negative regulation of apoptotic signaling pathway Gene Set

Dataset GO Biological Process Annotations
Category structural or functional annotations
Type biological process
Description Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic signaling pathway. (Gene Ontology, GO_2001234)
External Link http://amigo.geneontology.org/amigo/term/GO:2001234
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Genes

195 genes participating in the negative regulation of apoptotic signaling pathway biological process from the curated GO Biological Process Annotations dataset.

Symbol Name
ACAA2 acetyl-CoA acyltransferase 2
ACKR3 atypical chemokine receptor 3
ACVR1 activin A receptor, type I
AKT1 v-akt murine thymoma viral oncogene homolog 1
AR androgen receptor
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
ARRB2 arrestin, beta 2
AVP arginine vasopressin
BAG5 BCL2-associated athanogene 5
BAX BCL2-associated X protein
BCL2 B-cell CLL/lymphoma 2
BCL2A1 BCL2-related protein A1
BCL2L1 BCL2-like 1
BCL2L10 BCL2-like 10 (apoptosis facilitator)
BCL2L12 BCL2-like 12 (proline rich)
BCL2L2 BCL2-like 2
BDKRB2 bradykinin receptor B2
BIRC6 baculoviral IAP repeat containing 6
BMF Bcl2 modifying factor
BMP5 bone morphogenetic protein 5
BRCA1 breast cancer 1, early onset
CCAR2 cell cycle and apoptosis regulator 2
CD44 CD44 molecule (Indian blood group)
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CFLAR CASP8 and FADD-like apoptosis regulator
CLU clusterin
COL2A1 collagen, type II, alpha 1
CREB3 cAMP responsive element binding protein 3
CREB3L1 cAMP responsive element binding protein 3-like 1
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
CTH cystathionine gamma-lyase
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTTN cortactin
CX3CL1 chemokine (C-X3-C motif) ligand 1
CX3CR1 chemokine (C-X3-C motif) receptor 1
CXCL12 chemokine (C-X-C motif) ligand 12
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
DAPK1 death-associated protein kinase 1
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
ELL3 elongation factor RNA polymerase II-like 3
EPO erythropoietin
EYA1 EYA transcriptional coactivator and phosphatase 1
FAIM2 Fas apoptotic inhibitory molecule 2
FGA fibrinogen alpha chain
FGB fibrinogen beta chain
FGF10 fibroblast growth factor 10
FGG fibrinogen gamma chain
FIGNL1 fidgetin-like 1
FXN frataxin
FYN FYN proto-oncogene, Src family tyrosine kinase
G2E3 G2/M-phase specific E3 ubiquitin protein ligase
GAS1 growth arrest-specific 1
GATA1 GATA binding protein 1 (globin transcription factor 1)
GCG glucagon
GCLC glutamate-cysteine ligase, catalytic subunit
GCLM glutamate-cysteine ligase, modifier subunit
GDNF glial cell derived neurotrophic factor
GFRAL GDNF family receptor alpha like
GPX1 glutathione peroxidase 1
GRINA glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)
GSTP1 glutathione S-transferase pi 1
HDAC2 histone deacetylase 2
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HIGD1A HIG1 hypoxia inducible domain family, member 1A
HMGB2 high mobility group box 2
HMOX1 heme oxygenase 1
HSPB1 heat shock 27kDa protein 1
HTRA2 HtrA serine peptidase 2
HTT huntingtin
HYOU1 hypoxia up-regulated 1
ICAM1 intercellular adhesion molecule 1
IER3 immediate early response 3
IFI6 interferon, alpha-inducible protein 6
IGBP1 immunoglobulin (CD79A) binding protein 1
IGF1 insulin-like growth factor 1 (somatomedin C)
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
IL19 interleukin 19
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL4 interleukin 4
IL7 interleukin 7
ING2 inhibitor of growth family, member 2
INS insulin
ITGA6 integrin, alpha 6
ITGAV integrin, alpha V
IVNS1ABP influenza virus NS1A binding protein
KDM1A lysine (K)-specific demethylase 1A
KIAA1324 KIAA1324
LGALS3 lectin, galactoside-binding, soluble, 3
LMNA lamin A/C
LRRK2 leucine-rich repeat kinase 2
MADD MAP-kinase activating death domain
MAP2K5 mitogen-activated protein kinase kinase 5
MAP3K7 mitogen-activated protein kinase kinase kinase 7
