natamycin-6126 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the natamycin-6126 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACAN aggrecan
ADGRB2 adhesion G protein-coupled receptor B2
AGFG2 ArfGAP with FG repeats 2
APOL1 apolipoprotein L, 1
APOL2 apolipoprotein L, 2
ARHGAP44 Rho GTPase activating protein 44
ARHGEF10 Rho guanine nucleotide exchange factor (GEF) 10
BCAR3 breast cancer anti-estrogen resistance 3
BRF1 BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
C1ORF61 chromosome 1 open reading frame 61
CAMKV CaM kinase-like vesicle-associated
CAV2 caveolin 2
CCK cholecystokinin
CCL22 chemokine (C-C motif) ligand 22
CDH8 cadherin 8, type 2
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CLTA clathrin, light chain A
COL7A1 collagen, type VII, alpha 1
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
DNAJC4 DnaJ (Hsp40) homolog, subfamily C, member 4
DOCK5 dedicator of cytokinesis 5
DRD5 dopamine receptor D5
DST dystonin
EFNA5 ephrin-A5
EIF1 eukaryotic translation initiation factor 1
ELAVL3 ELAV like neuron-specific RNA binding protein 3
EMILIN2 elastin microfibril interfacer 2
ETV7 ets variant 7
EXOSC2 exosome component 2
FAM135A family with sequence similarity 135, member A
FLT4 fms-related tyrosine kinase 4
FOXH1 forkhead box H1
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
GAST gastrin
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
GPC1 glypican 1
GRM7 glutamate receptor, metabotropic 7
GSK3A glycogen synthase kinase 3 alpha
HAP1 huntingtin-associated protein 1
HIST1H2AI histone cluster 1, H2ai
HLA-DOB major histocompatibility complex, class II, DO beta
IGLV3-19 immunoglobulin lambda variable 3-19
IQCA1 IQ motif containing with AAA domain 1
KRT85 keratin 85, type II
LAMB4 laminin, beta 4
LOX lysyl oxidase
MIR600HG MIR600 host gene
MTSS1 metastasis suppressor 1
MYRF myelin regulatory factor
NEBL nebulette
NFATC4 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
ONECUT1 one cut homeobox 1
OPTN optineurin
OR10J1 olfactory receptor, family 10, subfamily J, member 1
PAPOLG poly(A) polymerase gamma
PCGF2 polycomb group ring finger 2
PCSK6 proprotein convertase subtilisin/kexin type 6
PER3 period circadian clock 3
PFKFB1 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
POFUT1 protein O-fucosyltransferase 1
PSEN2 presenilin 2
PSG4 pregnancy specific beta-1-glycoprotein 4
RFX2 regulatory factor X, 2 (influences HLA class II expression)
RGS4 regulator of G-protein signaling 4
RIMS2 regulating synaptic membrane exocytosis 2
RNASE3 ribonuclease, RNase A family, 3
RTEL1 regulator of telomere elongation helicase 1
RYR1 ryanodine receptor 1 (skeletal)
SEZ6L seizure related 6 homolog (mouse)-like
SGCD sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
SH3BP1 SH3-domain binding protein 1
SIX2 SIX homeobox 2
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7
SLC22A18AS solute carrier family 22 (organic cation transporter), member 18 antisense
SLC39A9 solute carrier family 39, member 9
SLC6A13 solute carrier family 6 (neurotransmitter transporter), member 13
SLC6A2 solute carrier family 6 (neurotransmitter transporter), member 2
SLIT2 slit homolog 2 (Drosophila)
SOX4 SRY (sex determining region Y)-box 4
SP1 Sp1 transcription factor
SPDEF SAM pointed domain containing ETS transcription factor
SPHK2 sphingosine kinase 2
SPIB Spi-B transcription factor (Spi-1/PU.1 related)
SPTLC3 serine palmitoyltransferase, long chain base subunit 3
SRPK3 SRSF protein kinase 3
SYT2 synaptotagmin II
TRIM3 tripartite motif containing 3
TRIM49 tripartite motif containing 49
TRMT44 tRNA methyltransferase 44 homolog (S. cerevisiae)
TRPM3 transient receptor potential cation channel, subfamily M, member 3
USB1 U6 snRNA biogenesis 1
USP29 ubiquitin specific peptidase 29
WDR25 WD repeat domain 25
ZER1 zyg-11 related, cell cycle regulator
ZNF384 zinc finger protein 384
ZNF507 zinc finger protein 507

decreased expression

