nitrendipine-6464 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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196 genes differentially expressed following the nitrendipine-6464 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
ACTN2 actinin, alpha 2
ADAM22 ADAM metallopeptidase domain 22
ANGPTL2 angiopoietin-like 2
ANXA2P3 annexin A2 pseudogene 3
APOBEC3A apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A
ATP6V0A2 ATPase, H+ transporting, lysosomal V0 subunit a2
C1ORF95 chromosome 1 open reading frame 95
CACNA2D1 calcium channel, voltage-dependent, alpha 2/delta subunit 1
CAPN2 calpain 2, (m/II) large subunit
CD84 CD84 molecule
CLCA2 chloride channel accessory 2
CLSTN2 calsyntenin 2
COL11A1 collagen, type XI, alpha 1
COL1A1 collagen, type I, alpha 1
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CST2 cystatin SA
CTRB2 chymotrypsinogen B2
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
CYP7B1 cytochrome P450, family 7, subfamily B, polypeptide 1
DCAF4 DDB1 and CUL4 associated factor 4
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35
DMD dystrophin
DOCK6 dedicator of cytokinesis 6
EGFR epidermal growth factor receptor
EGR3 early growth response 3
FN1 fibronectin 1
FNTB farnesyltransferase, CAAX box, beta
GNPTAB N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits
GRIP2 glutamate receptor interacting protein 2
HCG4 HLA complex group 4 (non-protein coding)
HCRTR2 hypocretin (orexin) receptor 2
HGD homogentisate 1,2-dioxygenase
HIPK3 homeodomain interacting protein kinase 3
HLA-J major histocompatibility complex, class I, J (pseudogene)
HTR3A 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
HYAL4 hyaluronoglucosaminidase 4
ING1 inhibitor of growth family, member 1
INHBE inhibin, beta E
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KIAA0040 KIAA0040
KRT83 keratin 83, type II
KRTAP5-9 keratin associated protein 5-9
LEP leptin
LGALS4 lectin, galactoside-binding, soluble, 4
LTBP4 latent transforming growth factor beta binding protein 4
MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1
MIA2 melanoma inhibitory activity 2
MTCP1 mature T-cell proliferation 1
MTSS1L metastasis suppressor 1-like
MUC4 mucin 4, cell surface associated
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NIPAL3 NIPA-like domain containing 3
NT5M 5',3'-nucleotidase, mitochondrial
PAWR PRKC, apoptosis, WT1, regulator
PAX4 paired box 4
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PPARA peroxisome proliferator-activated receptor alpha
PPARD peroxisome proliferator-activated receptor delta
PPP1R37 protein phosphatase 1, regulatory subunit 37
PRSS12 protease, serine, 12 (neurotrypsin, motopsin)
PSD4 pleckstrin and Sec7 domain containing 4
PTPRCAP protein tyrosine phosphatase, receptor type, C-associated protein
PYHIN1 pyrin and HIN domain family, member 1
RECQL5 RecQ protein-like 5
RHBDD3 rhomboid domain containing 3
RNF6 ring finger protein (C3H2C3 type) 6
ROR2 receptor tyrosine kinase-like orphan receptor 2
S100A8 S100 calcium binding protein A8
SCN10A sodium channel, voltage gated, type X alpha subunit
SEC24D SEC24 family member D
SERHL2 serine hydrolase-like 2
SIRT5 sirtuin 5
SLC24A1 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SLCO1B1 solute carrier organic anion transporter family, member 1B1
SLFN12 schlafen family member 12
SMR3A submaxillary gland androgen regulated protein 3A
SPAG8 sperm associated antigen 8
SPN sialophorin
SSX7 synovial sarcoma, X breakpoint 7
STARD3 StAR-related lipid transfer (START) domain containing 3
STAT2 signal transducer and activator of transcription 2, 113kDa
TENM4 teneurin transmembrane protein 4
TFR2 transferrin receptor 2
TG thyroglobulin
TGFB2 transforming growth factor, beta 2
TGM2 transglutaminase 2
TTC22 tetratricopeptide repeat domain 22
TUBA3C tubulin, alpha 3c
UPK1A uroplakin 1A
UTS2 urotensin 2
XPNPEP2 X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound
ZFP36L2 ZFP36 ring finger protein-like 2
