negative regulation of protein kinase activity Gene Set

Dataset GO Biological Process Annotations
Category structural or functional annotations
Type biological process
Description Any process that stops, prevents, or reduces the frequency, rate or extent of protein kinase activity. (Gene Ontology, GO_0006469)
External Link http://amigo.geneontology.org/amigo/term/GO:0006469
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Genes

196 genes participating in the negative regulation of protein kinase activity biological process from the curated GO Biological Process Annotations dataset.

Symbol Name
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ADAR adenosine deaminase, RNA-specific
ADARB1 adenosine deaminase, RNA-specific, B1
ADIPOQ adiponectin, C1Q and collagen domain containing
AIDA axin interactor, dorsalization associated
AKT1 v-akt murine thymoma viral oncogene homolog 1
AKT1S1 AKT1 substrate 1 (proline-rich)
APC adenomatous polyposis coli
APOE apolipoprotein E
BMP4 bone morphogenetic protein 4
BMP7 bone morphogenetic protein 7
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1
CAMK2N2 calcium/calmodulin-dependent protein kinase II inhibitor 2
CASP3 caspase 3, apoptosis-related cysteine peptidase
CAV1 caveolin 1, caveolae protein, 22kDa
CAV3 caveolin 3
CBLC Cbl proto-oncogene C, E3 ubiquitin protein ligase
CD300A CD300a molecule
CDK5RAP1 CDK5 regulatory subunit associated protein 1
CDK5RAP3 CDK5 regulatory subunit associated protein 3
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CDKN2A cyclin-dependent kinase inhibitor 2A
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CHORDC1 cysteine and histidine-rich domain (CHORD) containing 1
CHP1 calcineurin-like EF-hand protein 1
CIB1 calcium and integrin binding 1 (calmyrin)
CISH cytokine inducible SH2-containing protein
CRIPAK cysteine-rich PAK1 inhibitor
DAB2IP DAB2 interacting protein
DBNDD2 dysbindin (dystrobrevin binding protein 1) domain containing 2
DEPTOR DEP domain containing MTOR-interacting protein
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3
DUS2 dihydrouridine synthase 2
DUSP1 dual specificity phosphatase 1
DUSP10 dual specificity phosphatase 10
DUSP14 dual specificity phosphatase 14
DUSP16 dual specificity phosphatase 16
DUSP18 dual specificity phosphatase 18
DUSP19 dual specificity phosphatase 19
DUSP2 dual specificity phosphatase 2
DUSP21 dual specificity phosphatase 21
DUSP22 dual specificity phosphatase 22
DUSP26 dual specificity phosphatase 26 (putative)
DUSP3 dual specificity phosphatase 3
DUSP4 dual specificity phosphatase 4
DUSP5 dual specificity phosphatase 5
DUSP6 dual specificity phosphatase 6
DUSP7 dual specificity phosphatase 7
DUSP8 dual specificity phosphatase 8
DUSP9 dual specificity phosphatase 9
DVL1 dishevelled segment polarity protein 1
EPHA1 EPH receptor A1
ERRFI1 ERBB receptor feedback inhibitor 1
FABP4 fatty acid binding protein 4, adipocyte
FBXO7 F-box protein 7
FGFR1OP FGFR1 oncogene partner
GADD45A growth arrest and DNA-damage-inducible, alpha
GADD45B growth arrest and DNA-damage-inducible, beta
GADD45G growth arrest and DNA-damage-inducible, gamma
GBA glucosidase, beta, acid
GMFB glia maturation factor, beta
GMFG glia maturation factor, gamma
GNAQ guanine nucleotide binding protein (G protein), q polypeptide
GNB2L1 guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1
GPS1 G protein pathway suppressor 1
GPS2 G protein pathway suppressor 2
GSK3B glycogen synthase kinase 3 beta
GSTP1 glutathione S-transferase pi 1
H2AFY H2A histone family, member Y
HEXIM1 hexamethylene bis-acetamide inducible 1
HEXIM2 hexamethylene bis-acetamide inducible 2
HHEX hematopoietically expressed homeobox
HIPK3 homeodomain interacting protein kinase 3
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
HSPB1 heat shock 27kDa protein 1
HYAL2 hyaluronoglucosaminidase 2
IBTK inhibitor of Bruton agammaglobulinemia tyrosine kinase
IGF1R insulin-like growth factor 1 receptor
IL1B interleukin 1, beta
IL6 interleukin 6
ILK integrin-linked kinase
INCA1 inhibitor of CDK, cyclin A1 interacting protein 1
INPP5K inositol polyphosphate-5-phosphatase K
IRAK3 interleukin-1 receptor-associated kinase 3
ITGB1BP1 integrin beta 1 binding protein 1
KAT2B K(lysine) acetyltransferase 2B
LATS1 large tumor suppressor kinase 1
LATS2 large tumor suppressor kinase 2
