neomycin-7221 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the neomycin-7221 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAM3A ADAM metallopeptidase domain 3A (pseudogene)
AFF3 AF4/FMR2 family, member 3
ALDH7A1 aldehyde dehydrogenase 7 family, member A1
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
ART1 ADP-ribosyltransferase 1
ATP6V1B1 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1
BTBD7 BTB (POZ) domain containing 7
C22ORF46 chromosome 22 open reading frame 46
CAMSAP1 calmodulin regulated spectrin-associated protein 1
CCDC64 coiled-coil domain containing 64
CCK cholecystokinin
CDC25C cell division cycle 25C
CEACAM3 carcinoembryonic antigen-related cell adhesion molecule 3
CES3 carboxylesterase 3
CHRNA6 cholinergic receptor, nicotinic, alpha 6 (neuronal)
CLDN17 claudin 17
CREBZF CREB/ATF bZIP transcription factor
CSHL1 chorionic somatomammotropin hormone-like 1
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1
DAGLA diacylglycerol lipase, alpha
DAPK2 death-associated protein kinase 2
DIO2 deiodinase, iodothyronine, type II
DOK4 docking protein 4
EPYC epiphycan
FAM110B family with sequence similarity 110, member B
FGD1 FYVE, RhoGEF and PH domain containing 1
FGFR2 fibroblast growth factor receptor 2
GPR137 G protein-coupled receptor 137
GPR68 G protein-coupled receptor 68
GRM1 glutamate receptor, metabotropic 1
GRM8 glutamate receptor, metabotropic 8
HCN2 hyperpolarization activated cyclic nucleotide gated potassium channel 2
HLA-DRB6 major histocompatibility complex, class II, DR beta 6 (pseudogene)
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)
HOXA2 homeobox A2
HOXB1 homeobox B1
HR hair growth associated
HSPG2 heparan sulfate proteoglycan 2
IL12B interleukin 12B
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5
KDM4C lysine (K)-specific demethylase 4C
KHSRP KH-type splicing regulatory protein
KITLG KIT ligand
KRT19P2 keratin 19 pseudogene 2
LLPH LLP homolog, long-term synaptic facilitation (Aplysia)
MAGEA3 melanoma antigen family A3
MAOA monoamine oxidase A
MAPK14 mitogen-activated protein kinase 14
MAPRE3 microtubule-associated protein, RP/EB family, member 3
MDM4 MDM4, p53 regulator
MED16 mediator complex subunit 16
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4
MSI1 musashi RNA-binding protein 1
MST1 macrophage stimulating 1
MTHFD2L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like
MTMR7 myotubularin related protein 7
MZF1 myeloid zinc finger 1
NADK NAD kinase
NEFM neurofilament, medium polypeptide
NF1 neurofibromin 1
NUDC nudC nuclear distribution protein
OR1D2 olfactory receptor, family 1, subfamily D, member 2
P2RY1 purinergic receptor P2Y, G-protein coupled, 1
PAK4 p21 protein (Cdc42/Rac)-activated kinase 4
PGLYRP1 peptidoglycan recognition protein 1
PLK4 polo-like kinase 4
POM121L2 POM121 transmembrane nucleoporin-like 2
PPARD peroxisome proliferator-activated receptor delta
PRB1 proline-rich protein BstNI subfamily 1
PRDM16 PR domain containing 16
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
RECQL5 RecQ protein-like 5
RGS10 regulator of G-protein signaling 10
RUNX1 runt-related transcription factor 1
SDC3 syndecan 3
SERGEF secretion regulating guanine nucleotide exchange factor
SLC13A3 solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3
SLC44A1 solute carrier family 44 (choline transporter), member 1
SLC6A9 solute carrier family 6 (neurotransmitter transporter, glycine), member 9
SNAP25 synaptosomal-associated protein, 25kDa
SNCG synuclein, gamma (breast cancer-specific protein 1)
SPAM1 sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding)
SPATA1 spermatogenesis associated 1
STXBP6 syntaxin binding protein 6 (amisyn)
TACR1 tachykinin receptor 1
TFF2 trefoil factor 2
TM2D1 TM2 domain containing 1
TMEM212 transmembrane protein 212
TRDMT1 tRNA aspartic acid methyltransferase 1
TREX1 three prime repair exonuclease 1
TRPC3 transient receptor potential cation channel, subfamily C, member 3
UBOX5 U-box domain containing 5
VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1)
WBP5 WW domain binding protein 5
WDFY3 WD repeat and FYVE domain containing 3
ZNF230 zinc finger protein 230
ZNF701 zinc finger protein 701

decreased expression

Symbol Name
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
