nifedipine-7303 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the nifedipine-7303 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AMACR alpha-methylacyl-CoA racemase
ANKRD26 ankyrin repeat domain 26
APBA1 amyloid beta (A4) precursor protein-binding, family A, member 1
APP amyloid beta (A4) precursor protein
ARHGEF38 Rho guanine nucleotide exchange factor (GEF) 38
ATF3 activating transcription factor 3
BAZ2A bromodomain adjacent to zinc finger domain, 2A
CASP2 caspase 2, apoptosis-related cysteine peptidase
CD53 CD53 molecule
CD79A CD79a molecule, immunoglobulin-associated alpha
CDH10 cadherin 10, type 2 (T2-cadherin)
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CLCN5 chloride channel, voltage-sensitive 5
CNNM2 cyclin and CBS domain divalent metal cation transport mediator 2
COL1A1 collagen, type I, alpha 1
CPT1A carnitine palmitoyltransferase 1A (liver)
CREM cAMP responsive element modulator
CRYAB crystallin, alpha B
CSHL1 chorionic somatomammotropin hormone-like 1
CXCL8 chemokine (C-X-C motif) ligand 8
CYB561 cytochrome b561
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2
DENND2A DENN/MADD domain containing 2A
DSCR3 Down syndrome critical region 3
DUSP8 dual specificity phosphatase 8
DXO decapping exoribonuclease
EHMT2 euchromatic histone-lysine N-methyltransferase 2
ELK3 ELK3, ETS-domain protein (SRF accessory protein 2)
EPPK1 epiplakin 1
ERN2 endoplasmic reticulum to nucleus signaling 2
FBXO46 F-box protein 46
FLOT2 flotillin 2
GLRX3 glutaredoxin 3
GMPR guanosine monophosphate reductase
GPR107 G protein-coupled receptor 107
GPX3 glutathione peroxidase 3
GTF2I general transcription factor IIi
HAPLN1 hyaluronan and proteoglycan link protein 1
HIST1H2AK histone cluster 1, H2ak
HLA-DOA major histocompatibility complex, class II, DO alpha
HMGA1 high mobility group AT-hook 1
HMOX1 heme oxygenase 1
HOXA1 homeobox A1
HOXC8 homeobox C8
HSPA6 heat shock 70kDa protein 6 (HSP70B')
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
KIF5C kinesin family member 5C
KLHL20 kelch-like family member 20
LSM4 LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae)
MAP3K13 mitogen-activated protein kinase kinase kinase 13
METTL5 methyltransferase like 5
MTA1 metastasis associated 1
MTAP methylthioadenosine phosphorylase
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NDE1 nudE neurodevelopment protein 1
NDOR1 NADPH dependent diflavin oxidoreductase 1
NF2 neurofibromin 2 (merlin)
NNMT nicotinamide N-methyltransferase
NPEPL1 aminopeptidase-like 1
NUDT13 nudix (nucleoside diphosphate linked moiety X)-type motif 13
PHF20L1 PHD finger protein 20-like 1
PICALM phosphatidylinositol binding clathrin assembly protein
PITX1 paired-like homeodomain 1
PKP3 plakophilin 3
PMCH pro-melanin-concentrating hormone
PTK6 protein tyrosine kinase 6
PTPN11 protein tyrosine phosphatase, non-receptor type 11
RAB11B RAB11B, member RAS oncogene family
RAB4B RAB4B, member RAS oncogene family
RALGDS ral guanine nucleotide dissociation stimulator
RANBP1 RAN binding protein 1
RARA retinoic acid receptor, alpha
RPL14 ribosomal protein L14
RRN3P1 RNA polymerase I transcription factor homolog (S. cerevisiae) pseudogene 1
SARM1 sterile alpha and TIR motif containing 1
SEMA4G sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
SKIL SKI-like proto-oncogene
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SOX12 SRY (sex determining region Y)-box 12
STIM1 stromal interaction molecule 1
STX6 syntaxin 6
SYMPK symplekin
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TBX19 T-box 19
THOC5 THO complex 5
TLR5 toll-like receptor 5
TRIM25 tripartite motif containing 25
TUBA3C tubulin, alpha 3c
TUSC3 tumor suppressor candidate 3
TXNRD3 thioredoxin reductase 3
UTY ubiquitously transcribed tetratricopeptide repeat containing, Y-linked
WDR25 WD repeat domain 25
ZFYVE9 zinc finger, FYVE domain containing 9
ZNF219 zinc finger protein 219
ZNF609 zinc finger protein 609
ZNF675 zinc finger protein 675
ZNF768 zinc finger protein 768
ZNF93 zinc finger protein 93

