nik/nf-kappab signaling Gene Set

Dataset GO Biological Process Annotations
Category structural or functional annotations
Type biological process
Description The process in which a signal is passed on to downstream components within the cell through the NIK-dependent processing and activation of NF-KappaB. Begins with activation of the NF-KappaB-inducing kinase (NIK), which in turn phosphorylates and activates IkappaB kinase alpha (IKKalpha). IKKalpha phosphorylates the NF-Kappa B2 protein (p100) leading to p100 processing and release of an active NF-KappaB (p52). (Gene Ontology, GO_0038061)
External Link http://amigo.geneontology.org/amigo/term/GO:0038061
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Genes

12 genes participating in the nik/nf-kappab signaling biological process from the curated GO Biological Process Annotations dataset.

Symbol Name
ALK anaplastic lymphoma receptor tyrosine kinase
BIRC2 baculoviral IAP repeat containing 2
BIRC3 baculoviral IAP repeat containing 3
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
MAP3K14 mitogen-activated protein kinase kinase kinase 14
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
PPP4C protein phosphatase 4, catalytic subunit
REL v-rel avian reticuloendotheliosis viral oncogene homolog
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RIPK3 receptor-interacting serine-threonine kinase 3