negative regulation of protein modification process Gene Set

Dataset GO Biological Process Annotations
Category structural or functional annotations
Type biological process
Description Any process that stops, prevents, or reduces the frequency, rate or extent of the covalent alteration of one or more amino acid residues within a protein. (Gene Ontology, GO_0031400)
External Link http://amigo.geneontology.org/amigo/term/GO:0031400
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Genes

424 genes participating in the negative regulation of protein modification process biological process from the curated GO Biological Process Annotations dataset.

Symbol Name
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ACER2 alkaline ceramidase 2
ADAR adenosine deaminase, RNA-specific
ADARB1 adenosine deaminase, RNA-specific, B1
ADIPOQ adiponectin, C1Q and collagen domain containing
AIDA axin interactor, dorsalization associated
AKT1 v-akt murine thymoma viral oncogene homolog 1
AKT1S1 AKT1 substrate 1 (proline-rich)
ANAPC1 anaphase promoting complex subunit 1
ANAPC10 anaphase promoting complex subunit 10
ANAPC11 anaphase promoting complex subunit 11
ANAPC2 anaphase promoting complex subunit 2
ANAPC4 anaphase promoting complex subunit 4
ANAPC5 anaphase promoting complex subunit 5
ANAPC7 anaphase promoting complex subunit 7
ANGPT1 angiopoietin 1
APC adenomatous polyposis coli
APOE apolipoprotein E
ARRB1 arrestin, beta 1
ARRB2 arrestin, beta 2
ATG14 autophagy related 14
ATG5 autophagy related 5
ATG7 autophagy related 7
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4
BAG5 BCL2-associated athanogene 5
BAK1 BCL2-antagonist/killer 1
BAX BCL2-associated X protein
BCOR BCL6 corepressor
BDKRB1 bradykinin receptor B1
BDKRB2 bradykinin receptor B2
BMP4 bone morphogenetic protein 4
BMP7 bone morphogenetic protein 7
BRCA1 breast cancer 1, early onset
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B
BUB3 BUB3 mitotic checkpoint protein
CACTIN cactin, spliceosome C complex subunit
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1
CAMK2N2 calcium/calmodulin-dependent protein kinase II inhibitor 2
CAPN3 calpain 3, (p94)
CASP3 caspase 3, apoptosis-related cysteine peptidase
CAV1 caveolin 1, caveolae protein, 22kDa
CAV3 caveolin 3
CBLC Cbl proto-oncogene C, E3 ubiquitin protein ligase
CCDC23 coiled-coil domain containing 23
CCNB1 cyclin B1
CD109 CD109 molecule
CD300A CD300a molecule
CDC16 cell division cycle 16
CDC20 cell division cycle 20
CDC23 cell division cycle 23
CDC26 cell division cycle 26
CDC27 cell division cycle 27
CDK5 cyclin-dependent kinase 5
CDK5RAP1 CDK5 regulatory subunit associated protein 1
CDK5RAP3 CDK5 regulatory subunit associated protein 3
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CDKN2A cyclin-dependent kinase inhibitor 2A
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CHORDC1 cysteine and histidine-rich domain (CHORD) containing 1
CHP1 calcineurin-like EF-hand protein 1
CIB1 calcium and integrin binding 1 (calmyrin)
CISH cytokine inducible SH2-containing protein
CNKSR3 CNKSR family member 3
CRIPAK cysteine-rich PAK1 inhibitor
CRTAP cartilage associated protein
CRY1 cryptochrome circadian clock 1
CTBP1 C-terminal binding protein 1
CTDSP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
CTDSP2 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2
CTDSPL CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
DAB2IP DAB2 interacting protein
DBNDD2 dysbindin (dystrobrevin binding protein 1) domain containing 2
DDIT4 DNA-damage-inducible transcript 4
DEPTOR DEP domain containing MTOR-interacting protein
DKK1 dickkopf WNT signaling pathway inhibitor 1
