nadide-6091 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the nadide-6091 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACAA2 acetyl-CoA acyltransferase 2
AJAP1 adherens junctions associated protein 1
ALOX5AP arachidonate 5-lipoxygenase-activating protein
ANGPTL2 angiopoietin-like 2
ANKRD7 ankyrin repeat domain 7
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
ATP11A ATPase, class VI, type 11A
ATP9B ATPase, class II, type 9B
ATXN2L ataxin 2-like
BAIAP3 BAI1-associated protein 3
BCL2 B-cell CLL/lymphoma 2
BTN2A3P butyrophilin, subfamily 2, member A3, pseudogene
BTN3A1 butyrophilin, subfamily 3, member A1
C1QTNF1 C1q and tumor necrosis factor related protein 1
C4BPA complement component 4 binding protein, alpha
C8B complement component 8, beta polypeptide
CAMSAP1 calmodulin regulated spectrin-associated protein 1
CFHR2 complement factor H-related 2
CLSTN3 calsyntenin 3
CRHR2 corticotropin releasing hormone receptor 2
CXCR4 chemokine (C-X-C motif) receptor 4
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1)
DGCR8 DGCR8 microprocessor complex subunit
DOCK5 dedicator of cytokinesis 5
EDA ectodysplasin A
ELOVL5 ELOVL fatty acid elongase 5
ETV6 ets variant 6
FEZ2 fasciculation and elongation protein zeta 2 (zygin II)
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12
GBA3 glucosidase, beta, acid 3 (gene/pseudogene)
GLB1L galactosidase, beta 1-like
GPR176 G protein-coupled receptor 176
GSAP gamma-secretase activating protein
HES2 hes family bHLH transcription factor 2
HIST1H1E histone cluster 1, H1e
HLA-DOA major histocompatibility complex, class II, DO alpha
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HYMAI hydatidiform mole associated and imprinted (non-protein coding)
ICOSLG inducible T-cell co-stimulator ligand
ITGA7 integrin, alpha 7
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KCNE2 potassium channel, voltage gated subfamily E regulatory beta subunit 2
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
LAMP1 lysosomal-associated membrane protein 1
LAT2 linker for activation of T cells family, member 2
LCAT lecithin-cholesterol acyltransferase
LDLRAD4 low density lipoprotein receptor class A domain containing 4
LRRC23 leucine rich repeat containing 23
MAP4K1 mitogen-activated protein kinase kinase kinase kinase 1
MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2
MAPK8 mitogen-activated protein kinase 8
MAS1 MAS1 proto-oncogene, G protein-coupled receptor
MED25 mediator complex subunit 25
METTL7A methyltransferase like 7A
MIER2 mesoderm induction early response 1, family member 2
MLN motilin
MRPL41 mitochondrial ribosomal protein L41
N4BP2L1 NEDD4 binding protein 2-like 1
NF2 neurofibromin 2 (merlin)
NR6A1 nuclear receptor subfamily 6, group A, member 1
NSUN6 NOP2/Sun domain family, member 6
NTN1 netrin 1
OR2C1 olfactory receptor, family 2, subfamily C, member 1
PAX8 paired box 8
PBOV1 prostate and breast cancer overexpressed 1
PDE10A phosphodiesterase 10A
PDPN podoplanin
PRKCI protein kinase C, iota
PRUNE2 prune homolog 2 (Drosophila)
PTPN1 protein tyrosine phosphatase, non-receptor type 1
PTPN11 protein tyrosine phosphatase, non-receptor type 11
RAB3B RAB3B, member RAS oncogene family
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
RGS14 regulator of G-protein signaling 14
SALL1 spalt-like transcription factor 1
SEC14L4 SEC14-like 4 (S. cerevisiae)
SEMA7A semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)
SFI1 Sfi1 homolog, spindle assembly associated (yeast)
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
SLC16A5 solute carrier family 16 (monocarboxylate transporter), member 5
SLC22A7 solute carrier family 22 (organic anion transporter), member 7
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2
SLCO2B1 solute carrier organic anion transporter family, member 2B1
SPINK5 serine peptidase inhibitor, Kazal type 5
SPTAN1 spectrin, alpha, non-erythrocytic 1
SPTBN4 spectrin, beta, non-erythrocytic 4
SRF serum response factor (c-fos serum response element-binding transcription factor)
SYNGR1 synaptogyrin 1
TBL2 transducin (beta)-like 2
TEX14 testis expressed 14
TGM2 transglutaminase 2
THAP3 THAP domain containing, apoptosis associated protein 3
