nimodipine-6480 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the nimodipine-6480 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A2M alpha-2-macroglobulin
AAGAB alpha- and gamma-adaptin binding protein
AASS aminoadipate-semialdehyde synthase
ABCD4 ATP-binding cassette, sub-family D (ALD), member 4
ABHD6 abhydrolase domain containing 6
ACVR1B activin A receptor, type IB
ADAM22 ADAM metallopeptidase domain 22
ADAM3A ADAM metallopeptidase domain 3A (pseudogene)
ADGRE2 adhesion G protein-coupled receptor E2
ADGRL1 adhesion G protein-coupled receptor L1
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
AKT3 v-akt murine thymoma viral oncogene homolog 3
APBA1 amyloid beta (A4) precursor protein-binding, family A, member 1
APBA2 amyloid beta (A4) precursor protein-binding, family A, member 2
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17
ART4 ADP-ribosyltransferase 4 (Dombrock blood group)
ARTN artemin
ATP6V1B1 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1
BTG4 B-cell translocation gene 4
C10ORF12 chromosome 10 open reading frame 12
C14ORF79 chromosome 14 open reading frame 79
CASP1 caspase 1, apoptosis-related cysteine peptidase
CDKN2A cyclin-dependent kinase inhibitor 2A
CHD5 chromodomain helicase DNA binding protein 5
CHRNA4 cholinergic receptor, nicotinic, alpha 4 (neuronal)
COA1 cytochrome c oxidase assembly factor 1 homolog (S. cerevisiae)
COL14A1 collagen, type XIV, alpha 1
COMT catechol-O-methyltransferase
CPN2 carboxypeptidase N, polypeptide 2
CRYAB crystallin, alpha B
CST4 cystatin S
CTIF CBP80/20-dependent translation initiation factor
CUL7 cullin 7
CXCR2 chemokine (C-X-C motif) receptor 2
DEFA4 defensin, alpha 4, corticostatin
DGCR9 DiGeorge syndrome critical region gene 9 (non-protein coding)
DUOX2 dual oxidase 2
FAM182B family with sequence similarity 182, member B
FASLG Fas ligand (TNF superfamily, member 6)
FASTKD2 FAST kinase domains 2
FCGR2C Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)
FGB fibrinogen beta chain
FLJ11292
FPR1 formyl peptide receptor 1
FRMPD1 FERM and PDZ domain containing 1
G6PC2 glucose-6-phosphatase, catalytic, 2
GABRD gamma-aminobutyric acid (GABA) A receptor, delta
GLP1R glucagon-like peptide 1 receptor
GPR1 G protein-coupled receptor 1
GPR68 G protein-coupled receptor 68
GUCY1B3 guanylate cyclase 1, soluble, beta 3
HCN4 hyperpolarization activated cyclic nucleotide gated potassium channel 4
HFE hemochromatosis
ICOSLG inducible T-cell co-stimulator ligand
IFIH1 interferon induced with helicase C domain 1
IGFBP5 insulin-like growth factor binding protein 5
IL1RAP interleukin 1 receptor accessory protein
ITGB4 integrin, beta 4
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
MAP3K13 mitogen-activated protein kinase kinase kinase 13
MAPRE2 microtubule-associated protein, RP/EB family, member 2
MEG3 maternally expressed 3 (non-protein coding)
MFGE8 milk fat globule-EGF factor 8 protein
MTMR3 myotubularin related protein 3
NEURL1 neuralized E3 ubiquitin protein ligase 1
NPR1 natriuretic peptide receptor 1
NR4A2 nuclear receptor subfamily 4, group A, member 2
OASL 2'-5'-oligoadenylate synthetase-like
OXCT2 3-oxoacid CoA transferase 2
PARVA parvin, alpha
PCDH11Y protocadherin 11 Y-linked
PDE4DIP phosphodiesterase 4D interacting protein
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PHTF2 putative homeodomain transcription factor 2
PITX1 paired-like homeodomain 1
PLEKHG3 pleckstrin homology domain containing, family G (with RhoGef domain) member 3
POMT2 protein-O-mannosyltransferase 2
PPARD peroxisome proliferator-activated receptor delta
PTPRB protein tyrosine phosphatase, receptor type, B
RBM12B RNA binding motif protein 12B
RBP4 retinol binding protein 4, plasma
RUNX1 runt-related transcription factor 1
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SLC2A2 solute carrier family 2 (facilitated glucose transporter), member 2
SLC4A5 solute carrier family 4 (sodium bicarbonate cotransporter), member 5
SOX10 SRY (sex determining region Y)-box 10
SOX5 SRY (sex determining region Y)-box 5
ST3GAL6 ST3 beta-galactoside alpha-2,3-sialyltransferase 6
SVIL supervillin
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
TNXB tenascin XB
TRPV6 transient receptor potential cation channel, subfamily V, member 6
VAC14 Vac14 homolog (S. cerevisiae)