DMD dystrophin
DMTN dematin actin binding protein
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1
DNAJC10 DnaJ (Hsp40) homolog, subfamily C, member 10
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3
DNMT1 DNA (cytosine-5-)-methyltransferase 1
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta
DUS2 dihydrouridine synthase 2
DUSP1 dual specificity phosphatase 1
DUSP10 dual specificity phosphatase 10
DUSP14 dual specificity phosphatase 14
DUSP16 dual specificity phosphatase 16
DUSP18 dual specificity phosphatase 18
DUSP19 dual specificity phosphatase 19
DUSP2 dual specificity phosphatase 2
DUSP21 dual specificity phosphatase 21
DUSP22 dual specificity phosphatase 22
DUSP26 dual specificity phosphatase 26 (putative)
DUSP3 dual specificity phosphatase 3
DUSP4 dual specificity phosphatase 4
DUSP5 dual specificity phosphatase 5
DUSP6 dual specificity phosphatase 6
DUSP7 dual specificity phosphatase 7
DUSP8 dual specificity phosphatase 8
DUSP9 dual specificity phosphatase 9
DVL1 dishevelled segment polarity protein 1
ENG endoglin
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
EPHA1 EPH receptor A1
ERRFI1 ERBB receptor feedback inhibitor 1
FABP4 fatty acid binding protein 4, adipocyte
FAM129A family with sequence similarity 129, member A
FBXO5 F-box protein 5
FBXO7 F-box protein 7
FGFR1OP FGFR1 oncogene partner
FKBP1A FK506 binding protein 1A, 12kDa
FOXP3 forkhead box P3
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
G6PD glucose-6-phosphate dehydrogenase
GADD45A growth arrest and DNA-damage-inducible, alpha
GADD45B growth arrest and DNA-damage-inducible, beta
GADD45G growth arrest and DNA-damage-inducible, gamma
GBA glucosidase, beta, acid
GCLC glutamate-cysteine ligase, catalytic subunit
GFRA2 GDNF family receptor alpha 2
GLMN glomulin, FKBP associated protein
GMFB glia maturation factor, beta
GMFG glia maturation factor, gamma
GNAQ guanine nucleotide binding protein (G protein), q polypeptide
GNB2L1 guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1
GPD1L glycerol-3-phosphate dehydrogenase 1-like
GPS1 G protein pathway suppressor 1
GPS2 G protein pathway suppressor 2
GREM1 gremlin 1, DAN family BMP antagonist
GSK3B glycogen synthase kinase 3 beta
GSTP1 glutathione S-transferase pi 1
GTPBP4 GTP binding protein 4
H2AFY H2A histone family, member Y
HEXIM1 hexamethylene bis-acetamide inducible 1
HEXIM2 hexamethylene bis-acetamide inducible 2
HFE hemochromatosis
HHATL hedgehog acyltransferase-like
HHEX hematopoietically expressed homeobox
HIPK3 homeodomain interacting protein kinase 3
HMG20B high mobility group 20B
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
HSPB1 heat shock 27kDa protein 1
HYAL2 hyaluronoglucosaminidase 2
IBTK inhibitor of Bruton agammaglobulinemia tyrosine kinase
IGBP1 immunoglobulin (CD79A) binding protein 1
IGF1R insulin-like growth factor 1 receptor
IGFBP3 insulin-like growth factor binding protein 3
IL1B interleukin 1, beta
IL2 interleukin 2
IL6 interleukin 6
ILK integrin-linked kinase
IMPACT impact RWD domain protein
INCA1 inhibitor of CDK, cyclin A1 interacting protein 1
INPP5J inositol polyphosphate-5-phosphatase J
INPP5K inositol polyphosphate-5-phosphatase K
INSM1 insulinoma-associated 1
IRAK3 interleukin-1 receptor-associated kinase 3
ISG15 ISG15 ubiquitin-like modifier
ITGB1BP1 integrin beta 1 binding protein 1
JARID2 jumonji, AT rich interactive domain 2
JUN jun proto-oncogene
KAT2B K(lysine) acetyltransferase 2B
KDM1A lysine (K)-specific demethylase 1A
KDM3A lysine (K)-specific demethylase 3A
KDM5A lysine (K)-specific demethylase 5A
KIRREL kin of IRRE like (Drosophila)
KIRREL2 kin of IRRE like 2 (Drosophila)
