negative regulation of cell cycle Gene Set

Dataset GO Biological Process Annotations
Category structural or functional annotations
Type biological process
Description Any process that stops, prevents or reduces the rate or extent of progression through the cell cycle. (Gene Ontology, GO_0045786)
External Link http://amigo.geneontology.org/amigo/term/GO:0045786
Similar Terms
Downloads & Tools

Genes

431 genes participating in the negative regulation of cell cycle biological process from the curated GO Biological Process Annotations dataset.

Symbol Name
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ADCYAP1 adenylate cyclase activating polypeptide 1 (pituitary)
AK1 adenylate kinase 1
ALOX15B arachidonate 15-lipoxygenase, type B
ANAPC1 anaphase promoting complex subunit 1
ANAPC10 anaphase promoting complex subunit 10
ANAPC11 anaphase promoting complex subunit 11
ANAPC2 anaphase promoting complex subunit 2
ANAPC4 anaphase promoting complex subunit 4
ANAPC5 anaphase promoting complex subunit 5
ANAPC7 anaphase promoting complex subunit 7
APBB1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
APC adenomatous polyposis coli
ATF2 activating transcription factor 2
ATM ATM serine/threonine kinase
AURKA aurora kinase A
AURKAIP1 aurora kinase A interacting protein 1
AURKB aurora kinase B
BARD1 BRCA1 associated RING domain 1
BCL2 B-cell CLL/lymphoma 2
BCL2L1 BCL2-like 1
BLM Bloom syndrome, RecQ helicase-like
BMP2 bone morphogenetic protein 2
BMP4 bone morphogenetic protein 4
BMP7 bone morphogenetic protein 7
BRCA1 breast cancer 1, early onset
BRD7 bromodomain containing 7
BRINP1 bone morphogenetic protein/retinoic acid inducible neural-specific 1
BRINP2 bone morphogenetic protein/retinoic acid inducible neural-specific 2
BRINP3 bone morphogenetic protein/retinoic acid inducible neural-specific 3
BTG3 BTG family, member 3
BTG4 B-cell translocation gene 4
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B
BUB3 BUB3 mitotic checkpoint protein
C10ORF90 chromosome 10 open reading frame 90
C10ORF99 chromosome 10 open reading frame 99
CAB39 calcium binding protein 39
CAB39L calcium binding protein 39-like
CALR calreticulin
CASP2 caspase 2, apoptosis-related cysteine peptidase
CASP3 caspase 3, apoptosis-related cysteine peptidase
CCNA2 cyclin A2
CCND1 cyclin D1
CCNF cyclin F
CCNG1 cyclin G1
CCNK cyclin K
CDC123 cell division cycle 123
CDC16 cell division cycle 16
CDC20 cell division cycle 20
CDC23 cell division cycle 23
CDC26 cell division cycle 26
CDC27 cell division cycle 27
CDC5L cell division cycle 5-like
CDC73 cell division cycle 73
CDK1 cyclin-dependent kinase 1
CDK2 cyclin-dependent kinase 2
CDK4 cyclin-dependent kinase 4
CDK5 cyclin-dependent kinase 5
CDK5RAP1 CDK5 regulatory subunit associated protein 1
CDK5RAP2 CDK5 regulatory subunit associated protein 2
CDK5RAP3 CDK5 regulatory subunit associated protein 3
CDK6 cyclin-dependent kinase 6
CDK7 cyclin-dependent kinase 7
CDK9 cyclin-dependent kinase 9
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CDKN2A cyclin-dependent kinase inhibitor 2A
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CDKN3 cyclin-dependent kinase inhibitor 3
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CENPF centromere protein F, 350/400kDa
CGREF1 cell growth regulator with EF-hand domain 1
CGRRF1 cell growth regulator with ring finger domain 1
CHEK1 checkpoint kinase 1
CHEK2 checkpoint kinase 2
CHFR checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase
CHMP2A charged multivesicular body protein 2A
CHMP4C charged multivesicular body protein 4C
CLSPN claspin
CRADD CASP2 and RIPK1 domain containing adaptor with death domain
