nicotinic acid-6702 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

193 genes differentially expressed following the nicotinic acid-6702 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCC9 ATP-binding cassette, sub-family C (CFTR/MRP), member 9
ABCD4 ATP-binding cassette, sub-family D (ALD), member 4
ACOX3 acyl-CoA oxidase 3, pristanoyl
ACVR1B activin A receptor, type IB
ALDH6A1 aldehyde dehydrogenase 6 family, member A1
ANP32A-IT1 ANP32A intronic transcript 1
APOBR apolipoprotein B receptor
ARTN artemin
BBC3 BCL2 binding component 3
C8ORF4 chromosome 8 open reading frame 4
CD6 CD6 molecule
CD79B CD79b molecule, immunoglobulin-associated beta
CDKL1 cyclin-dependent kinase-like 1 (CDC2-related kinase)
CHRNA4 cholinergic receptor, nicotinic, alpha 4 (neuronal)
CNGB3 cyclic nucleotide gated channel beta 3
COL2A1 collagen, type II, alpha 1
CSF2RA colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)
CTNS cystinosin, lysosomal cystine transporter
DAPK2 death-associated protein kinase 2
DIAPH2-AS1 DIAPH2 antisense RNA 1
DNASE1L3 deoxyribonuclease I-like 3
EML2 echinoderm microtubule associated protein like 2
EYA4 EYA transcriptional coactivator and phosphatase 4
F12 coagulation factor XII (Hageman factor)
FAM182A family with sequence similarity 182, member A
FGFR2 fibroblast growth factor receptor 2
FRMPD1 FERM and PDZ domain containing 1
GADD45G growth arrest and DNA-damage-inducible, gamma
GPR6 G protein-coupled receptor 6
GREB1L growth regulation by estrogen in breast cancer-like
HESX1 HESX homeobox 1
HIRA histone cell cycle regulator
HIST1H3C histone cluster 1, H3c
HLA-DOA major histocompatibility complex, class II, DO alpha
HLA-DRB4 major histocompatibility complex, class II, DR beta 4
HTR2C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled
IDS iduronate 2-sulfatase
IL11 interleukin 11
INHA inhibin, alpha
JUND jun D proto-oncogene
KCNJ1 potassium channel, inwardly rectifying subfamily J, member 1
KIAA0125 KIAA0125
KRT14 keratin 14, type I
LDLRAD4 low density lipoprotein receptor class A domain containing 4
LIMK1 LIM domain kinase 1
LMX1B LIM homeobox transcription factor 1, beta
MFAP3L microfibrillar-associated protein 3-like
MIR622 microRNA 622
MORC1 MORC family CW-type zinc finger 1
MYO1B myosin IB
NEUROD1 neuronal differentiation 1
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NKG7 natural killer cell granule protein 7
NRF1 nuclear respiratory factor 1
NRP2 neuropilin 2
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7
PALM paralemmin
PARVB parvin, beta
PATZ1 POZ (BTB) and AT hook containing zinc finger 1
PCDHGB6 protocadherin gamma subfamily B, 6
PDIA2 protein disulfide isomerase family A, member 2
PGLYRP4 peptidoglycan recognition protein 4
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
PRKACG protein kinase, cAMP-dependent, catalytic, gamma
PRKCA protein kinase C, alpha
PTGER1 prostaglandin E receptor 1 (subtype EP1), 42kDa
PTGIS prostaglandin I2 (prostacyclin) synthase
RAB36 RAB36, member RAS oncogene family
RBBP9 retinoblastoma binding protein 9
REC8 REC8 meiotic recombination protein
SFTPA2 surfactant protein A2
SLC6A9 solute carrier family 6 (neurotransmitter transporter, glycine), member 9
SLC7A10 solute carrier family 7 (neutral amino acid transporter light chain, asc system), member 10
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
SLC9A5 solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5
SLCO1C1 solute carrier organic anion transporter family, member 1C1
SNTB1 syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)
SOX5 SRY (sex determining region Y)-box 5
SPRR2B small proline-rich protein 2B
ST3GAL6 ST3 beta-galactoside alpha-2,3-sialyltransferase 6
SYMPK symplekin
TCL6 T-cell leukemia/lymphoma 6 (non-protein coding)
TF transferrin
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
TRIM3 tripartite motif containing 3
TUBA3C tubulin, alpha 3c
VPS16 vacuolar protein sorting 16 homolog (S. cerevisiae)
VPS53 vacuolar protein sorting 53 homolog (S. cerevisiae)
WDR55 WD repeat domain 55
XCL1 chemokine (C motif) ligand 1
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble
ZNRF4 zinc and ring finger 4

