natamycin-7167 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

194 genes differentially expressed following the natamycin-7167 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
AASS aminoadipate-semialdehyde synthase
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ACSL5 acyl-CoA synthetase long-chain family member 5
ADGRF5 adhesion G protein-coupled receptor F5
AHI1 Abelson helper integration site 1
AKAP12 A kinase (PRKA) anchor protein 12
BAZ1B bromodomain adjacent to zinc finger domain, 1B
BRF2 BRF2, RNA polymerase III transcription initiation factor 50 kDa subunit
C14ORF93 chromosome 14 open reading frame 93
CACNB4 calcium channel, voltage-dependent, beta 4 subunit
CASP2 caspase 2, apoptosis-related cysteine peptidase
CCDC33 coiled-coil domain containing 33
CCNO cyclin O
CD36 CD36 molecule (thrombospondin receptor)
CD52 CD52 molecule
CDH8 cadherin 8, type 2
DOC2A double C2-like domains, alpha
EDRF1 erythroid differentiation regulatory factor 1
EGR3 early growth response 3
EPHA1 EPH receptor A1
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
FAM212B family with sequence similarity 212, member B
FBXO21 F-box protein 21
GIPR gastric inhibitory polypeptide receptor
GRIA3 glutamate receptor, ionotropic, AMPA 3
HSPB3 heat shock 27kDa protein 3
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IDS iduronate 2-sulfatase
IFT140 intraflagellar transport 140
IL1B interleukin 1, beta
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa
IPO9 importin 9
ITGB5 integrin, beta 5
KATNB1 katanin p80 (WD repeat containing) subunit B 1
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
KHDRBS2 KH domain containing, RNA binding, signal transduction associated 2
KIAA0125 KIAA0125
KIDINS220 kinase D-interacting substrate, 220kDa
KLHL22 kelch-like family member 22
LZTR1 leucine-zipper-like transcription regulator 1
LZTS3 leucine zipper, putative tumor suppressor family member 3
MAPK13 mitogen-activated protein kinase 13
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3
MCAM melanoma cell adhesion molecule
MFI2 antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5
MPP2 membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)
MSR1 macrophage scavenger receptor 1
NDRG2 NDRG family member 2
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NRP2 neuropilin 2
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa
OSMR oncostatin M receptor
PACS1 phosphofurin acidic cluster sorting protein 1
PDGFB platelet-derived growth factor beta polypeptide
PLAC4 placenta-specific 4
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PPP2R1B protein phosphatase 2, regulatory subunit A, beta
PRDM5 PR domain containing 5
PRDX2 peroxiredoxin 2
PRKCA protein kinase C, alpha
PRPH peripherin
PSMD11 proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
PVR poliovirus receptor
QKI QKI, KH domain containing, RNA binding
REM1 RAS (RAD and GEM)-like GTP-binding 1
RNASEH2B ribonuclease H2, subunit B
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae)
RTEL1 regulator of telomere elongation helicase 1
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SF3A2 splicing factor 3a, subunit 2, 66kDa
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SLC35A2 solute carrier family 35 (UDP-galactose transporter), member A2
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5
SLC8A1 solute carrier family 8 (sodium/calcium exchanger), member 1
SPAG8 sperm associated antigen 8
SPON1 spondin 1, extracellular matrix protein
SRI sorcin
SRRT serrate, RNA effector molecule
STIM1 stromal interaction molecule 1
STYK1 serine/threonine/tyrosine kinase 1
TAOK1 TAO kinase 1
TBC1D17 TBC1 domain family, member 17
TFF2 trefoil factor 2
THOC5 THO complex 5
TIMM8A translocase of inner mitochondrial membrane 8 homolog A (yeast)
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TPD52 tumor protein D52
UTRN utrophin
WDR62 WD repeat domain 62
WDR78 WD repeat domain 78
WNK1 WNK lysine deficient protein kinase 1
ZMYND8 zinc finger, MYND-type containing 8
ZNF235 zinc finger protein 235
ZNF37BP zinc finger protein 37B, pseudogene
ZNF440 zinc finger protein 440

