naftifine-7273 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the naftifine-7273 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ANP32A acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
APOC1 apolipoprotein C-I
APP amyloid beta (A4) precursor protein
ATP9A ATPase, class II, type 9A
BBS7 Bardet-Biedl syndrome 7
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein)
BIRC3 baculoviral IAP repeat containing 3
BRD4 bromodomain containing 4
BTN3A1 butyrophilin, subfamily 3, member A1
CCDC6 coiled-coil domain containing 6
CCDC85C coiled-coil domain containing 85C
CDKL3 cyclin-dependent kinase-like 3
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CLCN4 chloride channel, voltage-sensitive 4
CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1
COL3A1 collagen, type III, alpha 1
CTGF connective tissue growth factor
CXCL3 chemokine (C-X-C motif) ligand 3
CYR61 cysteine-rich, angiogenic inducer, 61
DIP2A DIP2 disco-interacting protein 2 homolog A (Drosophila)
F3 coagulation factor III (thromboplastin, tissue factor)
FAM69A family with sequence similarity 69, member A
FGF2 fibroblast growth factor 2 (basic)
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GADD45B growth arrest and DNA-damage-inducible, beta
GK glycerol kinase
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis)
GPATCH2L G patch domain containing 2-like
GTPBP4 GTP binding protein 4
HDAC9 histone deacetylase 9
HDGFRP3 hepatoma-derived growth factor, related protein 3
HRH1 histamine receptor H1
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IKZF5 IKAROS family zinc finger 5 (Pegasus)
IPO8 importin 8
IRF1 interferon regulatory factor 1
ITSN1 intersectin 1 (SH3 domain protein)
KIAA1109 KIAA1109
KIDINS220 kinase D-interacting substrate, 220kDa
KLF13 Kruppel-like factor 13
KRIT1 KRIT1, ankyrin repeat containing
LMNB1 lamin B1
MDFI MyoD family inhibitor
MTAP methylthioadenosine phosphorylase
MTUS1 microtubule associated tumor suppressor 1
NAV3 neuron navigator 3
NEK9 NIMA-related kinase 9
NOTCH1 notch 1
NRP1 neuropilin 1
NRXN3 neurexin 3
NUPR1 nuclear protein, transcriptional regulator, 1
OASL 2'-5'-oligoadenylate synthetase-like
OPRL1 opiate receptor-like 1
PAFAH2 platelet-activating factor acetylhydrolase 2, 40kDa
PANK3 pantothenate kinase 3
PEX7 peroxisomal biogenesis factor 7
PHTF2 putative homeodomain transcription factor 2
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
PMEL premelanosome protein
POLR3C polymerase (RNA) III (DNA directed) polypeptide C (62kD)
PPFIA1 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1
PTPN18 protein tyrosine phosphatase, non-receptor type 18 (brain-derived)
QKI QKI, KH domain containing, RNA binding
RAB28 RAB28, member RAS oncogene family
RNASEH2B ribonuclease H2, subunit B
RNF19B ring finger protein 19B
RNF41 ring finger protein 41, E3 ubiquitin protein ligase
RUNDC3B RUN domain containing 3B
RUSC2 RUN and SH3 domain containing 2
SCARB1 scavenger receptor class B, member 1
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SERTAD3 SERTA domain containing 3
SKIL SKI-like proto-oncogene
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SLC43A1 solute carrier family 43 (amino acid system L transporter), member 1
SMC1A structural maintenance of chromosomes 1A
SMEK1 SMEK homolog 1, suppressor of mek1 (Dictyostelium)
SNAPC5 small nuclear RNA activating complex, polypeptide 5, 19kDa
SPATA5L1 spermatogenesis associated 5-like 1
SPSB3 splA/ryanodine receptor domain and SOCS box containing 3
SPTLC1 serine palmitoyltransferase, long chain base subunit 1
STK16 serine/threonine kinase 16
STX6 syntaxin 6
SYDE1 synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
TK2 thymidine kinase 2, mitochondrial
TNK1 tyrosine kinase, non-receptor, 1
TRIB3 tribbles pseudokinase 3
UTRN utrophin
VEGFA vascular endothelial growth factor A
VNN1 vanin 1
VWA8 von Willebrand factor A domain containing 8
WDFY3 WD repeat and FYVE domain containing 3
WHSC1L1 Wolf-Hirschhorn syndrome candidate 1-like 1
WWC1 WW and C2 domain containing 1
ZC3H7B zinc finger CCCH-type containing 7B
