nimesulide-7024 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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199 genes differentially expressed following the nimesulide-7024 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AKAP11 A kinase (PRKA) anchor protein 11
ANKRD12 ankyrin repeat domain 12
ARHGAP33 Rho GTPase activating protein 33
ASB1 ankyrin repeat and SOCS box containing 1
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
ATP6V0A4 ATPase, H+ transporting, lysosomal V0 subunit a4
BCL2L10 BCL2-like 10 (apoptosis facilitator)
BLVRA biliverdin reductase A
C2ORF54 chromosome 2 open reading frame 54
CALCR calcitonin receptor
CAMTA1 calmodulin binding transcription activator 1
CCDC186 coiled-coil domain containing 186
CCP110 centriolar coiled coil protein 110kDa
CCPG1 cell cycle progression 1
CD302 CD302 molecule
CELF3 CUGBP, Elav-like family member 3
CNNM2 cyclin and CBS domain divalent metal cation transport mediator 2
COL14A1 collagen, type XIV, alpha 1
CTDSPL CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like
CXXC4 CXXC finger protein 4
CYHR1 cysteine/histidine-rich 1
DDX52 DEAD (Asp-Glu-Ala-Asp) box polypeptide 52
DIEXF digestive organ expansion factor homolog (zebrafish)
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DUSP13 dual specificity phosphatase 13
ELK4 ELK4, ETS-domain protein (SRF accessory protein 1)
ELOVL5 ELOVL fatty acid elongase 5
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1
EXPH5 exophilin 5
FBXO42 F-box protein 42
FBXO9 F-box protein 9
FZD7 frizzled class receptor 7
GABRA1 gamma-aminobutyric acid (GABA) A receptor, alpha 1
GGA3 golgi-associated, gamma adaptin ear containing, ARF binding protein 3
GGPS1 geranylgeranyl diphosphate synthase 1
GLS2 glutaminase 2 (liver, mitochondrial)
GPR137 G protein-coupled receptor 137
HIST1H2AK histone cluster 1, H2ak
HIST1H3I histone cluster 1, H3i
HOXC10 homeobox C10
HOXC8 homeobox C8
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
IFNAR1 interferon (alpha, beta and omega) receptor 1
ING1 inhibitor of growth family, member 1
JAM3 junctional adhesion molecule 3
LIG3 ligase III, DNA, ATP-dependent
LZTR1 leucine-zipper-like transcription regulator 1
MAP2 microtubule-associated protein 2
MEGF9 multiple EGF-like-domains 9
MKL1 megakaryoblastic leukemia (translocation) 1
MMP15 matrix metallopeptidase 15 (membrane-inserted)
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NAB1 NGFI-A binding protein 1 (EGR1 binding protein 1)
NDRG4 NDRG family member 4
NF1 neurofibromin 1
ODF2 outer dense fiber of sperm tails 2
OGFOD2 2-oxoglutarate and iron-dependent oxygenase domain containing 2
OGFRL1 opioid growth factor receptor-like 1
PACS1 phosphofurin acidic cluster sorting protein 1
PAX9 paired box 9
PCDH11X protocadherin 11 X-linked
PCNXL2 pecanex-like 2 (Drosophila)
PDE3B phosphodiesterase 3B, cGMP-inhibited
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PIGC phosphatidylinositol glycan anchor biosynthesis, class C
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PLD2 phospholipase D2
POU6F2 POU class 6 homeobox 2
PPP2R5B protein phosphatase 2, regulatory subunit B', beta
PRB1 proline-rich protein BstNI subfamily 1
PRF1 perforin 1 (pore forming protein)
PTPN21 protein tyrosine phosphatase, non-receptor type 21
PYCRL pyrroline-5-carboxylate reductase-like
RAB36 RAB36, member RAS oncogene family
RAB3D RAB3D, member RAS oncogene family
RGS10 regulator of G-protein signaling 10
RNF39 ring finger protein 39
RPL23AP32 ribosomal protein L23a pseudogene 32
SASH1 SAM and SH3 domain containing 1
SBF1 SET binding factor 1
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
SLC15A1 solute carrier family 15 (oligopeptide transporter), member 1
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SLIT2 slit homolog 2 (Drosophila)
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SP100 SP100 nuclear antigen
SREK1IP1 SREK1-interacting protein 1
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
ST7 suppression of tumorigenicity 7
SYNJ2 synaptojanin 2
TM2D1 TM2 domain containing 1
TMEM183A transmembrane protein 183A
TREX1 three prime repair exonuclease 1
TTC33 tetratricopeptide repeat domain 33
