niflumic acid-5071 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the niflumic acid-5071 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACOXL acyl-CoA oxidase-like
ADARB1 adenosine deaminase, RNA-specific, B1
AGPAT4 1-acylglycerol-3-phosphate O-acyltransferase 4
ALLC allantoicase
ARC activity-regulated cytoskeleton-associated protein
ARHGEF15 Rho guanine nucleotide exchange factor (GEF) 15
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2
CBX2 chromobox homolog 2
CCZ1 CCZ1 vacuolar protein trafficking and biogenesis associated homolog (S. cerevisiae)
CHRNA4 cholinergic receptor, nicotinic, alpha 4 (neuronal)
CHRNG cholinergic receptor, nicotinic, gamma (muscle)
CHST4 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4
CLIC2 chloride intracellular channel 2
CNGB3 cyclic nucleotide gated channel beta 3
CRAT carnitine O-acetyltransferase
DENND4A DENN/MADD domain containing 4A
DGCR5 DiGeorge syndrome critical region gene 5 (non-protein coding)
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12
DOK3 docking protein 3
DRD1 dopamine receptor D1
DSTYK dual serine/threonine and tyrosine protein kinase
ELN elastin
EMC3 ER membrane protein complex subunit 3
EPN3 epsin 3
ERC2-IT1 ERC2 intronic transcript 1
FAM182B family with sequence similarity 182, member B
FGFR2 fibroblast growth factor receptor 2
FOXP3 forkhead box P3
GATA4 GATA binding protein 4
GIMAP5 GTPase, IMAP family member 5
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GSK3A glycogen synthase kinase 3 alpha
HECW1 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
HEG1 heart development protein with EGF-like domains 1
HIST1H2BM histone cluster 1, H2bm
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
IRF4 interferon regulatory factor 4
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
KCTD14 potassium channel tetramerization domain containing 14
KHDRBS2 KH domain containing, RNA binding, signal transduction associated 2
KYNU kynureninase
LARP7 La ribonucleoprotein domain family, member 7
LPPR1 lipid phosphate phosphatase-related protein type 1
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MST1 macrophage stimulating 1
NEUROD1 neuronal differentiation 1
NIPAL2 NIPA-like domain containing 2
NIPAL3 NIPA-like domain containing 3
NOP16 NOP16 nucleolar protein
NRAP nebulin-related anchoring protein
P2RX1 purinergic receptor P2X, ligand gated ion channel, 1
PADI4 peptidyl arginine deiminase, type IV
PCDH12 protocadherin 12
PDE11A phosphodiesterase 11A
PDE12 phosphodiesterase 12
PER1 period circadian clock 1
PHC3 polyhomeotic homolog 3 (Drosophila)
PID1 phosphotyrosine interaction domain containing 1
PIGO phosphatidylinositol glycan anchor biosynthesis, class O
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PKNOX1 PBX/knotted 1 homeobox 1
PKNOX2 PBX/knotted 1 homeobox 2
PLAG1 pleiomorphic adenoma gene 1
POM121 POM121 transmembrane nucleoporin
PPARA peroxisome proliferator-activated receptor alpha
PPP2R2B protein phosphatase 2, regulatory subunit B, beta
PTCRA pre T-cell antigen receptor alpha
PVT1 Pvt1 oncogene (non-protein coding)
RAD23B RAD23 homolog B (S. cerevisiae)
RBM12B-AS1 RBM12B antisense RNA 1
REEP2 receptor accessory protein 2
RIN3 Ras and Rab interactor 3
RNF122 ring finger protein 122
RNF126P1 ring finger protein 126 pseudogene 1
RYR2 ryanodine receptor 2 (cardiac)
SCAI suppressor of cancer cell invasion
SCN1B sodium channel, voltage gated, type I beta subunit
SEMA4F sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3
SIGLEC8 sialic acid binding Ig-like lectin 8
SLC15A1 solute carrier family 15 (oligopeptide transporter), member 1
SLC16A5 solute carrier family 16 (monocarboxylate transporter), member 5
SLC1A7 solute carrier family 1 (glutamate transporter), member 7
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced
THOC5 THO complex 5
TRIM33 tripartite motif containing 33
TRPM3 transient receptor potential cation channel, subfamily M, member 3
TUBB2B tubulin, beta 2B class IIb
USP20 ubiquitin specific peptidase 20
USP46 ubiquitin specific peptidase 46
WDR55 WD repeat domain 55
WNT5B wingless-type MMTV integration site family, member 5B
