myelin sheath Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description An electrically insulating fatty layer that surrounds the axons of many neurons. It is an outgrowth of glial cells: Schwann cells supply the myelin for peripheral neurons while oligodendrocytes supply it to those of the central nervous system. (Gene Ontology, GO_0043209)
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Genes

141 proteins co-occuring with the myelin sheath cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
MBP myelin basic protein 3.27585
MAG myelin associated glycoprotein 2.7324
PLP1 proteolipid protein 1 2.14861
PMP22 peripheral myelin protein 22 2.01916
MPZ myelin protein zero 1.94321
MOG myelin oligodendrocyte glycoprotein 1.92021
CNP 2',3'-cyclic nucleotide 3' phosphodiesterase 1.89662
GALC galactosylceramidase 1.67751
CNTNAP1 contactin associated protein 1 1.56389
GAL3ST1 galactose-3-O-sulfotransferase 1 1.31627
GJB1 gap junction protein, beta 1, 32kDa 1.30873
MAL mal, T-cell differentiation protein 1.25601
KCNA2 potassium channel, voltage gated shaker related subfamily A, member 2 1.12092
MARCH7 membrane-associated ring finger (C3HC4) 7, E3 ubiquitin protein ligase 1.11939
PLLP plasmolipin 1.11582
NFASC neurofascin 1.07816
MOBP myelin-associated oligodendrocyte basic protein 1.07207
NRG1 neuregulin 1 1.07055
OPALIN oligodendrocytic myelin paranodal and inner loop protein 1.06246
PRX periaxin 1.05842
MTMR2 myotubularin related protein 2 1.0035
QKI QKI, KH domain containing, RNA binding 0.991714
UGT8 UDP glycosyltransferase 8 0.959748
EPB41L2 erythrocyte membrane protein band 4.1-like 2 0.923728
GJC2 gap junction protein, gamma 2, 47kDa 0.916243
FYN FYN proto-oncogene, Src family tyrosine kinase 0.909251
CLDN11 claudin 11 0.900426
FA2H fatty acid 2-hydroxylase 0.885628
KCNA1 potassium channel, voltage gated shaker related subfamily A, member 1 0.87733
SBF2 SET binding factor 2 0.788275
GJC3 gap junction protein, gamma 3, 30.2kDa 0.755891
B3GAT1 beta-1,3-glucuronyltransferase 1 0.75453
ABCA2 ATP-binding cassette, sub-family A (ABC1), member 2 0.749999
OMG oligodendrocyte myelin glycoprotein 0.723472
ERMN ermin, ERM-like protein 0.704831
POU3F1 POU class 3 homeobox 1 0.703507
EGR2 early growth response 2 0.684644
CA2 carbonic anhydrase II 0.673762
DHH desert hedgehog 0.658188
RTN4 reticulon 4 0.650869
CADM4 cell adhesion molecule 4 0.644429
OLIG1 oligodendrocyte transcription factor 1 0.62393
NSFL1C NSFL1 (p97) cofactor (p47) 0.605284
ASPA aspartoacylase 0.597697
PMP2 peripheral myelin protein 2 0.595593
SOX10 SRY (sex determining region Y)-box 10 0.591392
OLIG2 oligodendrocyte lineage transcription factor 2 0.583849
ELOVL7 ELOVL fatty acid elongase 7 0.552664
RTN4R reticulon 4 receptor 0.548535
NT5E 5'-nucleotidase, ecto (CD73) 0.515716
PTPRZ1 protein tyrosine phosphatase, receptor-type, Z polypeptide 1 0.512047
LINGO1 leucine rich repeat and Ig domain containing 1 0.493775
FAM126A family with sequence similarity 126, member A 0.491752
NKX2-2 NK2 homeobox 2 0.483273
ZNF185 zinc finger protein 185 (LIM domain) 0.48287
CADM3 cell adhesion molecule 3 0.477233
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8 0.475625
GPR17 G protein-coupled receptor 17 0.4672
PADI2 peptidyl arginine deiminase, type II 0.452825
NTN3 netrin 3 0.445672
KCNAB2 potassium channel, voltage gated subfamily A regulatory beta subunit 2 0.444085
TNR tenascin R 0.43696
NGFR nerve growth factor receptor 0.428678
NTN1 netrin 1 0.425924
CNTN6 contactin 6 0.421604