CSNK2A1 casein kinase 2, alpha 1 polypeptide
CSNK2A2 casein kinase 2, alpha prime polypeptide
CTDSP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
CTDSP2 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2
CTDSPL CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CUL1 cullin 1
CUL2 cullin 2
CUL3 cullin 3
CUL4A cullin 4A
CUL5 cullin 5
CXCL8 chemokine (C-X-C motif) ligand 8
DAB2IP DAB2 interacting protein
DACT1 dishevelled-binding antagonist of beta-catenin 1
DDIAS DNA damage-induced apoptosis suppressor
DDIT3 DNA-damage-inducible transcript 3
DDX39B DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B
DHCR24 24-dehydrocholesterol reductase
DLG1 discs, large homolog 1 (Drosophila)
DMRT1 doublesex and mab-3 related transcription factor 1
DST dystonin
DUSP1 dual specificity phosphatase 1
E2F7 E2F transcription factor 7
E2F8 E2F transcription factor 8
E4F1 E4F transcription factor 1
EGFR epidermal growth factor receptor
EIF4G2 eukaryotic translation initiation factor 4 gamma, 2
ERN1 endoplasmic reticulum to nucleus signaling 1
ERN2 endoplasmic reticulum to nucleus signaling 2
ESPL1 extra spindle pole bodies homolog 1 (S. cerevisiae)
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
FAP fibroblast activation protein, alpha
FBXO31 F-box protein 31
FBXO43 F-box protein 43
FBXO5 F-box protein 5
FBXO7 F-box protein 7
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FGF10 fibroblast growth factor 10
FGFR2 fibroblast growth factor receptor 2
FGFR3 fibroblast growth factor receptor 3
FHL1 four and a half LIM domains 1
FOXC1 forkhead box C1
FOXN3 forkhead box N3
FOXO4 forkhead box O4
FZD3 frizzled class receptor 3
GADD45A growth arrest and DNA-damage-inducible, alpha
GADD45GIP1 growth arrest and DNA-damage-inducible, gamma interacting protein 1
GAS1 growth arrest-specific 1
GAS2 growth arrest-specific 2
GAS2L1 growth arrest-specific 2 like 1
GAS2L2 growth arrest-specific 2 like 2
GAS2L3 growth arrest-specific 2 like 3
GAS6 growth arrest-specific 6
GAS7 growth arrest-specific 7
GATA3 GATA binding protein 3
GIGYF2 GRB10 interacting GYF protein 2
GML glycosylphosphatidylinositol anchored molecule like
GMNN geminin, DNA replication inhibitor
GPER1 G protein-coupled estrogen receptor 1
GSG2 germ cell associated 2 (haspin)
GTSE1 G-2 and S-phase expressed 1
H2AFY H2A histone family, member Y
HBP1 HMG-box transcription factor 1
HDAC1 histone deacetylase 1
HDAC2 histone deacetylase 2
HDAC3 histone deacetylase 3
HEPACAM hepatic and glial cell adhesion molecule
HEXIM1 hexamethylene bis-acetamide inducible 1
HEXIM2 hexamethylene bis-acetamide inducible 2
HHEX hematopoietically expressed homeobox
HMGA2 high mobility group AT-hook 2
HMGN5 high mobility group nucleosome binding domain 5
HORMAD1 HORMA domain containing 1
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
HRAS Harvey rat sarcoma viral oncogene homolog
HTRA2 HtrA serine peptidase 2
HUS1 HUS1 checkpoint homolog (S. pombe)
HUS1B HUS1 checkpoint homolog b (S. pombe)
IER3 immediate early response 3
IFNG interferon, gamma
IFNW1 interferon, omega 1
IL12A interleukin 12A
IL12B interleukin 12B
ILK integrin-linked kinase
INCA1 inhibitor of CDK, cyclin A1 interacting protein 1
ING4 inhibitor of growth family, member 4
INHA inhibin, alpha
INHBA inhibin, beta A
INTS3 integrator complex subunit 3
IRF1 interferon regulatory factor 1
IRF6 interferon regulatory factor 6
JADE1 jade family PHD finger 1
JMY junction mediating and regulatory protein, p53 cofactor
KANK2 KN motif and ankyrin repeat domains 2
KAT2B K(lysine) acetyltransferase 2B
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1
KIF20B kinesin family member 20B