decreased expression

Symbol Name
ALPK1 alpha-kinase 1
ARHGAP5 Rho GTPase activating protein 5
ARID4A AT rich interactive domain 4A (RBP1-like)
BCAR3 breast cancer anti-estrogen resistance 3
BTBD2 BTB (POZ) domain containing 2
C14ORF132 chromosome 14 open reading frame 132
C1ORF115 chromosome 1 open reading frame 115
CARD8 caspase recruitment domain family, member 8
CCDC88C coiled-coil domain containing 88C
CDK5RAP2 CDK5 regulatory subunit associated protein 2
CEP85 centrosomal protein 85kDa
CERK ceramide kinase
CHD8 chromodomain helicase DNA binding protein 8
CHST12 carbohydrate (chondroitin 4) sulfotransferase 12
CNGB3 cyclic nucleotide gated channel beta 3
CNN2 calponin 2
COPS7B COP9 signalosome subunit 7B
CRYL1 crystallin, lambda 1
CSAD cysteine sulfinic acid decarboxylase
CYP20A1 cytochrome P450, family 20, subfamily A, polypeptide 1
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DLEU2 deleted in lymphocytic leukemia 2 (non-protein coding)
DNAJB14 DnaJ (Hsp40) homolog, subfamily B, member 14
EAF2 ELL associated factor 2
EFNA1 ephrin-A1
EFNA4 ephrin-A4
FAM127B family with sequence similarity 127, member B
FBXW12 F-box and WD repeat domain containing 12
FCHO1 FCH domain only 1
GLI3 GLI family zinc finger 3
GOLGA8B golgin A8 family, member B
GPR87 G protein-coupled receptor 87
HAUS6 HAUS augmin-like complex, subunit 6
HCFC2 host cell factor C2
HIST1H1D histone cluster 1, H1d
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HMHA1 histocompatibility (minor) HA-1
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
INF2 inverted formin, FH2 and WH2 domain containing
INSIG2 insulin induced gene 2
JUNB jun B proto-oncogene
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KIFAP3 kinesin-associated protein 3
KLHL2 kelch-like family member 2
LHFPL2 lipoma HMGIC fusion partner-like 2
LIG1 ligase I, DNA, ATP-dependent
LYPD3 LY6/PLAUR domain containing 3
MAST3 microtubule associated serine/threonine kinase 3
MBIP MAP3K12 binding inhibitory protein 1
MFF mitochondrial fission factor
MLYCD malonyl-CoA decarboxylase
MT1H metallothionein 1H
NBEAL2 neurobeachin-like 2
NES nestin
NPM3 nucleophosmin/nucleoplasmin 3
NR1D2 nuclear receptor subfamily 1, group D, member 2
ORAI3 ORAI calcium release-activated calcium modulator 3
PACSIN3 protein kinase C and casein kinase substrate in neurons 3
PCDHB3 protocadherin beta 3
PCSK7 proprotein convertase subtilisin/kexin type 7
PEX26 peroxisomal biogenesis factor 26
PIGH phosphatidylinositol glycan anchor biosynthesis, class H
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
POR P450 (cytochrome) oxidoreductase
PRAF2 PRA1 domain family, member 2
PSTPIP2 proline-serine-threonine phosphatase interacting protein 2
PTBP2 polypyrimidine tract binding protein 2
PVRL2 poliovirus receptor-related 2 (herpesvirus entry mediator B)
RAB33B RAB33B, member RAS oncogene family
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RECQL4 RecQ protein-like 4
RNF31 ring finger protein 31
RPRM reprimo, TP53 dependent G2 arrest mediator candidate
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1
RWDD3 RWD domain containing 3
SCAMP4 secretory carrier membrane protein 4
SETD8 SET domain containing (lysine methyltransferase) 8
SF3A3 splicing factor 3a, subunit 3, 60kDa
SH2D4A SH2 domain containing 4A
SLC12A8 solute carrier family 12, member 8
SLC26A6 solute carrier family 26 (anion exchanger), member 6
SNX15 sorting nexin 15
SYNJ2BP synaptojanin 2 binding protein
TCEAL1 transcription elongation factor A (SII)-like 1
TMEM127 transmembrane protein 127
TMUB2 transmembrane and ubiquitin-like domain containing 2
TOPORS topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase
TPST2 tyrosylprotein sulfotransferase 2
TRAF2 TNF receptor-associated factor 2
TRIM52 tripartite motif containing 52
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TUBA3C tubulin, alpha 3c
TUBGCP5 tubulin, gamma complex associated protein 5
XAB2 XPA binding protein 2
ZNF219 zinc finger protein 219
ZNF430 zinc finger protein 430
ZNF552 zinc finger protein 552