TIMP3 TIMP metallopeptidase inhibitor 3
TMBIM1 transmembrane BAX inhibitor motif containing 1
TRAT1 T cell receptor associated transmembrane adaptor 1
ZBTB7A zinc finger and BTB domain containing 7A
ZNF589 zinc finger protein 589

decreased expression

Symbol Name
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
ADAM23 ADAM metallopeptidase domain 23
ANP32A-IT1 ANP32A intronic transcript 1
BFSP1 beaded filament structural protein 1, filensin
C7ORF43 chromosome 7 open reading frame 43
CCDC9 coiled-coil domain containing 9
CCP110 centriolar coiled coil protein 110kDa
CD82 CD82 molecule
CHKB choline kinase beta
CNTN1 contactin 1
CSF1R colony stimulating factor 1 receptor
CYP2B7P cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene
DNAH17 dynein, axonemal, heavy chain 17
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DYSF dysferlin
ERCC6 excision repair cross-complementation group 6
ETNK2 ethanolamine kinase 2
FCHO1 FCH domain only 1
FGL1 fibrinogen-like 1
FILIP1L filamin A interacting protein 1-like
FLCN folliculin
FOXN2 forkhead box N2
FPGS folylpolyglutamate synthase
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GEM GTP binding protein overexpressed in skeletal muscle
GLI3 GLI family zinc finger 3
GNG3 guanine nucleotide binding protein (G protein), gamma 3
GPRIN2 G protein regulated inducer of neurite outgrowth 2
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
HNRNPA3P1 heterogeneous nuclear ribonucleoprotein A3 pseudogene 1
HOXB2 homeobox B2
HSPB6 heat shock protein, alpha-crystallin-related, B6
IFNA14 interferon, alpha 14
IFT140 intraflagellar transport 140
IL22 interleukin 22
INPP1 inositol polyphosphate-1-phosphatase
IQCC IQ motif containing C
IRF2BP1 interferon regulatory factor 2 binding protein 1
KBTBD11 kelch repeat and BTB (POZ) domain containing 11
KCTD7 potassium channel tetramerization domain containing 7
KIAA0125 KIAA0125
LIN7A lin-7 homolog A (C. elegans)
LOC729164 hCG1732469
LOC730101 uncharacterized LOC730101
LRRC8E leucine rich repeat containing 8 family, member E
LY6G6C lymphocyte antigen 6 complex, locus G6C
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1
MAP3K8 mitogen-activated protein kinase kinase kinase 8
MAST3 microtubule associated serine/threonine kinase 3
MRPL44 mitochondrial ribosomal protein L44
MVP major vault protein
MXD3 MAX dimerization protein 3
MYL5 myosin, light chain 5, regulatory
MYLK myosin light chain kinase
NOL10 nucleolar protein 10
NRSN2 neurensin 2
NT5E 5'-nucleotidase, ecto (CD73)
OLFML2A olfactomedin-like 2A
OVOL1 ovo-like zinc finger 1
PCDHA5 protocadherin alpha 5
PHOX2A paired-like homeobox 2a
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
PLA2G3 phospholipase A2, group III
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
PRODH proline dehydrogenase (oxidase) 1
PTPN14 protein tyrosine phosphatase, non-receptor type 14
RPL23AP32 ribosomal protein L23a pseudogene 32
RWDD3 RWD domain containing 3
SCML2 sex comb on midleg-like 2 (Drosophila)
SLC17A2 solute carrier family 17, member 2
SLC44A1 solute carrier family 44 (choline transporter), member 1
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TFF2 trefoil factor 2
TICAM1 toll-like receptor adaptor molecule 1
TMCC2 transmembrane and coiled-coil domain family 2
TMEM104 transmembrane protein 104
TMEM242 transmembrane protein 242
TNRC6B trinucleotide repeat containing 6B
TRAF2 TNF receptor-associated factor 2
TRPM4 transient receptor potential cation channel, subfamily M, member 4
TRPV6 transient receptor potential cation channel, subfamily V, member 6
TSC22D4 TSC22 domain family, member 4
UBXN6 UBX domain protein 6
UGGT2 UDP-glucose glycoprotein glucosyltransferase 2
UPK3B uroplakin 3B
VAX2 ventral anterior homeobox 2
VEGFB vascular endothelial growth factor B
VEZT vezatin, adherens junctions transmembrane protein
WNT10B wingless-type MMTV integration site family, member 10B
ZBTB39 zinc finger and BTB domain containing 39
ZNF12 zinc finger protein 12
ZNF16 zinc finger protein 16
ZNF324 zinc finger protein 324
ZNF350 zinc finger protein 350
ZNF551 zinc finger protein 551
ZNF747 zinc finger protein 747
ZNF816 zinc finger protein 816