KLHL22 kelch-like family member 22
KLLN killin, p53-regulated DNA replication inhibitor
KMT2E lysine (K)-specific methyltransferase 2E
KNTC1 kinetochore associated 1
LATS1 large tumor suppressor kinase 1
LATS2 large tumor suppressor kinase 2
LIF leukemia inhibitory factor
LILRB1 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1
MACF1 microtubule-actin crosslinking factor 1
MAD1L1 MAD1 mitotic arrest deficient-like 1 (yeast)
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast)
MAD2L1BP MAD2L1 binding protein
MAD2L2 MAD2 mitotic arrest deficient-like 2 (yeast)
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2
MAP2K1 mitogen-activated protein kinase kinase 1
MAP2K6 mitogen-activated protein kinase kinase 6
MAPK12 mitogen-activated protein kinase 12
MBD4 methyl-CpG binding domain protein 4
MCPH1 microcephalin 1
MDC1 mediator of DNA-damage checkpoint 1
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MDM4 MDM4, p53 regulator
MEN1 multiple endocrine neoplasia I
MFN2 mitofusin 2
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor)
MLF1 myeloid leukemia factor 1
MLXIPL MLX interacting protein-like
MOS v-mos Moloney murine sarcoma viral oncogene homolog
MRE11A MRE11 meiotic recombination 11 homolog A (S. cerevisiae)
MSH2 mutS homolog 2
MTBP MDM2 binding protein
MUC1 mucin 1, cell surface associated
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYO16 myosin XVI
MYOCD myocardin
NABP1 nucleic acid binding protein 1
NABP2 nucleic acid binding protein 2
NACC2 NACC family member 2, BEN and BTB (POZ) domain containing
NAE1 NEDD8 activating enzyme E1 subunit 1
NANOS2 nanos homolog 2 (Drosophila)
NBN nibrin
NEK11 NIMA-related kinase 11
NGF nerve growth factor (beta polypeptide)
NGFR nerve growth factor receptor
NKX3-1 NK3 homeobox 1
NLE1 notchless homolog 1 (Drosophila)
NME6 NME/NM23 nucleoside diphosphate kinase 6
NOTCH2 notch 2
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin)
NPPC natriuretic peptide C
NPR2 natriuretic peptide receptor 2
NR2F2 nuclear receptor subfamily 2, group F, member 2
NUBP1 nucleotide binding protein 1
NUPR1 nuclear protein, transcriptional regulator, 1
OSM oncostatin M
OVOL1 ovo-like zinc finger 1
PA2G4 proliferation-associated 2G4, 38kDa
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
PHOX2B paired-like homeobox 2b
PIDD1 p53-induced death domain protein 1
PKD1 polycystic kidney disease 1 (autosomal dominant)
PKD2 polycystic kidney disease 2 (autosomal dominant)
PLA2G16 phospholipase A2, group XVI
PLAGL1 pleiomorphic adenoma gene-like 1
PLK1 polo-like kinase 1
PLK2 polo-like kinase 2
PLK3 polo-like kinase 3
PML promyelocytic leukemia
PNPT1 polyribonucleotide nucleotidyltransferase 1
PPM1A protein phosphatase, Mg2+/Mn2+ dependent, 1A
PPM1G protein phosphatase, Mg2+/Mn2+ dependent, 1G
PPP1R13B protein phosphatase 1, regulatory subunit 13B
PPP1R15A protein phosphatase 1, regulatory subunit 15A
PPP1R9B protein phosphatase 1, regulatory subunit 9B
PRCC papillary renal cell carcinoma (translocation-associated)
PRDM4 PR domain containing 4
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit
PRKAB1 protein kinase, AMP-activated, beta 1 non-catalytic subunit
PRKAB2 protein kinase, AMP-activated, beta 2 non-catalytic subunit
PRKACB protein kinase, cAMP-dependent, catalytic, beta
PRKAG1 protein kinase, AMP-activated, gamma 1 non-catalytic subunit
PRKAG2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit
PRKAG3 protein kinase, AMP-activated, gamma 3 non-catalytic subunit
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PRMT2 protein arginine methyltransferase 2
PRNP prion protein
PRPF19 pre-mRNA processing factor 19
