neoplasm of the gastrointestinal tract Gene Set

Dataset HPO Gene-Disease Associations
Category disease or phenotype associations
Type phenotype
Description A tumor (abnormal growth of tissue) of the gastrointestinal tract. (Human Phenotype Ontology, HP_0007378)
External Link http://compbio.charite.de/hpoweb/showterm?id=HP:0007378
Similar Terms
Downloads & Tools

Genes

129 genes associated with the neoplasm of the gastrointestinal tract phenotype by mapping known disease genes to disease phenotypes from the HPO Gene-Disease Associations dataset.

Symbol Name
AAGAB alpha- and gamma-adaptin binding protein
ABCB11 ATP-binding cassette, sub-family B (MDR/TAP), member 11
ACVRL1 activin A receptor type II-like 1
AKT1 v-akt murine thymoma viral oncogene homolog 1
APC adenomatous polyposis coli
ASCC1 activating signal cointegrator 1 complex subunit 1
AXIN1 axin 1
AXIN2 axin 2
BAX BCL2-associated X protein
BLM Bloom syndrome, RecQ helicase-like
BMPR1A bone morphogenetic protein receptor, type IA
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B
BUB3 BUB3 mitotic checkpoint protein
CASP10 caspase 10, apoptosis-related cysteine peptidase
CASP8 caspase 8, apoptosis-related cysteine peptidase
CC2D2A coiled-coil and C2 domain containing 2A
CD19 CD19 molecule
CD81 CD81 molecule
CDK4 cyclin-dependent kinase 4
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CDKN2A cyclin-dependent kinase inhibitor 2A
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CEP57 centrosomal protein 57kDa
CHEK2 checkpoint kinase 2
COL14A1 collagen, type XIV, alpha 1
CR2 complement component (3d/Epstein Barr virus) receptor 2
CTHRC1 collagen triple helix repeat containing 1
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
DCC DCC netrin 1 receptor
DIS3L2 DIS3 like 3'-5' exoribonuclease 2
DNASE1L3 deoxyribonuclease I-like 3
ECE1 endothelin converting enzyme 1
EDN3 endothelin 3
EDNRB endothelin receptor type B
ENG endoglin
EP300 E1A binding protein p300
EPCAM epithelial cell adhesion molecule
ERBB2 erb-b2 receptor tyrosine kinase 2
EWSR1 EWS RNA-binding protein 1
FAH fumarylacetoacetate hydrolase (fumarylacetoacetase)
FGFR2 fibroblast growth factor receptor 2
FGFR3 fibroblast growth factor receptor 3
FH fumarate hydratase
FLCN folliculin
G6PC glucose-6-phosphatase, catalytic subunit
GDF2 growth differentiation factor 2
GDNF glial cell derived neurotrophic factor
GNAS GNAS complex locus
GPC3 glypican 3
GPC4 glypican 4
GREM1 gremlin 1, DAN family BMP antagonist
H19 H19, imprinted maternally expressed transcript (non-protein coding)
HBB hemoglobin, beta
HFE hemochromatosis
HMBS hydroxymethylbilane synthase
HNF1A HNF1 homeobox A
ICOS inducible T-cell co-stimulator
IGF2R insulin-like growth factor 2 receptor
INPP5E inositol polyphosphate-5-phosphatase, 72 kDa
IRF1 interferon regulatory factor 1
JAG1 jagged 1
KCNQ1OT1 KCNQ1 opposite strand/antisense transcript 1 (non-protein coding)
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KLF6 Kruppel-like factor 6
KLLN killin, p53-regulated DNA replication inhibitor
KRAS Kirsten rat sarcoma viral oncogene homolog
L1CAM L1 cell adhesion molecule
LRBA LPS-responsive vesicle trafficking, beach and anchor containing
LRRFIP2 leucine rich repeat (in FLII) interacting protein 2
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MCC mutated in colorectal cancers
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MEN1 multiple endocrine neoplasia I
MET MET proto-oncogene, receptor tyrosine kinase
MLH1 mutL homolog 1
MLH3 mutL homolog 3
MS4A1 membrane-spanning 4-domains, subfamily A, member 1
MSH2 mutS homolog 2
MSH6 mutS homolog 6
MSR1 macrophage scavenger receptor 1
MUTYH mutY homolog
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
NRTN neurturin
NSD1 nuclear receptor binding SET domain protein 1
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PDGFRL platelet-derived growth factor receptor-like
PIEZO2 piezo-type mechanosensitive ion channel component 2
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PMS1 PMS1 postmeiotic segregation increased 1 (S. cerevisiae)
PMS2 PMS2 postmeiotic segregation increased 2 (S. cerevisiae)
POT1 protection of telomeres 1
POU6F2 POU class 6 homeobox 2
PRKCD protein kinase C, delta
PTCH1 patched 1
PTCH2 patched 2
PTEN phosphatase and tensin homolog
PTPN12 protein tyrosine phosphatase, non-receptor type 12
PTPN3 protein tyrosine phosphatase, non-receptor type 3
PTPRJ protein tyrosine phosphatase, receptor type, J
RAD54B RAD54 homolog B (S. cerevisiae)
RET ret proto-oncogene
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
RPGRIP1L RPGRIP1-like
RPS19 ribosomal protein S19
SDHA succinate dehydrogenase complex, subunit A, flavoprotein (Fp)
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
SDHC succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa
SDHD succinate dehydrogenase complex, subunit D, integral membrane protein
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SETBP1 SET binding protein 1
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4
SMAD4 SMAD family member 4
STK11 serine/threonine kinase 11
SUFU suppressor of fused homolog (Drosophila)
TERT telomerase reverse transcriptase
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TMEM67 transmembrane protein 67
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B
TNFRSF13C tumor necrosis factor receptor superfamily, member 13C
TNFSF12 tumor necrosis factor (ligand) superfamily, member 12
TP53 tumor protein p53
TREX1 three prime repair exonuclease 1
UROD uroporphyrinogen decarboxylase
WRN Werner syndrome, RecQ helicase-like
WT1 Wilms tumor 1