nadph oxidase complex Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A enzyme complex of which the core is a heterodimer composed of a light (alpha) and heavy (beta) chain, and requires several other water-soluble proteins of cytosolic origin for activity. Functions in superoxide generation by the NADPH-dependent reduction of O2. (Gene Ontology, GO_0043020)
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85 proteins co-occuring with the nadph oxidase complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial 3.04714
NOX1 NADPH oxidase 1 2.81429
NOX4 NADPH oxidase 4 2.66825
CYBA cytochrome b-245, alpha polypeptide 2.38287
NOX5 NADPH oxidase, EF-hand calcium binding domain 5 2.24589
CYBB cytochrome b-245, beta polypeptide 1.93065
NOX3 NADPH oxidase 3 1.90355
DUOX1 dual oxidase 1 1.74003
NOXO1 NADPH oxidase organizer 1 1.62945
NOXA1 NADPH oxidase activator 1 1.60651
NCF1 neutrophil cytosolic factor 1 1.58968
DUOX2 dual oxidase 2 1.57645
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 1.56446
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) 1.55254
NCF1C neutrophil cytosolic factor 1C pseudogene 1.49267
NCF2 neutrophil cytosolic factor 2 1.4904
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) 1.44968
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.27717
DUOXA2 dual oxidase maturation factor 2 1.13471
DUOXA1 dual oxidase maturation factor 1 1.06549
SOD2 superoxide dismutase 2, mitochondrial 1.02231
NCF4 neutrophil cytosolic factor 4, 40kDa 0.993183
NOS3 nitric oxide synthase 3 (endothelial cell) 0.990736
CAT catalase 0.850665
PXDN peroxidasin 0.760433
HOXA10 homeobox A10 0.676368
RAP1A RAP1A, member of RAS oncogene family 0.599802
KIAA0226 KIAA0226 0.491752
TRPM3 transient receptor potential cation channel, subfamily M, member 3 0.489327
TXN thioredoxin 0.472412
MPO myeloperoxidase 0.456809
MAPK3 mitogen-activated protein kinase 3 0.444085
GPX1 glutathione peroxidase 1 0.408309
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha 0.404026
ACE angiotensin I converting enzyme 0.362422
SAR1A secretion associated, Ras related GTPase 1A 0.347967
HACE1 HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1 0.33511
IRF8 interferon regulatory factor 8 0.334733
RAP2B RAP2B, member of RAS oncogene family 0.329461
ARF3 ADP-ribosylation factor 3 0.322325
CARD9 caspase recruitment domain family, member 9 0.320451
RAB1B RAB1B, member RAS oncogene family 0.319702
TNF tumor necrosis factor 0.318953
GPX5 glutathione peroxidase 5 0.302168
ARHGAP25 Rho GTPase activating protein 25 0.298084
GPX4 glutathione peroxidase 4 0.296601
SRC SRC proto-oncogene, non-receptor tyrosine kinase 0.294007
FSD1 fibronectin type III and SPRY domain containing 1 0.283663
IL1B interleukin 1, beta 0.275936
CDC42 cell division cycle 42 0.274468
KIAA1919 KIAA1919 0.269701
DHRS2 dehydrogenase/reductase (SDR family) member 2 0.266408
P4HB prolyl 4-hydroxylase, beta polypeptide 0.260566
PTPN11 protein tyrosine phosphatase, non-receptor type 11 0.253653
PPP3R2 protein phosphatase 3, regulatory subunit B, beta 0.243158
YME1L1 YME1-like 1 ATPase 0.242076
SNRK SNF related kinase 0.22279
XCR1 chemokine (C motif) receptor 1 0.204718
PAOX polyamine oxidase (exo-N4-amino) 0.203022
APOE apolipoprotein E 0.196339
PSPH phosphoserine phosphatase 0.19601
RFC2 replication factor C (activator 1) 2, 40kDa 0.195681
WAPAL wings apart-like homolog (Drosophila) 0.195025
PTPRD protein tyrosine phosphatase, receptor type, D 0.1921
GPX3 glutathione peroxidase 3 0.191456
PBX1 pre-B-cell leukemia homeobox 1 0.184241
PTPN12 protein tyrosine phosphatase, non-receptor type 12 0.183935
AGTR1 angiotensin II receptor, type 1 0.182122
GPX7 glutathione peroxidase 7 0.181823
GCH1 GTP cyclohydrolase 1 0.180634
TXN2 thioredoxin 2 0.179459
JUN jun proto-oncogene 0.175188
TGFB1 transforming growth factor, beta 1 0.170629
SIRT1 sirtuin 1 0.170371
SMAD3 SMAD family member 3 0.168349
STEAP1 six transmembrane epithelial antigen of the prostate 1 0.166167
UTS2 urotensin 2 0.165
CLCN3 chloride channel, voltage-sensitive 3 0.161693
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64) 0.160658
TLR4 toll-like receptor 4 0.159658
GATA6 GATA binding protein 6 0.158129
GSR glutathione reductase 0.15776
RCHY1 ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase 0.15776
CCL2 chemokine (C-C motif) ligand 2 0.156863
PPARG peroxisome proliferator-activated receptor gamma 0.156688