niflumic acid-7430 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the niflumic acid-7430 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
AKAP17A A kinase (PRKA) anchor protein 17A
ALDH4A1 aldehyde dehydrogenase 4 family, member A1
ASAP1-IT1 ASAP1 intronic transcript 1
ASPHD1 aspartate beta-hydroxylase domain containing 1
ATP2A3 ATPase, Ca++ transporting, ubiquitous
ATP6V1C1 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1
BBS9 Bardet-Biedl syndrome 9
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
BMP1 bone morphogenetic protein 1
BMP4 bone morphogenetic protein 4
C21ORF2 chromosome 21 open reading frame 2
C2CD2L C2CD2-like
CD6 CD6 molecule
CEACAM3 carcinoembryonic antigen-related cell adhesion molecule 3
COL1A1 collagen, type I, alpha 1
COQ7 coenzyme Q7 homolog, ubiquinone (yeast)
CUL2 cullin 2
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DST dystonin
DSTYK dual serine/threonine and tyrosine protein kinase
DUSP10 dual specificity phosphatase 10
EED embryonic ectoderm development
EHMT1 euchromatic histone-lysine N-methyltransferase 1
EPHA3 EPH receptor A3
FADS3 fatty acid desaturase 3
FAM214B family with sequence similarity 214, member B
FBLN1 fibulin 1
FBXL2 F-box and leucine-rich repeat protein 2
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
FGFR4 fibroblast growth factor receptor 4
FHL1 four and a half LIM domains 1
FLOT1 flotillin 1
GMEB1 glucocorticoid modulatory element binding protein 1
GRK5 G protein-coupled receptor kinase 5
GRTP1 growth hormone regulated TBC protein 1
GSTCD glutathione S-transferase, C-terminal domain containing
HAUS5 HAUS augmin-like complex, subunit 5
HCFC1 host cell factor C1
HMOX1 heme oxygenase 1
IFITM1 interferon induced transmembrane protein 1
IL4R interleukin 4 receptor
IPO9 importin 9
IRF6 interferon regulatory factor 6
KCNF1 potassium channel, voltage gated modifier subfamily F, member 1
KCNMB3 potassium channel subfamily M regulatory beta subunit 3
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
KDM6A lysine (K)-specific demethylase 6A
KLHL26 kelch-like family member 26
LOC399491
LONP2 lon peptidase 2, peroxisomal
LPCAT4 lysophosphatidylcholine acyltransferase 4
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
LUZP1 leucine zipper protein 1
MAPK14 mitogen-activated protein kinase 14
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2)
NDRG4 NDRG family member 4
NF2 neurofibromin 2 (merlin)
NOP14-AS1 NOP14 antisense RNA 1
NR1D2 nuclear receptor subfamily 1, group D, member 2
NR4A1 nuclear receptor subfamily 4, group A, member 1
OGFR opioid growth factor receptor
OTUD3 OTU deubiquitinase 3
PDLIM7 PDZ and LIM domain 7 (enigma)
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PLIN2 perilipin 2
PPAP2B phosphatidic acid phosphatase type 2B
PTPN21 protein tyrosine phosphatase, non-receptor type 21
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RARA retinoic acid receptor, alpha
RND2 Rho family GTPase 2
RPS4Y1 ribosomal protein S4, Y-linked 1
SASH1 SAM and SH3 domain containing 1
SCAPER S-phase cyclin A-associated protein in the ER
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SMR3A submaxillary gland androgen regulated protein 3A
SOS2 son of sevenless homolog 2 (Drosophila)
SRC SRC proto-oncogene, non-receptor tyrosine kinase
STK17B serine/threonine kinase 17b
STS steroid sulfatase (microsomal), isozyme S
STX7 syntaxin 7
TBC1D13 TBC1 domain family, member 13
TESK2 testis-specific kinase 2
TNFAIP8 tumor necrosis factor, alpha-induced protein 8
TOP3B topoisomerase (DNA) III beta
USB1 U6 snRNA biogenesis 1
VAC14 Vac14 homolog (S. cerevisiae)
VASH1 vasohibin 1
YIF1B Yip1 interacting factor homolog B (S. cerevisiae)
ZER1 zyg-11 related, cell cycle regulator
ZNF609 zinc finger protein 609
ZSCAN12 zinc finger and SCAN domain containing 12
ZZEF1 zinc finger, ZZ-type with EF-hand domain 1

decreased expression

Symbol Name
ABCA11P ATP-binding cassette, sub-family A (ABC1), member 11, pseudogene
ALPK1 alpha-kinase 1
AP1G2 adaptor-related protein complex 1, gamma 2 subunit
ARHGAP11A Rho GTPase activating protein 11A
BACE1 beta-site APP-cleaving enzyme 1
BCAS1 breast carcinoma amplified sequence 1
BLOC1S1 biogenesis of lysosomal organelles complex-1, subunit 1
C1ORF159 chromosome 1 open reading frame 159
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated
CASP3 caspase 3, apoptosis-related cysteine peptidase
CCDC88C coiled-coil domain containing 88C
CDK3 cyclin-dependent kinase 3
CGA glycoprotein hormones, alpha polypeptide
CLUHP3 clustered mitochondria (cluA/CLU1) homolog pseudogene 3
COBL cordon-bleu WH2 repeat protein
CORO1A coronin, actin binding protein, 1A
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like)
CTSK cathepsin K
CTSV cathepsin V
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1
DEAF1 DEAF1 transcription factor
EDC3 enhancer of mRNA decapping 3
EPPK1 epiplakin 1
FA2H fatty acid 2-hydroxylase
FAM86C1 family with sequence similarity 86, member C1
FBXL4 F-box and leucine-rich repeat protein 4
FBXO31 F-box protein 31
FGD6 FYVE, RhoGEF and PH domain containing 6
FMO4 flavin containing monooxygenase 4
FPGS folylpolyglutamate synthase
GAN gigaxonin
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2
GJA1 gap junction protein, alpha 1, 43kDa
GNL3LP1 guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1
GPATCH3 G patch domain containing 3
GPRASP1 G protein-coupled receptor associated sorting protein 1
GRB7 growth factor receptor-bound protein 7
HIRIP3 HIRA interacting protein 3
HIST1H4D histone cluster 1, H4d
HOXC10 homeobox C10
IMPACT impact RWD domain protein
INCENP inner centromere protein antigens 135/155kDa
IPO8 importin 8
KIAA0355 KIAA0355
KRT13 keratin 13, type I
LAMB2 laminin, beta 2 (laminin S)
LHPP phospholysine phosphohistidine inorganic pyrophosphate phosphatase
LHX1 LIM homeobox 1
LIN7B lin-7 homolog B (C. elegans)
MARC1 mitochondrial amidoxime reducing component 1
MFHAS1 malignant fibrous histiocytoma amplified sequence 1
NECAB3 N-terminal EF-hand calcium binding protein 3
NFE2L3 nuclear factor, erythroid 2-like 3
NINL ninein-like
NPY5R neuropeptide Y receptor Y5
NUP62CL nucleoporin 62kDa C-terminal like
OGFRL1 opioid growth factor receptor-like 1
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa)
PAN2 PAN2 poly(A) specific ribonuclease subunit
PARD6A par-6 family cell polarity regulator alpha
PCDHA6 protocadherin alpha 6
PCDHB3 protocadherin beta 3
PDLIM2 PDZ and LIM domain 2 (mystique)
PEX26 peroxisomal biogenesis factor 26
PGM1 phosphoglucomutase 1
PLEKHO1 pleckstrin homology domain containing, family O member 1
PP14571 uncharacterized LOC100130449
PRKRIP1 PRKR interacting protein 1 (IL11 inducible)
PROCR protein C receptor, endothelial
PTDSS2 phosphatidylserine synthase 2
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)
PTPN6 protein tyrosine phosphatase, non-receptor type 6
PUS7L pseudouridylate synthase 7 homolog (S. cerevisiae)-like
RAPGEF6 Rap guanine nucleotide exchange factor (GEF) 6
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
RHOBTB1 Rho-related BTB domain containing 1
RNF123 ring finger protein 123
RPH3AL rabphilin 3A-like (without C2 domains)
S100A4 S100 calcium binding protein A4
SH2B3 SH2B adaptor protein 3
SIRT6 sirtuin 6
SKA1 spindle and kinetochore associated complex subunit 1
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SMPDL3B sphingomyelin phosphodiesterase, acid-like 3B
SMYD5 SMYD family member 5
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
THOP1 thimet oligopeptidase 1
THRAP3 thyroid hormone receptor associated protein 3
TMEM57 transmembrane protein 57
TRPM4 transient receptor potential cation channel, subfamily M, member 4
TSC22D4 TSC22 domain family, member 4
TSPAN14 tetraspanin 14
TUBA3C tubulin, alpha 3c
ZC3H3 zinc finger CCCH-type containing 3
ZCCHC2 zinc finger, CCHC domain containing 2
ZNHIT2 zinc finger, HIT-type containing 2
ZSCAN26 zinc finger and SCAN domain containing 26