naftifine-3536 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the naftifine-3536 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAM22 ADAM metallopeptidase domain 22
ADCK2 aarF domain containing kinase 2
ADGRF5 adhesion G protein-coupled receptor F5
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
ARHGAP35 Rho GTPase activating protein 35
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
ARNTL aryl hydrocarbon receptor nuclear translocator-like
ASNS asparagine synthetase (glutamine-hydrolyzing)
ATF3 activating transcription factor 3
BBS9 Bardet-Biedl syndrome 9
BLNK B-cell linker
BMP6 bone morphogenetic protein 6
CAPN9 calpain 9
CCNG2 cyclin G2
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CLGN calmegin
CR2 complement component (3d/Epstein Barr virus) receptor 2
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
DNAH17 dynein, axonemal, heavy chain 17
DSCAM Down syndrome cell adhesion molecule
DTNA dystrobrevin, alpha
DUSP10 dual specificity phosphatase 10
DYSF dysferlin
EML2 echinoderm microtubule associated protein like 2
ETV5 ets variant 5
EXOG endo/exonuclease (5'-3'), endonuclease G-like
FGD1 FYVE, RhoGEF and PH domain containing 1
FGD6 FYVE, RhoGEF and PH domain containing 6
FGF18 fibroblast growth factor 18
FMOD fibromodulin
GADD45A growth arrest and DNA-damage-inducible, alpha
GK3P glycerol kinase 3 pseudogene
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GOSR2 golgi SNAP receptor complex member 2
GRB10 growth factor receptor-bound protein 10
GRB7 growth factor receptor-bound protein 7
H6PD hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
HIST1H2BO histone cluster 1, H2bo
HMOX1 heme oxygenase 1
ICAM1 intercellular adhesion molecule 1
IDUA iduronidase, alpha-L-
INHBE inhibin, beta E
KANSL3 KAT8 regulatory NSL complex subunit 3
KLHL24 kelch-like family member 24
LILRA1 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1
LINC00341 long intergenic non-protein coding RNA 341
LOC729164 hCG1732469
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAK male germ cell-associated kinase
MARS methionyl-tRNA synthetase
MECOM MDS1 and EVI1 complex locus
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
MPZ myelin protein zero
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NFIL3 nuclear factor, interleukin 3 regulated
NMT2 N-myristoyltransferase 2
NOP16 NOP16 nucleolar protein
NUPR1 nuclear protein, transcriptional regulator, 1
OASL 2'-5'-oligoadenylate synthetase-like
PAWR PRKC, apoptosis, WT1, regulator
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial)
PER1 period circadian clock 1
PEX16 peroxisomal biogenesis factor 16
PHKG1 phosphorylase kinase, gamma 1 (muscle)
PKD1 polycystic kidney disease 1 (autosomal dominant)
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PPP1R15A protein phosphatase 1, regulatory subunit 15A
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
PRR4 proline rich 4 (lacrimal)
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RPS3A ribosomal protein S3A
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2
SH3TC1 SH3 domain and tetratricopeptide repeats 1
SLC48A1 solute carrier family 48 (heme transporter), member 1
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
SNX13 sorting nexin 13
SPRY4 sprouty homolog 4 (Drosophila)
TES testin LIM domain protein
THBS3 thrombospondin 3
TMEM206 transmembrane protein 206
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TRD T cell receptor delta locus
TRDMT1 tRNA aspartic acid methyltransferase 1
TTLL4 tubulin tyrosine ligase-like family member 4
UGT8 UDP glycosyltransferase 8
VEGFA vascular endothelial growth factor A
VLDLR very low density lipoprotein receptor
ZFP64 ZFP64 zinc finger protein
ZFX zinc finger protein, X-linked
ZNF3 zinc finger protein 3
ZNF419 zinc finger protein 419
ZNF76 zinc finger protein 76

decreased expression

Symbol Name
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6
ABHD17B abhydrolase domain containing 17B
ACAD10 acyl-CoA dehydrogenase family, member 10
ADM adrenomedullin
AKAP12 A kinase (PRKA) anchor protein 12
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
BCL9 B-cell CLL/lymphoma 9
BEGAIN brain-enriched guanylate kinase-associated
C11ORF80 chromosome 11 open reading frame 80
C22ORF29 chromosome 22 open reading frame 29
C5AR2 complement component 5a receptor 2
CALCOCO1 calcium binding and coiled-coil domain 1
CAPN5 calpain 5
CCDC121 coiled-coil domain containing 121
CCDC85C coiled-coil domain containing 85C
CCNO cyclin O
CHMP6 charged multivesicular body protein 6
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
CST6 cystatin E/M
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DAGLA diacylglycerol lipase, alpha
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
EFNA3 ephrin-A3
FAM46C family with sequence similarity 46, member C
FDXR ferredoxin reductase
FER fer (fps/fes related) tyrosine kinase
FLNC filamin C, gamma
FOXN2 forkhead box N2
FSTL3 follistatin-like 3 (secreted glycoprotein)
GNAT2 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2
HIST1H2AJ histone cluster 1, H2aj
HIST1H2AK histone cluster 1, H2ak
HOXC10 homeobox C10
HOXC5 homeobox C5
KBTBD11 kelch repeat and BTB (POZ) domain containing 11
KLF2 Kruppel-like factor 2
KLK5 kallikrein-related peptidase 5
LAMB1 laminin, beta 1
LAX1 lymphocyte transmembrane adaptor 1
LCP1 lymphocyte cytosolic protein 1 (L-plastin)
LIN7A lin-7 homolog A (C. elegans)
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
MAGEA6 melanoma antigen family A6
MAST3 microtubule associated serine/threonine kinase 3
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MUL1 mitochondrial E3 ubiquitin protein ligase 1
MUM1 melanoma associated antigen (mutated) 1
MVD mevalonate (diphospho) decarboxylase
NCALD neurocalcin delta
NNAT neuronatin
NPM3 nucleophosmin/nucleoplasmin 3
NUP62CL nucleoporin 62kDa C-terminal like
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PALM paralemmin
PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PLA2G3 phospholipase A2, group III
POM121 POM121 transmembrane nucleoporin
PRODH proline dehydrogenase (oxidase) 1
PRR14L proline rich 14-like
RAD54L RAD54-like (S. cerevisiae)
RASL11B RAS-like, family 11, member B
ROBO3 roundabout, axon guidance receptor, homolog 3 (Drosophila)
RUSC2 RUN and SH3 domain containing 2
SCAI suppressor of cancer cell invasion
SCARA3 scavenger receptor class A, member 3
SECTM1 secreted and transmembrane 1
SEMA6D sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SH2B3 SH2B adaptor protein 3
SHPK sedoheptulokinase
SLC41A3 solute carrier family 41, member 3
SPANXC SPANX family, member C
STARD5 StAR-related lipid transfer (START) domain containing 5
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TMEM121 transmembrane protein 121
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TOPORS topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase
TSGA10 testis specific, 10
TSPAN5 tetraspanin 5
TTLL1 tubulin tyrosine ligase-like family member 1
UPK3B uroplakin 3B
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
VEGFC vascular endothelial growth factor C
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
ZC3H3 zinc finger CCCH-type containing 3
ZNF34 zinc finger protein 34
ZNF574 zinc finger protein 574
ZNF639 zinc finger protein 639
ZNF701 zinc finger protein 701