nci-h226br cell Gene Set

Dataset TISSUES Text-mining Tissue Protein Expression Evidence Scores
Category structural or functional annotations
Type tissue
Description The H226Br cell line is a variant of the NCI-H226 cell line derived from a brain metastasis in a nu/nu mouse. (BRENDA Tissue and Enzyme Source Ontology, BTO_0000171)
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Genes

308 proteins co-occuring with the tissue nci-h226br cell in abstracts of biomedical publications from the TISSUES Text-mining Tissue Protein Expression Evidence Scores dataset.

Symbol Name Standardized Value
GCG glucagon 2.35024
PYY peptide YY 2.10219
GPR119 G protein-coupled receptor 119 1.81124
GLP1R glucagon-like peptide 1 receptor 1.79094
DPP4 dipeptidyl-peptidase 4 1.66857
GPBAR1 G protein-coupled bile acid receptor 1 1.65407
SCP2 sterol carrier protein 2 1.59572
DHDH dihydrodiol dehydrogenase (dimeric) 1.58338
GIP gastric inhibitory polypeptide 1.51522
INS insulin 1.45053
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 1.3201
PVRL1 poliovirus receptor-related 1 (herpesvirus entry mediator C) 1.24342
CD40 CD40 molecule, TNF receptor superfamily member 5 1.23807
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 1.22469
GLP2R glucagon-like peptide 2 receptor 1.1687
CD40LG CD40 ligand 1.15894
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 1.14476
PCSK1 proprotein convertase subtilisin/kexin type 1 1.1173
WNT3A wingless-type MMTV integration site family, member 3A 1.07353
STC1 stanniocalcin 1 1.06382
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast) 1.05501
ICAM1 intercellular adhesion molecule 1 1.02469
FFAR2 free fatty acid receptor 2 1.00414
CD4 CD4 molecule 1.0024
FFAR4 free fatty acid receptor 4 1.00196
JUP junction plakoglobin 0.97935
ADCY2 adenylate cyclase 2 (brain) 0.963767
B4GALT7 xylosylprotein beta 1,4-galactosyltransferase, polypeptide 7 0.960744
HLA-A major histocompatibility complex, class I, A 0.951685
CDH2 cadherin 2, type 1, N-cadherin (neuronal) 0.919916
TAS2R9 taste receptor, type 2, member 9 0.875706
LPO lactoperoxidase 0.863891
SST somatostatin 0.863048
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box) 0.85505
CD58 CD58 molecule 0.852106
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11 0.845805
GNAT3 guanine nucleotide binding protein, alpha transducing 3 0.821085
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.808551
HLA-B major histocompatibility complex, class I, B 0.803961
CD80 CD80 molecule 0.803127
ST6GALNAC3 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 0.802293
PCSK2 proprotein convertase subtilisin/kexin type 2 0.781894
RNASEH2A ribonuclease H2, subunit A 0.759914
SCGB1D2 secretoglobin, family 1D, member 2 0.75247
PVR poliovirus receptor 0.75247
CCK cholecystokinin 0.74834
GRP gastrin-releasing peptide 0.728152
IL2 interleukin 2 0.719524
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.714189
LYZ lysozyme 0.711319
PPY pancreatic polypeptide 0.706812
IFNA1 interferon, alpha 1 0.705583
ALB albumin 0.696581
DSG3 desmoglein 3 0.690451
RAPGEF4 Rap guanine nucleotide exchange factor (GEF) 4 0.688817
AXIN1 axin 1 0.688817
HPRT1 hypoxanthine phosphoribosyltransferase 1 0.687184
GHRL ghrelin/obestatin prepropeptide 0.685143
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase 0.6721
SCARF1 scavenger receptor class F, member 1 0.664775
ADRB2 adrenoceptor beta 2, surface 0.663149
B2M beta-2-microglobulin 0.661523
A4GALT alpha 1,4-galactosyltransferase 0.659085
PNO1 partner of NOB1 homolog (S. cerevisiae) 0.649344
TJP1 tight junction protein 1 0.646505
TNF tumor necrosis factor 0.644479
ACTG1 actin gamma 1 0.640833
THY1 Thy-1 cell surface antigen 0.639619
