nasolacrimal duct obstruction Gene Set

Dataset HPO Gene-Disease Associations
Category disease or phenotype associations
Type phenotype
Description any impediment or blockage of the paired channels leading from the lacrimal sacs to the inferior meatus of the nose, through which tears are conducted through the nasal cavity; may be either congenital or acquired; obstruction of the nasolacrimal duct leads to the excess overflow of tears called epiphora (Mammalian Phenotype Ontology, MP_0013451)
External Link http://compbio.charite.de/hpoweb/showterm?id=HP:0000579
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Genes

13 genes associated with the nasolacrimal duct obstruction phenotype by mapping known disease genes to disease phenotypes from the HPO Gene-Disease Associations dataset.

Symbol Name
CD151 CD151 molecule (Raph blood group)
CREBBP CREB binding protein
EYA1 EYA transcriptional coactivator and phosphatase 1
FGF10 fibroblast growth factor 10
FGFR2 fibroblast growth factor receptor 2
FGFR3 fibroblast growth factor receptor 3
FREM1 FRAS1 related extracellular matrix 1
NOP10 NOP10 ribonucleoprotein
PAX1 paired box 1
PTDSS1 phosphatidylserine synthase 1
TCOF1 Treacher Collins-Franceschetti syndrome 1
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TP63 tumor protein p63