negative regulation of defense response Gene Set

Dataset GO Biological Process Annotations
Category structural or functional annotations
Type biological process
Description Any process that stops, prevents, or reduces the frequency, rate or extent of a defense response. (Gene Ontology, GO_0031348)
External Link http://amigo.geneontology.org/amigo/term/GO:0031348
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Genes

120 genes participating in the negative regulation of defense response biological process from the curated GO Biological Process Annotations dataset.

Symbol Name
A2M alpha-2-macroglobulin
ABR active BCR-related
ACP5 acid phosphatase 5, tartrate resistant
ADA adenosine deaminase
ADAR adenosine deaminase, RNA-specific
ADCYAP1 adenylate cyclase activating polypeptide 1 (pituitary)
ADIPOQ adiponectin, C1Q and collagen domain containing
ADORA1 adenosine A1 receptor
APCS amyloid P component, serum
APOA1 apolipoprotein A-I
APOD apolipoprotein D
APOE apolipoprotein E
ARRB2 arrestin, beta 2
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
BCR breakpoint cluster region
C1QBP complement component 1, q subcomponent binding protein
C1QTNF3 C1q and tumor necrosis factor related protein 3
CACTIN cactin, spliceosome C complex subunit
CALCRL calcitonin receptor-like
CD276 CD276 molecule
CHID1 chitinase domain containing 1
CNR2 cannabinoid receptor 2 (macrophage)
CR1 complement component (3b/4b) receptor 1 (Knops blood group)
DHX58 DEXH (Asp-Glu-X-His) box polypeptide 58
DUSP10 dual specificity phosphatase 10
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2
ELANE elastase, neutrophil expressed
FAM132A family with sequence similarity 132, member A
FEM1A fem-1 homolog a (C. elegans)
FFAR4 free fatty acid receptor 4
FOXF1 forkhead box F1
FOXP3 forkhead box P3
GATA3 GATA binding protein 3
GBA glucosidase, beta, acid
GHRL ghrelin/obestatin prepropeptide
GHSR growth hormone secretagogue receptor
GPER1 G protein-coupled estrogen receptor 1
GPX1 glutathione peroxidase 1
GPX2 glutathione peroxidase 2
GSTP1 glutathione S-transferase pi 1
HLA-E major histocompatibility complex, class I, E
HTRA1 HtrA serine peptidase 1
IER3 immediate early response 3
IFI16 interferon, gamma-inducible protein 16
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IL10 interleukin 10
IL12B interleukin 12B
IL2 interleukin 2
IL20RB interleukin 20 receptor beta
IL22RA2 interleukin 22 receptor, alpha 2
IL2RA interleukin 2 receptor, alpha
IL4 interleukin 4
INS insulin
IRAK3 interleukin-1 receptor-associated kinase 3
IRF3 interferon regulatory factor 3
IRG1 immunoresponsive 1 homolog (mouse)
ISL1 ISL LIM homeobox 1
ITCH itchy E3 ubiquitin protein ligase
KLF4 Kruppel-like factor 4 (gut)
KRT1 keratin 1, type II
LILRB1 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1
MAPK7 mitogen-activated protein kinase 7
MEFV Mediterranean fever
METRNL meteorin, glial cell differentiation regulator-like
MICA MHC class I polypeptide-related sequence A
MICB MHC class I polypeptide-related sequence B
MMP26 matrix metallopeptidase 26
MUL1 mitochondrial E3 ubiquitin protein ligase 1
MVK mevalonate kinase
NDFIP1 Nedd4 family interacting protein 1
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NLRC5 NLR family, CARD domain containing 5
NLRP12 NLR family, pyrin domain containing 12
NLRP3 NLR family, pyrin domain containing 3
NLRX1 NLR family member X1
NOD2 nucleotide-binding oligomerization domain containing 2
NR1H2 nuclear receptor subfamily 1, group H, member 2
NR1H3 nuclear receptor subfamily 1, group H, member 3
NT5E 5'-nucleotidase, ecto (CD73)
OTULIN OTU deubiquitinase with linear linkage specificity
PBK PDZ binding kinase
PCBP2 poly(rC) binding protein 2
PGLYRP1 peptidoglycan recognition protein 1
PPARD peroxisome proliferator-activated receptor delta
PPARG peroxisome proliferator-activated receptor gamma
PPM1B protein phosphatase, Mg2+/Mn2+ dependent, 1B
PRKCD protein kinase C, delta
PSMB4 proteasome (prosome, macropain) subunit, beta type, 4
PTGER4 prostaglandin E receptor 4 (subtype EP4)
PTGIS prostaglandin I2 (prostacyclin) synthase
PTPN2 protein tyrosine phosphatase, non-receptor type 2
RABGEF1 RAB guanine nucleotide exchange factor (GEF) 1
RORA RAR-related orphan receptor A
RPS19 ribosomal protein S19
SAA1 serum amyloid A1
SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
SHARPIN SHANK-associated RH domain interactor
SIRT2 sirtuin 2
SMAD3 SMAD family member 3
SOCS3 suppressor of cytokine signaling 3
TARBP2 TAR (HIV-1) RNA binding protein 2
TEK TEK tyrosine kinase, endothelial
TFF2 trefoil factor 2
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNFAIP6 tumor necrosis factor, alpha-induced protein 6
TNFAIP8L2 tumor necrosis factor, alpha-induced protein 8-like 2
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B
TRAF3IP1 TNF receptor-associated factor 3 interacting protein 1
TRAFD1 TRAF-type zinc finger domain containing 1
TRIM38 tripartite motif containing 38
TSPAN6 tetraspanin 6
TYRO3 TYRO3 protein tyrosine kinase
UACA uveal autoantigen with coiled-coil domains and ankyrin repeats
VIMP VCP-interacting membrane selenoprotein
ZFP36 ZFP36 ring finger protein