WNT8B wingless-type MMTV integration site family, member 8B
ZFPL1 zinc finger protein-like 1
ZNF532 zinc finger protein 532
ZNF814 zinc finger protein 814
ZXDB zinc finger, X-linked, duplicated B

decreased expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
ABI3BP ABI family, member 3 (NESH) binding protein
ACTL8 actin-like 8
ADGRG2 adhesion G protein-coupled receptor G2
ADM adrenomedullin
AGO3 argonaute RISC catalytic component 3
ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle)
ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28
ATAD5 ATPase family, AAA domain containing 5
BAHD1 bromo adjacent homology domain containing 1
C10ORF95 chromosome 10 open reading frame 95
C14ORF93 chromosome 14 open reading frame 93
CHRM3 cholinergic receptor, muscarinic 3
CIDEC cell death-inducing DFFA-like effector c
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
CXADR coxsackie virus and adenovirus receptor
CXXC4 CXXC finger protein 4
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
EFNA3 ephrin-A3
EGFL7 EGF-like-domain, multiple 7
F3 coagulation factor III (thromboplastin, tissue factor)
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FSTL3 follistatin-like 3 (secreted glycoprotein)
GLI3 GLI family zinc finger 3
GLTSCR1 glioma tumor suppressor candidate region gene 1
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GRAMD4 GRAM domain containing 4
GTF2I general transcription factor IIi
HIST1H1B histone cluster 1, H1b
HIST1H3I histone cluster 1, H3i
HOXC5 homeobox C5
HP1BP3 heterochromatin protein 1, binding protein 3
ICK intestinal cell (MAK-like) kinase
IL17RA interleukin 17 receptor A
IPO8 importin 8
IPP intracisternal A particle-promoted polypeptide
IREB2 iron-responsive element binding protein 2
IRF1 interferon regulatory factor 1
KREMEN2 kringle containing transmembrane protein 2
LOC100131532 uncharacterized LOC100131532
LOC257152 uncharacterized LOC257152
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
LRRC61 leucine rich repeat containing 61
LYRM9 LYR motif containing 9
MANBA mannosidase, beta A, lysosomal
MINOS1P1 mitochondrial inner membrane organizing system 1 pseudogene 1
NELL2 NEL-like 2 (chicken)
NFE2L3 nuclear factor, erythroid 2-like 3
NLGN1 neuroligin 1
NPTX1 neuronal pentraxin I
NRSN2 neurensin 2
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18
NUDT6 nudix (nucleoside diphosphate linked moiety X)-type motif 6
NUP62CL nucleoporin 62kDa C-terminal like
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
OTUD3 OTU deubiquitinase 3
OVGP1 oviductal glycoprotein 1, 120kDa
PADI1 peptidyl arginine deiminase, type I
PCBP4 poly(rC) binding protein 4
PCDHA9 protocadherin alpha 9
PHC1 polyhomeotic homolog 1 (Drosophila)
PHEX phosphate regulating endopeptidase homolog, X-linked
PLCXD1 phosphatidylinositol-specific phospholipase C, X domain containing 1
PLD2 phospholipase D2
PLEKHO2 pleckstrin homology domain containing, family O member 2
PMCHL1 pro-melanin-concentrating hormone-like 1, pseudogene
PROS1 protein S (alpha)
RAB23 RAB23, member RAS oncogene family
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
RPL23AP32 ribosomal protein L23a pseudogene 32
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SLMO1 slowmo homolog 1 (Drosophila)
SPINK4 serine peptidase inhibitor, Kazal type 4
STAG3L4 stromal antigen 3-like 4 (pseudogene)
STARD5 StAR-related lipid transfer (START) domain containing 5
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae)
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
SYCP2 synaptonemal complex protein 2
SYNGR3 synaptogyrin 3
THNSL2 threonine synthase-like 2 (S. cerevisiae)
TM6SF1 transmembrane 6 superfamily member 1
TMEM158 transmembrane protein 158 (gene/pseudogene)
TRDMT1 tRNA aspartic acid methyltransferase 1
TRPC5 transient receptor potential cation channel, subfamily C, member 5
TTC30A tetratricopeptide repeat domain 30A
TUBA3C tubulin, alpha 3c
UBTD1 ubiquitin domain containing 1
USP27X ubiquitin specific peptidase 27, X-linked
ZNF16 zinc finger protein 16
ZNF204P zinc finger protein 204, pseudogene
ZNF254 zinc finger protein 254
ZNF37BP zinc finger protein 37B, pseudogene
ZNF442 zinc finger protein 442
ZNF516 zinc finger protein 516
ZNF552 zinc finger protein 552
ZNF586 zinc finger protein 586
ZNF623 zinc finger protein 623
ZNF804A zinc finger protein 804A