MGAM maltase-glucoamylase 0.635976
CSGALNACT2 chondroitin sulfate N-acetylgalactosaminyltransferase 2 0.630718
DSG1 desmoglein 1 0.627081
NGF nerve growth factor (beta polypeptide) 0.626273
FKBP4 FK506 binding protein 4, 59kDa 0.621024
IFNB1 interferon, beta 1, fibroblast 0.620217
SLC25A18 solute carrier family 25 (glutamate carrier), member 18 0.619814
LPAR5 lysophosphatidic acid receptor 5 0.618603
ICAM2 intercellular adhesion molecule 2 0.61699
MYOM3 myomesin 3 0.614974
CCDC88C coiled-coil domain containing 88C 0.60249
NKAIN2 Na+/K+ transporting ATPase interacting 2 0.598067
BVES blood vessel epicardial substance 0.597263
FN1 fibronectin 1 0.589635
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class) 0.588031
DVL1 dishevelled segment polarity protein 1 0.584422
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) 0.581218
ICAM4 intercellular adhesion molecule 4 (Landsteiner-Wiener blood group) 0.576015
DNAH8 dynein, axonemal, heavy chain 8 0.574017
ACTB actin, beta 0.572018
CD44 CD44 molecule (Indian blood group) 0.57082
CD3D CD3d molecule, delta (CD3-TCR complex) 0.565631
ACAA1 acetyl-CoA acyltransferase 1 0.56284
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) 0.56005
CSF1 colony stimulating factor 1 (macrophage) 0.558457
GPRC6A G protein-coupled receptor, class C, group 6, member A 0.558059
FFAR1 free fatty acid receptor 1 0.55607
TCF7 transcription factor 7 (T-cell specific, HMG-box) 0.555274
ACPP acid phosphatase, prostate 0.55408
HSPA4 heat shock 70kDa protein 4 0.55408
CHRM3 cholinergic receptor, muscarinic 3 0.552093
ACAA2 acetyl-CoA acyltransferase 2 0.550503
GCGR glucagon receptor 0.549709
SELE selectin E 0.546136
CD99L2 CD99 molecule-like 2 0.546136
SELL selectin L 0.544549
AVIL advillin 0.544152
MARS2 methionyl-tRNA synthetase 2, mitochondrial 0.543359
NCAM1 neural cell adhesion molecule 1 0.542566
IGLV3-19 immunoglobulin lambda variable 3-19 0.537021
IL3 interleukin 3 0.536229
CDH4 cadherin 4, type 1, R-cadherin (retinal) 0.533065
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial 0.532274
NTS neurotensin 0.531484
PDE12 phosphodiesterase 12 0.528323
GAST gastrin 0.527928
CD5 CD5 molecule 0.521223
BNIPL BCL2/adenovirus E1B 19kD interacting protein like 0.519253
HLA-DRB4 major histocompatibility complex, class II, DR beta 4 0.518072
CD2 CD2 molecule 0.517678
WDR13 WD repeat domain 13 0.514136
IGIP IgA-inducing protein 0.512564
PRTG protogenin 0.512171
IFNA6 interferon, alpha 6 0.505887
DSP desmoplakin 0.496483
ST6GALNAC5 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 0.494528
MDK midkine (neurite growth-promoting factor 2) 0.494136
FTH1 ferritin, heavy polypeptide 1 0.493354
WDR11 WD repeat domain 11 0.485156
PPID peptidylprolyl isomerase D 0.485156
ADGRG6 adhesion G protein-coupled receptor G6 0.48048
APRT adenine phosphoribosyltransferase 0.48048
PTPRG protein tyrosine phosphatase, receptor type, G 0.472704
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) 0.470375
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) 0.469987
CADM1 cell adhesion molecule 1 0.466885
FZD5 frizzled class receptor 5 0.466498
FAS Fas cell surface death receptor 0.465723
TFRC transferrin receptor 0.465335
BHMT2 betaine--homocysteine S-methyltransferase 2 0.464174
AP1S1 adaptor-related protein complex 1, sigma 1 subunit 0.460692
PTPN1 protein tyrosine phosphatase, non-receptor type 1 0.459918
PCDH19 protocadherin 19 0.456828
IFNG interferon, gamma 0.456828
NPY neuropeptide Y 0.454512
KCNA5 potassium channel, voltage gated shaker related subfamily A, member 5 0.448346
POMC proopiomelanocortin 0.444884
PAX4 paired box 4 0.437972
IGSF5 immunoglobulin superfamily, member 5 0.43414
TPI1 triosephosphate isomerase 1 0.428018