KLF15 Kruppel-like factor 15
LATS1 large tumor suppressor kinase 1
LATS2 large tumor suppressor kinase 2
LAX1 lymphocyte transmembrane adaptor 1
LDLRAD4 low density lipoprotein receptor class A domain containing 4
LIMK1 LIM domain kinase 1
LRP5 low density lipoprotein receptor-related protein 5
LRP6 low density lipoprotein receptor-related protein 6
LRRK1 leucine-rich repeat kinase 1
LRRK2 leucine-rich repeat kinase 2
LYN LYN proto-oncogene, Src family tyrosine kinase
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast)
MAD2L2 MAD2 mitotic arrest deficient-like 2 (yeast)
MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1
MAS1 MAS1 proto-oncogene, G protein-coupled receptor
MBIP MAP3K12 binding inhibitory protein 1
MECP2 methyl CpG binding protein 2
MEN1 multiple endocrine neoplasia I
MGEA5 meningioma expressed antigen 5 (hyaluronidase)
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1
MLLT1 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1
MLXIPL MLX interacting protein-like
MTF2 metal response element binding transcription factor 2
MVP major vault protein
MYADM myeloid-associated differentiation marker
MYOCD myocardin
N4BP1 NEDD4 binding protein 1
NCK1 NCK adaptor protein 1
NCK2 NCK adaptor protein 2
NF1 neurofibromin 1
NF2 neurofibromin 2 (merlin)
NLRP12 NLR family, pyrin domain containing 12
NOC2L nucleolar complex associated 2 homolog (S. cerevisiae)
NOG noggin
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin)
NR2F2 nuclear receptor subfamily 2, group F, member 2
NTF3 neurotrophin 3
NTRK3 neurotrophic tyrosine kinase, receptor, type 3
NUP62 nucleoporin 62kDa
NXN nucleoredoxin
OGT O-linked N-acetylglucosamine (GlcNAc) transferase
OTUB1 OTU deubiquitinase, ubiquitin aldehyde binding 1
P3H1 prolyl 3-hydroxylase 1
PAK2 p21 protein (Cdc42/Rac)-activated kinase 2
PAQR3 progestin and adipoQ receptor family member III
PARD3 par-3 family cell polarity regulator
PARK2 parkin RBR E3 ubiquitin protein ligase
PARK7 parkinson protein 7
PARP10 poly (ADP-ribose) polymerase family, member 10
PAX5 paired box 5
PAX6 paired box 6
PBK PDZ binding kinase
PBLD phenazine biosynthesis-like protein domain containing
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
PDCL3 phosducin-like 3
PDE4D phosphodiesterase 4D, cAMP-specific
PDPK1 3-phosphoinositide dependent protein kinase 1
PELI3 pellino E3 ubiquitin protein ligase family member 3
PER2 period circadian clock 2
PHF1 PHD finger protein 1
PID1 phosphotyrosine interaction domain containing 1
PKIA protein kinase (cAMP-dependent, catalytic) inhibitor alpha
PKIB protein kinase (cAMP-dependent, catalytic) inhibitor beta
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma
PLK1 polo-like kinase 1
PMEPA1 prostate transmembrane protein, androgen induced 1
PML promyelocytic leukemia
PPAP2B phosphatidic acid phosphatase type 2B
PPEF2 protein phosphatase, EF-hand calcium binding domain 2
PPM1E protein phosphatase, Mg2+/Mn2+ dependent, 1E
PPM1F protein phosphatase, Mg2+/Mn2+ dependent, 1F
PPP1R15A protein phosphatase 1, regulatory subunit 15A
PPP1R16B protein phosphatase 1, regulatory subunit 16B
PPP1R1A protein phosphatase 1, regulatory (inhibitor) subunit 1A
PPP1R1B protein phosphatase 1, regulatory (inhibitor) subunit 1B
PPP1R1C protein phosphatase 1, regulatory (inhibitor) subunit 1C
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha
PPP2R4 protein phosphatase 2A activator, regulatory subunit 4
PRKAG2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha
PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta
PRKAR2A protein kinase, cAMP-dependent, regulatory, type II, alpha
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PRKCA protein kinase C, alpha
PRKCD protein kinase C, delta
PRKCG protein kinase C, gamma
PRKCZ protein kinase C, zeta
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PRKRIP1 PRKR interacting protein 1 (IL11 inducible)
PRMT3 protein arginine methyltransferase 3
PRNP prion protein
PRR5L proline rich 5 like
PSEN1 presenilin 1
PSEN2 presenilin 2
PSMA1 proteasome (prosome, macropain) subunit, alpha type, 1
PSMA2 proteasome (prosome, macropain) subunit, alpha type, 2
PSMA3 proteasome (prosome, macropain) subunit, alpha type, 3
PSMA4 proteasome (prosome, macropain) subunit, alpha type, 4
PSMA5 proteasome (prosome, macropain) subunit, alpha type, 5
PSMA6 proteasome (prosome, macropain) subunit, alpha type, 6
PSMA7 proteasome (prosome, macropain) subunit, alpha type, 7
PSMB1 proteasome (prosome, macropain) subunit, beta type, 1
PSMB10 proteasome (prosome, macropain) subunit, beta type, 10
PSMB2 proteasome (prosome, macropain) subunit, beta type, 2
PSMB3 proteasome (prosome, macropain) subunit, beta type, 3
PSMB4 proteasome (prosome, macropain) subunit, beta type, 4
PSMB5 proteasome (prosome, macropain) subunit, beta type, 5
PSMB6 proteasome (prosome, macropain) subunit, beta type, 6
PSMB7 proteasome (prosome, macropain) subunit, beta type, 7
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9
PSMC1 proteasome (prosome, macropain) 26S subunit, ATPase, 1
PSMC2 proteasome (prosome, macropain) 26S subunit, ATPase, 2
PSMC3 proteasome (prosome, macropain) 26S subunit, ATPase, 3
PSMC4 proteasome (prosome, macropain) 26S subunit, ATPase, 4
PSMC5 proteasome (prosome, macropain) 26S subunit, ATPase, 5
PSMC6 proteasome (prosome, macropain) 26S subunit, ATPase, 6
PSMD1 proteasome (prosome, macropain) 26S subunit, non-ATPase, 1
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
PSMD11 proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
PSMD12 proteasome (prosome, macropain) 26S subunit, non-ATPase, 12
PSMD13 proteasome (prosome, macropain) 26S subunit, non-ATPase, 13
PSMD14 proteasome (prosome, macropain) 26S subunit, non-ATPase, 14
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
PSMD3 proteasome (prosome, macropain) 26S subunit, non-ATPase, 3
PSMD4 proteasome (prosome, macropain) 26S subunit, non-ATPase, 4
PSMD5 proteasome (prosome, macropain) 26S subunit, non-ATPase, 5
PSMD6 proteasome (prosome, macropain) 26S subunit, non-ATPase, 6
PSMD7 proteasome (prosome, macropain) 26S subunit, non-ATPase, 7
PSMD8 proteasome (prosome, macropain) 26S subunit, non-ATPase, 8
PSMD9 proteasome (prosome, macropain) 26S subunit, non-ATPase, 9
PSME1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
PSME2 proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
PSME3 proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)
PSMF1 proteasome (prosome, macropain) inhibitor subunit 1 (PI31)
PTEN phosphatase and tensin homolog
PTK6 protein tyrosine kinase 6
PTPN1 protein tyrosine phosphatase, non-receptor type 1
PTPN2 protein tyrosine phosphatase, non-receptor type 2
PTPN6 protein tyrosine phosphatase, non-receptor type 6
PTPRC protein tyrosine phosphatase, receptor type, C
PTPRJ protein tyrosine phosphatase, receptor type, J
PYCARD PYD and CARD domain containing
PYDC1 PYD (pyrin domain) containing 1
RABGEF1 RAB guanine nucleotide exchange factor (GEF) 1
RASD2 RASD family, member 2
RB1 retinoblastoma 1
RGS14 regulator of G-protein signaling 14
RGS2 regulator of G-protein signaling 2
RGS3 regulator of G-protein signaling 3
RGS4 regulator of G-protein signaling 4
RPS27A ribosomal protein S27a
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SENP2 SUMO1/sentrin/SMT3 specific peptidase 2
