myocardial fiber degeneration Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description deterioration or destruction of the terminally differentiated, non-proliferative, cardiac muscle fibers, the multinucleated muscle cells of the heart (Mammalian Phenotype Ontology, MP_0004566)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0004566
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Genes

24 gene mutations causing the myocardial fiber degeneration phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ABCA5 ATP-binding cassette, sub-family A (ABC1), member 5
ACADM acyl-CoA dehydrogenase, C-4 to C-12 straight chain
ACADVL acyl-CoA dehydrogenase, very long chain
ACKR3 atypical chemokine receptor 3
ACTC1 actin, alpha, cardiac muscle 1
BAG3 BCL2-associated athanogene 3
BCL6 B-cell CLL/lymphoma 6
CHD2 chromodomain helicase DNA binding protein 2
COX1
DES desmin
DMD dystrophin
DTNA dystrobrevin, alpha
HIF3A hypoxia inducible factor 3, alpha subunit
IGHMBP2 immunoglobulin mu binding protein 2
LAMA4 laminin, alpha 4
LMNA lamin A/C
MPZL3 myelin protein zero-like 3
PPARA peroxisome proliferator-activated receptor alpha
PTCD2 pentatricopeptide repeat domain 2
SCN8A sodium channel, voltage gated, type VIII alpha subunit
SOS1 son of sevenless homolog 1 (Drosophila)
TREX1 three prime repair exonuclease 1
TRIM54 tripartite motif containing 54
VEGFA vascular endothelial growth factor A