mycophenolic acid-4137 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the mycophenolic acid-4137 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADM adrenomedullin
AHNAK2 AHNAK nucleoprotein 2
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
AMPD3 adenosine monophosphate deaminase 3
ANKRA2 ankyrin repeat, family A (RFXANK-like), 2
AP4S1 adaptor-related protein complex 4, sigma 1 subunit
APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
ASPH aspartate beta-hydroxylase
BMP1 bone morphogenetic protein 1
BRS3 bombesin-like receptor 3
BTG2 BTG family, member 2
C5AR2 complement component 5a receptor 2
CCNG2 cyclin G2
CD58 CD58 molecule
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CLDN17 claudin 17
CNOT4 CCR4-NOT transcription complex, subunit 4
CNTFR ciliary neurotrophic factor receptor
COBLL1 cordon-bleu WH2 repeat protein-like 1
CRY2 cryptochrome circadian clock 2
CSRP2 cysteine and glycine-rich protein 2
CTAGE5 CTAGE family, member 5
CYP2A7 cytochrome P450, family 2, subfamily A, polypeptide 7
CYP4F12 cytochrome P450, family 4, subfamily F, polypeptide 12
DCBLD2 discoidin, CUB and LCCL domain containing 2
DGCR8 DGCR8 microprocessor complex subunit
DGKA diacylglycerol kinase, alpha 80kDa
DNAJC4 DnaJ (Hsp40) homolog, subfamily C, member 4
DTX2 deltex 2, E3 ubiquitin ligase
FAS Fas cell surface death receptor
FGF18 fibroblast growth factor 18
FKBP8 FK506 binding protein 8, 38kDa
FOSL1 FOS-like antigen 1
GAD1 glutamate decarboxylase 1 (brain, 67kDa)
GADD45A growth arrest and DNA-damage-inducible, alpha
GEMIN7 gem (nuclear organelle) associated protein 7
GLS2 glutaminase 2 (liver, mitochondrial)
GPER1 G protein-coupled estrogen receptor 1
GPR87 G protein-coupled receptor 87
HFE hemochromatosis
HOXD1 homeobox D1
HRH1 histamine receptor H1
HSPA2 heat shock 70kDa protein 2
ICOSLG inducible T-cell co-stimulator ligand
IKZF1 IKAROS family zinc finger 1 (Ikaros)
IL2 interleukin 2
KCTD17 potassium channel tetramerization domain containing 17
KIAA1107 KIAA1107
KLK8 kallikrein-related peptidase 8
LIF leukemia inhibitory factor
LPCAT4 lysophosphatidylcholine acyltransferase 4
MAPK7 mitogen-activated protein kinase 7
MC5R melanocortin 5 receptor
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MR1 major histocompatibility complex, class I-related
MYH14 myosin, heavy chain 14, non-muscle
NAB1 NGFI-A binding protein 1 (EGR1 binding protein 1)
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NOL12 nucleolar protein 12
OMG oligodendrocyte myelin glycoprotein
ORAI3 ORAI calcium release-activated calcium modulator 3
PAK4 p21 protein (Cdc42/Rac)-activated kinase 4
PCDH11Y protocadherin 11 Y-linked
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PIDD1 p53-induced death domain protein 1
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PSCA prostate stem cell antigen
PTTG3P pituitary tumor-transforming 3, pseudogene
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
RHBG Rh family, B glycoprotein (gene/pseudogene)
RPL31 ribosomal protein L31
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2
SAT1 spermidine/spermine N1-acetyltransferase 1
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SESN1 sestrin 1
SH2D3A SH2 domain containing 3A
SLC48A1 solute carrier family 48 (heme transporter), member 1
SLC52A1 solute carrier family 52 (riboflavin transporter), member 1
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6
ST3GAL2 ST3 beta-galactoside alpha-2,3-sialyltransferase 2
ST3GAL4 ST3 beta-galactoside alpha-2,3-sialyltransferase 4
TAPBP TAP binding protein (tapasin)
TFEB transcription factor EB
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNFRSF10C tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain
TP53I11 tumor protein p53 inducible protein 11
TP53I3 tumor protein p53 inducible protein 3
TRAK1 trafficking protein, kinesin binding 1
TREX1 three prime repair exonuclease 1
TRIM3 tripartite motif containing 3
TRIO trio Rho guanine nucleotide exchange factor
UBE2D4 ubiquitin-conjugating enzyme E2D 4 (putative)
UHRF1BP1L UHRF1 binding protein 1-like
VWA5A von Willebrand factor A domain containing 5A
WDR76 WD repeat domain 76
