nialamide-4525 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

200 genes differentially expressed following the nialamide-4525 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACOT11 acyl-CoA thioesterase 11
ACOX3 acyl-CoA oxidase 3, pristanoyl
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AKR1C2 aldo-keto reductase family 1, member C2
AKT3 v-akt murine thymoma viral oncogene homolog 3
ATP6V0A2 ATPase, H+ transporting, lysosomal V0 subunit a2
BATF basic leucine zipper transcription factor, ATF-like
BICD1 bicaudal D homolog 1 (Drosophila)
C14ORF93 chromosome 14 open reading frame 93
CACNA1G calcium channel, voltage-dependent, T type, alpha 1G subunit
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CEMP1 cementum protein 1
CISH cytokine inducible SH2-containing protein
CLCN7 chloride channel, voltage-sensitive 7
COL1A2 collagen, type I, alpha 2
CST4 cystatin S
CTDSPL CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
CYP2W1 cytochrome P450, family 2, subfamily W, polypeptide 1
DLX2 distal-less homeobox 2
EFR3B EFR3 homolog B (S. cerevisiae)
ELAC2 elaC ribonuclease Z 2
EMID1 EMI domain containing 1
ENOX2 ecto-NOX disulfide-thiol exchanger 2
ESRRG estrogen-related receptor gamma
F5 coagulation factor V (proaccelerin, labile factor)
FAM13C family with sequence similarity 13, member C
FCAR Fc fragment of IgA receptor
FGF5 fibroblast growth factor 5
FLJ11292
FOXL1 forkhead box L1
GADD45GIP1 growth arrest and DNA-damage-inducible, gamma interacting protein 1
GIF gastric intrinsic factor (vitamin B synthesis)
GMPR guanosine monophosphate reductase
GSK3A glycogen synthase kinase 3 alpha
HEMK1 HemK methyltransferase family member 1
HPS1 Hermansky-Pudlak syndrome 1
HSD17B6 hydroxysteroid (17-beta) dehydrogenase 6
ICA1 islet cell autoantigen 1, 69kDa
IFFO1 intermediate filament family orphan 1
IL1R1 interleukin 1 receptor, type I
IL1RL1 interleukin 1 receptor-like 1
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
ITGA8 integrin, alpha 8
KCNJ12 potassium channel, inwardly rectifying subfamily J, member 12
KHDRBS2 KH domain containing, RNA binding, signal transduction associated 2
KIF5C kinesin family member 5C
LEFTY1 left-right determination factor 1
LRP1 low density lipoprotein receptor-related protein 1
LRP4 low density lipoprotein receptor-related protein 4
LY9 lymphocyte antigen 9
MEF2D myocyte enhancer factor 2D
MON2 MON2 homolog (S. cerevisiae)
MRPL41 mitochondrial ribosomal protein L41
MYCNOS MYCN opposite strand
MYOC myocilin, trabecular meshwork inducible glucocorticoid response
NCAM2 neural cell adhesion molecule 2
NCR2 natural cytotoxicity triggering receptor 2
NIPSNAP3B nipsnap homolog 3B (C. elegans)
NRL neural retina leucine zipper
PAOX polyamine oxidase (exo-N4-amino)
PDE3B phosphodiesterase 3B, cGMP-inhibited
PDE4C phosphodiesterase 4C, cAMP-specific
PDGFRB platelet-derived growth factor receptor, beta polypeptide
PDIA2 protein disulfide isomerase family A, member 2
PDPR pyruvate dehydrogenase phosphatase regulatory subunit
PGF placental growth factor
PIK3R4 phosphoinositide-3-kinase, regulatory subunit 4
PIWIL2 piwi-like RNA-mediated gene silencing 2
PPP4R4 protein phosphatase 4, regulatory subunit 4
PRKACG protein kinase, cAMP-dependent, catalytic, gamma
PRLR prolactin receptor
PTP4A3 protein tyrosine phosphatase type IVA, member 3
RAB6A RAB6A, member RAS oncogene family
RAP1GAP RAP1 GTPase activating protein
RASA3 RAS p21 protein activator 3
RBM12B-AS1 RBM12B antisense RNA 1
RGS12 regulator of G-protein signaling 12
RGS6 regulator of G-protein signaling 6
SCN11A sodium channel, voltage gated, type XI alpha subunit
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC48A1 solute carrier family 48 (heme transporter), member 1
SNAPC4 small nuclear RNA activating complex, polypeptide 4, 190kDa
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SNRPN small nuclear ribonucleoprotein polypeptide N
SP1 Sp1 transcription factor
SPOCK3 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
TADA3 transcriptional adaptor 3
TBCD tubulin folding cofactor D
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TLL2 tolloid-like 2
TONSL tonsoku-like, DNA repair protein
TRD T cell receptor delta locus
TRIM29 tripartite motif containing 29
VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1)
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2)
VCAN versican
WAS Wiskott-Aldrich syndrome
XAF1 XIAP associated factor 1

