM receptor
FGF4 fibroblast growth factor 4
FGF6 fibroblast growth factor 6
FKRP fukutin related protein
GJD2 gap junction protein, delta 2, 36kDa
GNAQ guanine nucleotide binding protein (G protein), q polypeptide
GPM6B glycoprotein M6B
GPR107 G protein-coupled receptor 107
GRM7 glutamate receptor, metabotropic 7
H2AFX H2A histone family, member X
HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4
HN1L hematological and neurological expressed 1-like
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
HTR7 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase
ICAM2 intercellular adhesion molecule 2
IL18RAP interleukin 18 receptor accessory protein
IL1R1 interleukin 1 receptor, type I
INO80B INO80 complex subunit B
IRF4 interferon regulatory factor 4
KAZALD1 Kazal-type serine peptidase inhibitor domain 1
KIF1A kinesin family member 1A
KLF12 Kruppel-like factor 12
LILRA6 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6
LTB4R leukotriene B4 receptor
MAX MYC associated factor X
MBTD1 mbt domain containing 1
MORN1 MORN repeat containing 1
MPPE1 metallophosphoesterase 1
MRC2 mannose receptor, C type 2
MYL10 myosin, light chain 10, regulatory
NEK9 NIMA-related kinase 9
NOL10 nucleolar protein 10
OLFM1 olfactomedin 1
OTUB1 OTU deubiquitinase, ubiquitin aldehyde binding 1
P2RY1 purinergic receptor P2Y, G-protein coupled, 1
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PI4K2A phosphatidylinositol 4-kinase type 2 alpha
PKN2 protein kinase N2
PLSCR3 phospholipid scramblase 3
POU5F1B POU class 5 homeobox 1B
PRKCQ protein kinase C, theta
RBFOX2 RNA binding protein, fox-1 homolog (C. elegans) 2
RECQL5 RecQ protein-like 5
RGS5 regulator of G-protein signaling 5
RPL10L ribosomal protein L10-like
SALL2 spalt-like transcription factor 2
SEC23A Sec23 homolog A (S. cerevisiae)
SEMA4F sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F
SIGLEC9 sialic acid binding Ig-like lectin 9
SLC22A17 solute carrier family 22, member 17
SLC22A5 solute carrier family 22 (organic cation/carnitine transporter), member 5
SLC35A2 solute carrier family 35 (UDP-galactose transporter), member A2
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SMPX small muscle protein, X-linked
SOS2 son of sevenless homolog 2 (Drosophila)
SOX13 SRY (sex determining region Y)-box 13
SPRED2 sprouty-related, EVH1 domain containing 2
SRRM2 serine/arginine repetitive matrix 2
ST3GAL4 ST3 beta-galactoside alpha-2,3-sialyltransferase 4
STOML1 stomatin (EPB72)-like 1
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
UBR2 ubiquitin protein ligase E3 component n-recognin 2
UBXN1 UBX domain protein 1
UTP18 UTP18 small subunit (SSU) processome component homolog (yeast)
WFDC2 WAP four-disulfide core domain 2
ZBED4 zinc finger, BED-type containing 4
ZFYVE9 zinc finger, FYVE domain containing 9
ZNF185 zinc finger protein 185 (LIM domain)
ZNF778 zinc finger protein 778

decreased expression

Symbol Name
A1CF APOBEC1 complementation factor
A4GNT alpha-1,4-N-acetylglucosaminyltransferase
ACPP acid phosphatase, prostate
ADRB2 adrenoceptor beta 2, surface
ADTRP androgen-dependent TFPI-regulating protein
AGPAT4 1-acylglycerol-3-phosphate O-acyltransferase 4
AMH anti-Mullerian hormone
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
ATP7A ATPase, Cu++ transporting, alpha polypeptide
BEST1 bestrophin 1
BHMT2 betaine--homocysteine S-methyltransferase 2
BPI bactericidal/permeability-increasing protein
