nicotinic acid-5301 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the nicotinic acid-5301 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADCY9 adenylate cyclase 9
APLP2 amyloid beta (A4) precursor-like protein 2
ARHGAP33 Rho GTPase activating protein 33
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
ASPH aspartate beta-hydroxylase
ATP6V0A1 ATPase, H+ transporting, lysosomal V0 subunit a1
ATP6V1A ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A
BCL9 B-cell CLL/lymphoma 9
CAPN15 calpain 15
CAPRIN1 cell cycle associated protein 1
CEP72 centrosomal protein 72kDa
CHKB choline kinase beta
CIC capicua transcriptional repressor
COMMD4 COMM domain containing 4
CORT cortistatin
CRABP1 cellular retinoic acid binding protein 1
DCAKD dephospho-CoA kinase domain containing
DDX43 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1
EDRF1 erythroid differentiation regulatory factor 1
EIF2AK1 eukaryotic translation initiation factor 2-alpha kinase 1
EML3 echinoderm microtubule associated protein like 3
EPB41L2 erythrocyte membrane protein band 4.1-like 2
EPS15L1 epidermal growth factor receptor pathway substrate 15-like 1
F3 coagulation factor III (thromboplastin, tissue factor)
FZD7 frizzled class receptor 7
GANAB glucosidase, alpha; neutral AB
GDI1 GDP dissociation inhibitor 1
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis)
GOLGA8B golgin A8 family, member B
GOSR2 golgi SNAP receptor complex member 2
GPNMB glycoprotein (transmembrane) nmb
GPR87 G protein-coupled receptor 87
GPRC5C G protein-coupled receptor, class C, group 5, member C
GRSF1 G-rich RNA sequence binding factor 1
GTF2H3 general transcription factor IIH, polypeptide 3, 34kDa
HAUS5 HAUS augmin-like complex, subunit 5
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
HPS1 Hermansky-Pudlak syndrome 1
IKZF5 IKAROS family zinc finger 5 (Pegasus)
ING1 inhibitor of growth family, member 1
INHBA inhibin, beta A
ITSN1 intersectin 1 (SH3 domain protein)
JRK Jrk homolog (mouse)
KHK ketohexokinase (fructokinase)
KLF4 Kruppel-like factor 4 (gut)
KRIT1 KRIT1, ankyrin repeat containing
LRRC49 leucine rich repeat containing 49
LSM4 LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae)
LZTS3 leucine zipper, putative tumor suppressor family member 3
METTL3 methyltransferase like 3
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
MOCS1 molybdenum cofactor synthesis 1
MXD3 MAX dimerization protein 3
NAA40 N(alpha)-acetyltransferase 40, NatD catalytic subunit
NCAPH2 non-SMC condensin II complex, subunit H2
NDUFA5 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5
NDUFB8 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa
NEK3 NIMA-related kinase 3
NFRKB nuclear factor related to kappaB binding protein
NFYA nuclear transcription factor Y, alpha
NME5 NME/NM23 family member 5
NR2F6 nuclear receptor subfamily 2, group F, member 6
NUP160 nucleoporin 160kDa
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
PACS1 phosphofurin acidic cluster sorting protein 1
PACSIN3 protein kinase C and casein kinase substrate in neurons 3
PATZ1 POZ (BTB) and AT hook containing zinc finger 1
PCID2 PCI domain containing 2
PDE4DIP phosphodiesterase 4D interacting protein
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PMS2P3 postmeiotic segregation increased 2 pseudogene 3
RAB6A RAB6A, member RAS oncogene family
RAD51D RAD51 paralog D
RAD54L2 RAD54-like 2 (S. cerevisiae)
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RNF6 ring finger protein (C3H2C3 type) 6
RRP1B ribosomal RNA processing 1B
S100A13 S100 calcium binding protein A13
SATB2 SATB homeobox 2
SHOX2 short stature homeobox 2
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
SNW1 SNW domain containing 1
SPAM1 sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding)
STK11 serine/threonine kinase 11
STK25 serine/threonine kinase 25
STRA6 stimulated by retinoic acid 6
TCF7 transcription factor 7 (T-cell specific, HMG-box)
TEAD3 TEA domain family member 3
TM2D1 TM2 domain containing 1
TPM1 tropomyosin 1 (alpha)
TPST2 tyrosylprotein sulfotransferase 2
TRIM25 tripartite motif containing 25
TRIM66 tripartite motif containing 66
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TTC33 tetratricopeptide repeat domain 33
VAX2 ventral anterior homeobox 2
WWOX WW domain containing oxidoreductase
YKT6 YKT6 v-SNARE homolog (S. cerevisiae)
ZNF701 zinc finger protein 701

decreased expression

Symbol Name
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
ACVR2B activin A receptor, type IIB
ADGRE5 adhesion G protein-coupled receptor E5
ALDOC aldolase C, fructose-bisphosphate
ANKEF1 ankyrin repeat and EF-hand domain containing 1
ARAF A-Raf proto-oncogene, serine/threonine kinase
ATG2A autophagy related 2A
B4GALT2 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
BDH2 3-hydroxybutyrate dehydrogenase, type 2
C14ORF132 chromosome 14 open reading frame 132
C16ORF59 chromosome 16 open reading frame 59
C2ORF42 chromosome 2 open reading frame 42
C7ORF43 chromosome 7 open reading frame 43
CCNT1 cyclin T1
CCZ1B CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae)
CDKL3 cyclin-dependent kinase-like 3
CLDN15 claudin 15
DEAF1 DEAF1 transcription factor
DNAJC13 DnaJ (Hsp40) homolog, subfamily C, member 13
EAF2 ELL associated factor 2
ECHDC3 enoyl CoA hydratase domain containing 3
EDEM2 ER degradation enhancer, mannosidase alpha-like 2
EFHD1 EF-hand domain family, member D1
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
EXTL2 exostosin-like glycosyltransferase 2
FAM114A1 family with sequence similarity 114, member A1
FBXO46 F-box protein 46
FIP1L1 factor interacting with PAPOLA and CPSF1
FSD1 fibronectin type III and SPRY domain containing 1
FYCO1 FYVE and coiled-coil domain containing 1
FZD4 frizzled class receptor 4
GAN gigaxonin
GBP2 guanylate binding protein 2, interferon-inducible
GFOD1 glucose-fructose oxidoreductase domain containing 1
GFOD2 glucose-fructose oxidoreductase domain containing 2
GLS2 glutaminase 2 (liver, mitochondrial)
GRAMD4 GRAM domain containing 4
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
HAUS2 HAUS augmin-like complex, subunit 2
IL17RB interleukin 17 receptor B
KIF13B kinesin family member 13B
KIZ kizuna centrosomal protein
KLF7 Kruppel-like factor 7 (ubiquitous)
LCP1 lymphocyte cytosolic protein 1 (L-plastin)
LINC00115 long intergenic non-protein coding RNA 115
LYPLA2P1 lysophospholipase II pseudogene 1
MAPK12 mitogen-activated protein kinase 12
MAPKBP1 mitogen-activated protein kinase binding protein 1
MB myoglobin
MEIS3P1 Meis homeobox 3 pseudogene 1
NAA50 N(alpha)-acetyltransferase 50, NatE catalytic subunit
NUDT13 nudix (nucleoside diphosphate linked moiety X)-type motif 13
PGP phosphoglycolate phosphatase
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PLEKHO1 pleckstrin homology domain containing, family O member 1
PPIP5K1 diphosphoinositol pentakisphosphate kinase 1
PRPH peripherin
PRSS22 protease, serine, 22
PSTPIP2 proline-serine-threonine phosphatase interacting protein 2
PUS7L pseudouridylate synthase 7 homolog (S. cerevisiae)-like
RAB33B RAB33B, member RAS oncogene family
RBM42 RNA binding motif protein 42
RFTN1 raftlin, lipid raft linker 1
RPL23AP7 ribosomal protein L23a pseudogene 7
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SHARPIN SHANK-associated RH domain interactor
SLC12A7 solute carrier family 12 (potassium/chloride transporter), member 7
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5
SLC35F5 solute carrier family 35, member F5
SLC39A7 solute carrier family 39 (zinc transporter), member 7
SNX10 sorting nexin 10
SOX12 SRY (sex determining region Y)-box 12
SREK1IP1 SREK1-interacting protein 1
STAG3L1 stromal antigen 3-like 1 (pseudogene)
SUN2 Sad1 and UNC84 domain containing 2
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TARBP1 TAR (HIV-1) RNA binding protein 1
TMC7 transmembrane channel-like 7
TRAPPC12 trafficking protein particle complex 12
TUBA3C tubulin, alpha 3c
UBQLN4 ubiquilin 4
VEGFC vascular endothelial growth factor C
VGF VGF nerve growth factor inducible
WARS2 tryptophanyl tRNA synthetase 2, mitochondrial
XK X-linked Kx blood group
ZBED1 zinc finger, BED-type containing 1
ZC3H3 zinc finger CCCH-type containing 3
ZNF141 zinc finger protein 141
ZNF184 zinc finger protein 184
ZNF219 zinc finger protein 219
ZNF35 zinc finger protein 35
ZNF432 zinc finger protein 432
ZNF639 zinc finger protein 639
ZNF787 zinc finger protein 787
ZNF862 zinc finger protein 862
ZNHIT2 zinc finger, HIT-type containing 2