nervous system cancer Gene Set

Dataset GWASdb SNP-Disease Associations
Category disease or phenotype associations
Type disease
Description An organ system cancer located_in the nervous sytem that affects the central or peripheral nervous system. (Human Disease Ontology, DOID_3093)
External Link http://jjwanglab.org/gwasdb/gwasdb2/gwasdb2/go_trait/DOID:3093
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Genes

95 genes associated with the disease nervous system cancer in GWAS and other genetic association datasets from the GWASdb SNP-Disease Associations dataset.

Symbol Name Standardized Value
BARD1 BRCA1 associated RING domain 1 1.14143
TERT telomerase reverse transcriptase 1.11765
CASC15 cancer susceptibility candidate 15 (non-protein coding) 1.06726
CDKN2B-AS1 CDKN2B antisense RNA 1 0.987416
LMO1 LIM domain only 1 (rhombotin 1) 0.987416
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) 0.898897
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 0.843628
SLC25A24 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24 0.696165
RTEL1 regulator of telomere elongation helicase 1 0.636886
HACE1 HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1 0.583815
PHLDB1 pleckstrin homology-like domain, family B, member 1 0.570922
LRP1B low density lipoprotein receptor-related protein 1B 0.491521
HSD17B12 hydroxysteroid (17-beta) dehydrogenase 12 0.484808
KIF26B kinesin family member 26B 0.479741
SHANK2 SH3 and multiple ankyrin repeat domains 2 0.478437
LIN28B lin-28 homolog B (C. elegans) 0.477278
SMYD3 SET and MYND domain containing 3 0.469423
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 0.468977
SLC35A3 solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 0.46551
EGFR epidermal growth factor receptor 0.464584
DBT dihydrolipoamide branched chain transacylase E2 0.458853
RSRC1 arginine/serine-rich coiled-coil 1 0.451059
TRAF5 TNF receptor-associated factor 5 0.448164
CPZ carboxypeptidase Z 0.44542
XPO4 exportin 4 0.444955
DDX4 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 0.443826
ACOT11 acyl-CoA thioesterase 11 0.441337
SSBP2 single-stranded DNA binding protein 2 0.438494
IKZF1 IKAROS family zinc finger 1 (Ikaros) 0.434385
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent) 0.429745
MIR205HG MIR205 host gene 0.426003
CALCOCO2 calcium binding and coiled-coil domain 2 0.421723
KAZN kazrin, periplakin interacting protein 0.419831
IL31RA interleukin 31 receptor A 0.419831
DNAH7 dynein, axonemal, heavy chain 7 0.41973
LRRC69 leucine rich repeat containing 69 0.418905
TIAM1 T-cell lymphoma invasion and metastasis 1 0.417982
ABCA12 ATP-binding cassette, sub-family A (ABC1), member 12 0.417528
CCDC23 coiled-coil domain containing 23 0.410372
RLF rearranged L-myc fusion 0.408812
MORC3 MORC family CW-type zinc finger 3 0.407725
STIM2 stromal interaction molecule 2 0.400651
PLD5 phospholipase D family, member 5 0.400489
SLC39A10 solute carrier family 39 (zinc transporter), member 10 0.399857
HIAT1 hippocampus abundant transcript 1 0.396908
DRD1 dopamine receptor D1 0.396251
TRMT13 tRNA methyltransferase 13 homolog (S. cerevisiae) 0.395481
SPHKAP SPHK1 interactor, AKAP domain containing 0.394614
JARID2 jumonji, AT rich interactive domain 2 0.394164
STK4 serine/threonine kinase 4 0.393975
PEX14 peroxisomal biogenesis factor 14 0.39242
SASS6 spindle assembly 6 homolog (C. elegans) 0.392363
RPRD2 regulation of nuclear pre-mRNA domain containing 2 0.391637
NXPH1 neurexophilin 1 0.391153
SKIV2L superkiller viralicidic activity 2-like (S. cerevisiae) 0.388873
NR5A2 nuclear receptor subfamily 5, group A, member 2 0.388873
PNLIP pancreatic lipase 0.388734
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4 0.388415
GLCCI1 glucocorticoid induced 1 0.387239
ATF6 activating transcription factor 6 0.385867
NRSN1 neurensin 1 0.385072
NKAIN3 Na+/K+ transporting ATPase interacting 3 0.385035
UGT1A10 UDP glucuronosyltransferase 1 family, polypeptide A10 0.384888
IRF4 interferon regulatory factor 4 0.384332
TOX thymocyte selection-associated high mobility group box 0.383673
SH3YL1 SH3 and SYLF domain containing 1 0.38253
OR2M7 olfactory receptor, family 2, subfamily M, member 7 0.381759
ABCC13 ATP-binding cassette, sub-family C (CFTR/MRP), member 13, pseudogene 0.38142
SLC22A18AS solute carrier family 22 (organic cation transporter), member 18 antisense 0.381319
MAMDC2 MAM domain containing 2 0.381219
LOC285768 uncharacterized LOC285768 0.380889
LEPR leptin receptor 0.380758
DDAH1 dimethylarginine dimethylaminohydrolase 1 0.380341
SDK1 sidekick cell adhesion molecule 1 0.380214
KCTD10 potassium channel tetramerization domain containing 10 0.380183
MED13L mediator complex subunit 13-like 0.379964
PARD3B par-3 family cell polarity regulator beta 0.379503
KCNK10 potassium channel, two pore domain subfamily K, member 10 0.379382
MMAB methylmalonic aciduria (cobalamin deficiency) cblB type 0.378965
ANKAR ankyrin and armadillo repeat containing 0.378329
SLC38A9 solute carrier family 38, member 9 0.377935
UBE3B ubiquitin protein ligase E3B 0.377686
ARHGAP26 Rho GTPase activating protein 26 0.377659
TTLL6 tubulin tyrosine ligase-like family member 6 0.375884
SFTA3 surfactant associated 3 0.37501
VWA3B von Willebrand factor A domain containing 3B 0.374041
PMS1 PMS1 postmeiotic segregation increased 1 (S. cerevisiae) 0.374041
DLGAP1 discs, large (Drosophila) homolog-associated protein 1 0.373974
SRBD1 S1 RNA binding domain 1 0.37338
PLSCR3 phospholipid scramblase 3 0.373037
MSRA methionine sulfoxide reductase A 0.372451
EXT1 exostosin glycosyltransferase 1 0.372349
SPP2 secreted phosphoprotein 2, 24kDa 0.372328
MVK mevalonate kinase 0.371825
DGKI diacylglycerol kinase, iota 0.371568