C3ORF18 chromosome 3 open reading frame 18
CAND2 cullin-associated and neddylation-dissociated 2 (putative)
CES3 carboxylesterase 3
CHPF chondroitin polymerizing factor
CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1
COL9A2 collagen, type IX, alpha 2
CPTP ceramide-1-phosphate transfer protein
CYP2W1 cytochrome P450, family 2, subfamily W, polypeptide 1
DGKG diacylglycerol kinase, gamma 90kDa
DUSP8 dual specificity phosphatase 8
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
EPHB6 EPH receptor B6
FGF22 fibroblast growth factor 22
FGF23 fibroblast growth factor 23
FGGY FGGY carbohydrate kinase domain containing
FGL1 fibrinogen-like 1
FOSB FBJ murine osteosarcoma viral oncogene homolog B
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GJA8 gap junction protein, alpha 8, 50kDa
GK3P glycerol kinase 3 pseudogene
GPR20 G protein-coupled receptor 20
GPR21 G protein-coupled receptor 21
GPX2 glutathione peroxidase 2
GRB7 growth factor receptor-bound protein 7
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
HIST1H2AI histone cluster 1, H2ai
HIST1H2BN histone cluster 1, H2bn
HIST1H3H histone cluster 1, H3h
HOXA4 homeobox A4
HTR2B 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
ICAM5 intercellular adhesion molecule 5, telencephalin
IFI6 interferon, alpha-inducible protein 6
INO80D INO80 complex subunit D
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KIAA1107 KIAA1107
LNPEP leucyl/cystinyl aminopeptidase
LOC390998 ribosomal protein L10 pseudogene
LY6D lymphocyte antigen 6 complex, locus D
LZTS3 leucine zipper, putative tumor suppressor family member 3
MAPK10 mitogen-activated protein kinase 10
MCPH1 microcephalin 1
MDM4 MDM4, p53 regulator
MIR22HG MIR22 host gene
MMP3 matrix metallopeptidase 3
MUC3A mucin 3A, cell surface associated
MYOZ1 myozenin 1
NAP1L2 nucleosome assembly protein 1-like 2
NFE2L3 nuclear factor, erythroid 2-like 3
OXCT2 3-oxoacid CoA transferase 2
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime
PEMT phosphatidylethanolamine N-methyltransferase
PGGT1B protein geranylgeranyltransferase type I, beta subunit
PHACTR1 phosphatase and actin regulator 1
PIGZ phosphatidylinositol glycan anchor biosynthesis, class Z
PIP prolactin-induced protein
PODXL2 podocalyxin-like 2
PPT2 palmitoyl-protein thioesterase 2
PRICKLE3 prickle homolog 3 (Drosophila)
PRR14L proline rich 14-like
PRR7 proline rich 7 (synaptic)
PRSS12 protease, serine, 12 (neurotrypsin, motopsin)
RHBDF1 rhomboid 5 homolog 1 (Drosophila)
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1
SH2D4A SH2 domain containing 4A
SLC35F6 solute carrier family 35, member F6
SNAI1 snail family zinc finger 1
SOX12 SRY (sex determining region Y)-box 12
SPRR2B small proline-rich protein 2B
SRD5A3 steroid 5 alpha-reductase 3
TBC1D19 TBC1 domain family, member 19
TCTN2 tectonic family member 2
TMBIM1 transmembrane BAX inhibitor motif containing 1
TMC5 transmembrane channel-like 5
TMEM209 transmembrane protein 209
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TTC26 tetratricopeptide repeat domain 26
TUBA3C tubulin, alpha 3c
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
VEGFC vascular endothelial growth factor C
VEZT vezatin, adherens junctions transmembrane protein
ZFP37 ZFP37 zinc finger protein
ZNF10 zinc finger protein 10
ZNF197 zinc finger protein 197
ZNF250 zinc finger protein 250
ZNF254 zinc finger protein 254