decreased expression

Symbol Name
ABCA3 ATP-binding cassette, sub-family A (ABC1), member 3
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle)
ARL14 ADP-ribosylation factor-like 14
B4GALNT1 beta-1,4-N-acetyl-galactosaminyl transferase 1
BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2
BEX1 brain expressed, X-linked 1
BGLAP bone gamma-carboxyglutamate (gla) protein
BTF3P12 basic transcription factor 3 pseudogene 12
C16ORF59 chromosome 16 open reading frame 59
C17ORF70 chromosome 17 open reading frame 70
C1ORF105 chromosome 1 open reading frame 105
C1ORF54 chromosome 1 open reading frame 54
C9ORF91 chromosome 9 open reading frame 91
CAND2 cullin-associated and neddylation-dissociated 2 (putative)
CASZ1 castor zinc finger 1
CCDC88C coiled-coil domain containing 88C
CCP110 centriolar coiled coil protein 110kDa
CEL carboxyl ester lipase
CEP131 centrosomal protein 131kDa
CHCHD7 coiled-coil-helix-coiled-coil-helix domain containing 7
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle)
CLDN8 claudin 8
CLIC3 chloride intracellular channel 3
CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1
CNTNAP3B contactin associated protein-like 3B
CRYBB2P1 crystallin, beta B2 pseudogene 1
CXORF56 chromosome X open reading frame 56
CYP7B1 cytochrome P450, family 7, subfamily B, polypeptide 1
DENND4A DENN/MADD domain containing 4A
EAF2 ELL associated factor 2
ETNK2 ethanolamine kinase 2
FBXW12 F-box and WD repeat domain containing 12
FKBP10 FK506 binding protein 10, 65 kDa
FLT4 fms-related tyrosine kinase 4
GALT galactose-1-phosphate uridylyltransferase
GID4 GID complex subunit 4
GMEB1 glucocorticoid modulatory element binding protein 1
GSTA3 glutathione S-transferase alpha 3
HIST2H2AA3 histone cluster 2, H2aa3
HSD17B8 hydroxysteroid (17-beta) dehydrogenase 8
IER3IP1 immediate early response 3 interacting protein 1
IGSF3 immunoglobulin superfamily, member 3
IL17RA interleukin 17 receptor A
IL2 interleukin 2
IL6 interleukin 6
IPO8 importin 8
KCNS3 potassium voltage-gated channel, modifier subfamily S, member 3
KRT9 keratin 9, type I
LOC202181 SUMO-interacting motifs containing 1 pseudogene
LY6G5C lymphocyte antigen 6 complex, locus G5C
MAGEA3 melanoma antigen family A3
MAGEF1 melanoma antigen family F1
MBTPS2 membrane-bound transcription factor peptidase, site 2
MGC12488
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MRPL44 mitochondrial ribosomal protein L44
MRPL52 mitochondrial ribosomal protein L52
MRPS18C mitochondrial ribosomal protein S18C
MUC3A mucin 3A, cell surface associated
NAALAD2 N-acetylated alpha-linked acidic dipeptidase 2
NAT6 N-acetyltransferase 6 (GCN5-related)
PCDHGB5 protocadherin gamma subfamily B, 5
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
PLAG1 pleiomorphic adenoma gene 1
PLD2 phospholipase D2
PMCH pro-melanin-concentrating hormone
POLL polymerase (DNA directed), lambda
PRF1 perforin 1 (pore forming protein)
PRR7 proline rich 7 (synaptic)
PTPRE protein tyrosine phosphatase, receptor type, E
RAI2 retinoic acid induced 2
RBL1 retinoblastoma-like 1
SCG5 secretogranin V
SCN10A sodium channel, voltage gated, type X alpha subunit
SCN8A sodium channel, voltage gated, type VIII alpha subunit
SFT2D2 SFT2 domain containing 2
SKI SKI proto-oncogene
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SLC4A3 solute carrier family 4 (anion exchanger), member 3
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
STAG3L4 stromal antigen 3-like 4 (pseudogene)
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae)
SYNGR3 synaptogyrin 3
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TAOK1 TAO kinase 1
THBS3 thrombospondin 3
THOC6 THO complex 6
TMEM53 transmembrane protein 53
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TRIM25 tripartite motif containing 25
TTLL1 tubulin tyrosine ligase-like family member 1
TUBG2 tubulin, gamma 2
WDR62 WD repeat domain 62
ZNF205 zinc finger protein 205
ZNF770 zinc finger protein 770
ZNF816 zinc finger protein 816