natamycin-3548 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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198 genes differentially expressed following the natamycin-3548 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAK1 AP2 associated kinase 1
ADAP1 ArfGAP with dual PH domains 1
ANGPT4 angiopoietin 4
ANK1 ankyrin 1, erythrocytic
APOA1 apolipoprotein A-I
APOM apolipoprotein M
ASCL1 achaete-scute family bHLH transcription factor 1
ATP1A3 ATPase, Na+/K+ transporting, alpha 3 polypeptide
BMP15 bone morphogenetic protein 15
CALB2 calbindin 2
CARD14 caspase recruitment domain family, member 14
CASP2 caspase 2, apoptosis-related cysteine peptidase
CCPG1 cell cycle progression 1
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CHM choroideremia (Rab escort protein 1)
CHRNB3 cholinergic receptor, nicotinic, beta 3 (neuronal)
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2
CIZ1 CDKN1A interacting zinc finger protein 1
CLCN7 chloride channel, voltage-sensitive 7
CNGB1 cyclic nucleotide gated channel beta 1
CPQ carboxypeptidase Q
CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
CUL4B cullin 4B
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
CYP7B1 cytochrome P450, family 7, subfamily B, polypeptide 1
DBT dihydrolipoamide branched chain transacylase E2
DSC3 desmocollin 3
EFNA3 ephrin-A3
FAM149A family with sequence similarity 149, member A
FAM149B1 family with sequence similarity 149, member B1
FCAR Fc fragment of IgA receptor
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
FGF3 fibroblast growth factor 3
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GARNL3 GTPase activating Rap/RanGAP domain-like 3
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase)
GCNT4 glucosaminyl (N-acetyl) transferase 4, core 2
GLS glutaminase
GNAT2 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2
GPER1 G protein-coupled estrogen receptor 1
HDAC7 histone deacetylase 7
HIST1H2BO histone cluster 1, H2bo
HLA-DOA major histocompatibility complex, class II, DO alpha
HOXC5 homeobox C5
IBSP integrin-binding sialoprotein
ICOSLG inducible T-cell co-stimulator ligand
IFNW1 interferon, omega 1
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker)
IRAK3 interleukin-1 receptor-associated kinase 3
ITGB4 integrin, beta 4
KRT17 keratin 17, type I
KRT31 keratin 31, type I
LDLR low density lipoprotein receptor
LY6G6C lymphocyte antigen 6 complex, locus G6C
MORN1 MORN repeat containing 1
MTMR8 myotubularin related protein 8
MYOF myoferlin
NCKIPSD NCK interacting protein with SH3 domain
NF2 neurofibromin 2 (merlin)
NOX3 NADPH oxidase 3
NPC1 Niemann-Pick disease, type C1
ONECUT1 one cut homeobox 1
OXCT2 3-oxoacid CoA transferase 2
PCDHB17P protocadherin beta 17 pseudogene
PDHA2 pyruvate dehydrogenase (lipoamide) alpha 2
PRB1 proline-rich protein BstNI subfamily 1
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RERE arginine-glutamic acid dipeptide (RE) repeats
RGS12 regulator of G-protein signaling 12
RHOBTB2 Rho-related BTB domain containing 2
RND1 Rho family GTPase 1
ROBO3 roundabout, axon guidance receptor, homolog 3 (Drosophila)
S100A2 S100 calcium binding protein A2
S100A9 S100 calcium binding protein A9
SAMD9 sterile alpha motif domain containing 9
SATB2 SATB homeobox 2
SBNO1 strawberry notch homolog 1 (Drosophila)
SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
SEMA6D sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
SIX2 SIX homeobox 2
SLITRK5 SLIT and NTRK-like family, member 5
SOX5 SRY (sex determining region Y)-box 5
SP100 SP100 nuclear antigen
SPOCK3 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
SV2B synaptic vesicle glycoprotein 2B
TFEB transcription factor EB
TMEM8B transmembrane protein 8B
TMX4 thioredoxin-related transmembrane protein 4
TNS2 tensin 2
TRGV5 T cell receptor gamma variable 5
TSSK2 testis-specific serine kinase 2
UTP14A UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast)
UTS2 urotensin 2
VEZT vezatin, adherens junctions transmembrane protein
WSCD1 WSC domain containing 1