ZNF165 zinc finger protein 165
ZNF609 zinc finger protein 609

decreased expression

Symbol Name
ABHD8 abhydrolase domain containing 8
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
ALKBH4 alkB, alkylation repair homolog 4 (E. coli)
ANAPC2 anaphase promoting complex subunit 2
AP3M2 adaptor-related protein complex 3, mu 2 subunit
ARMC6 armadillo repeat containing 6
ATAD2 ATPase family, AAA domain containing 2
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1
AUH AU RNA binding protein/enoyl-CoA hydratase
AXIN1 axin 1
BHLHB9 basic helix-loop-helix domain containing, class B, 9
C8ORF60 chromosome 8 open reading frame 60
C9ORF114 chromosome 9 open reading frame 114
CALCOCO1 calcium binding and coiled-coil domain 1
CAPN15 calpain 15
CARD8 caspase recruitment domain family, member 8
CARM1 coactivator-associated arginine methyltransferase 1
CBX7 chromobox homolog 7
CCDC176 coiled-coil domain containing 176
CCNO cyclin O
CEMIP cell migration inducing protein, hyaluronan binding
CHKB choline kinase beta
CLDN15 claudin 15
CLSPN claspin
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
CYP26B1 cytochrome P450, family 26, subfamily B, polypeptide 1
DBF4B DBF4 zinc finger B
DDB2 damage-specific DNA binding protein 2, 48kDa
DHRS11 dehydrogenase/reductase (SDR family) member 11
ECI1 enoyl-CoA delta isomerase 1
EHD3 EH-domain containing 3
FAM206A family with sequence similarity 206, member A
FAM53B family with sequence similarity 53, member B
FARP2 FERM, RhoGEF and pleckstrin domain protein 2
FBXO2 F-box protein 2
FOXJ2 forkhead box J2
GAMT guanidinoacetate N-methyltransferase
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GRAMD4 GRAM domain containing 4
HLX H2.0-like homeobox
HOXC8 homeobox C8
HSPA2 heat shock 70kDa protein 2
IER3IP1 immediate early response 3 interacting protein 1
IFI30 interferon, gamma-inducible protein 30
IREB2 iron-responsive element binding protein 2
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
KIAA0513 KIAA0513
KIAA1551 KIAA1551
KLHL3 kelch-like family member 3
KLHL36 kelch-like family member 36
LPAR6 lysophosphatidic acid receptor 6
LRRC37A3 leucine rich repeat containing 37, member A3
LRRC49 leucine rich repeat containing 49
LYPLA2P1 lysophospholipase II pseudogene 1
LZTR1 leucine-zipper-like transcription regulator 1
METTL1 methyltransferase like 1
MFGE8 milk fat globule-EGF factor 8 protein
MFSD11 major facilitator superfamily domain containing 11
MMP1 matrix metallopeptidase 1
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
NBEAL2 neurobeachin-like 2
NDE1 nudE neurodevelopment protein 1
NSD1 nuclear receptor binding SET domain protein 1
ORC1 origin recognition complex, subunit 1
PARD6A par-6 family cell polarity regulator alpha
PIEZO1 piezo-type mechanosensitive ion channel component 1
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha
PTDSS2 phosphatidylserine synthase 2
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1
SALL2 spalt-like transcription factor 2
SCARA3 scavenger receptor class A, member 3
SELENBP1 selenium binding protein 1
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SLC14A1 solute carrier family 14 (urea transporter), member 1 (Kidd blood group)
SLC29A2 solute carrier family 29 (equilibrative nucleoside transporter), member 2
SMCO4 single-pass membrane protein with coiled-coil domains 4
SNTA1 syntrophin, alpha 1
SPEG SPEG complex locus
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TAF13 TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa
TMEM104 transmembrane protein 104
TMEM132A transmembrane protein 132A
TRAPPC12 trafficking protein particle complex 12
USB1 U6 snRNA biogenesis 1
USP27X ubiquitin specific peptidase 27, X-linked
WDR18 WD repeat domain 18
ZBED1 zinc finger, BED-type containing 1
ZBTB39 zinc finger and BTB domain containing 39
ZDHHC7 zinc finger, DHHC-type containing 7
ZNF222 zinc finger protein 222
ZNF230 zinc finger protein 230
ZNF574 zinc finger protein 574
ZNF862 zinc finger protein 862
ZRSR2 zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 2