netilmicin-7302 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the netilmicin-7302 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACADSB acyl-CoA dehydrogenase, short/branched chain
ALDOB aldolase B, fructose-bisphosphate
AQP7 aquaporin 7
ASTN2 astrotactin 2
AURKC aurora kinase C
AVL9 AVL9 homolog (S. cerevisiase)
CA9 carbonic anhydrase IX
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
CALHM2 calcium homeostasis modulator 2
CD80 CD80 molecule
CDC14B cell division cycle 14B
CDK20 cyclin-dependent kinase 20
CDK3 cyclin-dependent kinase 3
CHN2 chimerin 2
CTNND2 catenin (cadherin-associated protein), delta 2
CXCR2 chemokine (C-X-C motif) receptor 2
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
DHRS9 dehydrogenase/reductase (SDR family) member 9
DNAH7 dynein, axonemal, heavy chain 7
DNAJB5 DnaJ (Hsp40) homolog, subfamily B, member 5
DRD2 dopamine receptor D2
DST dystonin
DSTYK dual serine/threonine and tyrosine protein kinase
EGFR epidermal growth factor receptor
EHMT2 euchromatic histone-lysine N-methyltransferase 2
ETV1 ets variant 1
FKBP10 FK506 binding protein 10, 65 kDa
FLJ21369 uncharacterized protein FLJ21369
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2
GLP1R glucagon-like peptide 1 receptor
GOLGA2 golgin A2
GPM6B glycoprotein M6B
GPR17 G protein-coupled receptor 17
GPR176 G protein-coupled receptor 176
HOOK1 hook microtubule-tethering protein 1
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HYAL3 hyaluronoglucosaminidase 3
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
INO80D INO80 complex subunit D
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KCTD13 potassium channel tetramerization domain containing 13
KLF4 Kruppel-like factor 4 (gut)
LMNA lamin A/C
LRP3 low density lipoprotein receptor-related protein 3
MBL1P mannose-binding lectin (protein A) 1, pseudogene
MFAP3 microfibrillar-associated protein 3
MGAT2 mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
MTSS1L metastasis suppressor 1-like
NCAPH2 non-SMC condensin II complex, subunit H2
NCOA2 nuclear receptor coactivator 2
NNMT nicotinamide N-methyltransferase
NOP14-AS1 NOP14 antisense RNA 1
NPM3 nucleophosmin/nucleoplasmin 3
NTSR1 neurotensin receptor 1 (high affinity)
OVGP1 oviductal glycoprotein 1, 120kDa
PAQR6 progestin and adipoQ receptor family member VI
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PCSK6 proprotein convertase subtilisin/kexin type 6
PCYT1A phosphate cytidylyltransferase 1, choline, alpha
PDGFB platelet-derived growth factor beta polypeptide
PEX26 peroxisomal biogenesis factor 26
PHLDB1 pleckstrin homology-like domain, family B, member 1
PHOX2A paired-like homeobox 2a
PLIN2 perilipin 2
POMT2 protein-O-mannosyltransferase 2
PRB1 proline-rich protein BstNI subfamily 1
PRR4 proline rich 4 (lacrimal)
PRR7 proline rich 7 (synaptic)
PTK6 protein tyrosine kinase 6
PTPRU protein tyrosine phosphatase, receptor type, U
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RANBP1 RAN binding protein 1
RNF6 ring finger protein (C3H2C3 type) 6
RRAGB Ras-related GTP binding B
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae)
RTEL1 regulator of telomere elongation helicase 1
SBNO2 strawberry notch homolog 2 (Drosophila)
SCG5 secretogranin V
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4
SNRNP200 small nuclear ribonucleoprotein 200kDa (U5)
TAAR5 trace amine associated receptor 5
TCF4 transcription factor 4
TGFB2 transforming growth factor, beta 2
TJAP1 tight junction associated protein 1 (peripheral)
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TSSK2 testis-specific serine kinase 2
TUBA4B tubulin, alpha 4b
TXLNG taxilin gamma
VAV2 vav 2 guanine nucleotide exchange factor
VAV3 vav 3 guanine nucleotide exchange factor
VN1R1 vomeronasal 1 receptor 1
WDR25 WD repeat domain 25
WDR33 WD repeat domain 33
YIPF2 Yip1 domain family, member 2
ZNF10 zinc finger protein 10
ZNF639 zinc finger protein 639

decreased expression

Symbol Name
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
AEN apoptosis enhancing nuclease
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
