negative regulation of peptidase activity Gene Set

Dataset GO Biological Process Annotations
Category structural or functional annotations
Type biological process
Description Any process that stops or reduces the rate of peptidase activity, the hydrolysis of peptide bonds within proteins. (Gene Ontology, GO_0010466)
External Link http://amigo.geneontology.org/amigo/term/GO:0010466
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Genes

219 genes participating in the negative regulation of peptidase activity biological process from the curated GO Biological Process Annotations dataset.

Symbol Name
A2M alpha-2-macroglobulin
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AHSG alpha-2-HS-glycoprotein
AKT1 v-akt murine thymoma viral oncogene homolog 1
AMBP alpha-1-microglobulin/bikunin precursor
ANOS1 anosmin 1
APLP2 amyloid beta (A4) precursor-like protein 2
APP amyloid beta (A4) precursor protein
AQP1 aquaporin 1 (Colton blood group)
ARRB1 arrestin, beta 1
ARRB2 arrestin, beta 2
AVP arginine vasopressin
BCL2L12 BCL2-like 12 (proline rich)
BIRC2 baculoviral IAP repeat containing 2
BIRC3 baculoviral IAP repeat containing 3
BIRC5 baculoviral IAP repeat containing 5
BIRC6 baculoviral IAP repeat containing 6
BIRC7 baculoviral IAP repeat containing 7
BIRC8 baculoviral IAP repeat containing 8
BST2 bone marrow stromal cell antigen 2
C3 complement component 3
C5 complement component 5
CARD16 caspase recruitment domain family, member 16
CARD17 caspase recruitment domain family, member 17
CARD18 caspase recruitment domain family, member 18
CAST calpastatin
CD109 CD109 molecule
CD27 CD27 molecule
CD44 CD44 molecule (Indian blood group)
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
COL28A1 collagen, type XXVIII, alpha 1
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen)
COL6A3 collagen, type VI, alpha 3
COL7A1 collagen, type VII, alpha 1
CPAMD8 C3 and PZP-like, alpha-2-macroglobulin domain containing 8
CR1 complement component (3b/4b) receptor 1 (Knops blood group)
CRB2 crumbs family member 2
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like)
CRYAB crystallin, alpha B
CSNK2A1 casein kinase 2, alpha 1 polypeptide
CST1 cystatin SN
CST11 cystatin 11
CST2 cystatin SA
CST3 cystatin C
CST4 cystatin S
CST5 cystatin D
CST6 cystatin E/M
CST7 cystatin F (leukocystatin)
CST8 cystatin 8 (cystatin-related epididymal specific)
CST9 cystatin 9 (testatin)
CST9L cystatin 9-like
CSTA cystatin A (stefin A)
CSTB cystatin B (stefin B)
CSTL1 cystatin-like 1
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
DHCR24 24-dehydrocholesterol reductase
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6
DPEP1 dipeptidase 1 (renal)
ECM1 extracellular matrix protein 1
FABP1 fatty acid binding protein 1, liver
FETUB fetuin B
FNIP1 folliculin interacting protein 1
FURIN furin (paired basic amino acid cleaving enzyme)
GAS6 growth arrest-specific 6
GPC3 glypican 3
GPI glucose-6-phosphate isomerase
GPX1 glutathione peroxidase 1
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HMSD histocompatibility (minor) serpin domain containing
HRG histidine-rich glycoprotein
IFI16 interferon, gamma-inducible protein 16
IFI6 interferon, alpha-inducible protein 6
IGBP1 immunoglobulin (CD79A) binding protein 1
IL24 interleukin 24
IL6 interleukin 6
INTS1 integrator complex subunit 1
ITIH1 inter-alpha-trypsin inhibitor heavy chain 1
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2
ITIH3 inter-alpha-trypsin inhibitor heavy chain 3
ITIH4 inter-alpha-trypsin inhibitor heavy chain family, member 4
ITIH5 inter-alpha-trypsin inhibitor heavy chain family, member 5
ITIH6 inter-alpha-trypsin inhibitor heavy chain family, member 6
KLF4 Kruppel-like factor 4 (gut)
KNG1 kininogen 1
LAMTOR5 late endosomal/lysosomal adaptor, MAPK and MTOR activator 5
LCN1 lipocalin 1
LEF1 lymphoid enhancer-binding factor 1
LXN latexin
MAP2K5 mitogen-activated protein kinase kinase 5
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1
MKL1 megakaryoblastic leukemia (translocation) 1
MMP9 matrix metallopeptidase 9
MT3 metallothionein 3
NAIP NLR family, apoptosis inhibitory protein
NGF nerve growth factor (beta polypeptide)
NLE1 notchless homolog 1 (Drosophila)
NLRC4 NLR family, CARD domain containing 4
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain)
PAK2 p21 protein (Cdc42/Rac)-activated kinase 2
PAPLN papilin, proteoglycan-like sulfated glycoprotein
PARK7 parkinson protein 7
PAX2 paired box 2
PCID2 PCI domain containing 2
PCSK1N proprotein convertase subtilisin/kexin type 1 inhibitor
PEBP1 phosphatidylethanolamine binding protein 1
PI15 peptidase inhibitor 15
PI16 peptidase inhibitor 16
PI3 peptidase inhibitor 3, skin-derived
PICALM phosphatidylinositol binding clathrin assembly protein