MRAP melanocortin 2 receptor accessory protein 0.422673
PNMA6A paraneoplastic Ma antigen family member 6A 0.420385
DNASE1 deoxyribonuclease I 0.419242
SENP3 SUMO1/sentrin/SMT3 specific peptidase 3 0.418861
CDH5 cadherin 5, type 2 (vascular endothelium) 0.418861
FTL ferritin, light polypeptide 0.41848
IL4 interleukin 4 0.415434
FKBP5 FK506 binding protein 5 0.41087
LHCGR luteinizing hormone/choriogonadotropin receptor 0.41087
SFRP2 secreted frizzled-related protein 2 0.408972
GP9 glycoprotein IX (platelet) 0.404797
SCGB1D1 secretoglobin, family 1D, member 1 0.404418
NTPCR nucleoside-triphosphatase, cancer-related 0.398735
NEUROD1 neuronal differentiation 1 0.394953
NR1H4 nuclear receptor subfamily 1, group H, member 4 0.394197
AK2 adenylate kinase 2 0.391176
CASD1 CAS1 domain containing 1 0.384766
TSHB thyroid stimulating hormone, beta 0.38439
GIPR gastric inhibitory polypeptide receptor 0.38326
PCDH12 protocadherin 12 0.382884
AMOTL1 angiomotin like 1 0.382884
PRAMEF20 PRAME family member 20 0.380251
GCK glucokinase (hexokinase 4) 0.379875
ECI2 enoyl-CoA delta isomerase 2 0.377621
NRCAM neuronal cell adhesion molecule 0.377621
IFNA4 interferon, alpha 4 0.377245
CD8A CD8a molecule 0.37687
FFAR3 free fatty acid receptor 3 0.373118
RSPO3 R-spondin 3 0.372743
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.369373
HIST1H3F histone cluster 1, H3f 0.368998
HIST1H3J histone cluster 1, H3j 0.368998
HIST1H3G histone cluster 1, H3g 0.368998
HIST1H3I histone cluster 1, H3i 0.368998
HIST1H3D histone cluster 1, H3d 0.368998
HDLBP high density lipoprotein binding protein 0.368624
HIST1H3B histone cluster 1, H3b 0.36825
EIF4B eukaryotic translation initiation factor 4B 0.362273
NEUROG3 neurogenin 3 0.360036
CENPV centromere protein V 0.358546
ALPPL2 alkaline phosphatase, placental-like 2 0.357802
CD9 CD9 molecule 0.35743
ALPL alkaline phosphatase, liver/bone/kidney 0.35743
ALPP alkaline phosphatase, placental 0.356686
CHSY1 chondroitin sulfate synthase 1 0.356314
ERVW-1 endogenous retrovirus group W, member 1 0.354455
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 0.35334
EMB embigin 0.345928
OCLN occludin 0.344818
MC4R melanocortin 4 receptor 0.342971
SLC2A2 solute carrier family 2 (facilitated glucose transporter), member 2 0.341126
SLC10A3 solute carrier family 10, member 3 0.341126
HLA-G major histocompatibility complex, class I, G 0.336336
NCKAP1 NCK-associated protein 1 0.334498
EPCAM epithelial cell adhesion molecule 0.333396
CREB1 cAMP responsive element binding protein 1 0.331927
HIST1H3E histone cluster 1, H3e 0.331194
PVRL2 poliovirus receptor-related 2 (herpesvirus entry mediator B) 0.325335
PLIN2 perilipin 2 0.324605
HBA1 hemoglobin, alpha 1 0.322414
CHGA chromogranin A 0.319134
PAX6 paired box 6 0.31877
IGF2R insulin-like growth factor 2 receptor 0.31877
HIST1H3C histone cluster 1, H3c 0.317679
HIST1H3H histone cluster 1, H3h 0.317315
KCNB1 potassium channel, voltage gated Shab related subfamily B, member 1 0.316588
LCTL lactase-like 0.313683
GUSB glucuronidase, beta 0.312595
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) 0.312595
CSAG3 CSAG family, member 3 0.312232
CSAG2 CSAG family, member 2 0.312232
CASR calcium-sensing receptor 0.31187
PCDH7 protocadherin 7 0.311507
HIST1H3A histone cluster 1, H3a 0.311145
HBA2 hemoglobin, alpha 2 0.310783
FLII flightless I homolog (Drosophila) 0.310421
PDCD2 programmed cell death 2 0.305361
SFRP1 secreted frizzled-related protein 1 0.305361
CD8B CD8b molecule 0.30464
IL2RA interleukin 2 receptor, alpha 0.302838
ACKR1 atypical chemokine receptor 1 (Duffy blood group) 0.302478
PNP purine nucleoside phosphorylase 0.302478
IGLV5-48 immunoglobulin lambda variable 5-48 (non-functional) 0.300679