decreased expression

Symbol Name
ACAD10 acyl-CoA dehydrogenase family, member 10
ACBD4 acyl-CoA binding domain containing 4
ANXA2P3 annexin A2 pseudogene 3
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
ATXN2 ataxin 2
BAAT bile acid CoA:amino acid N-acyltransferase
BTF3P12 basic transcription factor 3 pseudogene 12
C17ORF70 chromosome 17 open reading frame 70
C1ORF35 chromosome 1 open reading frame 35
CCNA1 cyclin A1
CDADC1 cytidine and dCMP deaminase domain containing 1
CDC37L1 cell division cycle 37-like 1
CDK3 cyclin-dependent kinase 3
CLCN5 chloride channel, voltage-sensitive 5
CLIP4 CAP-GLY domain containing linker protein family, member 4
CORO1A coronin, actin binding protein, 1A
CPED1 cadherin-like and PC-esterase domain containing 1
CPNE7 copine VII
CPPED1 calcineurin-like phosphoesterase domain containing 1
CUZD1 CUB and zona pellucida-like domains 1
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1
EFNA3 ephrin-A3
EFNB1 ephrin-B1
ERCC2 excision repair cross-complementation group 2
FAM53B family with sequence similarity 53, member B
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FKBP10 FK506 binding protein 10, 65 kDa
FOXN2 forkhead box N2
GLS2 glutaminase 2 (liver, mitochondrial)
GNA14 guanine nucleotide binding protein (G protein), alpha 14
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
H1F0 H1 histone family, member 0
HIST1H2BO histone cluster 1, H2bo
HIST1H4E histone cluster 1, H4e
HOXA7 homeobox A7
HYMAI hydatidiform mole associated and imprinted (non-protein coding)
IKZF5 IKAROS family zinc finger 5 (Pegasus)
INF2 inverted formin, FH2 and WH2 domain containing
IREB2 iron-responsive element binding protein 2
KIFC1 kinesin family member C1
KLF3 Kruppel-like factor 3 (basic)
KRT6A keratin 6A, type II
KRT8P12 keratin 8 pseudogene 12
LMNB1 lamin B1
MTMR11 myotubularin related protein 11
NBEAL2 neurobeachin-like 2
NDP Norrie disease (pseudoglioma)
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NPM3 nucleophosmin/nucleoplasmin 3
NT5M 5',3'-nucleotidase, mitochondrial
NXPH4 neurexophilin 4
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PAIP2B poly(A) binding protein interacting protein 2B
PARM1 prostate androgen-regulated mucin-like protein 1
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime
PID1 phosphotyrosine interaction domain containing 1
POM121 POM121 transmembrane nucleoporin
PPIP5K1 diphosphoinositol pentakisphosphate kinase 1
PPP2R3B protein phosphatase 2, regulatory subunit B'', beta
PRSS8 protease, serine, 8
RAB33B RAB33B, member RAS oncogene family
RAB3A RAB3A, member RAS oncogene family
RARS arginyl-tRNA synthetase
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
RIN1 Ras and Rab interactor 1
RNF122 ring finger protein 122
SCIN scinderin
SEC14L2 SEC14-like 2 (S. cerevisiae)
SETD8 SET domain containing (lysine methyltransferase) 8
SETMAR SET domain and mariner transposase fusion gene
SLC16A10 solute carrier family 16 (aromatic amino acid transporter), member 10
SLC25A10 solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
SLC39A7 solute carrier family 39 (zinc transporter), member 7
SLC46A3 solute carrier family 46, member 3
SLMO1 slowmo homolog 1 (Drosophila)
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SPRYD7 SPRY domain containing 7
STAG3 stromal antigen 3
STK16 serine/threonine kinase 16
SYT17 synaptotagmin XVII
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TEP1 telomerase-associated protein 1
TMEM132A transmembrane protein 132A
TMEM2 transmembrane protein 2
TMEM62 transmembrane protein 62
TNFRSF8 tumor necrosis factor receptor superfamily, member 8
TOLLIP toll interacting protein
TRAPPC13 trafficking protein particle complex 13
TRAPPC6A trafficking protein particle complex 6A
UGT8 UDP glycosyltransferase 8
USP19 ubiquitin specific peptidase 19
WDR33 WD repeat domain 33
YOD1 YOD1 deubiquitinase
ZBTB22 zinc finger and BTB domain containing 22
ZBTB44 zinc finger and BTB domain containing 44
ZMAT3 zinc finger, matrin-type 3
ZNF442 zinc finger protein 442
ZNF768 zinc finger protein 768