nifenazone-6016 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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197 genes differentially expressed following the nifenazone-6016 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AGFG1 ArfGAP with FG repeats 1
ANKRD12 ankyrin repeat domain 12
ANXA2P3 annexin A2 pseudogene 3
AOX1 aldehyde oxidase 1
ARID4B AT rich interactive domain 4B (RBP1-like)
AURKA aurora kinase A
BAZ2A bromodomain adjacent to zinc finger domain, 2A
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein)
BIRC7 baculoviral IAP repeat containing 7
C11ORF16 chromosome 11 open reading frame 16
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CACNB2 calcium channel, voltage-dependent, beta 2 subunit
CACNG1 calcium channel, voltage-dependent, gamma subunit 1
CADM3 cell adhesion molecule 3
CCL21 chemokine (C-C motif) ligand 21
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CSE1L CSE1 chromosome segregation 1-like (yeast)
DICER1 dicer 1, ribonuclease type III
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12
DOK4 docking protein 4
DSTYK dual serine/threonine and tyrosine protein kinase
EEF1D eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)
EPHX2 epoxide hydrolase 2, cytoplasmic
EXPH5 exophilin 5
F2R coagulation factor II (thrombin) receptor
FBXL7 F-box and leucine-rich repeat protein 7
GAB1 GRB2-associated binding protein 1
GIF gastric intrinsic factor (vitamin B synthesis)
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GPATCH4 G patch domain containing 4
GPR15 G protein-coupled receptor 15
GUK1 guanylate kinase 1
HIST1H1B histone cluster 1, H1b
HLA-DMB major histocompatibility complex, class II, DM beta
HOXA10 homeobox A10
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
IFI35 interferon-induced protein 35
IL4R interleukin 4 receptor
ING2 inhibitor of growth family, member 2
ING4 inhibitor of growth family, member 4
ITM2C integral membrane protein 2C
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
LAT2 linker for activation of T cells family, member 2
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
MAP3K13 mitogen-activated protein kinase kinase kinase 13
MARK4 MAP/microtubule affinity-regulating kinase 4
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
MRPL41 mitochondrial ribosomal protein L41
MRPS18C mitochondrial ribosomal protein S18C
MXD4 MAX dimerization protein 4
NCKIPSD NCK interacting protein with SH3 domain
NF1 neurofibromin 1
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NGLY1 N-glycanase 1
NNAT neuronatin
ONECUT1 one cut homeobox 1
PARD3 par-3 family cell polarity regulator
PAWR PRKC, apoptosis, WT1, regulator
PAX2 paired box 2
PCDH17 protocadherin 17
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PDZD2 PDZ domain containing 2
PHEX phosphate regulating endopeptidase homolog, X-linked
PMCHL1 pro-melanin-concentrating hormone-like 1, pseudogene
PTBP3 polypyrimidine tract binding protein 3
PTCRA pre T-cell antigen receptor alpha
RAB3B RAB3B, member RAS oncogene family
RAD54L2 RAD54-like 2 (S. cerevisiae)
RFPL1S RFPL1 antisense RNA 1
RGS14 regulator of G-protein signaling 14
RGS4 regulator of G-protein signaling 4
RHEB Ras homolog enriched in brain
RPAIN RPA interacting protein
RPL35A ribosomal protein L35a
RPLP2 ribosomal protein, large, P2
RQCD1 RCD1 required for cell differentiation1 homolog (S. pombe)
S100A8 S100 calcium binding protein A8
SATB2 SATB homeobox 2
SHOX2 short stature homeobox 2
SIGLEC6 sialic acid binding Ig-like lectin 6
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4
SLC17A2 solute carrier family 17, member 2
SLC43A1 solute carrier family 43 (amino acid system L transporter), member 1
SLC44A1 solute carrier family 44 (choline transporter), member 1
STC1 stanniocalcin 1
TGFB2 transforming growth factor, beta 2
TMPRSS2 transmembrane protease, serine 2
TRIM21 tripartite motif containing 21
TUBA3C tubulin, alpha 3c
TXN thioredoxin
UBE2I ubiquitin-conjugating enzyme E2I
UBXN1 UBX domain protein 1
UTP18 UTP18 small subunit (SSU) processome component homolog (yeast)