MAPK7 mitogen-activated protein kinase 7
MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1
MCL1 myeloid cell leukemia 1
MEIS3 Meis homeobox 3
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor)
MKL1 megakaryoblastic leukemia (translocation) 1
MMP9 matrix metallopeptidase 9
MNT MAX network transcriptional repressor
MPV17L MPV17 mitochondrial membrane protein-like
MUC1 mucin 1, cell surface associated
NANOS3 nanos homolog 3 (Drosophila)
NDUFA13 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13
NDUFS3 NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase)
NFE2L2 nuclear factor, erythroid 2-like 2
NLE1 notchless homolog 1 (Drosophila)
NME5 NME/NM23 family member 5
NOC2L nucleolar complex associated 2 homolog (S. cerevisiae)
NOG noggin
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain)
NONO non-POU domain containing, octamer-binding
NOS3 nitric oxide synthase 3 (endothelial cell)
NRP1 neuropilin 1
OPA1 optic atrophy 1 (autosomal dominant)
PAK7 p21 protein (Cdc42/Rac)-activated kinase 7
PARK2 parkin RBR E3 ubiquitin protein ligase
PARK7 parkinson protein 7
PARL presenilin associated, rhomboid-like
PCGF2 polycomb group ring finger 2
PDX1 pancreatic and duodenal homeobox 1
PEA15 phosphoprotein enriched in astrocytes 15
PELI3 pellino E3 ubiquitin protein ligase family member 3
PF4 platelet factor 4
PGAP2 post-GPI attachment to proteins 2
PHIP pleckstrin homology domain interacting protein
PINK1 PTEN induced putative kinase 1
PLAUR plasminogen activator, urokinase receptor
PPIF peptidylprolyl isomerase F
PRELID1 PRELI domain containing 1
PSEN1 presenilin 1
PSEN2 presenilin 2
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
PSME3 proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RB1CC1 RB1-inducible coiled-coil 1
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RFFL ring finger and FYVE-like domain containing E3 ubiquitin protein ligase
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
RNF34 ring finger protein 34, E3 ubiquitin protein ligase
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
RRM2B ribonucleotide reductase M2 B (TP53 inducible)
RRN3 RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae)
SCG2 secretogranin II
SCRT2 scratch family zinc finger 2
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SFRP2 secreted frizzled-related protein 2
SGMS1 sphingomyelin synthase 1
SH3RF1 SH3 domain containing ring finger 1
SIAH2 siah E3 ubiquitin protein ligase 2
SIRT1 sirtuin 1
SLC25A5 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5
SLC35F6 solute carrier family 35, member F6
SNAI1 snail family zinc finger 1
SNAI2 snail family zinc finger 2
SOD2 superoxide dismutase 2, mitochondrial
SRC SRC proto-oncogene, non-receptor tyrosine kinase
ST20 suppressor of tumorigenicity 20
STRADB STE20-related kinase adaptor beta
SYVN1 synovial apoptosis inhibitor 1, synoviolin
TAF9 TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa
TAF9B TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TERT telomerase reverse transcriptase
TGFBR1 transforming growth factor, beta receptor 1
THBS1 thrombospondin 1
TMBIM1 transmembrane BAX inhibitor motif containing 1
TMBIM6 transmembrane BAX inhibitor motif containing 6
TMEM161A transmembrane protein 161A
TNF tumor necrosis factor
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TPT1 tumor protein, translationally-controlled 1
TRAP1 TNF receptor-associated protein 1
TRIAP1 TP53 regulated inhibitor of apoptosis 1
TRIM32 tripartite motif containing 32
UNC5B unc-5 homolog B (C. elegans)
URI1 URI1, prefoldin-like chaperone
USP47 ubiquitin specific peptidase 47
VDAC2 voltage-dependent anion channel 2
VIMP VCP-interacting membrane selenoprotein
VNN1 vanin 1
WFS1 Wolfram syndrome 1 (wolframin)
WNT4 wingless-type MMTV integration site family, member 4
XBP1 X-box binding protein 1
YAP1 Yes-associated protein 1
YBX3 Y box binding protein 3
ZC3HC1 zinc finger, C3HC-type containing 1
ZMYND11 zinc finger, MYND-type containing 11
ZNF385A zinc finger protein 385A