ADRA2C adrenoceptor alpha 2C
ANKZF1 ankyrin repeat and zinc finger domain containing 1
ANXA2P3 annexin A2 pseudogene 3
ASCC1 activating signal cointegrator 1 complex subunit 1
ASPHD1 aspartate beta-hydroxylase domain containing 1
ATAD3A ATPase family, AAA domain containing 3A
B4GALT2 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
C10ORF88 chromosome 10 open reading frame 88
C19ORF40 chromosome 19 open reading frame 40
C1ORF109 chromosome 1 open reading frame 109
C5ORF45 chromosome 5 open reading frame 45
C9ORF114 chromosome 9 open reading frame 114
CADPS2 Ca++-dependent secretion activator 2
CAMKMT calmodulin-lysine N-methyltransferase
CAPG capping protein (actin filament), gelsolin-like
CASP3 caspase 3, apoptosis-related cysteine peptidase
CCNO cyclin O
CD302 CD302 molecule
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CHKB choline kinase beta
CHPF chondroitin polymerizing factor
CHUK conserved helix-loop-helix ubiquitous kinase
CIC capicua transcriptional repressor
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DNAL4 dynein, axonemal, light chain 4
DNMBP dynamin binding protein
DUSP5 dual specificity phosphatase 5
ETAA1 Ewing tumor-associated antigen 1
FANCC Fanconi anemia, complementation group C
FGGY FGGY carbohydrate kinase domain containing
FHOD1 formin homology 2 domain containing 1
GMIP GEM interacting protein
GNL3LP1 guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1
GPR87 G protein-coupled receptor 87
GUSBP3 glucuronidase, beta pseudogene 3
IRAK4 interleukin-1 receptor-associated kinase 4
KAT2A K(lysine) acetyltransferase 2A
KCNMB4 potassium channel subfamily M regulatory beta subunit 4
LCP1 lymphocyte cytosolic protein 1 (L-plastin)
LHFPL2 lipoma HMGIC fusion partner-like 2
LHX6 LIM homeobox 6
LMCD1 LIM and cysteine-rich domains 1
LRIG2 leucine-rich repeats and immunoglobulin-like domains 2
LYPLA2P1 lysophospholipase II pseudogene 1
MANBA mannosidase, beta A, lysosomal
MAST3 microtubule associated serine/threonine kinase 3
METTL2B methyltransferase like 2B
MOSPD3 motile sperm domain containing 3
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MTR 5-methyltetrahydrofolate-homocysteine methyltransferase
NABP2 nucleic acid binding protein 2
NDUFAF7 NADH dehydrogenase (ubiquinone) complex I, assembly factor 7
NPY5R neuropeptide Y receptor Y5
NRGN neurogranin (protein kinase C substrate, RC3)
PAQR4 progestin and adipoQ receptor family member IV
PARD6A par-6 family cell polarity regulator alpha
PARP16 poly (ADP-ribose) polymerase family, member 16
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PGGT1B protein geranylgeranyltransferase type I, beta subunit
PGP phosphoglycolate phosphatase
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma
PLD2 phospholipase D2
PLD3 phospholipase D family, member 3
PLIN3 perilipin 3
PTK6 protein tyrosine kinase 6
RAB11FIP1 RAB11 family interacting protein 1 (class I)
RAB5B RAB5B, member RAS oncogene family
SCHIP1 schwannomin interacting protein 1
SKA1 spindle and kinetochore associated complex subunit 1
SLC26A6 solute carrier family 26 (anion exchanger), member 6
SLC35A5 solute carrier family 35, member A5
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SOX13 SRY (sex determining region Y)-box 13
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1
STARD5 StAR-related lipid transfer (START) domain containing 5
STXBP2 syntaxin binding protein 2
SUSD4 sushi domain containing 4
SYNJ2BP synaptojanin 2 binding protein
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
TEAD3 TEA domain family member 3
TESK1 testis-specific kinase 1
TLN1 talin 1
TMA16 translation machinery associated 16 homolog (S. cerevisiae)
TOPORS topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase
TRAIP TRAF interacting protein
TRAPPC13 trafficking protein particle complex 13
TRMU tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
TUBGCP5 tubulin, gamma complex associated protein 5
UAP1L1 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1
VCPKMT valosin containing protein lysine (K) methyltransferase
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
ZNF134 zinc finger protein 134
ZNF219 zinc finger protein 219
ZNF282 zinc finger protein 282
ZNF573 zinc finger protein 573
ZNF668 zinc finger protein 668