ZG16 zymogen granule protein 16
ZNF473 zinc finger protein 473

decreased expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
ABI3BP ABI family, member 3 (NESH) binding protein
ALKBH4 alkB, alkylation repair homolog 4 (E. coli)
ANKEF1 ankyrin repeat and EF-hand domain containing 1
ARID3B AT rich interactive domain 3B (BRIGHT-like)
BAG4 BCL2-associated athanogene 4
BBS7 Bardet-Biedl syndrome 7
BCL9 B-cell CLL/lymphoma 9
BEX4 brain expressed, X-linked 4
BHLHB9 basic helix-loop-helix domain containing, class B, 9
BPGM 2,3-bisphosphoglycerate mutase
C4ORF29 chromosome 4 open reading frame 29
CASD1 CAS1 domain containing 1
CCDC88C coiled-coil domain containing 88C
CEP85 centrosomal protein 85kDa
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11
CXXC4 CXXC finger protein 4
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DCAF13 DDB1 and CUL4 associated factor 13
DCLRE1A DNA cross-link repair 1A
ERN2 endoplasmic reticulum to nucleus signaling 2
EXD3 exonuclease 3'-5' domain containing 3
FAM204A family with sequence similarity 204, member A
GALK1 galactokinase 1
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2
GMEB1 glucocorticoid modulatory element binding protein 1
GPR87 G protein-coupled receptor 87
GSTA4 glutathione S-transferase alpha 4
GTF2A1 general transcription factor IIA, 1, 19/37kDa
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HIST1H1D histone cluster 1, H1d
HIST1H2AI histone cluster 1, H2ai
HOXC11 homeobox C11
HP1BP3 heterochromatin protein 1, binding protein 3
IRF2BP1 interferon regulatory factor 2 binding protein 1
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
KIAA0754 KIAA0754
KIAA1456 KIAA1456
KRT13 keratin 13, type I
LMO2 LIM domain only 2 (rhombotin-like 1)
LOC642236 FSHD region gene 1 pseudogene
LYRM9 LYR motif containing 9
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAGEF1 melanoma antigen family F1
MITF microphthalmia-associated transcription factor
MRPS18C mitochondrial ribosomal protein S18C
MTERF1 mitochondrial transcription termination factor 1
N4BP3 NEDD4 binding protein 3
NDE1 nudE neurodevelopment protein 1
NECAP2 NECAP endocytosis associated 2
NPIPB15 nuclear pore complex interacting protein family, member B15
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18
NUP62CL nucleoporin 62kDa C-terminal like
OSGEPL1 O-sialoglycoprotein endopeptidase-like 1
PAIP2B poly(A) binding protein interacting protein 2B
PGGT1B protein geranylgeranyltransferase type I, beta subunit
PITX2 paired-like homeodomain 2
PLD2 phospholipase D2
PMCHL1 pro-melanin-concentrating hormone-like 1, pseudogene
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
PRSS16 protease, serine, 16 (thymus)
PRSS22 protease, serine, 22
RAB11FIP5 RAB11 family interacting protein 5 (class I)
RAB8B RAB8B, member RAS oncogene family
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
RIC8B RIC8 guanine nucleotide exchange factor B
RNF170 ring finger protein 170
RPGR retinitis pigmentosa GTPase regulator
RPL23AP32 ribosomal protein L23a pseudogene 32
SIGLEC15 sialic acid binding Ig-like lectin 15
SKA1 spindle and kinetochore associated complex subunit 1
SLC12A8 solute carrier family 12, member 8
SLMO1 slowmo homolog 1 (Drosophila)
STAG3 stromal antigen 3
STK16 serine/threonine kinase 16
SYBU syntabulin (syntaxin-interacting)
SYCP2 synaptonemal complex protein 2
TBX19 T-box 19
TCHH trichohyalin
TICAM1 toll-like receptor adaptor molecule 1
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TMEM183A transmembrane protein 183A
TRABD TraB domain containing
TTC33 tetratricopeptide repeat domain 33
VASH1 vasohibin 1
VCPIP1 valosin containing protein (p97)/p47 complex interacting protein 1
VIM vimentin
WDR25 WD repeat domain 25
WDR76 WD repeat domain 76
WDR91 WD repeat domain 91
ZBTB39 zinc finger and BTB domain containing 39
ZMAT5 zinc finger, matrin-type 5
ZNF212 zinc finger protein 212
ZNF35 zinc finger protein 35
ZNF37BP zinc finger protein 37B, pseudogene
ZNF778 zinc finger protein 778