nifedipine-335 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the nifedipine-335 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABHD2 abhydrolase domain containing 2
ADAM22 ADAM metallopeptidase domain 22
AGFG2 ArfGAP with FG repeats 2
AGRN agrin
AIM1L absent in melanoma 1-like
ANK1 ankyrin 1, erythrocytic
APBB1IP amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
ARAP3 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
ARNTL aryl hydrocarbon receptor nuclear translocator-like
ATP6V0A1 ATPase, H+ transporting, lysosomal V0 subunit a1
ATXN2L ataxin 2-like
BAZ2A bromodomain adjacent to zinc finger domain, 2A
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein)
CALY calcyon neuron-specific vesicular protein
CAV3 caveolin 3
CD19 CD19 molecule
CD2 CD2 molecule
CHD5 chromodomain helicase DNA binding protein 5
CHERP calcium homeostasis endoplasmic reticulum protein
CIDEA cell death-inducing DFFA-like effector a
CTDSPL CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
EFNB3 ephrin-B3
ELMO3 engulfment and cell motility 3
EMID1 EMI domain containing 1
EPHB1 EPH receptor B1
EXOC6B exocyst complex component 6B
FAM110D family with sequence similarity 110, member D
FAM188A family with sequence similarity 188, member A
FGR FGR proto-oncogene, Src family tyrosine kinase
FOXRED2 FAD-dependent oxidoreductase domain containing 2
FTCD formimidoyltransferase cyclodeaminase
FYB FYN binding protein
GAL3ST4 galactose-3-O-sulfotransferase 4
GJC1 gap junction protein, gamma 1, 45kDa
GSK3A glycogen synthase kinase 3 alpha
HIST1H3J histone cluster 1, H3j
HNF4A hepatocyte nuclear factor 4, alpha
HOXB7 homeobox B7
IL11 interleukin 11
IL5RA interleukin 5 receptor, alpha
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KIAA1467 KIAA1467
KIAA1614 KIAA1614
LAPTM5 lysosomal protein transmembrane 5
LHPP phospholysine phosphohistidine inorganic pyrophosphate phosphatase
LIN7A lin-7 homolog A (C. elegans)
LPPR2 lipid phosphate phosphatase-related protein type 2
LUZP1 leucine zipper protein 1
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MARC1 mitochondrial amidoxime reducing component 1
MFI2 antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5
MINK1 misshapen-like kinase 1
MMP8 matrix metallopeptidase 8
MTMR8 myotubularin related protein 8
MZF1 myeloid zinc finger 1
NOTCH3 notch 3
NR4A1 nuclear receptor subfamily 4, group A, member 1
NRGN neurogranin (protein kinase C substrate, RC3)
OGFR opioid growth factor receptor
OR2F2 olfactory receptor, family 2, subfamily F, member 2
ORC4 origin recognition complex, subunit 4
OVOL1 ovo-like zinc finger 1
PHC1 polyhomeotic homolog 1 (Drosophila)
PHF20 PHD finger protein 20
POLG polymerase (DNA directed), gamma
PRDM14 PR domain containing 14
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein)
PTPN7 protein tyrosine phosphatase, non-receptor type 7
REN renin
RFPL2 ret finger protein-like 2
RGR retinal G protein coupled receptor
SCLY selenocysteine lyase
SF3A2 splicing factor 3a, subunit 2, 66kDa
SH3GL3 SH3-domain GRB2-like 3
SIGLEC7 sialic acid binding Ig-like lectin 7
SIX6 SIX homeobox 6
SLC11A2 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
SPEG SPEG complex locus
SRPK2 SRSF protein kinase 2
STAG3 stromal antigen 3
STARD8 StAR-related lipid transfer (START) domain containing 8
SVEP1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
SYNGR1 synaptogyrin 1
TBL1X transducin (beta)-like 1X-linked
TCEA2 transcription elongation factor A (SII), 2
TMF1 TATA element modulatory factor 1
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
UBE2O ubiquitin-conjugating enzyme E2O
UCP1 uncoupling protein 1 (mitochondrial, proton carrier)
VAC14 Vac14 homolog (S. cerevisiae)
VCAM1 vascular cell adhesion molecule 1
ZNF117 zinc finger protein 117
ZNF3 zinc finger protein 3
ZNF460 zinc finger protein 460

decreased expression

Symbol Name
A2M alpha-2-macroglobulin
ACAD10 acyl-CoA dehydrogenase family, member 10
ACBD4 acyl-CoA binding domain containing 4
