naringin-3286 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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198 genes differentially expressed following the naringin-3286 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADORA1 adenosine A1 receptor
AFF2 AF4/FMR2 family, member 2
APBA2 amyloid beta (A4) precursor protein-binding, family A, member 2
ARG1 arginase 1
ARTN artemin
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
ATG10 autophagy related 10
AVPR1B arginine vasopressin receptor 1B
C14ORF132 chromosome 14 open reading frame 132
C17ORF53 chromosome 17 open reading frame 53
C1ORF54 chromosome 1 open reading frame 54
CASKIN2 CASK interacting protein 2
CEP170B centrosomal protein 170B
CNPPD1 cyclin Pas1/PHO80 domain containing 1
CNTN1 contactin 1
CSF1R colony stimulating factor 1 receptor
CTBP2 C-terminal binding protein 2
CYLD cylindromatosis (turban tumor syndrome)
CYP2C8 cytochrome P450, family 2, subfamily C, polypeptide 8
DGCR8 DGCR8 microprocessor complex subunit
DMXL2 Dmx-like 2
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DOCK6 dedicator of cytokinesis 6
DRD2 dopamine receptor D2
EGFL7 EGF-like-domain, multiple 7
EIF2S2 eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa
EML3 echinoderm microtubule associated protein like 3
EPOR erythropoietin receptor
ERMAP erythroblast membrane-associated protein (Scianna blood group)
EXO5 exonuclease 5
FAM46C family with sequence similarity 46, member C
GNL3L guanine nucleotide binding protein-like 3 (nucleolar)-like
GRAMD1C GRAM domain containing 1C
GRINA glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)
GRIP2 glutamate receptor interacting protein 2
GRM8 glutamate receptor, metabotropic 8
GYPB glycophorin B (MNS blood group)
HCFC1 host cell factor C1
HPS4 Hermansky-Pudlak syndrome 4
HR hair growth associated
IDUA iduronidase, alpha-L-
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker)
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
JAK2 Janus kinase 2
KIAA1107 KIAA1107
KLHL25 kelch-like family member 25
LILRA6 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
LZTR1 leucine-zipper-like transcription regulator 1
MAP2K5 mitogen-activated protein kinase kinase 5
MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2
MED18 mediator complex subunit 18
MKL1 megakaryoblastic leukemia (translocation) 1
NDRG4 NDRG family member 4
NFATC4 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
NGDN neuroguidin, EIF4E binding protein
OVGP1 oviductal glycoprotein 1, 120kDa
PARP3 poly (ADP-ribose) polymerase family, member 3
PICK1 protein interacting with PRKCA 1
PITX1 paired-like homeodomain 1
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PLTP phospholipid transfer protein
PODNL1 podocan-like 1
PPP2R3B protein phosphatase 2, regulatory subunit B'', beta
PRSS53 protease, serine, 53
R3HDM1 R3H domain containing 1
RAD54L2 RAD54-like 2 (S. cerevisiae)
RIMS2 regulating synaptic membrane exocytosis 2
RIMS3 regulating synaptic membrane exocytosis 3
RNF31 ring finger protein 31
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2
SAYSD1 SAYSVFN motif domain containing 1
SDC3 syndecan 3
SIPA1 signal-induced proliferation-associated 1
SLC24A1 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
SLC7A9 solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9
SLC9A5 solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5
SRD5A3 steroid 5 alpha-reductase 3
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced
STK17A serine/threonine kinase 17a
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TAF6L TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
THAP3 THAP domain containing, apoptosis associated protein 3
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TMC6 transmembrane channel-like 6
TNS1 tensin 1
TP53I11 tumor protein p53 inducible protein 11
TRAIP TRAF interacting protein
TRAK1 trafficking protein, kinesin binding 1
TSC22D4 TSC22 domain family, member 4
TYRO3 TYRO3 protein tyrosine kinase
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