XYLB xylulokinase homolog (H. influenzae)
YIF1B Yip1 interacting factor homolog B (S. cerevisiae)
ZNF236 zinc finger protein 236
ZNF407 zinc finger protein 407

decreased expression

Symbol Name
ANKEF1 ankyrin repeat and EF-hand domain containing 1
ANKRD40 ankyrin repeat domain 40
ARHGEF10L Rho guanine nucleotide exchange factor (GEF) 10-like
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17
ARMC6 armadillo repeat containing 6
ARRB2 arrestin, beta 2
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
BAG4 BCL2-associated athanogene 4
BAHCC1 BAH domain and coiled-coil containing 1
BAHD1 bromo adjacent homology domain containing 1
BBC3 BCL2 binding component 3
BTBD2 BTB (POZ) domain containing 2
C14ORF93 chromosome 14 open reading frame 93
C16ORF45 chromosome 16 open reading frame 45
C1ORF105 chromosome 1 open reading frame 105
C1ORF159 chromosome 1 open reading frame 159
C7ORF43 chromosome 7 open reading frame 43
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CBX8 chromobox homolog 8
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CD82 CD82 molecule
CEP85 centrosomal protein 85kDa
CGA glycoprotein hormones, alpha polypeptide
CLIC3 chloride intracellular channel 3
CLUHP3 clustered mitochondria (cluA/CLU1) homolog pseudogene 3
CRLF1 cytokine receptor-like factor 1
CUEDC1 CUE domain containing 1
DBNDD1 dysbindin (dystrobrevin binding protein 1) domain containing 1
DEAF1 DEAF1 transcription factor
DNAL4 dynein, axonemal, light chain 4
DNMBP dynamin binding protein
EMD emerin
EPPK1 epiplakin 1
FAM86C1 family with sequence similarity 86, member C1
FBRS fibrosin
FBXO31 F-box protein 31
FOXN2 forkhead box N2
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GPR19 G protein-coupled receptor 19
HIST1H2AL histone cluster 1, H2al
HS1BP3 HCLS1 binding protein 3
HYI hydroxypyruvate isomerase (putative)
IL4R interleukin 4 receptor
KCTD7 potassium channel tetramerization domain containing 7
KIFC1 kinesin family member C1
KLHL25 kelch-like family member 25
LARP6 La ribonucleoprotein domain family, member 6
LHX1 LIM homeobox 1
LIN7A lin-7 homolog A (C. elegans)
LINC00339 long intergenic non-protein coding RNA 339
LRRC61 leucine rich repeat containing 61
MAGEF1 melanoma antigen family F1
MAP3K8 mitogen-activated protein kinase kinase kinase 8
MED15 mediator complex subunit 15
MEFV Mediterranean fever
MOCS3 molybdenum cofactor synthesis 3
MOGS mannosyl-oligosaccharide glucosidase
MT1F metallothionein 1F
MTERF4 mitochondrial transcription termination factor 4
MUL1 mitochondrial E3 ubiquitin protein ligase 1
NES nestin
NPM3 nucleophosmin/nucleoplasmin 3
NTHL1 nth endonuclease III-like 1 (E. coli)
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PADI1 peptidyl arginine deiminase, type I
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
PLXNA3 plexin A3
POM121 POM121 transmembrane nucleoporin
POPDC3 popeye domain containing 3
PRSS22 protease, serine, 22
RAB3A RAB3A, member RAS oncogene family
REEP4 receptor accessory protein 4
RPAP1 RNA polymerase II associated protein 1
RPH3AL rabphilin 3A-like (without C2 domains)
SCRN3 secernin 3
SERGEF secretion regulating guanine nucleotide exchange factor
SGCG sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)
SLC27A6 solute carrier family 27 (fatty acid transporter), member 6
STAP2 signal transducing adaptor family member 2
SULT4A1 sulfotransferase family 4A, member 1
SYCP2 synaptonemal complex protein 2
TFF3 trefoil factor 3 (intestinal)
TGFB1I1 transforming growth factor beta 1 induced transcript 1
THRAP3 thyroid hormone receptor associated protein 3
TMEM51 transmembrane protein 51
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
TOM1 target of myb1 (chicken)
TRIM66 tripartite motif containing 66
TRMU tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
TSSC4 tumor suppressing subtransferable candidate 4
TUBA3C tubulin, alpha 3c
ZNF10 zinc finger protein 10
ZNF350 zinc finger protein 350
ZNF606 zinc finger protein 606
ZNF747 zinc finger protein 747
ZNF787 zinc finger protein 787