WDR62 WD repeat domain 62
ZNF318 zinc finger protein 318
ZNF778 zinc finger protein 778

decreased expression

Symbol Name
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2
ACOX3 acyl-CoA oxidase 3, pristanoyl
AEN apoptosis enhancing nuclease
ASB9 ankyrin repeat and SOCS box containing 9
BAK1 BCL2-antagonist/killer 1
BCOR BCL6 corepressor
BMP4 bone morphogenetic protein 4
BRAF B-Raf proto-oncogene, serine/threonine kinase
C1ORF106 chromosome 1 open reading frame 106
CAMKMT calmodulin-lysine N-methyltransferase
CAPN5 calpain 5
CEP85 centrosomal protein 85kDa
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
CLUHP3 clustered mitochondria (cluA/CLU1) homolog pseudogene 3
COQ6 coenzyme Q6 monooxygenase
COX16 COX16 cytochrome c oxidase assembly homolog (S. cerevisiae)
CUEDC1 CUE domain containing 1
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DEPTOR DEP domain containing MTOR-interacting protein
DSCR3 Down syndrome critical region 3
DTWD1 DTW domain containing 1
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
EPHA2 EPH receptor A2
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FAM222B family with sequence similarity 222, member B
FANCE Fanconi anemia, complementation group E
FKBP14 FK506 binding protein 14, 22 kDa
FOXC1 forkhead box C1
GLB1L2 galactosidase, beta 1-like 2
GNE glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
GPR19 G protein-coupled receptor 19
GPR87 G protein-coupled receptor 87
GTF2A1 general transcription factor IIA, 1, 19/37kDa
H2AFY2 H2A histone family, member Y2
HGSNAT heparan-alpha-glucosaminide N-acetyltransferase
HIST1H2AG histone cluster 1, H2ag
HIST1H2AJ histone cluster 1, H2aj
HPS6 Hermansky-Pudlak syndrome 6
HPSE heparanase
IGBP1 immunoglobulin (CD79A) binding protein 1
IL15RA interleukin 15 receptor, alpha
IQSEC2 IQ motif and Sec7 domain 2
KCNK15 potassium channel, two pore domain subfamily K, member 15
KCTD20 potassium channel tetramerization domain containing 20
KLHL26 kelch-like family member 26
KRT13 keratin 13, type I
L2HGDH L-2-hydroxyglutarate dehydrogenase
LIN37 lin-37 DREAM MuvB core complex component
LRRC20 leucine rich repeat containing 20
LYPD1 LY6/PLAUR domain containing 1
METTL2B methyltransferase like 2B
MFSD10 major facilitator superfamily domain containing 10
MTA2 metastasis associated 1 family, member 2
MTERF1 mitochondrial transcription termination factor 1
NDRG1 N-myc downstream regulated 1
NECAB3 N-terminal EF-hand calcium binding protein 3
NHEJ1 nonhomologous end-joining factor 1
NKAIN1 Na+/K+ transporting ATPase interacting 1
NOTCH1 notch 1
NR1H3 nuclear receptor subfamily 1, group H, member 3
PCDHA6 protocadherin alpha 6
PDZRN3 PDZ domain containing ring finger 3
PPIP5K2 diphosphoinositol pentakisphosphate kinase 2
PRKX protein kinase, X-linked
PSMB10 proteasome (prosome, macropain) subunit, beta type, 10
RPL13P5 ribosomal protein L13 pseudogene 5
RPRM reprimo, TP53 dependent G2 arrest mediator candidate
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1
SLC12A9 solute carrier family 12, member 9
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
STAG3 stromal antigen 3
SUSD4 sushi domain containing 4
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TDRD1 tudor domain containing 1
TGFB3 transforming growth factor, beta 3
THBS3 thrombospondin 3
TMEM212 transmembrane protein 212
TRAPPC13 trafficking protein particle complex 13
TRIM5 tripartite motif containing 5
TRMT13 tRNA methyltransferase 13 homolog (S. cerevisiae)
TSPAN1 tetraspanin 1
TUBA3C tubulin, alpha 3c
UBQLN4 ubiquilin 4
UBXN6 UBX domain protein 6
UBXN8 UBX domain protein 8
ULBP2 UL16 binding protein 2
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
VWA1 von Willebrand factor A domain containing 1
WDR60 WD repeat domain 60
XPNPEP3 X-prolyl aminopeptidase 3, mitochondrial
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1
ZAK sterile alpha motif and leucine zipper containing kinase AZK
ZKSCAN3 zinc finger with KRAB and SCAN domains 3
ZNF180 zinc finger protein 180
ZNF189 zinc finger protein 189
ZNF408 zinc finger protein 408
ZNF668 zinc finger protein 668
ZNF767P zinc finger family member 767, pseudogene