myeloid hyperplasia Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description greater than normal number of nucleated cells of the myeloid lineage (a monocyte, granulocyte, or mast cell), found in blood or other tissue (Mammalian Phenotype Ontology, MP_0010373)
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27 gene mutations causing the myeloid hyperplasia phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ASXL1 additional sex combs like transcriptional regulator 1
BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2
CBFB core-binding factor, beta subunit
CXCR2 chemokine (C-X-C motif) receptor 2
DCC DCC netrin 1 receptor
FBXO4 F-box protein 4
FLT3 fms-related tyrosine kinase 3
HMGA1 high mobility group AT-hook 1
HPRT1 hypoxanthine phosphoribosyltransferase 1
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IKZF1 IKAROS family zinc finger 1 (Ikaros)
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
KMT2A lysine (K)-specific methyltransferase 2A
LCN2 lipocalin 2
LYN LYN proto-oncogene, Src family tyrosine kinase
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin)
PPM1D protein phosphatase, Mg2+/Mn2+ dependent, 1D
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PTPN11 protein tyrosine phosphatase, non-receptor type 11
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
SCMH1 sex comb on midleg homolog 1 (Drosophila)
SH2B3 SH2B adaptor protein 3
SLC29A3 solute carrier family 29 (equilibrative nucleoside transporter), member 3
TET2 tet methylcytosine dioxygenase 2
TINF2 TERF1 (TRF1)-interacting nuclear factor 2
TNFAIP3 tumor necrosis factor, alpha-induced protein 3