negative regulation of mitotic cell cycle Gene Set

Dataset GO Biological Process Annotations
Category structural or functional annotations
Type biological process
Description Any process that stops, prevents or reduces the rate or extent of progression through the mitotic cell cycle. (Gene Ontology, GO_0045930)
External Link http://amigo.geneontology.org/amigo/term/GO:0045930
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Genes

215 genes participating in the negative regulation of mitotic cell cycle biological process from the curated GO Biological Process Annotations dataset.

Symbol Name
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ANAPC1 anaphase promoting complex subunit 1
ANAPC10 anaphase promoting complex subunit 10
ANAPC11 anaphase promoting complex subunit 11
ANAPC2 anaphase promoting complex subunit 2
ANAPC4 anaphase promoting complex subunit 4
ANAPC5 anaphase promoting complex subunit 5
ANAPC7 anaphase promoting complex subunit 7
APC adenomatous polyposis coli
ATF2 activating transcription factor 2
ATM ATM serine/threonine kinase
AURKAIP1 aurora kinase A interacting protein 1
BCL2 B-cell CLL/lymphoma 2
BCL2L1 BCL2-like 1
BLM Bloom syndrome, RecQ helicase-like
BMP4 bone morphogenetic protein 4
BMP7 bone morphogenetic protein 7
BRD7 bromodomain containing 7
BRINP1 bone morphogenetic protein/retinoic acid inducible neural-specific 1
BRINP2 bone morphogenetic protein/retinoic acid inducible neural-specific 2
BRINP3 bone morphogenetic protein/retinoic acid inducible neural-specific 3
BTG3 BTG family, member 3
BTG4 B-cell translocation gene 4
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B
BUB3 BUB3 mitotic checkpoint protein
C10ORF90 chromosome 10 open reading frame 90
CASP2 caspase 2, apoptosis-related cysteine peptidase
CCNA2 cyclin A2
CCND1 cyclin D1
CCNG1 cyclin G1
CDC16 cell division cycle 16
CDC20 cell division cycle 20
CDC23 cell division cycle 23
CDC26 cell division cycle 26
CDC27 cell division cycle 27
CDC73 cell division cycle 73
CDK1 cyclin-dependent kinase 1
CDK2 cyclin-dependent kinase 2
CDK5RAP3 CDK5 regulatory subunit associated protein 3
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
CENPF centromere protein F, 350/400kDa
CHEK1 checkpoint kinase 1
CHEK2 checkpoint kinase 2
CHFR checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase
CLSPN claspin
CRADD CASP2 and RIPK1 domain containing adaptor with death domain
CSNK2A1 casein kinase 2, alpha 1 polypeptide
CSNK2A2 casein kinase 2, alpha prime polypeptide
CTDSP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
CTDSP2 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2
CTDSPL CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
DACT1 dishevelled-binding antagonist of beta-catenin 1
DLG1 discs, large homolog 1 (Drosophila)
E2F7 E2F transcription factor 7
EGFR epidermal growth factor receptor
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
FBXO31 F-box protein 31
FBXO7 F-box protein 7
FGFR2 fibroblast growth factor receptor 2
FGFR3 fibroblast growth factor receptor 3
FHL1 four and a half LIM domains 1
FOXC1 forkhead box C1
FOXN3 forkhead box N3
FOXO4 forkhead box O4
FZD3 frizzled class receptor 3
GAS1 growth arrest-specific 1
GIGYF2 GRB10 interacting GYF protein 2
GML glycosylphosphatidylinositol anchored molecule like
GSG2 germ cell associated 2 (haspin)
GTSE1 G-2 and S-phase expressed 1
HMGA2 high mobility group AT-hook 2
HRAS Harvey rat sarcoma viral oncogene homolog
HUS1 HUS1 checkpoint homolog (S. pombe)
HUS1B HUS1 checkpoint homolog b (S. pombe)
IER3 immediate early response 3
INTS3 integrator complex subunit 3
JADE1 jade family PHD finger 1
KANK2 KN motif and ankyrin repeat domains 2
KLHL22 kelch-like family member 22
KNTC1 kinetochore associated 1
MAD1L1 MAD1 mitotic arrest deficient-like 1 (yeast)
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast)
MAD2L1BP MAD2L1 binding protein
MAD2L2 MAD2 mitotic arrest deficient-like 2 (yeast)
MBD4 methyl-CpG binding domain protein 4
MDC1 mediator of DNA-damage checkpoint 1
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MRE11A MRE11 meiotic recombination 11 homolog A (S. cerevisiae)
MSH2 mutS homolog 2
MTBP MDM2 binding protein
MUC1 mucin 1, cell surface associated
MYO16 myosin XVI
NABP1 nucleic acid binding protein 1
NABP2 nucleic acid binding protein 2
NACC2 NACC family member 2, BEN and BTB (POZ) domain containing
NAE1 NEDD8 activating enzyme E1 subunit 1
NBN nibrin
NEK11 NIMA-related kinase 11
NKX3-1 NK3 homeobox 1
NLE1 notchless homolog 1 (Drosophila)
NME6 NME/NM23 nucleoside diphosphate kinase 6
OVOL1 ovo-like zinc finger 1
PIDD1 p53-induced death domain protein 1
PKD2 polycystic kidney disease 2 (autosomal dominant)
PLK1 polo-like kinase 1
PLK2 polo-like kinase 2
PLK3 polo-like kinase 3
PML promyelocytic leukemia
PRCC papillary renal cell carcinoma (translocation-associated)