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3
SET SET nuclear proto-oncogene
SFN stratifin
SFRP1 secreted frizzled-related protein 1
SFRP2 secreted frizzled-related protein 2
SFRP5 secreted frizzled-related protein 5
SH3BP5 SH3-domain binding protein 5 (BTK-associated)
SIN3A SIN3 transcription regulator family member A
SIRT1 sirtuin 1
SIRT2 sirtuin 2
SKI SKI proto-oncogene
SLIT2 slit homolog 2 (Drosophila)
SMAD3 SMAD family member 3
SMAD6 SMAD family member 6
SMAD7 SMAD family member 7
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal
SMYD3 SET and MYND domain containing 3
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SNTA1 syntrophin, alpha 1
SNX25 sorting nexin 25
SNX6 sorting nexin 6
SOCS1 suppressor of cytokine signaling 1
SOCS2 suppressor of cytokine signaling 2
SOCS3 suppressor of cytokine signaling 3
SOCS4 suppressor of cytokine signaling 4
SOCS5 suppressor of cytokine signaling 5
SOCS6 suppressor of cytokine signaling 6
SOCS7 suppressor of cytokine signaling 7
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
SOX4 SRY (sex determining region Y)-box 4
SPI1 Spi-1 proto-oncogene
SPINK1 serine peptidase inhibitor, Kazal type 1
SPOPL speckle-type POZ protein-like
SPRED1 sprouty-related, EVH1 domain containing 1
SPRED2 sprouty-related, EVH1 domain containing 2
SPRED3 sprouty-related, EVH1 domain containing 3
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
SPRY2 sprouty homolog 2 (Drosophila)
SPRY4 sprouty homolog 4 (Drosophila)
SRCIN1 SRC kinase signaling inhibitor 1
STK38 serine/threonine kinase 38
STRAP serine/threonine kinase receptor associated protein
SUFU suppressor of fused homolog (Drosophila)
SUPT6H suppressor of Ty 6 homolog (S. cerevisiae)
TAF7 TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa
TAOK3 TAO kinase 3
TARBP2 TAR (HIV-1) RNA binding protein 2
TARDBP TAR DNA binding protein
TESC tescalcin
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TGFB1 transforming growth factor, beta 1
THY1 Thy-1 cell surface antigen
TINF2 TERF1 (TRF1)-interacting nuclear factor 2
TMEM59 transmembrane protein 59
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TP73 tumor protein p73
TRAF3IP1 TNF receptor-associated factor 3 interacting protein 1
TRIB1 tribbles pseudokinase 1
TRIB2 tribbles pseudokinase 2
TRIB3 tribbles pseudokinase 3
TRIM21 tripartite motif containing 21
TRIM27 tripartite motif containing 27
TRIM39 tripartite motif containing 39
TRIP12 thyroid hormone receptor interactor 12
TSC2 tuberous sclerosis 2
TWIST1 twist family bHLH transcription factor 1
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1
UBASH3B ubiquitin associated and SH3 domain containing B
UBB ubiquitin B
UBC ubiquitin C
UBE2B ubiquitin-conjugating enzyme E2B
UBE2C ubiquitin-conjugating enzyme E2C
UBE2D1 ubiquitin-conjugating enzyme E2D 1
UBE2E1 ubiquitin-conjugating enzyme E2E 1
UBR5 ubiquitin protein ligase E3 component n-recognin 5
UBXN1 UBX domain protein 1
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
UCN urocortin
UFL1 UFM1-specific ligase 1
USP17L2 ubiquitin specific peptidase 17-like family member 2
USP4 ubiquitin specific peptidase 4 (proto-oncogene)
USP44 ubiquitin specific peptidase 44
VPS28 vacuolar protein sorting 28 homolog (S. cerevisiae)
WEE2 WEE1 homolog 2 (S. pombe)
WNK1 WNK lysine deficient protein kinase 1
WNT1 wingless-type MMTV integration site family, member 1
WWTR1 WW domain containing transcription regulator 1
XDH xanthine dehydrogenase
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma
ZBED3 zinc finger, BED-type containing 3
ZFYVE28 zinc finger, FYVE domain containing 28
ZGPAT zinc finger, CCCH-type with G patch domain
ZNF675 zinc finger protein 675