Symbol Name
AEN apoptosis enhancing nuclease
AMPD2 adenosine monophosphate deaminase 2
ANXA3 annexin A3
APBB1IP amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
APH1B APH1B gamma secretase subunit
APOBEC3B apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B
ARG1 arginase 1
ASGR2 asialoglycoprotein receptor 2
C19ORF40 chromosome 19 open reading frame 40
C9ORF9 chromosome 9 open reading frame 9
CAPRIN2 caprin family member 2
CD300C CD300c molecule
CD70 CD70 molecule
CLSPN claspin
COQ6 coenzyme Q6 monooxygenase
CRABP2 cellular retinoic acid binding protein 2
CRY2 cryptochrome circadian clock 2
CTSO cathepsin O
CXORF56 chromosome X open reading frame 56
CYBRD1 cytochrome b reductase 1
CYP2R1 cytochrome P450, family 2, subfamily R, polypeptide 1
CYSLTR1 cysteinyl leukotriene receptor 1
DCAF17 DDB1 and CUL4 associated factor 17
DEPDC5 DEP domain containing 5
DUSP5 dual specificity phosphatase 5
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1
ENO2 enolase 2 (gamma, neuronal)
EXOC2 exocyst complex component 2
FAM114A1 family with sequence similarity 114, member A1
FGGY FGGY carbohydrate kinase domain containing
FOXRED2 FAD-dependent oxidoreductase domain containing 2
GLCE glucuronic acid epimerase
GPATCH3 G patch domain containing 3
GPR22 G protein-coupled receptor 22
GSTCD glutathione S-transferase, C-terminal domain containing
HCAR3 hydroxycarboxylic acid receptor 3
HIST1H2BN histone cluster 1, H2bn
HP haptoglobin
IFT81 intraflagellar transport 81
IGFLR1 IGF-like family receptor 1
IKZF5 IKAROS family zinc finger 5 (Pegasus)
KBTBD4 kelch repeat and BTB (POZ) domain containing 4
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KIFC1 kinesin family member C1
LAIR2 leukocyte-associated immunoglobulin-like receptor 2
MLYCD malonyl-CoA decarboxylase
MOCS3 molybdenum cofactor synthesis 3
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
NCALD neurocalcin delta
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PARP16 poly (ADP-ribose) polymerase family, member 16
PGM3 phosphoglucomutase 3
PGP phosphoglycolate phosphatase
PHC1 polyhomeotic homolog 1 (Drosophila)
PID1 phosphotyrosine interaction domain containing 1
PIGH phosphatidylinositol glycan anchor biosynthesis, class H
PIGL phosphatidylinositol glycan anchor biosynthesis, class L
POLM polymerase (DNA directed), mu
PPM1H protein phosphatase, Mg2+/Mn2+ dependent, 1H
PRPF38B pre-mRNA processing factor 38B
PWAR5 Prader Willi/Angelman region RNA 5
RAB4B RAB4B, member RAS oncogene family
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RPL13P5 ribosomal protein L13 pseudogene 5
RPL23AP32 ribosomal protein L23a pseudogene 32
SEC22A SEC22 vesicle trafficking protein homolog A (S. cerevisiae)
SFXN1 sideroflexin 1
SIGLEC9 sialic acid binding Ig-like lectin 9
SLC2A9 solute carrier family 2 (facilitated glucose transporter), member 9
SLITRK5 SLIT and NTRK-like family, member 5
SNHG3 small nucleolar RNA host gene 3
SNRPC small nuclear ribonucleoprotein polypeptide C
SPIDR scaffolding protein involved in DNA repair
SPIN1 spindlin 1
SPON2 spondin 2, extracellular matrix protein
SPRYD7 SPRY domain containing 7
SSFA2 sperm specific antigen 2
STX17 syntaxin 17
THBS3 thrombospondin 3
THRAP3 thyroid hormone receptor associated protein 3
TIMP2 TIMP metallopeptidase inhibitor 2
TINF2 TERF1 (TRF1)-interacting nuclear factor 2
TMEM184B transmembrane protein 184B
TMEM209 transmembrane protein 209
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TUBA3C tubulin, alpha 3c
WASF3 WAS protein family, member 3
XPNPEP3 X-prolyl aminopeptidase 3, mitochondrial
ZBTB22 zinc finger and BTB domain containing 22
ZBTB38 zinc finger and BTB domain containing 38
ZFP37 ZFP37 zinc finger protein
ZFYVE16 zinc finger, FYVE domain containing 16
ZHX2 zinc fingers and homeoboxes 2
ZNF250 zinc finger protein 250
ZNF329 zinc finger protein 329
ZNF34 zinc finger protein 34
ZSCAN31 zinc finger and SCAN domain containing 31