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PRMT2 protein arginine methyltransferase 2
PSMA1 proteasome (prosome, macropain) subunit, alpha type, 1
PSMA2 proteasome (prosome, macropain) subunit, alpha type, 2
PSMA3 proteasome (prosome, macropain) subunit, alpha type, 3
PSMA4 proteasome (prosome, macropain) subunit, alpha type, 4
PSMA5 proteasome (prosome, macropain) subunit, alpha type, 5
PSMA6 proteasome (prosome, macropain) subunit, alpha type, 6
PSMA7 proteasome (prosome, macropain) subunit, alpha type, 7
PSMA8 proteasome (prosome, macropain) subunit, alpha type, 8
PSMB1 proteasome (prosome, macropain) subunit, beta type, 1
PSMB10 proteasome (prosome, macropain) subunit, beta type, 10
PSMB11 proteasome (prosome, macropain) subunit, beta type, 11
PSMB2 proteasome (prosome, macropain) subunit, beta type, 2
PSMB3 proteasome (prosome, macropain) subunit, beta type, 3
PSMB4 proteasome (prosome, macropain) subunit, beta type, 4
PSMB5 proteasome (prosome, macropain) subunit, beta type, 5
PSMB6 proteasome (prosome, macropain) subunit, beta type, 6
PSMB7 proteasome (prosome, macropain) subunit, beta type, 7
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9
PSMC1 proteasome (prosome, macropain) 26S subunit, ATPase, 1
PSMC2 proteasome (prosome, macropain) 26S subunit, ATPase, 2
PSMC3 proteasome (prosome, macropain) 26S subunit, ATPase, 3
PSMC4 proteasome (prosome, macropain) 26S subunit, ATPase, 4
PSMC5 proteasome (prosome, macropain) 26S subunit, ATPase, 5
PSMC6 proteasome (prosome, macropain) 26S subunit, ATPase, 6
PSMD1 proteasome (prosome, macropain) 26S subunit, non-ATPase, 1
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
PSMD11 proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
PSMD12 proteasome (prosome, macropain) 26S subunit, non-ATPase, 12
PSMD13 proteasome (prosome, macropain) 26S subunit, non-ATPase, 13
PSMD14 proteasome (prosome, macropain) 26S subunit, non-ATPase, 14
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
PSMD3 proteasome (prosome, macropain) 26S subunit, non-ATPase, 3
PSMD4 proteasome (prosome, macropain) 26S subunit, non-ATPase, 4
PSMD5 proteasome (prosome, macropain) 26S subunit, non-ATPase, 5
PSMD6 proteasome (prosome, macropain) 26S subunit, non-ATPase, 6
PSMD7 proteasome (prosome, macropain) 26S subunit, non-ATPase, 7
PSMD8 proteasome (prosome, macropain) 26S subunit, non-ATPase, 8
PSMD9 proteasome (prosome, macropain) 26S subunit, non-ATPase, 9
PSME1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
PSME2 proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
PSME3 proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)
PSME4 proteasome (prosome, macropain) activator subunit 4
PSMF1 proteasome (prosome, macropain) inhibitor subunit 1 (PI31)
PSMG2 proteasome (prosome, macropain) assembly chaperone 2
PTEN phosphatase and tensin homolog
PTPN3 protein tyrosine phosphatase, non-receptor type 3
RAD17 RAD17 homolog (S. pombe)
RAD9A RAD9 homolog A (S. pombe)
RB1 retinoblastoma 1
RFWD2 ring finger and WD repeat domain 2, E3 ubiquitin protein ligase
RFWD3 ring finger and WD repeat domain 3
RGCC regulator of cell cycle
RPA2 replication protein A2, 32kDa
RPS27A ribosomal protein S27a
RPS27L ribosomal protein S27-like
RPS6 ribosomal protein S6
SCRIB scribbled planar cell polarity protein
SETMAR SET domain and mariner transposase fusion gene
SLFN11 schlafen family member 11
SMAD3 SMAD family member 3
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
SMC1A structural maintenance of chromosomes 1A
SOX4 SRY (sex determining region Y)-box 4
STIL SCL/TAL1 interrupting locus
SYF2 SYF2 pre-mRNA-splicing factor
TAOK3 TAO kinase 3
TEX14 testis expressed 14
TGFB1 transforming growth factor, beta 1
TICRR TOPBP1-interacting checkpoint and replication regulator
TIMP2 TIMP metallopeptidase inhibitor 2
TIPIN TIMELESS interacting protein
TOM1L1 target of myb1 (chicken)-like 1
TOM1L2 target of myb1-like 2 (chicken)
TOP2A topoisomerase (DNA) II alpha 170kDa
TOP2B topoisomerase (DNA) II beta 180kDa
TP53 tumor protein p53
TP63 tumor protein p63
TP73 tumor protein p73
TPR translocated promoter region, nuclear basket protein
TRIAP1 TP53 regulated inhibitor of apoptosis 1
TRIM35 tripartite motif containing 35
TRRAP transformation/transcription domain-associated protein
TTK TTK protein kinase
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1
UBB ubiquitin B
UBC ubiquitin C
UBE2C ubiquitin-conjugating enzyme E2C
UBE2D1 ubiquitin-conjugating enzyme E2D 1
UBE2E1 ubiquitin-conjugating enzyme E2E 1
USP17L2 ubiquitin specific peptidase 17-like family member 2
USP47 ubiquitin specific peptidase 47
WNT9A wingless-type MMTV integration site family, member 9A
XPC xeroderma pigmentosum, complementation group C
ZNF207 zinc finger protein 207
ZNF655 zinc finger protein 655
ZNF830 zinc finger protein 830
ZW10 zw10 kinetochore protein
ZWILCH zwilch kinetochore protein
ZWINT ZW10 interacting kinetochore protein