XAF1 XIAP associated factor 1
ZNF224 zinc finger protein 224
ZXDB zinc finger, X-linked, duplicated B

decreased expression

Symbol Name
ABCA3 ATP-binding cassette, sub-family A (ABC1), member 3
ADGRG2 adhesion G protein-coupled receptor G2
ARL14 ADP-ribosylation factor-like 14
BCL9 B-cell CLL/lymphoma 9
C16ORF59 chromosome 16 open reading frame 59
C1ORF159 chromosome 1 open reading frame 159
C1ORF56 chromosome 1 open reading frame 56
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated
CCBL1 cysteine conjugate-beta lyase, cytoplasmic
CCP110 centriolar coiled coil protein 110kDa
CD82 CD82 molecule
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1
DPF3 D4, zinc and double PHD fingers, family 3
EHF ets homologous factor
EPB41L5 erythrocyte membrane protein band 4.1 like 5
EPS8L2 EPS8-like 2
ERF Ets2 repressor factor
ETNK2 ethanolamine kinase 2
FAM114A2 family with sequence similarity 114, member A2
FAM155A family with sequence similarity 155, member A
FBXL7 F-box and leucine-rich repeat protein 7
FGF23 fibroblast growth factor 23
FRS3 fibroblast growth factor receptor substrate 3
FZD3 frizzled class receptor 3
GAL3ST4 galactose-3-O-sulfotransferase 4
GAS8 growth arrest-specific 8
GPX2 glutathione peroxidase 2
GTF2I general transcription factor IIi
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
HDAC5 histone deacetylase 5
HIST1H2BN histone cluster 1, H2bn
HOXA1 homeobox A1
HOXA4 homeobox A4
IL11RA interleukin 11 receptor, alpha
IL20RA interleukin 20 receptor, alpha
IQCG IQ motif containing G
IRAK4 interleukin-1 receptor-associated kinase 4
ITPKA inositol-trisphosphate 3-kinase A
KBTBD11 kelch repeat and BTB (POZ) domain containing 11
KCNMB4 potassium channel subfamily M regulatory beta subunit 4
KDM4D lysine (K)-specific demethylase 4D
LATS1 large tumor suppressor kinase 1
LIG4 ligase IV, DNA, ATP-dependent
LOC100286895 cell division cycle 27 homolog pseudogene
LOC100287590 uncharacterized LOC100287590
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
MAGEA6 melanoma antigen family A6
MAST3 microtubule associated serine/threonine kinase 3
MGP matrix Gla protein
MICALL2 MICAL-like 2
MNX1 motor neuron and pancreas homeobox 1
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
MTA2 metastasis associated 1 family, member 2
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NME5 NME/NM23 family member 5
NOD1 nucleotide-binding oligomerization domain containing 1
NXPH4 neurexophilin 4
ODF2 outer dense fiber of sperm tails 2
OSBP2 oxysterol binding protein 2
OTUB2 OTU deubiquitinase, ubiquitin aldehyde binding 2
PAK3 p21 protein (Cdc42/Rac)-activated kinase 3
PAX9 paired box 9
PBLD phenazine biosynthesis-like protein domain containing
PCYT2 phosphate cytidylyltransferase 2, ethanolamine
PHEX phosphate regulating endopeptidase homolog, X-linked
PRR15L proline rich 15-like
PRSS53 protease, serine, 53
PSKH1 protein serine kinase H1
RIBC2 RIB43A domain with coiled-coils 2
RPL13P5 ribosomal protein L13 pseudogene 5
RPP25 ribonuclease P/MRP 25kDa subunit
RRAGB Ras-related GTP binding B
RUSC2 RUN and SH3 domain containing 2
SERGEF secretion regulating guanine nucleotide exchange factor
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
STARD3 StAR-related lipid transfer (START) domain containing 3
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TGFBRAP1 transforming growth factor, beta receptor associated protein 1
TM6SF1 transmembrane 6 superfamily member 1
TMEM242 transmembrane protein 242
TMEM8A transmembrane protein 8A
TNK1 tyrosine kinase, non-receptor, 1
TRAPPC13 trafficking protein particle complex 13
TSC22D4 TSC22 domain family, member 4
TSKU tsukushi, small leucine rich proteoglycan
TTLL7 tubulin tyrosine ligase-like family member 7
USP18 ubiquitin specific peptidase 18
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
WDR25 WD repeat domain 25
ZNF254 zinc finger protein 254
ZNF286A zinc finger protein 286A
ZNF324 zinc finger protein 324
ZNF37BP zinc finger protein 37B, pseudogene
ZNF415 zinc finger protein 415
ZNF76 zinc finger protein 76
ZNF804A zinc finger protein 804A
ZNF862 zinc finger protein 862