VDAC3 voltage-dependent anion channel 3
VPS13B vacuolar protein sorting 13 homolog B (yeast)
ZNF224 zinc finger protein 224

decreased expression

Symbol Name
ACSL4 acyl-CoA synthetase long-chain family member 4
AKT2 v-akt murine thymoma viral oncogene homolog 2
ALPK1 alpha-kinase 1
AMH anti-Mullerian hormone
AMT aminomethyltransferase
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
B9D2 B9 protein domain 2
CA11 carbonic anhydrase XI
CAPG capping protein (actin filament), gelsolin-like
CAPN15 calpain 15
CASP3 caspase 3, apoptosis-related cysteine peptidase
CBX4 chromobox homolog 4
CCNO cyclin O
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2)
CDC42BPB CDC42 binding protein kinase beta (DMPK-like)
CDON cell adhesion associated, oncogene regulated
CENPT centromere protein T
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
CIC capicua transcriptional repressor
CLSPN claspin
CPPED1 calcineurin-like phosphoesterase domain containing 1
CRABP1 cellular retinoic acid binding protein 1
DGAT1 diacylglycerol O-acyltransferase 1
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
DNM1 dynamin 1
DRD1 dopamine receptor D1
FAM110B family with sequence similarity 110, member B
FAM155B family with sequence similarity 155, member B
FGL1 fibrinogen-like 1
FLCN folliculin
FLT4 fms-related tyrosine kinase 4
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GBF1 golgi brefeldin A resistant guanine nucleotide exchange factor 1
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GPR27 G protein-coupled receptor 27
HIST1H2AI histone cluster 1, H2ai
HIST1H2AJ histone cluster 1, H2aj
HLA-DMA major histocompatibility complex, class II, DM alpha
HOXA4 homeobox A4
HOXC10 homeobox C10
HOXD11 homeobox D11
HPN hepsin
IFI6 interferon, alpha-inducible protein 6
IFT81 intraflagellar transport 81
IL1RAPL2 interleukin 1 receptor accessory protein-like 2
IRF9 interferon regulatory factor 9
ITPKB inositol-trisphosphate 3-kinase B
JUNB jun B proto-oncogene
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KIAA0125 KIAA0125
KIZ kizuna centrosomal protein
LRFN3 leucine rich repeat and fibronectin type III domain containing 3
LRRC61 leucine rich repeat containing 61
LRRC8E leucine rich repeat containing 8 family, member E
LUZP1 leucine zipper protein 1
LY6E lymphocyte antigen 6 complex, locus E
MAST3 microtubule associated serine/threonine kinase 3
MID1IP1 MID1 interacting protein 1
MVP major vault protein
NPIPB15 nuclear pore complex interacting protein family, member B15
NR1H2 nuclear receptor subfamily 1, group H, member 2
NRSN2 neurensin 2
NUS1P3 nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) pseudogene 3
PDE12 phosphodiesterase 12
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PKM pyruvate kinase, muscle
PLA2G3 phospholipase A2, group III
PPIP5K1 diphosphoinositol pentakisphosphate kinase 1
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PQLC1 PQ loop repeat containing 1
PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta
PTPN14 protein tyrosine phosphatase, non-receptor type 14
RPAP1 RNA polymerase II associated protein 1
SCAMP4 secretory carrier membrane protein 4
SH2B3 SH2B adaptor protein 3
SLC16A10 solute carrier family 16 (aromatic amino acid transporter), member 10
SLC22A18AS solute carrier family 22 (organic cation transporter), member 18 antisense
SLC4A8 solute carrier family 4, sodium bicarbonate cotransporter, member 8
SND1-IT1 SND1 intronic transcript 1
SPINK5 serine peptidase inhibitor, Kazal type 5
ST3GAL1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1
STAG3L1 stromal antigen 3-like 1 (pseudogene)
SYMPK symplekin
TBC1D17 TBC1 domain family, member 17
THOP1 thimet oligopeptidase 1
TLN1 talin 1
TMEM183A transmembrane protein 183A
TMEM212 transmembrane protein 212
TUBA4A tubulin, alpha 4a
TWF2 twinfilin actin binding protein 2
ZDHHC18 zinc finger, DHHC-type containing 18
ZFHX3 zinc finger homeobox 3
ZNF219 zinc finger protein 219
ZNF365 zinc finger protein 365
ZNF623 zinc finger protein 623