PSMA1 proteasome (prosome, macropain) subunit, alpha type, 1
PSMA2 proteasome (prosome, macropain) subunit, alpha type, 2
PSMA3 proteasome (prosome, macropain) subunit, alpha type, 3
PSMA4 proteasome (prosome, macropain) subunit, alpha type, 4
PSMA5 proteasome (prosome, macropain) subunit, alpha type, 5
PSMA6 proteasome (prosome, macropain) subunit, alpha type, 6
PSMA7 proteasome (prosome, macropain) subunit, alpha type, 7
PSMA8 proteasome (prosome, macropain) subunit, alpha type, 8
PSMB1 proteasome (prosome, macropain) subunit, beta type, 1
PSMB10 proteasome (prosome, macropain) subunit, beta type, 10
PSMB11 proteasome (prosome, macropain) subunit, beta type, 11
PSMB2 proteasome (prosome, macropain) subunit, beta type, 2
PSMB3 proteasome (prosome, macropain) subunit, beta type, 3
PSMB4 proteasome (prosome, macropain) subunit, beta type, 4
PSMB5 proteasome (prosome, macropain) subunit, beta type, 5
PSMB6 proteasome (prosome, macropain) subunit, beta type, 6
PSMB7 proteasome (prosome, macropain) subunit, beta type, 7
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9
PSMC1 proteasome (prosome, macropain) 26S subunit, ATPase, 1
PSMC2 proteasome (prosome, macropain) 26S subunit, ATPase, 2
PSMC3 proteasome (prosome, macropain) 26S subunit, ATPase, 3
PSMC4 proteasome (prosome, macropain) 26S subunit, ATPase, 4
PSMC5 proteasome (prosome, macropain) 26S subunit, ATPase, 5
PSMC6 proteasome (prosome, macropain) 26S subunit, ATPase, 6
PSMD1 proteasome (prosome, macropain) 26S subunit, non-ATPase, 1
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
PSMD11 proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
PSMD12 proteasome (prosome, macropain) 26S subunit, non-ATPase, 12
PSMD13 proteasome (prosome, macropain) 26S subunit, non-ATPase, 13
PSMD14 proteasome (prosome, macropain) 26S subunit, non-ATPase, 14
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
PSMD3 proteasome (prosome, macropain) 26S subunit, non-ATPase, 3
PSMD4 proteasome (prosome, macropain) 26S subunit, non-ATPase, 4
PSMD5 proteasome (prosome, macropain) 26S subunit, non-ATPase, 5
PSMD6 proteasome (prosome, macropain) 26S subunit, non-ATPase, 6
PSMD7 proteasome (prosome, macropain) 26S subunit, non-ATPase, 7
PSMD8 proteasome (prosome, macropain) 26S subunit, non-ATPase, 8
PSMD9 proteasome (prosome, macropain) 26S subunit, non-ATPase, 9
PSME1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
PSME2 proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
PSME3 proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)
PSME4 proteasome (prosome, macropain) activator subunit 4
PSMF1 proteasome (prosome, macropain) inhibitor subunit 1 (PI31)
PSMG2 proteasome (prosome, macropain) assembly chaperone 2
PTEN phosphatase and tensin homolog
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTPN3 protein tyrosine phosphatase, non-receptor type 3
PTPRK protein tyrosine phosphatase, receptor type, K
RAD1 RAD1 checkpoint DNA exonuclease
RAD17 RAD17 homolog (S. pombe)
RAD9A RAD9 homolog A (S. pombe)
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RB1 retinoblastoma 1
RFWD2 ring finger and WD repeat domain 2, E3 ubiquitin protein ligase
RFWD3 ring finger and WD repeat domain 3
RGCC regulator of cell cycle
RHEB Ras homolog enriched in brain
RHOB ras homolog family member B
RNF167 ring finger protein 167
RPA2 replication protein A2, 32kDa
RPRM reprimo, TP53 dependent G2 arrest mediator candidate
RPS27A ribosomal protein S27a
RPS27L ribosomal protein S27-like
RPS6 ribosomal protein S6
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2
RPTOR regulatory associated protein of MTOR, complex 1
RUNX3 runt-related transcription factor 3