decreased expression

Symbol Name
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
ANAPC2 anaphase promoting complex subunit 2
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
BAHCC1 BAH domain and coiled-coil containing 1
C11ORF71 chromosome 11 open reading frame 71
C17ORF80 chromosome 17 open reading frame 80
C5 complement component 5
CALCOCO1 calcium binding and coiled-coil domain 1
CAMTA2 calmodulin binding transcription activator 2
CCNE1 cyclin E1
CCP110 centriolar coiled coil protein 110kDa
CDON cell adhesion associated, oncogene regulated
CEP112 centrosomal protein 112kDa
CHMP6 charged multivesicular body protein 6
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4
CRADD CASP2 and RIPK1 domain containing adaptor with death domain
CRYBB2P1 crystallin, beta B2 pseudogene 1
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DLK1 delta-like 1 homolog (Drosophila)
DNA2 DNA replication helicase/nuclease 2
DSE dermatan sulfate epimerase
DYNC1I1 dynein, cytoplasmic 1, intermediate chain 1
EPHA4 EPH receptor A4
EYA4 EYA transcriptional coactivator and phosphatase 4
FAM131B family with sequence similarity 131, member B
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GLCE glucuronic acid epimerase
GPR87 G protein-coupled receptor 87
GRAMD4 GRAM domain containing 4
HIRA histone cell cycle regulator
HIST3H2A histone cluster 3, H2a
HSD3B2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
IFI6 interferon, alpha-inducible protein 6
IL18 interleukin 18
KDM5C lysine (K)-specific demethylase 5C
KIF16B kinesin family member 16B
MAMLD1 mastermind-like domain containing 1
MANBA mannosidase, beta A, lysosomal
MCM9 minichromosome maintenance complex component 9
MCMBP minichromosome maintenance complex binding protein
MCTP1 multiple C2 domains, transmembrane 1
MED24 mediator complex subunit 24
MED9 mediator complex subunit 9
MFGE8 milk fat globule-EGF factor 8 protein
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1
MN1 meningioma (disrupted in balanced translocation) 1
MNS1 meiosis-specific nuclear structural 1
MON1B MON1 secretory trafficking family member B
MT1F metallothionein 1F
NBEAL2 neurobeachin-like 2
NINJ1 ninjurin 1
NME5 NME/NM23 family member 5
NTSR1 neurotensin receptor 1 (high affinity)
PARN poly(A)-specific ribonuclease
PDE12 phosphodiesterase 12
PDZD2 PDZ domain containing 2
PISD phosphatidylserine decarboxylase
PLD2 phospholipase D2
PLD3 phospholipase D family, member 3
PPL periplakin
PRICKLE3 prickle homolog 3 (Drosophila)
PRR3 proline rich 3
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
RNF125 ring finger protein 125, E3 ubiquitin protein ligase
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
RPH3AL rabphilin 3A-like (without C2 domains)
S100A3 S100 calcium binding protein A3
SCAI suppressor of cancer cell invasion
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8
SH3TC2 SH3 domain and tetratricopeptide repeats 2
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4
SMPDL3A sphingomyelin phosphodiesterase, acid-like 3A
SNPH syntaphilin
SREBF1 sterol regulatory element binding transcription factor 1
ST5 suppression of tumorigenicity 5
STAR steroidogenic acute regulatory protein
SUPT5H suppressor of Ty 5 homolog (S. cerevisiae)
TAOK1 TAO kinase 1
TBXAS1 thromboxane A synthase 1 (platelet)
TGFB3 transforming growth factor, beta 3
TH tyrosine hydroxylase
TMCC2 transmembrane and coiled-coil domain family 2
TMEM184C transmembrane protein 184C
TMEM62 transmembrane protein 62
TPRA1 transmembrane protein, adipocyte asscociated 1
TRMU tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
TSKU tsukushi, small leucine rich proteoglycan
USP27X ubiquitin specific peptidase 27, X-linked
WDR60 WD repeat domain 60
WDR7 WD repeat domain 7
WNT7A wingless-type MMTV integration site family, member 7A
XPA xeroderma pigmentosum, complementation group A
ZC3H12A zinc finger CCCH-type containing 12A
ZNF107 zinc finger protein 107
ZNF165 zinc finger protein 165
ZNF34 zinc finger protein 34
ZNF654 zinc finger protein 654