CDC42 cell division cycle 42 0.29673
DBN1 drebrin 1 0.296013
C2 complement component 2 0.295655
OPTC opticin 0.294581
HLA-E major histocompatibility complex, class I, E 0.293508
STX5 syntaxin 5 0.292436
VAMP4 vesicle-associated membrane protein 4 0.292079
RXFP4 relaxin/insulin-like family peptide receptor 4 0.290295
INSL5 insulin-like 5 0.290295
GYLTL1B glycosyltransferase-like 1B 0.289226
CROCC ciliary rootlet coiled-coil, rootletin 0.289226
PLK2 polo-like kinase 2 0.288158
FOS FBJ murine osteosarcoma viral oncogene homolog 0.287803
AMICA1 adhesion molecule, interacts with CXADR antigen 1 0.284253
GSK3B glycogen synthase kinase 3 beta 0.283899
PCDH11Y protocadherin 11 Y-linked 0.282837
CPE carboxypeptidase E 0.282837
CALM3 calmodulin 3 (phosphorylase kinase, delta) 0.280012
CALM2 calmodulin 2 (phosphorylase kinase, delta) 0.279659
CALM1 calmodulin 1 (phosphorylase kinase, delta) 0.278603
CD38 CD38 molecule 0.275444
IRS2 insulin receptor substrate 2 0.274045
PIGG phosphatidylinositol glycan anchor biosynthesis, class G 0.274045
PNMA2 paraneoplastic Ma antigen 2 0.2723
PAQR7 progestin and adipoQ receptor family member VII 0.271952
PCDH11X protocadherin 11 X-linked 0.270909
TAS2R38 taste receptor, type 2, member 38 0.269867
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1 0.267102
MCAM melanoma cell adhesion molecule 0.267102
HLA-DPB1 major histocompatibility complex, class II, DP beta 1 0.264696
CD72 CD72 molecule 0.264353
FRAT1 frequently rearranged in advanced T-cell lymphomas 1 0.264011
BTNL2 butyrophilin-like 2 0.263669
KIF20A kinesin family member 20A 0.262986
GPR176 G protein-coupled receptor 176 0.260606
ADK adenosine kinase 0.2559
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 0.254902
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 0.25457
IQGAP1 IQ motif containing GTPase activating protein 1 0.252919
B4GALT6 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6 0.25259
DSC3 desmocollin 3 0.250953
GSTM1 glutathione S-transferase mu 1 0.249977
GUK1 guanylate kinase 1 0.248683
FAF1 Fas (TNFRSF6) associated factor 1 0.24804
HLA-DRB5 major histocompatibility complex, class II, DR beta 5 0.247719
TMPRSS13 transmembrane protease, serine 13 0.247079
TSHR thyroid stimulating hormone receptor 0.24676
TPGS2 tubulin polyglutamylase complex subunit 2 0.24676
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2 0.24676
PARD6A par-6 family cell polarity regulator alpha 0.241132
ADA adenosine deaminase 0.241132
CTSD cathepsin D 0.23459
RBMS2 RNA binding motif, single stranded interacting protein 2 0.233446
LPP LIM domain containing preferred translocation partner in lipoma 0.232317
VCL vinculin 0.232039
EPRS glutamyl-prolyl-tRNA synthetase 0.23011
HBEGF heparin-binding EGF-like growth factor 0.229839
SPTA1 spectrin, alpha, erythrocytic 1 0.229568
LIG1 ligase I, DNA, ATP-dependent 0.228234
PCDH1 protocadherin 1 0.22797
IFNA21 interferon, alpha 21 0.226667
TOM1 target of myb1 (chicken) 0.224398
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2 0.223906
ESR1 estrogen receptor 1 0.220831
BNIP2 BCL2/adenovirus E1B 19kDa interacting protein 2 0.219264
FSHR follicle stimulating hormone receptor 0.219264
KTN1 kinectin 1 (kinesin receptor) 0.219264
ANOS1 anosmin 1 0.218613
AP1M2 adaptor-related protein complex 1, mu 2 subunit 0.218398
RAB13 RAB13, member RAS oncogene family 0.218398
CAMLG calcium modulating ligand 0.218186
MBP myelin basic protein 0.217346
WNT1 wingless-type MMTV integration site family, member 1 0.216325
DLAT dihydrolipoamide S-acetyltransferase 0.215928
CFH complement factor H 0.214765
HMGCL 3-hydroxymethyl-3-methylglutaryl-CoA lyase 0.214576
IFNA17 interferon, alpha 17 0.214202