ANKRD40 ankyrin repeat domain 40
AP1AR adaptor-related protein complex 1 associated regulatory protein
ARGLU1 arginine and glutamate rich 1
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
AXIN1 axin 1
BBS7 Bardet-Biedl syndrome 7
BCKDHA branched chain keto acid dehydrogenase E1, alpha polypeptide
BCORL1 BCL6 corepressor-like 1
BPHL biphenyl hydrolase-like (serine hydrolase)
C10ORF88 chromosome 10 open reading frame 88
C17ORF75 chromosome 17 open reading frame 75
C1ORF115 chromosome 1 open reading frame 115
C6ORF47 chromosome 6 open reading frame 47
C8ORF60 chromosome 8 open reading frame 60
C9ORF114 chromosome 9 open reading frame 114
CAPN5 calpain 5
CARD8 caspase recruitment domain family, member 8
CCDC85C coiled-coil domain containing 85C
CCNJ cyclin J
CCNJL cyclin J-like
CCP110 centriolar coiled coil protein 110kDa
CENPO centromere protein O
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11
CLEC16A C-type lectin domain family 16, member A
CNKSR1 connector enhancer of kinase suppressor of Ras 1
COCH cochlin
COQ4 coenzyme Q4
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
DCUN1D2 DCN1, defective in cullin neddylation 1, domain containing 2
DLK1 delta-like 1 homolog (Drosophila)
DNAJC24 DnaJ (Hsp40) homolog, subfamily C, member 24
EFNA3 ephrin-A3
EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase
ELOVL4 ELOVL fatty acid elongase 4
ETNK2 ethanolamine kinase 2
F3 coagulation factor III (thromboplastin, tissue factor)
FAM222B family with sequence similarity 222, member B
FAM50B family with sequence similarity 50, member B
FAM53B family with sequence similarity 53, member B
FBXL4 F-box and leucine-rich repeat protein 4
FBXL6 F-box and leucine-rich repeat protein 6
FBXO2 F-box protein 2
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FYCO1 FYVE and coiled-coil domain containing 1
GALNS galactosamine (N-acetyl)-6-sulfatase
HLX H2.0-like homeobox
HSD3B2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2
IPPK inositol 1,3,4,5,6-pentakisphosphate 2-kinase
KIAA0319L KIAA0319-like
KIRREL kin of IRRE like (Drosophila)
MANBA mannosidase, beta A, lysosomal
MMP13 matrix metallopeptidase 13
MNX1 motor neuron and pancreas homeobox 1
MVP major vault protein
NARFL nuclear prelamin A recognition factor-like
NSD1 nuclear receptor binding SET domain protein 1
NT5DC3 5'-nucleotidase domain containing 3
ONECUT2 one cut homeobox 2
PCSK7 proprotein convertase subtilisin/kexin type 7
PEG3 paternally expressed 3
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1
PRICKLE3 prickle homolog 3 (Drosophila)
PRMT7 protein arginine methyltransferase 7
QTRT1 queuine tRNA-ribosyltransferase 1
RAB3A RAB3A, member RAS oncogene family
RGS20 regulator of G-protein signaling 20
RNF125 ring finger protein 125, E3 ubiquitin protein ligase
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SH3GLB2 SH3-domain GRB2-like endophilin B2
SIRT7 sirtuin 7
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SNHG20 small nucleolar RNA host gene 20
ST6GALNAC4 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4
STAR steroidogenic acute regulatory protein
STBD1 starch binding domain 1
TBXAS1 thromboxane A synthase 1 (platelet)
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast)
TMA16 translation machinery associated 16 homolog (S. cerevisiae)
TMEM132A transmembrane protein 132A
TNFSF12 tumor necrosis factor (ligand) superfamily, member 12
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
USB1 U6 snRNA biogenesis 1
VEZT vezatin, adherens junctions transmembrane protein
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
VPS8 vacuolar protein sorting 8 homolog (S. cerevisiae)
XPA xeroderma pigmentosum, complementation group A
ZAK sterile alpha motif and leucine zipper containing kinase AZK
ZKSCAN3 zinc finger with KRAB and SCAN domains 3
ZNF107 zinc finger protein 107
ZNF165 zinc finger protein 165
ZNF197 zinc finger protein 197
ZNF230 zinc finger protein 230
ZNF552 zinc finger protein 552
ZNF623 zinc finger protein 623
ZNF668 zinc finger protein 668
ZNF787 zinc finger protein 787