SART1 squamous cell carcinoma antigen recognized by T cells
SCRIB scribbled planar cell polarity protein
SESN1 sestrin 1
SETMAR SET domain and mariner transposase fusion gene
SGSM3 small G protein signaling modulator 3
SIPA1 signal-induced proliferation-associated 1
SKIL SKI-like proto-oncogene
SLFN11 schlafen family member 11
SMAD3 SMAD family member 3
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
SMC1A structural maintenance of chromosomes 1A
SMC3 structural maintenance of chromosomes 3
SOX11 SRY (sex determining region Y)-box 11
SOX2 SRY (sex determining region Y)-box 2
SOX4 SRY (sex determining region Y)-box 4
STAG2 stromal antigen 2
STIL SCL/TAL1 interrupting locus
STK11 serine/threonine kinase 11
STRA8 stimulated by retinoic acid 8
STRADA STE20-related kinase adaptor alpha
STRADB STE20-related kinase adaptor beta
SUSD2 sushi domain containing 2
SYF2 SYF2 pre-mRNA-splicing factor
TAF6 TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
TAOK3 TAO kinase 3
TBRG1 transforming growth factor beta regulator 1
TBRG4 transforming growth factor beta regulator 4
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TERF1 telomeric repeat binding factor (NIMA-interacting) 1
TERF2 telomeric repeat binding factor 2
TEX14 testis expressed 14
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TGFB1 transforming growth factor, beta 1
TGFB2 transforming growth factor, beta 2
TGFBR1 transforming growth factor, beta receptor 1
THAP5 THAP domain containing 5
THBS1 thrombospondin 1
THOC1 THO complex 1
THOC5 THO complex 5
TICRR TOPBP1-interacting checkpoint and replication regulator
TIMP2 TIMP metallopeptidase inhibitor 2
TIPIN TIMELESS interacting protein
TMEM67 transmembrane protein 67
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TOM1L1 target of myb1 (chicken)-like 1
TOM1L2 target of myb1-like 2 (chicken)
TOP2A topoisomerase (DNA) II alpha 170kDa
TOP2B topoisomerase (DNA) II beta 180kDa
TP53 tumor protein p53
TP53BP2 tumor protein p53 binding protein 2
TP53INP1 tumor protein p53 inducible nuclear protein 1
TP63 tumor protein p63
TP73 tumor protein p73
TPR translocated promoter region, nuclear basket protein
TRIAP1 TP53 regulated inhibitor of apoptosis 1
TRIM35 tripartite motif containing 35
TRIM37 tripartite motif containing 37
TRRAP transformation/transcription domain-associated protein
TSC1 tuberous sclerosis 1
TSC2 tuberous sclerosis 2
TSG101 tumor susceptibility 101
TSPYL2 TSPY-like 2
TTK TTK protein kinase
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1
UBB ubiquitin B
UBC ubiquitin C
UBE2C ubiquitin-conjugating enzyme E2C
UBE2D1 ubiquitin-conjugating enzyme E2D 1
UBE2E1 ubiquitin-conjugating enzyme E2E 1
UHMK1 U2AF homology motif (UHM) kinase 1
USP17L2 ubiquitin specific peptidase 17-like family member 2
USP47 ubiquitin specific peptidase 47
VASH1 vasohibin 1
VPS4A vacuolar protein sorting 4 homolog A (S. cerevisiae)
WAPAL wings apart-like homolog (Drosophila)
WDR6 WD repeat domain 6
WEE2 WEE1 homolog 2 (S. pombe)
WNT10B wingless-type MMTV integration site family, member 10B
WNT9A wingless-type MMTV integration site family, member 9A
XPC xeroderma pigmentosum, complementation group C
ZAK sterile alpha motif and leucine zipper containing kinase AZK
ZBTB17 zinc finger and BTB domain containing 17
ZFHX3 zinc finger homeobox 3
ZFYVE19 zinc finger, FYVE domain containing 19
ZNF207 zinc finger protein 207
ZNF268 zinc finger protein 268
ZNF655 zinc finger protein 655
ZNF830 zinc finger protein 830
ZNHIT1 zinc finger, HIT-type containing 1
ZW10 zw10 kinetochore protein
ZWILCH zwilch kinetochore protein
ZWINT ZW10 interacting kinetochore protein