ZFP36L2 ZFP36 ring finger protein-like 2
ZMIZ2 zinc finger, MIZ-type containing 2
ZNF609 zinc finger protein 609

decreased expression

Symbol Name
ABHD17B abhydrolase domain containing 17B
AGMAT agmatine ureohydrolase (agmatinase)
AMT aminomethyltransferase
ARMC4 armadillo repeat containing 4
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
ATHL1 ATH1, acid trehalase-like 1 (yeast)
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
C21ORF91 chromosome 21 open reading frame 91
C22ORF29 chromosome 22 open reading frame 29
C8ORF44 chromosome 8 open reading frame 44
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2
CAMK4 calcium/calmodulin-dependent protein kinase IV
CCDC176 coiled-coil domain containing 176
CEMIP cell migration inducing protein, hyaluronan binding
CENPO centromere protein O
CGREF1 cell growth regulator with EF-hand domain 1
CLCN5 chloride channel, voltage-sensitive 5
CNGB3 cyclic nucleotide gated channel beta 3
CYP2R1 cytochrome P450, family 2, subfamily R, polypeptide 1
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
DVL1 dishevelled segment polarity protein 1
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5
EPB41L5 erythrocyte membrane protein band 4.1 like 5
EXD3 exonuclease 3'-5' domain containing 3
FAM204A family with sequence similarity 204, member A
FER fer (fps/fes related) tyrosine kinase
FILIP1L filamin A interacting protein 1-like
FLCN folliculin
FRS2 fibroblast growth factor receptor substrate 2
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific)
GMPR guanosine monophosphate reductase
GPR176 G protein-coupled receptor 176
GSTA4 glutathione S-transferase alpha 4
GSTT1 glutathione S-transferase theta 1
HIST1H2AL histone cluster 1, H2al
HLA-DMA major histocompatibility complex, class II, DM alpha
IKZF5 IKAROS family zinc finger 5 (Pegasus)
INCENP inner centromere protein antigens 135/155kDa
LAMP3 lysosomal-associated membrane protein 3
LIME1 Lck interacting transmembrane adaptor 1
LINC00339 long intergenic non-protein coding RNA 339
LMNB1 lamin B1
LRRC6 leucine rich repeat containing 6
LTC4S leukotriene C4 synthase
MAP3K8 mitogen-activated protein kinase kinase kinase 8
MBNL3 muscleblind-like splicing regulator 3
MINOS1P1 mitochondrial inner membrane organizing system 1 pseudogene 1
MMP2 matrix metallopeptidase 2
MSI1 musashi RNA-binding protein 1
NEK11 NIMA-related kinase 11
NPFFR1 neuropeptide FF receptor 1
NUPL2 nucleoporin like 2
OCLM oculomedin
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
PDIA3 protein disulfide isomerase family A, member 3
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PGBD5 piggyBac transposable element derived 5
PHEX phosphate regulating endopeptidase homolog, X-linked
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PRR4 proline rich 4 (lacrimal)
PTK6 protein tyrosine kinase 6
QPCTL glutaminyl-peptide cyclotransferase-like
RSPH14 radial spoke head 14 homolog (Chlamydomonas)
RUSC2 RUN and SH3 domain containing 2
SCML2 sex comb on midleg-like 2 (Drosophila)
SGCG sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SLN sarcolipin
SLPI secretory leukocyte peptidase inhibitor
SP1 Sp1 transcription factor
SPATA2L spermatogenesis associated 2-like
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TBX19 T-box 19
TFF2 trefoil factor 2
TLN1 talin 1
TMEM209 transmembrane protein 209
TMEM242 transmembrane protein 242
TMEM254 transmembrane protein 254
TMEM45A transmembrane protein 45A
TOLLIP toll interacting protein
TRAF3IP1 TNF receptor-associated factor 3 interacting protein 1
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TRPV6 transient receptor potential cation channel, subfamily V, member 6
TSPAN1 tetraspanin 1
WDR91 WD repeat domain 91
WWC2 WW and C2 domain containing 2
ZBTB6 zinc finger and BTB domain containing 6
ZNF124 zinc finger protein 124
ZNF134 zinc finger protein 134
ZNF606 zinc finger protein 606
ZNF652 zinc finger protein 652
ZNF816 zinc finger protein 816
ZSCAN31 zinc finger and SCAN domain containing 31