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1) 0.413773
GFAP glial fibrillary acidic protein 0.408699
NRCAM neuronal cell adhesion molecule 0.40247
ARHGEF10 Rho guanine nucleotide exchange factor (GEF) 10 0.401693
SERINC5 serine incorporator 5 0.398975
NDRG1 N-myc downstream regulated 1 0.395873
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) 0.381584
TDP1 tyrosyl-DNA phosphodiesterase 1 0.37697
GPM6B glycoprotein M6B 0.373132
LITAF lipopolysaccharide-induced TNF factor 0.367006
JAM3 junctional adhesion molecule 3 0.352522
EDA ectodysplasin A 0.347967
SCN8A sodium channel, voltage gated, type VIII alpha subunit 0.344556
CD9 CD9 molecule 0.336996
GDAP1 ganglioside induced differentiation associated protein 1 0.33511
SIRT2 sirtuin 2 0.330966
STX4 syntaxin 4 0.329837
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1 0.326829
AEN apoptosis enhancing nuclease 0.318579
GJB6 gap junction protein, beta 6, 30kDa 0.31783
SGCZ sarcoglycan, zeta 0.313718
DACT2 dishevelled-binding antagonist of beta-catenin 2 0.309613
NTF3 neurotrophin 3 0.30626
CALM3 calmodulin 3 (phosphorylase kinase, delta) 0.303283
CALM1 calmodulin 1 (phosphorylase kinase, delta) 0.302912
CALM2 calmodulin 2 (phosphorylase kinase, delta) 0.302912
CLIP3 CAP-GLY domain containing linker protein 3 0.30254
KIF1B kinesin family member 1B 0.299197
NCAM1 neural cell adhesion molecule 1 0.294007
ADGRG6 adhesion G protein-coupled receptor G6 0.292897
DRP2 dystrophin related protein 2 0.289199
ASB14 ankyrin repeat and SOCS box containing 14 0.277038
PADI4 peptidyl arginine deiminase, type IV 0.264215
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.262755
ETNK1 ethanolamine kinase 1 0.262025
CTSA cathepsin A 0.260931
DOCK7 dedicator of cytokinesis 7 0.260202
RANGRF RAN guanine nucleotide release factor 0.259837
CD4 CD4 molecule 0.259473
FGF17 fibroblast growth factor 17 0.258381
RAI1 retinoic acid induced 1 0.258381
GAN gigaxonin 0.257652
BDNF brain-derived neurotrophic factor 0.24713
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 0.243158
ANK3 ankyrin 3, node of Ranvier (ankyrin G) 0.237042
ALDH4A1 aldehyde dehydrogenase 4 family, member A1 0.233817
CLDN19 claudin 19 0.230958
NCAN neurocan 0.230958
IGF1 insulin-like growth factor 1 (somatomedin C) 0.229176
LGALS7 lectin, galactoside-binding, soluble, 7 0.225622
RAB3A RAB3A, member RAS oncogene family 0.224558
CERS2 ceramide synthase 2 0.21124
SELL selectin L 0.209169
RHOD ras homolog family member D 0.207108
PTEN phosphatase and tensin homolog 0.203361
KIF14 kinesin family member 14 0.198658
AKAP13 A kinase (PRKA) anchor protein 13 0.19733
ITGAD integrin, alpha D 0.195681
SLC25A37 solute carrier family 25 (mitochondrial iron transporter), member 37 0.184547
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.182422
CAPNS1 calpain, small subunit 1 0.180045
RAB24 RAB24, member RAS oncogene family 0.172468
WASL Wiskott-Aldrich syndrome-like 0.17141
FGF1 fibroblast growth factor 1 (acidic) 0.170629
SETX senataxin 0.170114
RPIA ribose 5-phosphate isomerase A 0.168598
YKT6 YKT6 v-SNARE homolog (S. cerevisiae) 0.168598
ADGRE2 adhesion G protein-coupled receptor E2 0.168101
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1 0.164089
TSPO translocator protein (18kDa) 0.162546
HNRNPDL heterogeneous nuclear ribonucleoprotein D-like 0.161275
OPHN1 oligophrenin 1 0.161275
KCNJ10 potassium channel, inwardly rectifying subfamily J, member 10 0.161068
VCAN versican 0.158129
HCG4P11 HLA complex group 4 pseudogene 11 0.156688
HLA-F major histocompatibility complex, class I, F 0.156688