AHR aryl hydrocarbon receptor
ALPK1 alpha-kinase 1
APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ASIP agouti signaling protein
AXIN1 axin 1
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
BICD1 bicaudal D homolog 1 (Drosophila)
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
CA5BP1 carbonic anhydrase VB pseudogene 1
CDH22 cadherin 22, type 2
CEND1 cell cycle exit and neuronal differentiation 1
CLCN5 chloride channel, voltage-sensitive 5
CLDN14 claudin 14
CLPB ClpB homolog, mitochondrial AAA ATPase chaperonin
CLTCL1 clathrin, heavy chain-like 1
CNKSR1 connector enhancer of kinase suppressor of Ras 1
CRHBP corticotropin releasing hormone binding protein
CRTAC1 cartilage acidic protein 1
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CXORF56 chromosome X open reading frame 56
CYP20A1 cytochrome P450, family 20, subfamily A, polypeptide 1
CYP2B7P cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene
CYP2J2 cytochrome P450, family 2, subfamily J, polypeptide 2
DGKD diacylglycerol kinase, delta 130kDa
DHX8 DEAH (Asp-Glu-Ala-His) box polypeptide 8
ELP6 elongator acetyltransferase complex subunit 6
EPX eosinophil peroxidase
ERO1L ERO1-like (S. cerevisiae)
FLJ11710 uncharacterized protein FLJ11710
FOLR2 folate receptor 2 (fetal)
FOSL1 FOS-like antigen 1
FOXN2 forkhead box N2
GALK1 galactokinase 1
GPR19 G protein-coupled receptor 19
GPR21 G protein-coupled receptor 21
GUCA2A guanylate cyclase activator 2A (guanylin)
HDAC11 histone deacetylase 11
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3
HMHA1 histocompatibility (minor) HA-1
HMX1 H6 family homeobox 1
IRX4 iroquois homeobox 4
JOSD1 Josephin domain containing 1
KHDRBS3 KH domain containing, RNA binding, signal transduction associated 3
KLF2 Kruppel-like factor 2
L1TD1 LINE-1 type transposase domain containing 1
L2HGDH L-2-hydroxyglutarate dehydrogenase
LEFTY2 left-right determination factor 2
LHX6 LIM homeobox 6
LOC100127972 uncharacterized LOC100127972
LY6D lymphocyte antigen 6 complex, locus D
MAP3K6 mitogen-activated protein kinase kinase kinase 6
MCOLN1 mucolipin 1
MPP6 membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)
NDN necdin, melanoma antigen (MAGE) family member
NLRP2 NLR family, pyrin domain containing 2
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
ONECUT2 one cut homeobox 2
PCDHB3 protocadherin beta 3
PHEX phosphate regulating endopeptidase homolog, X-linked
PIGZ phosphatidylinositol glycan anchor biosynthesis, class Z
PNMT phenylethanolamine N-methyltransferase
PPP2R2D protein phosphatase 2, regulatory subunit B, delta
PRSS50 protease, serine, 50
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
RASIP1 Ras interacting protein 1
ROPN1B rhophilin associated tail protein 1B
RORC RAR-related orphan receptor C
RPAP2 RNA polymerase II associated protein 2
RSAD1 radical S-adenosyl methionine domain containing 1
SATB1 SATB homeobox 1
SCAI suppressor of cancer cell invasion
SETBP1 SET binding protein 1
SLC35F5 solute carrier family 35, member F5
SLC46A3 solute carrier family 46, member 3
SLC9A5 solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5
SOCS7 suppressor of cytokine signaling 7
SOX17 SRY (sex determining region Y)-box 17
SPRR2B small proline-rich protein 2B
T T, brachyury homolog (mouse)
TGM5 transglutaminase 5
TM7SF3 transmembrane 7 superfamily member 3
TMEM8B transmembrane protein 8B
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B
TUBA4B tubulin, alpha 4b
TUBB1 tubulin, beta 1 class VI
UBXN2B UBX domain protein 2B
USP18 ubiquitin specific peptidase 18
USP27X ubiquitin specific peptidase 27, X-linked
VCPIP1 valosin containing protein (p97)/p47 complex interacting protein 1
VIPR1 vasoactive intestinal peptide receptor 1
WDR18 WD repeat domain 18
WNT7A wingless-type MMTV integration site family, member 7A
XYLT1 xylosyltransferase I
XYLT2 xylosyltransferase II
ZNF652 zinc finger protein 652
ZSCAN31 zinc finger and SCAN domain containing 31