negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway Gene Set

Dataset GO Biological Process Annotations
Category structural or functional annotations
Type biological process
Description Any process that decreases the rate, frequency, or extent of the series of molecular signals generated as a consequence of a transmembrane receptor serine/threonine kinase binding to its physiological ligand. (Gene Ontology, GO_0090101)
External Link http://amigo.geneontology.org/amigo/term/GO:0090101
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Genes

106 genes participating in the negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway biological process from the curated GO Biological Process Annotations dataset.

Symbol Name
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ACVR1 activin A receptor, type I
ADAM17 ADAM metallopeptidase domain 17
ADAMTSL2 ADAMTS-like 2
ASPN asporin
BAMBI BMP and activin membrane-bound inhibitor
BCL9L B-cell CLL/lymphoma 9-like
BMPER BMP binding endothelial regulator
CAV2 caveolin 2
CD109 CD109 molecule
CER1 cerberus 1, DAN family BMP antagonist
CHRD chordin
CHRDL1 chordin-like 1
CHRDL2 chordin-like 2
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11
CIDEA cell death-inducing DFFA-like effector a
DACT2 dishevelled-binding antagonist of beta-catenin 2
DAND5 DAN domain family member 5, BMP antagonist
DKK1 dickkopf WNT signaling pathway inhibitor 1
EID2 EP300 interacting inhibitor of differentiation 2
FAM89B family with sequence similarity 89, member B
FBN1 fibrillin 1
FBN2 fibrillin 2
FST follistatin
FSTL3 follistatin-like 3 (secreted glycoprotein)
FZD1 frizzled class receptor 1
GDF3 growth differentiation factor 3
GLG1 golgi glycoprotein 1
GREM1 gremlin 1, DAN family BMP antagonist
GREM2 gremlin 2, DAN family BMP antagonist
HIPK2 homeodomain interacting protein kinase 2
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
HTRA1 HtrA serine peptidase 1
HTRA3 HtrA serine peptidase 3
HTRA4 HtrA serine peptidase 4
LDLRAD4 low density lipoprotein receptor class A domain containing 4
LEMD3 LEM domain containing 3
LTBP1 latent transforming growth factor beta binding protein 1
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2
MTMR4 myotubularin related protein 4
NANOG Nanog homeobox
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
NKX2-1 NK2 homeobox 1
NOG noggin
NOTCH1 notch 1
ONECUT1 one cut homeobox 1
ONECUT2 one cut homeobox 2
PBLD phenazine biosynthesis-like protein domain containing
PDPK1 3-phosphoinositide dependent protein kinase 1
PEG10 paternally expressed 10
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PMEPA1 prostate transmembrane protein, androgen induced 1
PPM1A protein phosphatase, Mg2+/Mn2+ dependent, 1A
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme
PPP1CB protein phosphatase 1, catalytic subunit, beta isozyme
PPP1CC protein phosphatase 1, catalytic subunit, gamma isozyme
PPP1R15A protein phosphatase 1, regulatory subunit 15A
PRDM16 PR domain containing 16
RPS27A ribosomal protein S27a
SFRP1 secreted frizzled-related protein 1
SFRP2 secreted frizzled-related protein 2
SIRT1 sirtuin 1
SKI SKI proto-oncogene
SKIL SKI-like proto-oncogene
SKOR1 SKI family transcriptional corepressor 1
SKOR2 SKI family transcriptional corepressor 2
SMAD2 SMAD family member 2
SMAD3 SMAD family member 3
SMAD6 SMAD family member 6
SMAD7 SMAD family member 7
SMURF1 SMAD specific E3 ubiquitin protein ligase 1
SMURF2 SMAD specific E3 ubiquitin protein ligase 2
SNX25 sorting nexin 25
SNX6 sorting nexin 6
SOST sclerostin
SOSTDC1 sclerostin domain containing 1
SPG20 spastic paraplegia 20 (Troyer syndrome)
STRAP serine/threonine kinase receptor associated protein
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
SYNJ2BP synaptojanin 2 binding protein
TBX20 T-box 20
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TDGF1 teratocarcinoma-derived growth factor 1
TGFB1 transforming growth factor, beta 1
TGFB1I1 transforming growth factor beta 1 induced transcript 1
TGFB3 transforming growth factor, beta 3
TGFBR1 transforming growth factor, beta receptor 1
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TGFBR3 transforming growth factor, beta receptor III
TMPRSS6 transmembrane protease, serine 6
TOB1 transducer of ERBB2, 1
TP53 tumor protein p53
TRIM33 tripartite motif containing 33
TWSG1 twisted gastrulation BMP signaling modulator 1
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1
UBB ubiquitin B
UBC ubiquitin C
UCHL5 ubiquitin carboxyl-terminal hydrolase L5
USP15 ubiquitin specific peptidase 15
VASN vasorin
VWC2 von Willebrand factor C domain containing 2
VWC2L von Willebrand factor C domain containing protein 2-like
WNT1 wingless-type MMTV integration site family, member 1
WNT5A wingless-type MMTV integration site family, member 5A
XPO1 exportin 1
ZFYVE9 zinc finger, FYVE domain containing 9