LAX1 lymphocyte transmembrane adaptor 1
LRP5 low density lipoprotein receptor-related protein 5
LRP6 low density lipoprotein receptor-related protein 6
LYN LYN proto-oncogene, Src family tyrosine kinase
MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1
MBIP MAP3K12 binding inhibitory protein 1
MEN1 multiple endocrine neoplasia I
MLLT1 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1
MVP major vault protein
MYOCD myocardin
NCK1 NCK adaptor protein 1
NF1 neurofibromin 1
NF2 neurofibromin 2 (merlin)
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin)
NR2F2 nuclear receptor subfamily 2, group F, member 2
NUP62 nucleoporin 62kDa
PAK2 p21 protein (Cdc42/Rac)-activated kinase 2
PAQR3 progestin and adipoQ receptor family member III
PARK7 parkinson protein 7
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
PDPK1 3-phosphoinositide dependent protein kinase 1
PKIA protein kinase (cAMP-dependent, catalytic) inhibitor alpha
PKIB protein kinase (cAMP-dependent, catalytic) inhibitor beta
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma
PLK1 polo-like kinase 1
PPM1E protein phosphatase, Mg2+/Mn2+ dependent, 1E
PPM1F protein phosphatase, Mg2+/Mn2+ dependent, 1F
PPP1R1A protein phosphatase 1, regulatory (inhibitor) subunit 1A
PPP1R1B protein phosphatase 1, regulatory (inhibitor) subunit 1B
PPP1R1C protein phosphatase 1, regulatory (inhibitor) subunit 1C
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha
PRKAG2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha
PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta
PRKAR2A protein kinase, cAMP-dependent, regulatory, type II, alpha
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PRKCA protein kinase C, alpha
PRKCD protein kinase C, delta
PRKRIP1 PRKR interacting protein 1 (IL11 inducible)
PSEN1 presenilin 1
PTEN phosphatase and tensin homolog
PTK6 protein tyrosine kinase 6
PTPN1 protein tyrosine phosphatase, non-receptor type 1
PTPN6 protein tyrosine phosphatase, non-receptor type 6
PTPRC protein tyrosine phosphatase, receptor type, C
PTPRJ protein tyrosine phosphatase, receptor type, J
PYCARD PYD and CARD domain containing
PYDC1 PYD (pyrin domain) containing 1
RB1 retinoblastoma 1
RGS14 regulator of G-protein signaling 14
RGS2 regulator of G-protein signaling 2
RGS3 regulator of G-protein signaling 3
RGS4 regulator of G-protein signaling 4
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3
SFN stratifin
SFRP1 secreted frizzled-related protein 1
SFRP2 secreted frizzled-related protein 2
SFRP5 secreted frizzled-related protein 5
SH3BP5 SH3-domain binding protein 5 (BTK-associated)
SIRT1 sirtuin 1
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal
SMYD3 SET and MYND domain containing 3
SNX6 sorting nexin 6
SOCS1 suppressor of cytokine signaling 1
SOCS2 suppressor of cytokine signaling 2
SOCS3 suppressor of cytokine signaling 3
SOCS4 suppressor of cytokine signaling 4
SOCS5 suppressor of cytokine signaling 5
SOCS6 suppressor of cytokine signaling 6
SOCS7 suppressor of cytokine signaling 7
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
SPRED1 sprouty-related, EVH1 domain containing 1
SPRED2 sprouty-related, EVH1 domain containing 2
SPRED3 sprouty-related, EVH1 domain containing 3
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
SPRY2 sprouty homolog 2 (Drosophila)
SPRY4 sprouty homolog 4 (Drosophila)
SRCIN1 SRC kinase signaling inhibitor 1
STK38 serine/threonine kinase 38
TAF7 TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa
TAOK3 TAO kinase 3
TARBP2 TAR (HIV-1) RNA binding protein 2
TESC tescalcin
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
THY1 Thy-1 cell surface antigen
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TP73 tumor protein p73
TRIB1 tribbles pseudokinase 1
TRIB2 tribbles pseudokinase 2
TRIB3 tribbles pseudokinase 3
TRIM27 tripartite motif containing 27
TSC2 tuberous sclerosis 2
UBASH3B ubiquitin associated and SH3 domain containing B
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
WEE2 WEE1 homolog 2 (S. pombe)
WNK1 WNK lysine deficient protein kinase 1
WWTR1 WW domain containing transcription regulator 1
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma
ZFYVE28 zinc finger, FYVE domain containing 28
ZGPAT zinc finger, CCCH-type with G patch domain
ZNF675 zinc finger protein 675