WSB1 WD repeat and SOCS box containing 1
ZNF552 zinc finger protein 552

decreased expression

Symbol Name
ACTL8 actin-like 8
ANKRD11 ankyrin repeat domain 11
ARMC7 armadillo repeat containing 7
ASPHD1 aspartate beta-hydroxylase domain containing 1
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
BIN3 bridging integrator 3
BRD9 bromodomain containing 9
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B
C19ORF54 chromosome 19 open reading frame 54
C2CD2 C2 calcium-dependent domain containing 2
C5 complement component 5
C9ORF40 chromosome 9 open reading frame 40
C9ORF9 chromosome 9 open reading frame 9
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3
CBX7 chromobox homolog 7
CDHR2 cadherin-related family member 2
CDK3 cyclin-dependent kinase 3
CHRM3 cholinergic receptor, muscarinic 3
CLASP1 cytoplasmic linker associated protein 1
CLEC16A C-type lectin domain family 16, member A
CRYBB2P1 crystallin, beta B2 pseudogene 1
CUZD1 CUB and zona pellucida-like domains 1
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DVL1 dishevelled segment polarity protein 1
EFNA3 ephrin-A3
EGR3 early growth response 3
ELP6 elongator acetyltransferase complex subunit 6
EYA2 EYA transcriptional coactivator and phosphatase 2
FAM186A family with sequence similarity 186, member A
FCHSD2 FCH and double SH3 domains 2
GFOD1 glucose-fructose oxidoreductase domain containing 1
GPR19 G protein-coupled receptor 19
H2AFJ H2A histone family, member J
HCAR3 hydroxycarboxylic acid receptor 3
HDAC4 histone deacetylase 4
HIST1H1D histone cluster 1, H1d
HIST1H1E histone cluster 1, H1e
HIST1H4F histone cluster 1, H4f
HJURP Holliday junction recognition protein
HMMR hyaluronan-mediated motility receptor (RHAMM)
HOXC10 homeobox C10
HSPA1L heat shock 70kDa protein 1-like
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
INO80D INO80 complex subunit D
IRF2BP1 interferon regulatory factor 2 binding protein 1
ITGA10 integrin, alpha 10
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2
ITPKB inositol-trisphosphate 3-kinase B
KAT2A K(lysine) acetyltransferase 2A
KBTBD11 kelch repeat and BTB (POZ) domain containing 11
LRRC20 leucine rich repeat containing 20
LRRC61 leucine rich repeat containing 61
MAD1L1 MAD1 mitotic arrest deficient-like 1 (yeast)
MSL1 male-specific lethal 1 homolog (Drosophila)
MYC v-myc avian myelocytomatosis viral oncogene homolog
N4BP3 NEDD4 binding protein 3
NME5 NME/NM23 family member 5
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18
OVGP1 oviductal glycoprotein 1, 120kDa
PCF11 PCF11 cleavage and polyadenylation factor subunit
PDE8B phosphodiesterase 8B
PEX12 peroxisomal biogenesis factor 12
PIGL phosphatidylinositol glycan anchor biosynthesis, class L
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLEKHA6 pleckstrin homology domain containing, family A member 6
PLK1 polo-like kinase 1
POMT2 protein-O-mannosyltransferase 2
PPM1E protein phosphatase, Mg2+/Mn2+ dependent, 1E
PPP1R10 protein phosphatase 1, regulatory subunit 10
PTDSS2 phosphatidylserine synthase 2
RIBC2 RIB43A domain with coiled-coils 2
RLN1 relaxin 1
RPGR retinitis pigmentosa GTPase regulator
SEMA6D sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
SMG9 SMG9 nonsense mediated mRNA decay factor
SOWAHC sosondowah ankyrin repeat domain family member C
SP1 Sp1 transcription factor
SPIDR scaffolding protein involved in DNA repair
STARD13 StAR-related lipid transfer (START) domain containing 13
TERF2 telomeric repeat binding factor 2
THBS3 thrombospondin 3
TMEM104 transmembrane protein 104
TMEM57 transmembrane protein 57
TNS3 tensin 3
TRAF2 TNF receptor-associated factor 2
TTLL1 tubulin tyrosine ligase-like family member 1
VIM vimentin
VPS37C vacuolar protein sorting 37 homolog C (S. cerevisiae)
WRN Werner syndrome, RecQ helicase-like
YRDC yrdC N(6)-threonylcarbamoyltransferase domain containing
ZAK sterile alpha motif and leucine zipper containing kinase AZK
ZBTB22 zinc finger and BTB domain containing 22
ZDHHC14 zinc finger, DHHC-type containing 14
ZFP69B ZFP69 zinc finger protein B
ZIC1 Zic family member 1
ZNF165 zinc finger protein 165
ZNF516 zinc finger protein 516