PLAUR plasminogen activator, urokinase receptor
POR P450 (cytochrome) oxidoreductase
PRDX3 peroxiredoxin 3
PRDX5 peroxiredoxin 5
PROL1 proline rich, lacrimal 1
PROS1 protein S (alpha)
PSMF1 proteasome (prosome, macropain) inhibitor subunit 1 (PI31)
PTTG1 pituitary tumor-transforming 1
R3HDML R3H domain containing-like
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RAG1 recombination activating gene 1
RECK reversion-inducing-cysteine-rich protein with kazal motifs
RENBP renin binding protein
RFFL ring finger and FYVE-like domain containing E3 ubiquitin protein ligase
RNF34 ring finger protein 34, E3 ubiquitin protein ligase
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1
RPS6KA3 ribosomal protein S6 kinase, 90kDa, polypeptide 3
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINA10 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10
SERPINA11 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 11
SERPINA12 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SERPINA4 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SERPINA6 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6
SERPINA7 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7
SERPINA9 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 9
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1
SERPINB10 serpin peptidase inhibitor, clade B (ovalbumin), member 10
SERPINB11 serpin peptidase inhibitor, clade B (ovalbumin), member 11 (gene/pseudogene)
SERPINB12 serpin peptidase inhibitor, clade B (ovalbumin), member 12
SERPINB13 serpin peptidase inhibitor, clade B (ovalbumin), member 13
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3
SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SERPINB6 serpin peptidase inhibitor, clade B (ovalbumin), member 6
SERPINB7 serpin peptidase inhibitor, clade B (ovalbumin), member 7
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1
SERPIND1 serpin peptidase inhibitor, clade D (heparin cofactor), member 1
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SERPINE3 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 3
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SERPINF2 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SERPINI2 serpin peptidase inhibitor, clade I (pancpin), member 2
SFN stratifin
SFRP2 secreted frizzled-related protein 2
SH3RF1 SH3 domain containing ring finger 1
SIAH2 siah E3 ubiquitin protein ligase 2
SLPI secretory leukocyte peptidase inhibitor
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
SPINK1 serine peptidase inhibitor, Kazal type 1
SPINK13 serine peptidase inhibitor, Kazal type 13 (putative)
SPINK14 serine peptidase inhibitor, Kazal type 14 (putative)
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor)
SPINK4 serine peptidase inhibitor, Kazal type 4
SPINK5 serine peptidase inhibitor, Kazal type 5
SPINK6 serine peptidase inhibitor, Kazal type 6
SPINK7 serine peptidase inhibitor, Kazal type 7 (putative)
SPINK8 serine peptidase inhibitor, Kazal type 8 (putative)
SPINK9 serine peptidase inhibitor, Kazal type 9
SPINT1 serine peptidase inhibitor, Kunitz type 1
SPINT2 serine peptidase inhibitor, Kunitz type, 2
SPINT3 serine peptidase inhibitor, Kunitz type, 3
SPINT4 serine peptidase inhibitor, Kunitz type 4
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
SPOCK3 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
SPP2 secreted phosphoprotein 2, 24kDa
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SSPO SCO-spondin
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TFPI2 tissue factor pathway inhibitor 2
THBS1 thrombospondin 1
TIMP1 TIMP metallopeptidase inhibitor 1
TIMP2 TIMP metallopeptidase inhibitor 2
TIMP3 TIMP metallopeptidase inhibitor 3
TIMP4 TIMP metallopeptidase inhibitor 4
TNFAIP8 tumor necrosis factor, alpha-induced protein 8
TNFSF14 tumor necrosis factor (ligand) superfamily, member 14
TRIAP1 TP53 regulated inhibitor of apoptosis 1
UCHL5 ubiquitin carboxyl-terminal hydrolase L5
UMODL1 uromodulin-like 1
USP14 ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)
USP47 ubiquitin specific peptidase 47
VEGFA vascular endothelial growth factor A
VIL1 villin 1
VTN vitronectin
WFDC1 WAP four-disulfide core domain 1
WFDC10A WAP four-disulfide core domain 10A
WFDC10B WAP four-disulfide core domain 10B
WFDC12 WAP four-disulfide core domain 12
WFDC13 WAP four-disulfide core domain 13
WFDC2 WAP four-disulfide core domain 2
WFDC3 WAP four-disulfide core domain 3
WFDC5 WAP four-disulfide core domain 5
WFDC8 WAP four-disulfide core domain 8
WFIKKN1 WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1
WFIKKN2 WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2
WNT9A wingless-type MMTV integration site family, member 9A
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase